Human adipose-derived mesenchymal stem cells can survive and integrate into the adult rat eye following xenotransplantation

Xenotransplantation

Volumn 20, Issue 3, 2013, Pages 165-176

  Haddad Mashadrizeh, Aliakbar ^a   Bahrami, Ahmad R ^a   Matin, Maryam M ^a   Edalatmanesh, Mohammad A ^b   Zomorodipour, Alireza ^c   Gardaneh, Mossa ^c   Farshchian, Moein ^a   Momeni Moghaddam, Madjid ^a  

^a FERDOWSI UNIVERSITY OF MASHHAD   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

^c NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

Author keywords

blood retina barrier; cell integration; cell migration; cell survival; stem cell therapy; Xenotransplantation

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD RETINA BARRIER; CELL ADHESION; CELL EXPANSION; CELL LABELING; CELL MIGRATION; CELL SURVIVAL; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; RAT; VITREOUS BODY; XENOTRANSPLANTATION;

BLOOD-RETINA BARRIER; CELL INTEGRATION; CELL MIGRATION; CELL SURVIVAL; STEM-CELL THERAPY; XENOTRANSPLANTATION;

ADIPOSE TISSUE; ANIMALS; BLINDNESS; BLOOD-RETINAL BARRIER; CELL DIFFERENTIATION; CELL SURVIVAL; EYE; GENE EXPRESSION; HETEROGRAFTS; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; OPHTHALMOLOGIC SURGICAL PROCEDURES; RATS; RATS, WISTAR; RETINAL DISEASES; TIME FACTORS; VITREOUS BODY;

EID: 84878334926     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/xen.12033     Document Type: Article

References (72)

