메뉴 건너뛰기




Volumn 79, Issue 2, 2004, Pages 296-303

N-acetylcysteine prevents lung inflammation after short-term inhalation exposure to concentrated ambient particles

Author keywords

CAPs; Inflammation; Oxidative stress; Particulate air pollution; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ALUMINUM; ANTIOXIDANT; CARBONYL DERIVATIVE; CHROMIUM; IRON; LACTATE DEHYDROGENASE; PROTEIN; SILICON; SODIUM; THIOBARBITURIC ACID REACTIVE SUBSTANCE; ZINC;

EID: 2942744826     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh122     Document Type: Article
Times cited : (108)

References (37)
  • 1
    • 0026635997 scopus 로고
    • Protection by N-acetylcysteine of the histopathological and cytogenetical damage produced by exposure of rats to cigarette smoke
    • Balansky, R. B., D'Agostino, F., Zanacchi, P., and DeFlora, S. (1992). Protection by N-acetylcysteine of the histopathological and cytogenetical damage produced by exposure of rats to cigarette smoke. Cancer Lett. 64, 123-131.
    • (1992) Cancer Lett. , vol.64 , pp. 123-131
    • Balansky, R.B.1    D'Agostino, F.2    Zanacchi, P.3    DeFlora, S.4
  • 3
    • 0030586689 scopus 로고    scopus 로고
    • In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation
    • Blackwell, T. S., Blackwell, T. R., Holden, E. P., Christman, B. W., and Christman, J. W. (1996). In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation. J. Immunol. 157, 1630-1637.
    • (1996) J. Immunol. , vol.157 , pp. 1630-1637
    • Blackwell, T.S.1    Blackwell, T.R.2    Holden, E.P.3    Christman, B.W.4    Christman, J.W.5
  • 4
    • 0035884859 scopus 로고    scopus 로고
    • Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise
    • Childs, A., Jacobs, C., Kaminiski, T., Halliwell, B., and Leeuwenburgh, C. (2001). Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise. Free Radic. Biol. Med. 31, 745-753.
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 745-753
    • Childs, A.1    Jacobs, C.2    Kaminiski, T.3    Halliwell, B.4    Leeuwenburgh, C.5
  • 6
    • 0032784341 scopus 로고    scopus 로고
    • Urban air particulate inhalation alters pulmonary function and induces pulmonary inflammation in a rodent model of chronic bronchitis
    • Clarke, R. W., Catalano, P. J., Krishna Murthy, G. G., Sioutas, C., Paulauskis, J., Coull, B., Ferguson, S., and Godleski, J. J. (1999). Urban air particulate inhalation alters pulmonary function and induces pulmonary inflammation in a rodent model of chronic bronchitis. Inhal. Toxicol. 11, 637-656.
    • (1999) Inhal. Toxicol. , vol.11 , pp. 637-656
    • Clarke, R.W.1    Catalano, P.J.2    Krishna Murthy, G.G.3    Sioutas, C.4    Paulauskis, J.5    Coull, B.6    Ferguson, S.7    Godleski, J.J.8
  • 8
    • 0035025056 scopus 로고    scopus 로고
    • Protective effects of N-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat
    • Cuzzocrea, S., Mazzon, E., Dugo, L., Serraino, I., Centorrino, T., DeSarro, A., and Caputti, A. P. (2001). Protective effects of N-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat. FASEB J. 15, 1187-1200.
    • (2001) FASEB J. , vol.15 , pp. 1187-1200
    • Cuzzocrea, S.1    Mazzon, E.2    Dugo, L.3    Serraino, I.4    Centorrino, T.5    DeSarro, A.6    Caputti, A.P.7
  • 9
    • 0033972465 scopus 로고    scopus 로고
    • Convergence of redox sensitive and mitogen-activated protein kinase signaling pathways in tumor necrosis factor-alpha-mediated monocyte chemoattractant protein-1 in vaacular smooth muscle cells 9
    • De Keulenaer, G. W., Ushio-Fukai, M., Yin, O., Chung, A. B., Lyons, P. R., Ishizaka, N., Rengarajan, K., Taylor, W. F., Alexander, R. W., and Griendling, K. K. (2000). Convergence of redox sensitive and mitogen-activated protein kinase signaling pathways in tumor necrosis factor-alpha-mediated monocyte chemoattractant protein-1 in vaacular smooth muscle cells. Arteroscler. Thromb. Vasc. Biol. 20, 385-391.
    • (2000) Arteroscler. Thromb. Vasc. Biol. , vol.20 , pp. 385-391
    • De Keulenaer, G.W.1    Ushio-Fukai, M.2    Yin, O.3    Chung, A.B.4    Lyons, P.R.5    Ishizaka, N.6    Rengarajan, K.7    Taylor, W.F.8    Alexander, R.W.9    Griendling, K.K.10
  • 10
    • 0037235805 scopus 로고    scopus 로고
