The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment

Blood

Volumn 121, Issue 13, 2013, Pages 2474-2482

  Dorrance, Adrienne M ^a,b   De Vita, Serena ^a   Radu, Maria ^c   Reddy, Pavankumar N G ^a   McGuinness, Meaghan K ^a   Harris, Chad E ^a   Mathieu, Ronald ^a   Lane, Steven W ^a   Kosoff, Rachelle ^c   Milsom, Michael D ^a   Chernoff, Jonathan ^c   Williams, David A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; P21 ACTIVATED KINASE; STEM CELL ANTIGEN 1; STEM CELL FACTOR RECEPTOR; RAC PROTEIN;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL HOMING; CELL MIGRATION; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CONTROLLED STUDY; ENGRAFTMENT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GRAFT FAILURE; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL MOTION; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; METABOLISM; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PHYSIOLOGY;

ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; P21-ACTIVATED KINASES; RAC GTP-BINDING PROTEINS;

MLCS; MLOWN;

EID: 84878380745     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-460709     Document Type: Article

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