-
1
-
-
0036007687
-
Metabolomics-the link between genotypes and phenotypes
-
Fiehn, O. Metabolomics-the link between genotypes and phenotypes. Plant Mol. Biol. (2002) 48: 155-171.
-
(2002)
Plant Mol. Biol.
, vol.48
, pp. 155-171
-
-
Fiehn, O.1
-
2
-
-
0036855391
-
Metabolic profiling using direct infusion electrospray ionisation mass spectrometry for the characterisation of olive oils
-
Goodacre, R., Vaidyanathan, S., Bianchi, G. and Kell, D.B. Metabolic profiling using direct infusion electrospray ionisation mass spectrometry for the characterisation of olive oils. Analyst. (2002)127: 1457-1462.
-
(2002)
Analyst.
, vol.127
, pp. 1457-1462
-
-
Goodacre, R.1
Vaidyanathan, S.2
Bianchi, G.3
Kell, D.B.4
-
3
-
-
2942676743
-
Metabolomics and systems biology; making sense of the soup
-
Kell, D.B. Metabolomics and systems biology; making sense of the soup. Curr. Opin. Microbiol. (2004) 7: 296-307.
-
(2004)
Curr. Opin. Microbiol.
, vol.7
, pp. 296-307
-
-
Kell, D.B.1
-
4
-
-
0345270397
-
Plant metabolomics: Large-scale phytochemistry in the functional genomics era
-
Sumner, L.W., Mendes, P. and Dixon, R.A. Plant metabolomics: large-scale phytochemistry in the functional genomics era. Phytochemistry (2003) 62: 817-836.
-
(2003)
Phytochemistry
, vol.62
, pp. 817-836
-
-
Sumner, L.W.1
Mendes, P.2
Dixon, R.A.3
-
5
-
-
0032168794
-
Systematic functional analysis of the yeast genome
-
Oliver, S.G., Winson, M.K., Kell, D.B. and Baganz, F. Systematic functional analysis of the yeast genome. Trends Biotechnol. (1998)16: 373-378.
-
(1998)
Trends Biotechnol.
, vol.16
, pp. 373-378
-
-
Oliver, S.G.1
Winson, M.K.2
Kell, D.B.3
Baganz, F.4
-
6
-
-
10744223858
-
Genomic scale profiling of nutrient and trace elements in Arabidopsis thaliana
-
Lahner, B., Gong, J., Mahmoudian, M., Smith, E.L., Abid, K.B., Rogers, E.E., Guerinot, M.L., Harper, J.F., Ward, J.M., McIntyre, L., Schroeder, J.I. and Salt, D.I. Genomic scale profiling of nutrient and trace elements in Arabidopsis thaliana. Nat. Biotechnol. (2003) 21: 1215-1221.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1215-1221
-
-
Lahner, B.1
Gong, J.2
Mahmoudian, M.3
Smith, E.L.4
Abid, K.B.5
Rogers, E.E.6
Guerinot, M.L.7
Harper, J.F.8
Ward, J.M.9
McIntyre, L.10
Schroeder, J.I.11
Salt, D.I.12
-
7
-
-
0037462046
-
Metabolite profiling of tomato (Lycopersicon esculentum) using 1H NMR spectroscopy as a tool to detect potential unintended effects following a genetic modification
-
Le Gall, G., Colquhoun, I.J., Davis, A.L., Collins, G. L. and Verhoeyen, M.E. Metabolite profiling of tomato (Lycopersicon esculentum) using 1H NMR spectroscopy as a tool to detect potential unintended effects following a genetic modification. J. Agric. Food Chem. (2003) 51: 2447-2456.
-
(2003)
J. Agric. Food Chem.
, vol.51
, pp. 2447-2456
-
-
Le Gall, G.1
Colquhoun, I.J.2
Davis, A.L.3
Collins, G.L.4
Verhoeyen, M.E.5
-
8
-
-
0036099407
-
Flow-injection electrospray ionisation mass spectrometry of crude cell extracts for high-throughput bacterial identification
-
Vaidyanathan, S., Kell, D.B. and Goodacre, R. Flow-injection electrospray ionisation mass spectrometry of crude cell extracts for high-throughput bacterial identification. J. Am. Soc. Mass Spectrom. (2002) 13: 118-128.
