Ontogenic expression of the amino acid transporter b0,+AT in suckling Huanjiang piglets: Effect of intra-uterine growth restriction

British Journal of Nutrition

Volumn 110, Issue 5, 2013, Pages 823-830

  Wang, Wence ^a,b   Blachier, Francois ^c   Fu, Dezhi ^b   Pan, Jie ^d   Yang, Huansheng ^b   Guo, Jieping ^b   Chu, Wuying ^e   Kong, Xiangfeng ^b   Yin, Yulong ^b  

^a SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c INRA Institut National de la Recherche Agronomique   (France)

^d HUNAN AGRICULTURAL UNIVERSITY   (China)

^e CHANGSHA UNIVERSITY   (China)

Author keywords

Amino acid transporters; Huanjiang mini piglets; Intra uterine growth restriction; Nutrition; Small intestine

Indexed keywords

AMINO ACID TRANSPORTER; AMINO ACID TRANSPORTER B0,+AT SUBUNIT; ARGININE; CYSTEINE; LYSINE; MESSENGER RNA; RNA 18S; UNCLASSIFIED DRUG;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DISEASE ASSOCIATION; GENE EXPRESSION; INTRAUTERINE GROWTH RETARDATION; JEJUNUM; LIMIT OF DETECTION; NONHUMAN; ONTOGENY; PIGLET; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SUCKLING; WEIGHT REDUCTION; WESTERN BLOTTING;

AMINO ACID TRANSPORT SYSTEMS; ANIMALS; ANIMALS, SUCKLING; FETAL GROWTH RETARDATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; RNA, MESSENGER; SWINE;

EID: 84878397854     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512005843     Document Type: Article

References (58)

