Association between PIN1 promoter polymorphisms and risk of nasopharyngeal carcinoma

Molecular Biology Reports

Volumn 40, Issue 5, 2013, Pages 3777-3782

  Lu, Yan ^a,e   Huang, Guo Liang ^a,e   Pu, Xing Xiang ^b   He, Yu Xiang ^c   Li, Bin Bin ^a,e   Liu, Xing Yan ^a,e   Dong, Zigang ^d   He, Zhiwei ^a,e  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b HUNAN CANCER HOSPITAL   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

^d UNIVERSITY OF MINNESOTA   (United States)

^e Key Laboratory for Medical Molecular Diagnostics of Guangdong Province   (China)

Author keywords

Nasopharyngeal carcinoma; PIN1; Polymorphism; Promoter; Risk

Indexed keywords

CYTOSINE; GUANINE; PEPTIDYLPROLYL ISOMERASE PIN1; THYMINE;

ADULT; ARTICLE; CARCINOGENESIS; CHINESE; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HETEROZYGOTE; HISTOPATHOLOGY; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CARCINOMA; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHINA; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; NEOPLASM STAGING; PEPTIDYLPROLYL ISOMERASE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RISK;

EID: 84878402377     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2454-6     Document Type: Article

References (35)

1. Lu KP, Zhou XZ (2007) The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease. Nat Rev Mol Cell Biol 8(11):904-916
2. Bao L, Kimzey A, Sauter G, Sowadski JM, Lu KP, Wang DG (2004) Prevalent overexpression of prolyl isomerase Pin1 in human cancers. Am J Pathol 164(5):1727-1737
3. Ayala G, Wang D, Wulf G, Frolov A, Li R, Sowadski J, Wheeler TM, Lu KP, Bao L (2003) The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer. Cancer Res 63(19):6244-6251
4. Fukuchi M, Fukai Y, Kimura H, Sohda M, Miyazaki T, Nakajima M, Masuda N, Tsukada K, Kato H, Kuwano H (2006) Prolyl isomerase Pin1 expression predicts prognosis in patients with esophageal squamous cell carcinoma and correlates with cyclin D1 expression. Int J Oncol 29(2):329-334
5. He J, Zhou F, Shao K, Hang J, Wang H, Rayburn E, Xiao ZX, Lee SW, Xue Q, Feng XL, Shi SS, Zhang CY, Zhang S (2007) Overexpression of Pin1 in non-small cell lung cancer (NSCLC) and its correlation with lymph node metastases. Lung Cancer 56(1):51-58
6. Chen SY, Wulf G, Zhou XZ, Rubin MA, Lu KP, Balk SP (2006) Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction. Mol Cell Biol 26(3):929-939
7. Li H, Wang S, Zhu T, Zhou J, Xu Q, Lu Y, Ma D (2006) Pin1 contributes to cervical tumorigenesis by regulating cyclin D1 expression. Oncol Rep 16(3):491-496
8. Pang R, Lee TK, Poon RT, Fan ST, Wong KB, Kwong YL, Tse E (2007) Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. Gastroenterology 132(3):1088-1103
9. Ryo A, Liou YC, Lu KP, Wulf G (2003) Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer. J Cell Sci 116(Pt 5):773-783
10. Xu GG, Etzkorn FA (2009) Pin1 as an anticancer drug target. Drug News Perspect 22(7):399-407
11. Segat L, Pontillo A, Annoni G, Trabattoni D, Vergani C, Clerici M, Arosio B, Crovella S (2007) PIN1 promoter polymorphisms are associated with Alzheimer's disease. Neurobiol Aging 28(1):69-74
12. Han CH, Lu J, Wei Q, Bondy ML, Brewster AM, Yu TK, Buchholz TA, Arun BK, Wang LE (2010) The functional promoter polymorphism (-842G>C) in the PIN1 gene is associated with decreased risk of breast cancer in non-hispanic white women 55 years and younger. Breast Cancer Res Treat 122(1):243-249
13. Lu J, Hu Z, Wei S, Wang LE, Liu Z, El-Naggar AK, Sturgis EM, Wei Q (2009) A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity. Carcinogenesis 30(10):1717-1721
14. Segat L, Milanese M, Crovella S (2007) Pin1 promoter polymorphisms in hepatocellular carcinoma patients. Gastroenterology 132(7):2618-2619 author reply 2619-2620
15. Lu J, Yang L, Zhao H, Liu B, Li Y, Wu H, Li Q, Zeng B, Wang Y, Ji W, Zhou Y (2011) The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in Southern and Eastern Chinese populations. Hum Mutat 32(11):1299-1308