    • The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types
    • Dick, C. A. J., Brown, D. M., Donaldson, K., and Stone, V. (2003). The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types. Inhal. Toxicol. 15, 39-52.
    • (2003) Inhal. Toxicol. , vol.15 , pp. 39-52
    • Dick, C.A.J.1    Brown, D.M.2    Donaldson, K.3    Stone, V.4
  • 11
    • 0025127633 scopus 로고
    • Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal
    • Esterbauer, H., and Cheeseman, K. H. (1990). Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal. Meth. Enzymol. 186, 407-421.
    • (1990) Meth. Enzymol. , vol.186 , pp. 407-421
    • Esterbauer, H.1    Cheeseman, K.H.2
  • 13
    • 0015007720 scopus 로고
    • Micro method for the determination of reactive carbonyl groups in proteins and peptides using 2,4-dinitrophenyl-hydrazine
    • Fields, R., and Dixon, H. B. F. (1971). Micro method for the determination of reactive carbonyl groups in proteins and peptides using 2,4-dinitrophenyl-hydrazine. Biochem. J. 121, 587-593.
    • (1971) Biochem. J. , vol.121 , pp. 587-593
    • Fields, R.1    Dixon, H.B.F.2
  • 14
    • 0035881065 scopus 로고    scopus 로고
    • Inflammatory lung injury after bronchial instillation of air pollution particles
    • Ghio, A. J., and Devlin, R. B. (2001). Inflammatory lung injury after bronchial instillation of air pollution particles. Am. J. Respir. Crit. Care Med. 164, 704-708.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , pp. 704-708
    • Ghio, A.J.1    Devlin, R.B.2
  • 15
    • 0033829784 scopus 로고    scopus 로고
    • Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers
    • Ghio, A. J., Kim, C., and Devlin, R. B. (2001). Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers. Am. J. Respir. Crit. Care Med. 162, 981-988.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.162 , pp. 981-988
    • Ghio, A.J.1    Kim, C.2    Devlin, R.B.3
  • 17
    • 0036054940 scopus 로고    scopus 로고
    • Rapid increases in the steady-state concentration of reactive oxygen species in the lungs and heart after particulate air pollution inhalation
    • Gurgueira, S. A., Lawrence, J., Coull, B., Krishna Murthy, G. G., and González-Flecha, B. (2002). Rapid increases in the steady-state concentration of reactive oxygen species in the lungs and heart after particulate air pollution inhalation. Environ. Health Perspect. 110, 749-755.
    • (2002) Environ. Health Perspect. , vol.110 , pp. 749-755
    • Gurgueira, S.A.1    Lawrence, J.2    Coull, B.3    Krishna Murthy, G.G.4    González-Flecha, B.5
  • 18
    • 0021991151 scopus 로고
    • Inhalable particles and pulmonary host defense: In vivo and in vitro effects of ambient air and combustion particles
    • Hatch, G. E., Boykin, E., Graham, J. A., Lewtas, J., Pott, F., Loud, K., and Mumford, J. L. (1985). Inhalable particles and pulmonary host defense: In vivo and in vitro effects of ambient air and combustion particles. Environ. Res. 36, 67-80.
    • (1985) Environ. Res. , vol.36 , pp. 67-80
    • Hatch, G.E.1    Boykin, E.2    Graham, J.A.3    Lewtas, J.4    Pott, F.5    Loud, K.6    Mumford, J.L.7
  • 20
    • 0034654155 scopus 로고    scopus 로고
    • Residual oil fly ash induces cytotoxicity and mucin secretion by guinea pig tracheal epithelial cells via an oxidant-dependent mechanism
    • Jiang, N., Dreher, K. L., Dve, J. A., Li, Y., Richards, J. H., Martin, L. D., and Adler, K. B. (2002). Residual oil fly ash induces cytotoxicity and mucin secretion by guinea pig tracheal epithelial cells via an oxidant-dependent mechanism. Tox. Appl. Pharmacol. 163, 221-230.
    • (2002) Tox. Appl. Pharmacol. , vol.163 , pp. 221-230
    • Jiang, N.1    Dreher, K.L.2    Dve, J.A.3    Li, Y.4    Richards, J.H.5    Martin, L.D.6    Adler, K.B.7
  • 25
    • 0028291974 scopus 로고
    • Carbonyl assays for determination of oxidatively modified proteins
    • Levine, R. L., Williams, J. A., Stadtman, E. R., and Shacter, E. (1994). Carbonyl assays for determination of oxidatively modified proteins. Meth. Enzymol.. 233, 346-357.
    • (1994) Meth. Enzymol. , vol.233 , pp. 346-357
    • Levine, R.L.1    Williams, J.A.2    Stadtman, E.R.3    Shacter, E.4
  • 26
    • 0037108605 scopus 로고    scopus 로고