-
(2002)
J. Am. Soc. Mass Spectrom.
, vol.13
, pp. 118-128
-
-
Vaidyanathan, S.1
Kell, D.B.2
Goodacre, R.3
-
9
-
-
0036624293
-
Metabolomics and biochemical profiling in drug discovery and development
-
Watkins, S. M. and German, J.B. Metabolomics and biochemical profiling in drug discovery and development. Curr. Opin. Mol. Ther. (2002) 4: 224-228.
-
(2002)
Curr. Opin. Mol. Ther.
, vol.4
, pp. 224-228
-
-
Watkins, S.M.1
German, J.B.2
-
10
-
-
0034105138
-
'Slave' metabolites and enzymes. A rapid way of delineating metabolic control
-
Teusink, B. and Westerhoff, H.V. 'Slave' metabolites and enzymes. A rapid way of delineating metabolic control. Eur. J. Biochem. (2000) 267: 1889-1893.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 1889-1893
-
-
Teusink, B.1
Westerhoff, H.V.2
-
11
-
-
41849083955
-
High-throughput 1H NMR-based metabolic analysis of human serum and urine for large-scale epidemiological studies: Validation study
-
Barton, R.H., Nicholson, J.K., Elliott, P. and Holmes, E. High-throughput 1H NMR-based metabolic analysis of human serum and urine for large-scale epidemiological studies: validation study. Int. J. Epidemiol. (2008) 37: 131-140.
-
(2008)
Int. J. Epidemiol.
, vol.37
, pp. 131-140
-
-
Barton, R.H.1
Nicholson, J.K.2
Elliott, P.3
Holmes, E.4
-
12
-
-
64649089947
-
Cross-platform comparison of methods for quantitative metabolomics of primary metabolism
-
Buscher, J.M., Czernik, D., Ewald, J.C., Sauer, U. and Zamboni, N. Cross-platform comparison of methods for quantitative metabolomics of primary metabolism. Anal. Chem. (2009) 81: 2135-2143.
-
(2009)
Anal. Chem.
, vol.81
, pp. 2135-2143
-
-
Buscher, J.M.1
Czernik, D.2
Ewald, J.C.3
Sauer, U.4
Zamboni, N.5
-
13
-
-
21044447078
-
Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets
-
Jonsson, P. et al., Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets. Analyst. (2005) 130: 701-707.
-
(2005)
Analyst.
, vol.130
, pp. 701-707
-
-
Jonsson, P.1
-
14
-
-
38349103941
-
Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics
-
Nordstrom, A., Want, E., Northen, T., Lehtio, J. and Siuzdak, G. Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics. Anal. Chem. (2008) 80: 421-429.
-
(2008)
Anal. Chem.
, vol.80
, pp. 421-429
-
-
Nordstrom, A.1
Want, E.2
Northen, T.3
Lehtio, J.4
Siuzdak, G.5
-
15
-
-
32444451016
-
Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry
-
Want, E.J. et al., Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry. Anal. Chem. (2006) 78: 743-752.
-
(2006)
Anal. Chem.
, vol.78
, pp. 743-752
-
-
Want, E.J.1
-
16
-
-
62649151803
-
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
-
Wikoff, W.R. et al., Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc. Natl Acad. Sci. USA. (2009) 106: 3698-3703.
-
(2009)
Proc. Natl Acad. Sci. USA.
, vol.106
, pp. 3698-3703
-
-
Wikoff, W.R.1
-
17
-
-
77952545479
-
Metabolic oxidation regulates embryonic stem cell differentiation
-
Yanes, O. et al., Metabolic oxidation regulates embryonic stem cell differentiation. Nature Chem. Biol. (2010) 6: 411-417.