1. Bi YY, Feng DF, Pan DC,. Stem/progenitor cells: a potential source of retina-specific cells for retinal repair. Neurosci Res 2009; 65: 215-221.
2. Jin ZB, Okamoto S, Mandai M, Takahashi M,. Induced pluripotent stem cells for retinal degenerative diseases: a new perspective on the challenges. J Genet 2009; 88: 417-424.
3. Lorenz B, Preising M, Stieger K,. Retinal blinding disorders and gene therapy-molecular and clinical aspects. Curr Gene Ther 2010; 10: 350-370.
4. Matthaei M, Zeitz O, Keseru M, et al. Progress in the development of vision prostheses. Ophthalmologica 2011; 225: 187-192.
5. Singh MS, Maclaren RE,. Stem cells as a therapeutic tool for the blind: biology and future prospects. Proc Biol Sci 2011; 278: 3009-3016.
6. Goureau O, Sahel JA,. Retinal stem cells: mechanism of differentiation and therapeutic application. Pathol Biol (Paris) 2006; 54: 64-71.
7. Wallace VA,. Stem cells: a source for neuron repair in retinal disease. Can J Ophthalmol 2007; 42: 442-446.
8. Corredor RG, Goldberg JL,. Electrical activity enhances neuronal survival and regeneration. J Neural Eng 2009; 6: 055001.
9. Ashtari M, Cyckowski LL, Monroe JF, et al. The human visual cortex responds to gene therapy-mediated recovery of retinal function. J Clin Invest 2011; 121: 2160-2168.
10. Bull ND, Martin KR,. Using stem cells to mend the retina in ocular disease. Regen Med 2009; 4: 855-864.
11. Tansley K,. The development of the rat eye in graft. J Exp Biol 1946; 22: 221-224.
12. Maclaren RE, Pearson RA, Macneil A, et al. Retinal repair by transplantation of photoreceptor precursors. Nature 2006; 444: 203-207.
13. Boulton M, Albon J,. Stem cells in the eye. Int J Biochem Cell Biol 2004; 36: 643-657.
14. Zhang X, Li GL,. Progress in treatment of retinitis pigmentosa by neurotrophic factors. Zhonghua Yan Ke Za Zhi 2009; 45: 855-859.
15. Lamba DA, Karl MO, Ware CB, Reh TA,. Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci USA 2006; 103: 12769-12774.
16. Lamba DA, Gust J, Reh TA,. Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in Crx-deficient mice. Cell Stem Cell 2009; 4: 73-79.
17. Strem BM, Hicok KC, Zhu M, et al. Multipotential differentiation of adipose tissue-derived stem cells. Keio J Med 2005; 54: 132-141.
18. Zuk PA, Zhu M, Ashjian P, et al. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002; 13: 4279-4295.
19. Rodriguez AM, Elabd C, Amri EZ, Ailhaud G, Dani C,. The human adipose tissue is a source of multipotent stem cells. Biochimie 2005; 87: 125-128.
20. Vieira NM, Brandalise V, Zucconi E, et al. Human multipotent adipose-derived stem cells restore dystrophin expression of Duchenne skeletal-muscle cells in vitro. Biol Cell 2008; 100: 231-241.
21. Sowa Y, Imura T, Numajiri T, Nishino K, Fushiki S,. Adipose-derived stem cells produce factors enhancing peripheral nerve regeneration: influence of age and anatomic site of origin. Stem Cells Dev 2012; 21: 1852-1862.
22. Gimble JM, Katz AJ, Bunnell BA,. Adipose-derived stem cells for regenerative medicine. Circ Res 2007; 100: 1249-1260.
23. Gimble J, Guilak F,. Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. Cytotherapy 2003; 5: 362-369.
24. Zufferey R, Dull T, Mandel RJ, et al. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 1998; 72: 9873-9880.
25. Gao J, Dennis JE, Muzic RF, Lundberg M, Caplan AI,. The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues Organs 2001; 169: 12-20.
26. Kraitchman DL, Tatsumi M, Gilson WD, et al. Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation 2005; 112: 1451-1461.
27. Ushiki T, Kizaka-Kondoh S, Ashihara E, et al. Noninvasive tracking of donor cell homing by near-infrared fluorescence imaging shortly after bone marrow transplantation. PLoS One 2010; 5: e11114.
28. Whelan JA, Russell NB, Whelan MA,. A method for the absolute quantification of cDNA using real-time PCR. J Immunol Methods 2003; 278: 261-269.
29. Schmittgen TD, Livak KJ,. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 2008; 3: 1101-1108.
30. Tyas DA, Simpson TI, Carr CB, et al. Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse. BMC Dev Biol 2006; 6: 21.
31. Diaczok D, Romero C, Zunich J, Marshall I, Radovick S,. A novel dominant negative mutation of OTX2 associated with combined pituitary hormone deficiency. J Clin Endocrinol Metab 2008; 93: 4351-4359.
32. Chen S, Wang QL, Nie Z, et al. Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes. Neuron 1997; 19: 1017-1030.
33. Mangan SH, van Campenhout A, Rush C, Golledge J,. Osteoprotegerin upregulates endothelial cell adhesion molecule response to tumor necrosis factor-alpha associated with induction of angiopoietin-2. Cardiovasc Res 2007; 76: 494-505.
34. Vossmerbaeumer U, Ohnesorge S, Kuehl S, et al. Retinal pigment epithelial phenotype induced in human adipose tissue-derived mesenchymal stromal cells. Cytotherapy 2009; 11: 177-188.
35. Joe AW, Gregory-Evans K,. Mesenchymal stem cells and potential applications in treating ocular disease. Curr Eye Res 2010; 35: 941-952.
36. Bexell D, Gunnarsson S, Tormin A, et al. Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas. Mol Ther 2009; 17: 183-190.
37. Cavarretta IT, Altanerova V, Matuskova M, Kucerova L, Culig Z, Altaner C,. Adipose tissue-derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth. Mol Ther 2010; 18: 223-231.
38. Altanerova V, Cihova M, Babic M, et al. Human adipose tissue-derived mesenchymal stem cells expressing yeast cytosinedeaminase:uracil phosphoribosyltransferase inhibit intracerebral rat glioblastoma. Int J Cancer 2012; 130: 2455-2463.