1. Wu G, Bazer WF, Wallace MJ, et al. (2006) Intrauterine growth retardation: Implications for the animal sciences. J Anim Sci 84, 2316-2337.
2. McMillen IC & Robinson JS (2005) Developmental origins of the metabolic syndrome: Prediction, plasticity, and programming. Physiol Rev 85, 571-633.
3. Baserga M, Bertolotto C, Maclennan NK, et al. (2004) Uteroplacental insufficiency decreases small intestine growth and alters apoptotic homeostasis in term intrauterine growth retarded rats. Early Hum Dev 79, 93-105.
4. Xu RJ, Mellor DJ, Birtles MJ, et al. (1994) Impact of intrauterine growth retardation on the gastrointestinal tract and the pancreas in newborn pigs. J Pediatr Gastroenterol Nutr 18, 231-240.
5. D'Inca R, Kloareg M, Gras-Le Guen C, et al. (2010) Intrauterine growth restriction modifies the developmental pattern of intestinal structure, transcriptomic profile, and bacterial colonization in neonatal pigs. J Nutr 140, 925-931.
6. Blachier F, Boutry C, Bos C, et al. (2009) Metabolism and functions of L-glutamate in the epithelial cells of the small and large intestines. Am J Clin Nutr 90, 814S-821S.
7. Coloso RM & Stipanuk MH (1989) Metabolism of cyst(e)ine in rat enterocytes. J Nutr 119, 1914-1924.
8. Yin YL, Huang RL, Li TJ, et al. (2010) Amino acid metabolism in the portal-drained viscera of young pigs: Effects of dietary supplementation with chitosan and pea hull. Amino Acids 39, 1581-1587.
9. Shoveller AK, Stoll B, Ball RO, et al. (2005) Nutritional and functional importance of intestinal sulfur amino acid metabolism. J Nutr 35, 1609-1612.
10. Blachier F, M'Rabet-Touil H, Posho L, et al. (1993) Intestinal arginine metabolism during development. Evidence for de novo synthesis of L-arginine in newborn pig enterocytes. Eur J Biochem 216, 109-117.
11. Chen LX, Yin YL, Jobgen WS, et al. (2007) In vitro oxidation of essential amino acids by jejunal mucosal cells of growing pigs. Livest Sci 109, 19-23.
12. Chen LX, Li P, Wang JJ, et al. (2009) Catabolism of nutritionally essential amino acids in developing porcine enterocytes. Amino Acids 37, 143-152.
13. Feliubadaló L, Font M, Purroy J, et al. (1999) Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (b0+AT) of rBAT. Nat Genet 23, 52-57.
14. Munck BG (1980) Lysine transport across the small intestine. Stimulating and inhibitory effects of neutral amino acids. J Membr Biol 53, 45-53.
15. Dello Strologo L, Pras E, Pontesilli C, et al. (2002) Comparison between SLC3A1 and SLC7A9 cystinuria patients and carriers: A need for a new classification. J Am Soc Nephrol 13, 2547-2553.
16. Dave MH, Schulz N, Zecevic M, et al. (2004) Expression of heteromeric amino acid transporters along the murine intestine. Am J Physiol 258, 597-610.
17. Verrey F, Closs EI, Wagner CA, et al. (2004) CATs and HATs: The SLC7 family of amino acid transporters. Pflü g Arch Eur J Physiol 447, 532-542.
18. Reig N, Chillarón J, Bartoccioni P, et al. (2002) The light subunit of system b0+ is fully functional in the absence of the heavy subunit. EMBO J 18, 4906-4914.
19. Flynn NE, Meininger CJ, Haynes TE, et al. (2002) The metabolic basis of arginine nutrition and pharmacotherapy. Biomed Pharmacother 56, 427-438.
20. Wu G, Fang YZ, Yang S, et al. (2004) Glutathione metabolism and its implications for health. J Nutr 134, 489-492.
21. Zhao DS (2008) Characteristic and feeding management of fragrant pigs. Livest Poult Husb 3, 16-17.
22. Yang HS, Fu DZ, Shao H, et al. (2012) Impacts of birth weight on plasma, liver and skeletal muscle neutral amino acid profiles and intestinal amino acid transporters in suckling Huanjiang mini-piglets. PLoS One 7, e50921.
23. Yang HS, Li FN, Yin YL, et al. (2013) Soy isoflavones modulate adipokines and myokines to regulate lipid metabolism in adipose tissue, skeletal muscle and liver of male Huanjiang mini-pigs. Mol Cell Endocrinol 365, 44-51.
24. He QH, Ren PP, Kong XF, et al. (2012) Comparison of serum metabolite compositions between obese and lean growing pigs. J Nutr Biochem 23, 133-139.
25. Li FN, Li LL, Yang HS, et al. (2011) Regulation of soy isoflavones on weight gain and fat percentage: Evaluation in a Chinese Guangxi minipig model. Animal 5, 1903-1908.
26. Yang HS, Li FN, Kong XF, et al. (2012) Molecular cloning, tissue distribution and ontogenetic expression of Xiang pig chemerin and its involvement in regulating energy metabolism through Akt and ERK1/2 signaling pathways. Mol Biol Rep 39, 1887-1894.
27. Zhang M, Jing RB & Cui HB (1996) The investigation of growth development, reproductive characteristics and experimental animalization in fragrant pigs. Swine Prod 2, 30-32.
28. Yu PC, Hua XG, Xu JX, et al. (2002) Measurements on growth and development and fattening performance of Xiang pigs. J Shanghai Jiaotong Univ (Agric Sci) 20, 228-231.
29. Zhang Y, Liu PQ & Luo AQ (2008) Determination of fatty acids and nutritional evaluation in Scent pig muscle. Swine Prod 6, 39-40.
30. Reeds PJ, Burrin DG, Stoll B, et al. (2000) Intestinal glutamate metabolism. J Nutr 130, 978S-982S.
31. Luo G, Zhang L, Liu LS, et al. (2004) The applied research prospects of laboratory mini-pig in China. Lab Anim Sci Manage 2, 37-38.