-
(2010)
Nature Chem. Biol.
, vol.6
, pp. 411-417
-
-
Yanes, O.1
-
18
-
-
32444446805
-
XCMS: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification
-
Smith, C.A., Want, E.J., O'Maille, G., Abagyan, R. and Siuzdak, G. XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal. Chem. (2006)78: 779-787.
-
(2006)
Anal. Chem.
, vol.78
, pp. 779-787
-
-
Smith, C.A.1
Want, E.J.2
O'Maille, G.3
Abagyan, R.4
Siuzdak, G.5
-
19
-
-
33845869336
-
MathDAMP: A package for differential analysis of metabolite profiles
-
Baran, R. et al., MathDAMP: a package for differential analysis of metabolite profiles. BMC Bioinformatics. (2006) 7: 530.
-
(2006)
BMC Bioinformatics.
, vol.7
, pp. 530
-
-
Baran, R.1
-
20
-
-
65249132985
-
MetAlign: Interface-driven, versatile metabolomics tool for hyphenated full-scan mass spectrometry data preprocessing
-
Lommen, A. MetAlign: interface-driven, versatile metabolomics tool for hyphenated full-scan mass spectrometry data preprocessing. Anal. Chem. (2009) 81: 3079-3086.
-
(2009)
Anal. Chem.
, vol.81
, pp. 3079-3086
-
-
Lommen, A.1
-
21
-
-
33644867564
-
MZmine: Toolbox for processing and visualization of mass spectrometry based molecular profile data
-
Katajamaa, M., Miettinen, J. And Oresic, M. MZmine: toolbox for processing and visualization of mass spectrometry based molecular profile data. Bioinformatics. (2006) 22: 634-636.
-
(2006)
Bioinformatics.
, vol.22
, pp. 634-636
-
-
Katajamaa, M.1
Miettinen, J.2
Oresic, M.3
-
22
-
-
25444526868
-
Processing methods for differential analysis of LC/MS profile data
-
Katajamaa, M. and Oresic, M. Processing methods for differential analysis of LC/MS profile data. BMC Bioinformatics. (2005) 6: 179.
-
(2005)
BMC Bioinformatics.
, vol.6
, pp. 179
-
-
Katajamaa, M.1
Oresic, M.2
-
23
-
-
79551507196
-
Metabolomics: From small molecules to big ideas
-
Baker, M. Metabolomics: from small molecules to big ideas. Nature Methods (2011) 8: 117-121.
-
(2011)
Nature Methods
, vol.8
, pp. 117-121
-
-
Baker, M.1
-
24
-
-
84858790233
-
Metabolomics: The apogee of the omics trilogy
-
Gary, J.P., Oscar, Y. and Gary, S. Metabolomics: the apogee of the omics trilogy. Molecular cell biology. (2012)13: 263-269.
-
(2012)
Molecular cell biology.
, vol.13
, pp. 263-269
-
-
Gary, J.P.1
Oscar, Y.2
Gary, S.3
-
25
-
-
33748603444
-
Metabolomics: Current technologies and future trends
-
Katherine, H., Daniel, R. B. and Royston, G. Metabolomics: current technologies and future trends. Proteomics. (2006) 6: 4716-4723.
-
(2006)
Proteomics.
, vol.6
, pp. 4716-4723
-
-
Katherine, H.1
Daniel, R.B.2
Royston, G.3
-
26
-
-
0036380802
-
Metabolic control in integrated biochemical systems
-
De la Fuente, A., Snoep, J.L., Westerhoff, H.V. and Mendes, P. Metabolic control in integrated biochemical systems. Eur. J. Biochem. (2002) 269: 4399-4408.
