Tumor cell behaviour modulation by mesenchymal stromal cells

Molecular Cancer

Volumn 9, Issue , 2010, Pages

  Kucerova, Lucia ^a   Matuskova, Miroslava ^a   Hlubinova, Kristina ^a   Altanerova, Veronika ^a   Altaner, Cestmir ^a  

^a CANCER RESEARCH INSTITUTE   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; STROMAL CELL DERIVED FACTOR 1ALPHA; VASCULOTROPIN; CYTOKINE;

ADIPOSE TISSUE CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MELANOMA; MELANOMA CELL; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; TREATMENT RESPONSE; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT; XENOTRANSPLANTATION; ADIPOSE TISSUE; ANIMAL; BIOSYNTHESIS; CELL COMMUNICATION; COCULTURE; CYTOLOGY; DRUG SCREENING; EXPERIMENTAL MELANOMA; GENE EXPRESSION; GENE EXPRESSION PROFILING; METABOLISM; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADIPOSE TISSUE; ANIMALS; CELL COMMUNICATION; CELL LINE, TUMOR; COCULTURE TECHNIQUES; CYTOKINES; GENE EXPRESSION; GENE EXPRESSION PROFILING; GLIOBLASTOMA; HUMANS; MELANOMA, EXPERIMENTAL; MESENCHYMAL STEM CELLS; MICE; MICE, NUDE; RECEPTOR CROSS-TALK; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77952720888     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-9-129     Document Type: Article

References (49)

