Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

Blood

Volumn 121, Issue 13, 2013, Pages 2440-2451

  Malinge, Sébastien ^a   Thiollier, Clarisse ^b   Chlon, Timothy M ^a   Doré, Louis C ^a   Diebold, Lauren ^a   Bluteau, Olivier ^c   Mabialah, Vinciane ^b   Vainchenker, William ^c   Dessen, Philippe ^b   Winandy, Susan ^d   Mercher, Thomas ^b   Crispino, John D ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c INSERM   (France)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IKAROS TRANSCRIPTION FACTOR; NOTCH RECEPTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR IKAROS 1; UNCLASSIFIED DRUG; GATA1 PROTEIN, MOUSE; ZFPN1A1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL EXPANSION; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; ERYTHROID CELL; FLOW CYTOMETRY; GENE CONTROL; IN VIVO STUDY; INTRACELLULAR SIGNALING; MEGAKARYOBLAST; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; ANIMAL; ANIMAL EMBRYO; BIOLOGICAL MODEL; CELL CULTURE; CELL PROLIFERATION; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; PROTEIN BINDING; SIGNAL TRANSDUCTION; THROMBOCYTOPOIESIS;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DOWN-REGULATION; EMBRYO, MAMMALIAN; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IKAROS TRANSCRIPTION FACTOR; MEGAKARYOCYTES; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PROTEIN BINDING; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; THROMBOPOIESIS;

MLCS; MLOWN;

EID: 84878393018     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-08-450627     Document Type: Article

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