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 4399-4408
-
-
De la Fuente, A.1
Snoep, J.L.2
Westerhoff, H.V.3
Mendes, P.4
-
27
-
-
0031686598
-
Effect of slow growth on metabolism of Eschericha coli, as revealed by global metabolite pool ("metabolome") analysis
-
Tweeddale, H., Notley-McRobb, L. and Ferenci, T. Effect of slow growth on metabolism of Eschericha coli, as revealed by global metabolite pool ("metabolome") analysis. J. Bacteriol. (1998) 180: 5109-5116.
-
(1998)
J. Bacteriol.
, vol.180
, pp. 5109-5116
-
-
Tweeddale, H.1
Notley-McRobb, L.2
Ferenci, T.3
-
28
-
-
20344367794
-
NMR-derived developmental metabolic trajectories: An approach for visualizing the toxic actions of trichloroethylene during embryogenesis
-
Viant, M.R., Pincetich, C.A., De Ropp, J.S. and Tjeerdema, R.S. NMR-derived developmental metabolic trajectories: an approach for visualizing the toxic actions of trichloroethylene during embryogenesis. Metabolomics. (2005) 1: 149-158.
-
(2005)
Metabolomics.
, vol.1
, pp. 149-158
-
-
Viant, M.R.1
Pincetich, C.A.2
de Ropp, J.S.3
Tjeerdema, R.S.4
-
29
-
-
0035881207
-
Quantification of intracellular metabolites in Eschericha coli K12 using liquid chromatographic-electrospray ionization tandem mass spectrometric techniques
-
Buchholz, A., Takors, R. and Wandrey, C. Quantification of intracellular metabolites in Eschericha coli K12 using liquid chromatographic-electrospray ionization tandem mass spectrometric techniques. Anal. Biochem. (2001) 295: 129-137.
-
(2001)
Anal. Biochem.
, vol.295
, pp. 129-137
-
-
Buchholz, A.1
Takors, R.2
Wandrey, C.3
-
30
-
-
28044440100
-
Global metabolite analysis of yeast: Evaluation of sample preparation methods
-
Villas-Boas, S.G., Hojer-Pedersen, J., Akesson, M., Smeds-gaard, J. and Nielsen, J. Global metabolite analysis of yeast: evaluation of sample preparation methods. Yeast. (2005) 22: 1155-1169.
-
(2005)
Yeast.
, vol.22
, pp. 1155-1169
-
-
Villas-Boas, S.G.1
Hojer-Pedersen, J.2
Akesson, M.3
Smeds-gaard, J.4
Nielsen, J.5
-
31
-
-
18844406001
-
Measuring the metabolome: Current analytical technologies
-
Dunn, W.B., Bailey, N.J. and Johnson, H.E. Measuring the metabolome: current analytical technologies. Analyst. (2005) 130: 606-625.
-
(2005)
Analyst.
, vol.130
, pp. 606-625
-
-
Dunn, W.B.1
Bailey, N.J.2
Johnson, H.E.3
-
32
-
-
16244402990
-
Metabolomics; current analytical platforms and methodologies, Trends Anal
-
Dunn, W.B. and Ellis, D.I. Metabolomics; current analytical platforms and methodologies, Trends Anal. Chem. (2005) 24: 285-294.
-
(2005)
Chem.
, vol.24
, pp. 285-294
-
-
Dunn, W.B.1
Ellis, D.I.2
-
33
-
-
65249132985
-
MetAlign: Interface-driven, versatile metabolomics tool for hyphenated full-scan mass spectrometry data preprocessing
-
Lommen, A. MetAlign: interface-driven, versatile metabolomics tool for hyphenated full-scan mass spectrometry data preprocessing. Anal. Chem. (2009) 81: 3079-3086.
-
(2009)
Anal. Chem.