    • Comparison of the pro-oxidant and pro-inflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages
    • Li, N., Wand, M., Oberley, T. D., Sempf, J. M., and Nel, A. E. (2002). Comparison of the pro-oxidant and pro-inflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages. J. Immunol. 169, 4531-4541.
    • (2002) J. Immunol. , vol.169 , pp. 4531-4541
    • Li, N.1    Wand, M.2    Oberley, T.D.3    Sempf, J.M.4    Nel, A.E.5
  • 27
    • 0029849554 scopus 로고    scopus 로고
    • Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro
    • Li, X. Y., Gilmour, P. S., Donaldson, K., and MacNee, W. (1996). Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro. Thorax 51, 1216-1222.
    • (1996) Thorax , vol.51 , pp. 1216-1222
    • Li, X.Y.1    Gilmour, P.S.2    Donaldson, K.3    MacNee, W.4
  • 28
    • 2142797865 scopus 로고    scopus 로고
    • In vivo and in vitro proinflammatory effects of particulate air pollution (PM10)
    • Li, X. Y., Gilmour, P. S., Donaldson, K., and MacNee, W. (1997). In vivo and in vitro proinflammatory effects of particulate air pollution (PM10). Environ. Health Perspect. 105 (Suppl. 5), 1279-1283.
    • (1997) Environ. Health Perspect. , vol.105 , Issue.SUPPL. 5 , pp. 1279-1283
    • Li, X.Y.1    Gilmour, P.S.2    Donaldson, K.3    MacNee, W.4
  • 30
    • 0033740853 scopus 로고    scopus 로고
    • Differential anti-inflammatory and anti-oxidative effects of dexamethasone and N-acetylcysteine in endotoxin-induced lung inflammation
    • Rockse, D., Lilliebook, B., Larsson, R., Jobansson, T., and Bucht, A. (2000). Differential anti-inflammatory and anti-oxidative effects of dexamethasone and N-acetylcysteine in endotoxin-induced lung inflammation. Clin. Exp. Immunol. 122, 249-256.
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 249-256
    • Rockse, D.1    Lilliebook, B.2    Larsson, R.3    Jobansson, T.4    Bucht, A.5
  • 32
    • 0033911097 scopus 로고    scopus 로고
    • Air pollution and health in urban areas
    • Schwela, D. (2000). Air pollution and health in urban areas. Rev. Environ. Health 15, 13-42.
    • (2000) Rev. Environ. Health , vol.15 , pp. 13-42
    • Schwela, D.1
  • 33
    • 0033845110 scopus 로고    scopus 로고
    • Inhaled particulate matter causes expression of nuclear factor (NF)-kappaB-related genes and oxidant-dependent NF-kappaB activation in vitro
    • Shukla, A., Timblin, C., BeruBe, K., Gordon, T., McKinney, W., Driscoll, K., Vacek, P., and Mossman, B. T. (2000). Inhaled particulate matter causes expression of nuclear factor (NF)-kappaB-related genes and oxidant-dependent NF-kappaB activation in vitro. Am. J. Resp. Cell Mol. Biol. 23, 182-187.
    • (2000) Am. J. Resp. Cell Mol. Biol. , vol.23 , pp. 182-187
    • Shukla, A.1    Timblin, C.2    BeruBe, K.3    Gordon, T.4    McKinney, W.5    Driscoll, K.6    Vacek, P.7    Mossman, B.T.8
  • 34
    • 0028947496 scopus 로고
    • A technique to expose animals to concentrated fine ambient aerosols
    • Sioutas, C., Koutrakis, P., and Burton, R. M. (1995). A technique to expose animals to concentrated fine ambient aerosols. Envrion. Health Perspect. 103, 172-177.
    • (1995) Envrion. Health Perspect. , vol.103 , pp. 172-177
    • Sioutas, C.1    Koutrakis, P.2    Burton, R.M.3
  • 35
    • 0036385848 scopus 로고    scopus 로고
    • N-acetylcysteine effect on luminol-dependent chemiluminescence pattern of reactive oxygen species generation by human polymorphonuclear leukocytes
    • Stolarek, R., Biaasiewicz, P., and Mowak, D. (2002). N-acetylcysteine effect on luminol-dependent chemiluminescence pattern of reactive oxygen species generation by human polymorphonuclear leukocytes. Pulmonary Pharmacology & Therapeutics 15, 385-392.
    • (2002) Pulmonary Pharmacology & Therapeutics , vol.15 , pp. 385-392
    • Stolarek, R.1    Biaasiewicz, P.2    Mowak, D.3
  • 36
    • 0037090226 scopus 로고    scopus 로고
    • Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense
    • Villa, P., Saccani, A., Sica, A., and Ghezzi, P. (2002). Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense. J. Infect. Diseases 185, 1115-1120.
    • (2002) J. Infect. Diseases , vol.185 , pp. 1115-1120
    • Villa, P.1    Saccani, A.2    Sica, A.3    Ghezzi, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.