1. Giordano A, Galderisi U, Marino IR. From the laboratory bench to the patient's bedside: an update on clinical trials with mesenchymal stem cells. J Cell Physiol 2007, 211:27-35. 10.1002/jcp.20959, 17226788.
2. Le Blanc K, Ringdén O. Immunomodulation by mesenchymal stem cells and clinical experience. J Intern Med 2007, 262:509-25. 10.1111/j.1365-2796.2007.01844.x, 17949362.
3. Picinich SC, Mishra PJ, Mishra PJ, Glod J, Banerjee D. The therapeutic potential of mesenchymal stem cells. Cell- & tissue-based therapy. Expert Opin Biol Ther 2007, 7:965-73. 10.1517/14712598.7.7.965, 17665987.
4. Psaltis PJ, Zannettino AC, Worthley SG, Gronthos S. Concise review: mesenchymal stromal cells: potential for cardiovascular repair. Stem Cells 2008, 26:2201-10. 10.1634/stemcells.2008-0428, 18599808.
5. Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells in health and disease. Nat Rev Immunol 2008, 8:726-36. 10.1038/nri2395, 19172693.
6. Ning H, Yang F, Jiang M, Hu L, Feng K, Zhang J, Yu Z, Li B, Xu C, Li Y, Wang J, Hu J, Lou X, Chen H. The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study. Leukemia 2008, 22:593-9. 10.1038/sj.leu.2405090, 18185520.
7. Valtieri M, Sorrentino AJ. The mesenchymal stromal cell contribution to homeostasis. Cell Physiol 2008, 217:296-300.
8. Li H, Fan X, Houghton J. Tumor microenvironment: the role of the tumor stroma in cancer. J Cell Biochem 2007, 101:805-15. 10.1002/jcb.21159, 17226777.
9. Joyce JA, Pollard JW. Microenvironmental regulation of metastasis. Nat Rev Cancer 2009, 9:239-52. 10.1038/nrc2618, 19279573.
10. Hu M, Polyak K. Molecular characterisation of the tumor microenvironment in breast cancer. Eur J Cancer 2008, 44:2760-5. 10.1016/j.ejca.2008.09.038, 2729518, 19026532.
11. Hall B, Andreeff M, Marini F. The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles. Handb Exp Pharmacol 2007, 180:263-83. full_text, 17554513.
12. Roorda BD, ter Elst A, Kamps WA, de Bont ES. Bone marrow-derived cells and tumor growth: contribution of bone marrow-derived cells to tumor micro-environments with special focus on mesenchymal stem cells. Crit Rev Oncol Hematol 2009, 69:187-98. 10.1016/j.critrevonc.2008.06.004, 18675551.
13. Stagg J. Mesenchymal stem cells in cancer. Stem Cell Rev 2008, 4:119-24. 10.1007/s12015-008-9030-4, 18493880.
14. Mishra PJ, Mishra PJ, Humeniuk R, Medina DJ, Alexe G, Mesirov JP, Ganesan S, Glod JW, Banerjee D. Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells. Cancer Res 2008, 68:4331-9. 10.1158/0008-5472.CAN-08-0943, 2725025, 18519693.
15. Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, Richardson AL, Polyak K, Tubo R, Weinberg RA. Mesenchymal stem cells within tumor stroma promote breast cancer metastasis. Nature 2007, 449:557-63. 10.1038/nature06188, 17914389.
16. Ramasamy R, Lam EW, Soeiro I, Tisato V, Bonnet D, Dazzi F. Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth. Leukemia 2007, 21:304-10. 10.1038/sj.leu.2404489, 17170725.
17. Djouad F, Bony C, Apparailly F, Louis-Plence P, Jorgensen C, Noël D. Earlier onset of syngeneic tumors in the presence of mesenchymal stem cells. Transplantation 2006, 82:1060-6. 10.1097/01.tp.0000236098.13804.0b, 17060855.
18. Zhu W, Xu W, Jiang R, Qian H, Chen M, Hu J, Cao W, Han C, Chen Y. Mesenchymal stem cells derived from bone marrow favour tumor cell growth in vivo. Exp Mol Pathol 2006, 80:267-74. 10.1016/j.yexmp.2005.07.004, 16214129.
19. Yu JM, Jun ES, Bae YC, Jung JS. Mesenchymal stem cells derived from human adipose tissues favour tumor cell growth in vivo. Stem Cells Dev 2008, 17:463-73. 10.1089/scd.2007.0181, 18522494.
20. Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, Nguyen AT, Malide D, Combs CA, Hall G, Zhang J, Raffeld M, Rogers TB, Stetler-Stevenson W, Frank JA, Reitz M, Finkel T. Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med 2006, 203:1235-47. 10.1084/jem.20051921, 2121206, 16636132.
21. Qiao L, Xu Z, Zhao T, Zhao Z, Shi M, Zhao RC, Ye L, Zhang X. Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model. Cell Res 2008, 18:500-7. 10.1038/cr.2008.40, 18364678.
22. Qiao L, Xu ZL, Zhao TJ, Ye LH, Zhang XD. Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling. Cancer Lett 2008, 269:67-77. 10.1016/j.canlet.2008.04.032, 18571836.
23. Nakamura K, Ito Y, Kawano Y, Kurozumi K, Kobune M, Tsuda H, Bizen A, Honmou O, Niitsu Y, Hamada H. Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model. Gene Ther 2004, 11:1155-64. 10.1038/sj.gt.3302276, 15141157.
24. Kucerova L, Altanerova V, Matuskova M, Tyciakova S, Altaner C. Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy. Cancer Res 2007, 67:6304-13. 10.1158/0008-5472.CAN-06-4024, 17616689.
25. Kucerova L, Matuskova M, Pastorakova A, Tyciakova S, Jakubikova J, Bohovic R, Altanerova V, Alatner C. Cytosine deaminase expressing human mesenchymal stem cells mediated tumor regression in melanoma bearing mice. J Gene Med 2008, 10:1071-82. 10.1002/jgm.1239, 18671316.
26. Studeny M, Marini FC, Champlin RE, Zompetta C, Fidler IJ, Andreeff M. Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res 2002, 62:3603-8.