, vol.81
, pp. 3079-3086
-
-
Lommen, A.1
-
34
-
-
0033757963
-
Metabolite profiling for plant functional genomics
-
Fiehn, O., Kopka, J., Dormann, P., Altmann, T., Trethewey, N.R. and Willmitzer, L. Metabolite profiling for plant functional genomics. Nat. Biotechnol. (2000) 18: 1157-1161.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 1157-1161
-
-
Fiehn, O.1
Kopka, J.2
Dormann, P.3
Altmann, T.4
Trethewey, N.R.5
Willmitzer, L.6
-
35
-
-
21344474748
-
Comprehensive two dimensional gas chromatography-time of flight mass spectrometry for high resolution metabolomics: Biomarker discovery on spleen tissue extracts of obese NZO compared to lean C57BL/6 mice
-
Welthagen, W., Shellie, R.A., Spranger, J.M., Ristow, M., Zimmermann, R. and Fiehn, O. Comprehensive two dimensional gas chromatography-time of flight mass spectrometry for high resolution metabolomics: biomarker discovery on spleen tissue extracts of obese NZO compared to lean C57BL/6 mice. Metabolomics. (2005) 1: 65-73.
-
(2005)
Metabolomics.
, vol.1
, pp. 65-73
-
-
Welthagen, W.1
Shellie, R.A.2
Spranger, J.M.3
Ristow, M.4
Zimmermann, R.5
Fiehn, O.6
-
36
-
-
10044257788
-
Metabolomic applications of electrochemistry/mass spectrometry
-
Gamache, P.H. Metabolomic applications of electrochemistry/mass spectrometry. J. Am. Soc. Mass Spectrom. (2004)15: 1717-1726.
-
(2004)
J. Am. Soc. Mass Spectrom.
, vol.15
, pp. 1717-1726
-
-
Gamache, P.H.1
-
37
-
-
12944320855
-
HPLC-MS-based methods for the study of metabolomics
-
Wilson, I.D., Plumb, R., Granger, J., Major, H., Williams, R. and Lenz, E.A. HPLC-MS-based methods for the study of metabolomics. J. Chro-matogr. B Analyt. Technol. Biomed. Life Sci. (2005) 817: 67-76.
-
(2005)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.817
, pp. 67-76
-
-
Wilson, I.D.1
Plumb, R.2
Granger, J.3
Major, H.4
Williams, R.5
Lenz, E.A.6
-
38
-
-
0345168159
-
Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics
-
Tolstikov, V.V., Lommen, A., Nakanishi, K., Tanaka, N. and Fiehn, O. Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics. Anal. Chem. (2003) 75: 6737-6740.
-
(2003)
Anal. Chem.
, vol.75
, pp. 6737-6740
-
-
Tolstikov, V.V.1
Lommen, A.2
Nakanishi, K.3
Tanaka, N.4
Fiehn, O.5
-
39
-
-
0037093109
-
Simultaneous determination of anionic intermediates for Bacillus subtilis metabolic pathways by capillary electrophoresis electrospray ionization mass spectrometry
-
Soga, T., Ueno, Y., Naraoka, H., Ohashi, Y., Tomita, M. and Nishioka, T. Simultaneous determination of anionic intermediates for Bacillus subtilis metabolic pathways by capillary electrophoresis electrospray ionization mass spectrometry. Anal. Chem. (2002) 74: 2233-2239.
-
(2002)
Anal. Chem.
, vol.74
, pp. 2233-2239
-
-
Soga, T.1
Ueno, Y.2
Naraoka, H.3
Ohashi, Y.4
Tomita, M.5
Nishioka, T.6
-
40
-
-
0242569355
-
Quantitative metabolome analysis using capillary electrophoresis mass spectrometry
-
Soga, T., Ohashi, Y., Ueno, Y., Naraoka, H., Tomita, M. and Nishioka, T. Quantitative metabolome analysis using capillary electrophoresis mass spectrometry. J. Proteome Res. (2003) 2: 488-494.
-
(2003)
J. Proteome Res.
, vol.2
, pp. 488-494
-
-
Soga, T.1
Ohashi, Y.2
Ueno, Y.3
Naraoka, H.4
Tomita, M.5
Nishioka, T.6
-
41
-
-
0032694577
-
'Metabolomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
Nicholson, J.K., Lindon, J.C. and Holmes, E. 'Metabolomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica. (1999) 29: 1181-1189.