39. Castanheira P, Torquetti LT, Magalhas DR, Nehemy MB, Goes AM,. DAPI diffusion after intravitreal injection of mesenchymal stem cells in the injured retina of rats. Cell Transplant 2009; 18: 423-431.
40. Streilein JW, Stein-Streilein J,. Does innate immune privilege exist? J Leukoc Biol 2000; 67: 479-487.
41. Yu SH, Jang YJ, Lee ES, Hwang DY, Jeon CJ,. Transplantation of adipose derived stromal cells into the developing mouse eye. Acta Histochem Cytochem 2010; 43: 123-130.
42. Lee ES, Yu SH, Jang YJ, Hwang DY, Jeon CJ,. Transplantation of bone marrow-derived mesenchymal stem cells into the developing mouse eye. Acta Histochem Cytochem 2011; 44: 213-221.
43. Zhou HS, Liu DP, Liang CC,. Challenges and strategies: the immune responses in gene therapy. Med Res Rev 2004; 24: 748-761.
44. Bull ND, Limb GA, Martin KR,. Human Muller stem cell (MIO-M1) transplantation in a rat model of glaucoma: survival, differentiation, and integration. Invest Ophthalmol Vis Sci 2008; 49: 3449-3456.
45. Stout JT, Francis PJ,. Surgical approaches to gene and stem cell therapy for retinal disease. Hum Gene Ther 2011; 22: 531-535.
46. Wallace VA,. Concise review: making a retina-from the building blocks to clinical applications. Stem Cells 2011; 29: 412-417.
47. Lyon CJ, Evans CJ, Bill BR, Otsuka AJ, Aguilera RJ,. The C. elegans apoptotic nuclease NUC-1 is related in sequence and activity to mammalian DNase II. Gene 2000; 252: 147-154.
48. McIlroy D, Tanaka M, Sakahira H, et al. An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes. Genes Dev 2000; 14: 549-558.
49. Krieser RJ, White K,. Engulfment mechanism of apoptotic cells. Curr Opin Cell Biol 2002; 14: 734-738.
50. Goichberg P, Kalinkovich A, Borodovsky N, et al. cAMP-induced PKCzeta activation increases functional CXCR4 expression on human CD34+ hematopoietic progenitors. Blood 2006; 107: 870-879.
51. Nakashima M, Akamine A,. The application of tissue engineering to regeneration of pulp and dentin in endodontics. J Endod 2005; 31: 711-718.
52. Lue Y, Erkkila K, Liu PY, et al. Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure. Am J Pathol 2007; 170: 899-908.
53. Walter M, Liang S, Ghosh S, Hornsby PJ, Li R,. Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells. Oncogene 2009; 28: 2745-2755.
54. Kucerova L, Matuskova M, Hlubinova K, Altanerova V, Altaner C,. Tumor cell behaviour modulation by mesenchymal stromal cells. Mol Cancer 2010; 9: 129.
55. Crane IJ, Liversidge J,. Mechanisms of leukocyte migration across the blood-retina barrier. Semin Immunopathol 2008; 30: 165-177.
56. Zderic V, Vaezy S, Martin RW, Clark JI,. Ocular drug delivery using 20-kHz ultrasound. Ultrasound Med Biol 2002; 28: 823-829.
57. Runkle EA, Antonetti DA,. The blood-retinal barrier: structure and functional significance. Methods Mol Biol 2011; 686: 133-148.
58. Haurigot V, Villacampa P, Ribera A, et al. Increased intraocular insulin-like growth factor-I triggers blood-retinal barrier breakdown. J Biol Chem 2009; 284: 22961-22969.
59. Frey T, Antonetti DA,. Alterations to the blood-retinal barrier in diabetes: cytokines and reactive oxygen species. Antioxid Redox Signal 2011; 15: 1271-1284.
60. Funatsu H, Yamashita H, Nakamura S, et al. Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor are related to diabetic macular edema. Ophthalmology 2006; 113: 294-301.
61. Funatsu H, Yamashita H, Ikeda T, Mimura T, Eguchi S, Hori S,. Vitreous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edema. Ophthalmology 2003; 110: 1690-1696.
62. Funatsu H, Yamashita H, Noma H, et al. Aqueous humor levels of cytokines are related to vitreous levels and progression of diabetic retinopathy in diabetic patients. Graefes Arch Clin Exp Ophthalmol 2005; 243: 3-8.
63. Noma H, Funatsu H, Mimura T, Harino S, Hori S,. Aqueous humor levels of vasoactive molecules correlate with vitreous levels and macular edema in central retinal vein occlusion. Eur J Ophthalmol 2010; 20: 402-409.
64. Kilroy GE, Foster SJ, Wu X, et al. Cytokine profile of human adipose-derived stem cells: expression of angiogenic, hematopoietic, and pro-inflammatory factors. J Cell Physiol 2007; 212: 702-709.
65. Fischer C, Schneider M, Carmeliet P,. Principles and therapeutic implications of angiogenesis, vasculogenesis and arteriogenesis. Handb Exp Pharmacol 2006; 176 Pt 2: 157-212.
66. Lange CA, Bainbridge JW,. Oxygen sensing in retinal health and disease. Ophthalmologica 2012; 227: 115-131.
67. Kujawa MJ, Carrino DA, Caplan AI,. Substrate-bonded hyaluronic acid exhibits a size-dependent stimulation of chondrogenic differentiation of stage 24 limb mesenchymal cells in culture. Dev Biol 1986; 114: 519-528.
68. Li L, Xie T,. Stem cell niche: structure and function. Annu Rev Cell Dev Biol 2005; 21: 605-631.
69. Engler AJ, Sen S, Sweeney HL, Discher DE,. Matrix elasticity directs stem cell lineage specification. Cell 2006; 126: 677-689.
70. Bagherpoor AJ, Bahrami AR, Matin MM, Mahdavi-Shahri N, Edalatmanesh MA,. Investigating the effects of vitreous humour (crude extract) on growth and differentiation of rat mesenchymal stem cells (rMSCs) and human NTERA2 cells. Tsitol Genet 2010; 44: 15-21.
71. Chen XD,. Extracellular matrix provides an optimal niche for the maintenance and propagation of mesenchymal stem cells. Birth Defects Res C Embryo Today 2010; 90: 45-54.
72. Baudouin C, Fredj-Reygrobellet D, Brignole F, Negre F, Lapalus P, Gastaud P,. Growth factors in vitreous and subretinal fluid cells from patients with proliferative vitreoretinopathy. Ophthalmic Res 1993; 25: 52-59.