32. He QH, Ren PP, Kong XF, et al. (2011) Intrauterine growth restriction alters the metabonome of the serum and jejunum in piglets. Mol Bio Syst 7, 2147-2155.
33. Liu ZQ, Geng MM, Shu XG, et al. (2012) Dietary NCG supplementation enhances the expression of N-acetylglutamate synthase in intestine of weaning pig. J Food Agric Environ 10, 408-412.
34. Tang ZR, Yin LY, Nyachoti CM, et al. (2005) Effect of dietary supplementation of chitosan and galacto-mannanoligosaccharide on serum parameters and the insulin like growth factor-I mRNA expression in early-weaned piglets. Domes Anim Endocrinol 28, 430-441.
35. Yao K, Yin YL, Chu WY, et al. (2008) Dietary arginine supplementation increases mTOR signaling activity in skeletal muscle of neonatal pigs. J Nutr 138, 867-872.
36. Yin YL, Baidoo SK, Schulze H, et al. (2001) Effect of supplementing diets containing hulless barley varieties having different levels of non-starch polysaccharides with b-glucanase and xylanase on the physiological status of gastrointestinal tract and nutrient digestibility of weaned pigs. Livest Prod Sci 71, 97-107.
37. Kong XF, Yin FG, He QH, et al. (2009) Acanthopanax senticosus extract as a dietary additive enhances the apparent ileal digestibility of amino acids in weaned piglets. Livest Sci 123, 261-267.
38. Wang WC, Gu WT, Tang XF, et al. (2009) Molecular cloning, tissue distribution and ontogenetic expression of the amino acid transporter b0+ cDNA in the small intestine of Tibetan suckling piglets. Compar Biochem Physiol Part B 154, 157-164.
39. Muller PY, Janoviak H, Miserez AR, et al. (2002) Processing of gene expression data generated by quantitative real-time QPCR. Biotechniques 32, 1372-1374, 1376, 1378-1379.
40. Wang WC, Shi CY, Zhang JS, et al. (2009) Molecular cloning, distribution and ontogenetic expression of the oligopeptide transporter PepT1 mRNA in Tibetan suckling piglets. Amino Acids 37, 593-601.
41. Wolter BF & Ellis M (2001) The effect of weaning weight and rate of growth immediately after weaning on subsequent pig growth performance and carcass characteristics. Can J Anim Sci 81, 363-369.
42. Azain MJ, Tomkins T, Sowinski JS, et al. (1996) Effect of supplemental pig milk replacer on litter performance: Seasonal variation in response. J Anim Sci 74, 2195-2202.
43. King RH, Boyce JM & Dunshea FR (1998) Effect of supplemental nutrients on the growth performance of sucking pigs. Aust J Agric Res 49, 883-887.
44. Wolter BF, Ellis M, Corrigan BP, et al. (2002) The effect of birth weight and feeding of supplemental milk replacer to piglets during lactation on preweaning and postweaning growth performance and carcass characteristics. J Anim Sci 80, 301-308.
45. Campbell RG & Dunkin AC (1982) The effect of birth weight on the estimated milk intake, growth and body composition of sow-reared piglets. Anim Prod 35, 193-197.
46. Xu D, Phillips JC & Schulten K (1996) Protein response to external electric fields: Relaxation, hysteresis, and echo. J Phys Chem 100, 12108-12121.
47. Blachier F, Guihot-Joubrel G, Vaugelade P, et al. (1999) Portal hyperglutamatemia after dietary supplementation with monosodium glutamate in pigs. Digestion 60, 349-357.
48. Bertolo RF, Pencharz PB & Ball RO (2000) Organ and plasma amino acid concentrations are profoundly different in piglets fed identical diets via gastric, central venous or portal venous routes. J Nutr 130, 1261-1266.
49. Wang J, Chen L, Li D, et al. (2008) Intrauterine growth restriction affects the proteomes of the small intestine, liver, and skeletal muscle in newborn pigs. J Nutr 138, 60-66.
50. Bröer S (2008) Apical transporters for neutral amino acids: Physiology and pathophysiology. Physiol (Bethesda) 23, 95-103.
51. Blomberg LA, Schreier LL, David Guthrie H, et al. (2010) The effect of intrauterine growth retardation on the expression of developmental factors in porcine placenta subsequent to the initiation of placentation. Placenta 31, 549-552.
52. Thornbury JC, Sibbons PD, van Velzen D, et al. (1993) Histological investigations into the relationship between low birth weight and spontaneous bowel damage in the neonatal piglet. Pediatr Pathol 13, 59-69.
53. Regnault TRH, Friedman JE, Wilkening RB, et al. (2005) Fetoplacental transport and utilization of amino acids in IUGR - a review. Placenta 26, Suppl. A, S52-S62.
54. Wang X, Wu W, Lin G, et al. (2010) Temporal proteomic analysis reveals continuous impairment of intestinal development in neonatal piglets with intrauterine growth restriction. J Proteome Res 9, 924-935.
55. Bisceglia L, Fischetti L & Bonis PD (2010) Large rearrangements detected by MLPA, point mutations, and survey of the frequency of mutations within the SLC3A1 and SLC7A9 genes in a cohort of 172 cystinuric Italian patients. Mol Genet Metab 99, 42-52.
56. Ercolani M, Sahota A, Schuler C, et al. (2010) Bladder outlet obstruction in male cystinuria mice. Int Urol Nephrol 42, 57-63.
57. Bröer S. (2008) Amino acid transport across mammalian intestinal and renal epithelia. Physiol Rev 88, 249-286.
58. Sperandeo MP, Annunziata P, Bozzato A, et al. (2007) Slc7a7 disruption causes fetal growth retardation by downregulating Igf1 in the mouse model of lysinuric protein intolerance. Am J Physiol Cell Physiol 293, 191-198.