-
(1999)
Xenobiotica.
, vol.29
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
42
-
-
0346366560
-
Application of high-throughput Fourier-transform infrared spectroscopy in toxicology studies: Contribution to a study on the development of an animal model for idiosyncratic toxicity
-
Harrigan, G.G., LaPlante, R.H., Cosma, G.N., Cockerell, G., Goodacre, R., Maddox, J.F., Luyendyk, J.P., Ganey, P.E. and Roth, R.A. Application of high-throughput Fourier-transform infrared spectroscopy in toxicology studies: contribution to a study on the development of an animal model for idiosyncratic toxicity. Toxicol. Lett. (2004)146: 197-205.
-
(2004)
Toxicol. Lett.
, vol.146
, pp. 197-205
-
-
Harrigan, G.G.1
LaPlante, R.H.2
Cosma, G.N.3
Cockerell, G.4
Goodacre, R.5
Maddox, J.F.6
Luyendyk, J.P.7
Ganey, P.E.8
Roth, R.A.9
-
43
-
-
33746449986
-
Metabolic fingerprinting in disease diagnosis: Biomedical applications of infrared and raman spectroscopy
-
Ellis, D.I. and Goodacre, R. Metabolic fingerprinting in disease diagnosis: biomedical applications of infrared and raman spectroscopy. Analyst. (2006) 131: 875-885.
-
(2006)
Analyst.
, vol.131
, pp. 875-885
-
-
Ellis, D.I.1
Goodacre, R.2
-
44
-
-
13244259596
-
Application of metabolite profiling to the identification of traits in a population of tomato introgression lines
-
Overy, S.A., Walker, H.J., Malone, S., Howard, T.P., Baxter, C.J., Sweetlove, L.J., Hill, S.A. and Quick, W.P. Application of metabolite profiling to the identification of traits in a population of tomato introgression lines. J. Exp. Bot. (2005) 56: 287-296.
-
(2005)
J. Exp. Bot.
, vol.56
, pp. 287-296
-
-
Overy, S.A.1
Walker, H.J.2
Malone, S.3
Howard, T.P.4
Baxter, C.J.5
Sweetlove, L.J.6
Hill, S.A.7
Quick, W.P.8
-
45
-
-
0036404889
-
Nontargeted metabolome analysis by use of Fourier transform ion cyclotron mass spectrometry
-
Aharoni, A., Ric de Vos, C.H., Verhoeven, H.A., Maliepaard, C.A., Kruppa, G., Bino, R. and D Goodenowe, D.B. Nontargeted metabolome analysis by use of Fourier transform ion cyclotron mass spectrometry. Omics (2003) 6: 217-234.
-
(2003)
Omics
, vol.6
, pp. 217-234
-
-
Aharoni, A.1
Ric de Vos, C.H.2
Verhoeven, H.A.3
Maliepaard, C.A.4
Kruppa, G.5
Bino, R.6
Goodenowe, D.B.7
-
46
-
-
22144493335
-
Metabolic targeted therapy of cancer: Current tracer technologies and future drug design strategies in the old metabolic network
-
Boros, L.G. Metabolic targeted therapy of cancer: current tracer technologies and future drug design strategies in the old metabolic network. Metabolomics. (2005) 1: 11-15.
-
(2005)
Metabolomics.
, vol.1
, pp. 11-15
-
-
Boros, L.G.1
-
47
-
-
58149202163
-
HMDB: A knowledgebase for the human metabolome
-
Wishart, D.S. et al., HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. (2009) 37: 603-610.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 603-610
-
-
Wishart, D.S.1
-
48
-
-
32444432587
-
METLIN: A metabolite mass spectral database
-
Smith, C.A. et al., METLIN: a metabolite mass spectral database. Ther. Drug Monit. (2005) 27: 747-751.
-
(2005)
Ther. Drug Monit.
, vol.27
, pp. 747-751
-
-
Smith, C.A.1
|