16. Tao Q, Chan AT (2007) Nasopharyngeal carcinoma: molecular pathogenesis and therapeutic developments. Expert Rev Mol Med 9(12):1-24
17. Cho WC (2007) Nasopharyngeal carcinoma: molecular biomarker discovery and progress. Mol Cancer 6:1
18. Catarino RJ, Breda E, Coelho V, Pinto D, Sousa H, Lopes C, Medeiros R (2006) Association of the A870G cyclin D1 gene polymorphism with genetic susceptibility to nasopharyngeal carcinoma. Head Neck 28(7):603-608
19. Liou YC, Ryo A, Huang HK, Lu PJ, Bronson R, Fujimori F, Uchida T, Hunter T, Lu KP (2002) Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes. Proc Natl Acad Sci U S A 99(3):1335-1340
20. Wulf GM, Ryo A, Wulf GG, Lee SW, Niu T, Petkova V, Lu KP (2001) Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. EMBO J 20(13):3459-3472
21. Miyashita H, Mori S, Motegi K, Fukumoto M, Uchida T (2003) Pin1 is overexpressed in oral squamous cell carcinoma and its levels correlate with cyclin D1 overexpression. Oncol Rep 10(2):455-461
22. Miyashita H, Uchida T, Mori S, Echigo S, Motegi K (2003) Expression status of Pin1 and cyclins in oral squamous cell carcinoma: Pin1 correlates with Cyclin D1 mRNA expression and clinical significance of cyclins. Oncol Rep 10(4):1045-1048
23. Nakashima M, Meirmanov S, Naruke Y, Kondo H, Saenko V, Rogounovitch T, Shimizu-Yoshida Y, Takamura N, Namba H, Ito M, Abrosimov A, Lushnikov E, Roumiantsev P, Tsyb A, Yamashita S, Sekine I (2004) Cyclin D1 overexpression in thyroid tumours from a radio-contaminated area and its correlation with Pin1 and aberrant beta-catenin expression. J Pathol 202(4):446-455
24. Zhou CX, Gao Y (2006) Aberrant expression of beta-catenin, Pin1 and cylin D1 in salivary adenoid cystic carcinoma: relation to tumor proliferation and metastasis. Oncol Rep 16(3):505-511
25. Naidu R, Har YC, Taib NA (2011) Analysis of peptidyl-propyl-cis/trans isomerase 1 (PIN1) gene -842 (G>C) and -667 (T>C) polymorphic variants in relation to breast cancer risk and clinico-pathological parameters. Scand J Clin Lab Invest 71(6):500-506
26. Yeh ES, Lew BO, Means AR (2006) The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability. J Biol Chem 281(1):241-251
27. Ryo A, Nakamura M, Wulf G, Liou YC, Lu KP (2001) Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC. Nat Cell Biol 3(9):793-801. doi: 10.1038/ncb0901-793
28. Yeh E, Cunningham M, Arnold H, Chasse D, Monteith T, Ivaldi G, Hahn WC, Stukenberg PT, Shenolikar S, Uchida T, Counter CM, Nevins JR, Means AR, Sears R (2004) A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol 6(4):308-318
29. Zacchi P, Gostissa M, Uchida T, Salvagno C, Avolio F, Volinia S, Ronai Z, Blandino G, Schneider C, Del Sal G (2002) The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature 419(6909):853-857
30. Zheng H, You H, Zhou XZ, Murray SA, Uchida T, Wulf G, Gu L, Tang X, Lu KP, Xiao ZX (2002) The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature 419(6909):849-853
31. Mantovani F, Piazza S, Gostissa M, Strano S, Zacchi P, Mantovani R, Blandino G, Del Sal G (2004) Pin1 links the activities of c-Abl and p300 in regulating p73 function. Mol Cell 14(5):625-636
32. Dougherty MK, Muller J, Ritt DA, Zhou M, Zhou XZ, Copeland TD, Conrads TP, Veenstra TD, Lu KP, Morrison DK (2005) Regulation of Raf-1 by direct feedback phosphorylation. Mol Cell 17(2):215-224
33. Lam PB, Burga LN, Wu BP, Hofstatter EW, Lu KP, Wulf GM (2008) Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability. Mol Cancer 7:91. doi: 10.1186/1476-4598-7-91
34. Atkinson GP, Nozell SE, Harrison DK, Stonecypher MS, Chen D, Benveniste EN (2009) The prolyl isomerase Pin1 regulates the NF-kappaB signaling pathway and interleukin-8 expression in glioblastoma. Oncogene 28(42):3735-3745
35. Yeh ES, Means AR (2007) PIN1, the cell cycle and cancer. Nat Rev Cancer 7(5):381-388