27. Kendall SE, Najbauer J, Johnston HF, Metz MZ, Li S, Bowers M, Garcia E, Kim SU, Barish ME, Aboody KS, Glackin CA. Neural stem cell targeting of glioma is dependent on phosphoinositide 3-kinase signalling. Stem Cells 2008, 26:1575-86. 10.1634/stemcells.2007-0887, 18339768.
28. Kögler G, Radke TF, Lefort A, Sensken S, Fischer J, Sorg RV, Wernet P. Cytokine production and hematopoiesis supporting activity of cord blood-derived unrestricted somatic stem cells. Exp Hematol 2005, 33:573-83. 10.1016/j.exphem.2005.01.012, 15850835.
29. Kilroy GE, Foster SJ, Wu X, Ruiz J, Sherwood S, Heifetz A, Ludlow JW, Stricker DM, Potiny S, Green P, Halvorsen YD, Cheatham B, Storms RW, Gimble JM. Cytokine profile of human adipose-derived stem cells: expression of angiogenic, hematopoietic, and pro-inflammatory factors. J Cell Physiol 2007, 212:702-9. 10.1002/jcp.21068, 17477371.
30. da Silva Meirelles L, Caplan AI, Nardi NB. In search of the in vivo identity of mesenchymal stem cells. Stem Cells 2008, 26:2287-99. 10.1634/stemcells.2007-1122, 18566331.
31. Ailles LE, Weissman IL. Cancer stem cells in solid tumors. Curr Opin Biotechnol 2007, 18:460-6. 10.1016/j.copbio.2007.10.007, 18023337.
32. Spaeth EL, Dembinski JL, Sasser AK, Watson K, Klopp A, Hall B, Andreeff M, Marini F. Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression. PLoS ONE 2009, 4:e4992. 10.1371/journal.pone.0004992, 2661372, 19352430.
33. Camps JL, Chang SM, Hsu TC, Freeman MR, Hong SJ, Zhau HE, von Eschenbach AC, Chung LW. Fibroblast-mediated acceleration of human epithelial tumor growth in vivo. Proc Natl Acad Sci USA 1990, 87:75-9. 10.1073/pnas.87.1.75, 53202, 2296606.
34. Noël A, De Pauw-Gillet MC, Purnell G, Nusgens B, Lapiere CM, Foidart JM. Enhancement of tumorigenicity of human breast adenocarcinoma cells in nude mice by matrigel and fibroblasts. Br J Cancer 1993, 68:909-15. 1968733, 8217606.
35. Studebaker AW, Storci G, Werbeck JL, Sansone P, Sasser AK, Tavolari S, Huang T, Chan MW, Marini FC, Rosol TJ, Bonafé M, Hall BM. Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner. Cancer Res 2008, 68:9087-95. 10.1158/0008-5472.CAN-08-0400, 18974155.
36. Naumov GN, Folkman J, Straume O. Tumor dormancy due to failure of angiogenesis: role of the microenvironment. Clin Exp Metastasis 2009, 26:51-60. 10.1007/s10585-008-9176-0, 18563595.
37. Kidd S, Caldwell L, Dietrich M, Samudio I, Spaeth EL, Watson K, Shi Y, Abbruzzese J, Konopleva M, Andreeff M, Marini FC. Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment. Cytotherapy 2010,
38. Hung SC, Deng WP, Yang WK, Liu RS, Lee CC, Su TC, Lin RJ, Yang DM, Chang CW, Chen WH, Wei HJ, Gelovani JG. Mesenchymal stem cell targeting of microscopic tumors and tumor stroma development monitored by noninvasive in vivo positron emission tomography imaging. Clin Cancer Res 2005, 11:7749-56. 10.1158/1078-0432.CCR-05-0876, 16278396.
39. Nakamizo A, Marini F, Amano T, Khan A, Studeny M, Gumin J, Chen J, Hentschel S, Vecil G, Dembinski J, Andreeff M, Lang FF. Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res 2005, 65:3307-18.
40. Schichor C, Birnbaum T, Etminan N, Schnell O, Grau S, Miebach S, Aboody K, Padovan C, Straube A, Tonn JC, Goldbrunner R. Vascular endothelial growth factor A contributes to glioma-induced migration of human marrow stromal cells (hMSC). Exp Neurol 2006, 199:301-10. 10.1016/j.expneurol.2005.11.027, 16574102.
41. Sun T, Sun BC, Ni CS, Zhao XL, Wang XH, Qie S, Zhang DF, Gu Q, Qi H, Zhao N. Pilot study on the interaction between B16 melanoma cell-line and bone-marrow derived mesenchymal stem cells. Cancer Lett 2008, 263:35-43. 10.1016/j.canlet.2007.12.015, 18234417.
42. Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005, 438:820-7. 10.1038/nature04186, 16341007.
43. Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature 2008, 454:436-44. 10.1038/nature07205, 18650914.
44. Lin G, Yang R, Banie L, Wang G, Ning H, Li LC, Lue TF, Lin CS. Effects of transplantation of adipose tissue-derived stem cells on prostate tumor. Prostate 2010,
45. Kioi M, Vogel H, Schultz G, Hoffman RM, Harsh GR, Brown JM. Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J Clin Invest 2010, 120:694-705. 2827954, 20179352.
46. Lazennec G, Richmond A. Chemokines and chemokine receptors: new insights into cancer-related inflammation. Trends Mol Med 2010, 16:133-44. 10.1016/j.molmed.2010.01.003, 20163989.
47. Enderlin M, Kleinmann EV, Struyf S, Buracchi C, Vecchi A, Kinscherf R, Kiessling F, Paschek S, Sozzani S, Rommelaere J, Cornelis JJ, Van Damme J, Dinsart C. TNF-alpha and the IFN-gamma-inducible protein 10 (IP-10/CXCL-10) delivered by parvoviral vectors act in synergy to induce antitumor effects in mouse glioblastoma. Cancer Gene Ther 2009, 16:149-60. 10.1038/cgt.2008.62, 18670452.
48. Lazennec G, Jorgensen C. Concise review: adult multipotent stromal cells and cancer: risk or benefit?. Stem Cells 2008, 26:1387-94. 10.1634/stemcells.2007-1006, 2572832, 18388305.
49. Matuskova M, Hlubinova K, Pastorakova A, Hunakova L, Altanerova V, Altaner C, Kucerova L. HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells. Cancer Lett 2010, 290:58-67. 10.1016/j.canlet.2009.08.028, 19765892.