1H NMR-based metabonomics study on the toxicity alleviation effect of other traditional Chinese medicines in Niuhuang Jiedu tablet to realgar (As2S2)

Journal of Ethnopharmacology

Volumn 148, Issue 1, 2013, Pages 88-98

  Xu, Wenfeng ^a   Wang, Haifeng ^a   Chen, Gang ^a   Li, Wen ^a   Xiang, Rongwu ^a   Pei, Yuehu ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Metabonomics; Niuhuang Jiedu Tablet; NMR spectroscopy; Reaglar (As2S2); Toxicity alleviation

Indexed keywords

AMINO ACID; BORNEOLUM SYNTHCTICUM EXTRACT; BOVIS CALCULUS ARTIFICIALIS EXTRACT; CHOLINE; GLYCYRRHIZAE RADIX EXTRACT; GYPSUM FIBROSUM EXTRACT; NIUHUANG JEIDU; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PLATYCODONIS RADIX EXTRACT; REALGAR EXTRACT; SCUTELLARIAE RADIX; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ARTICLE; BORNEOLUM SYNTHCTICUM; BOVIS CALCULUS ARTIFICIALIS; CHINESE MEDICINE; CLINICAL CHEMISTRY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG URINE LEVEL; ENERGY METABOLISM; GLYCYRRHIZA; GYPSUM FIBROSUM; HISTOPATHOLOGY; KIDNEY; LIVER; MALE; METABOLOMICS; NONHUMAN; PLATYCODONIS RADIX; PRESCRIPTION; PROTON NUCLEAR MAGNETIC RESONANCE; REALGAR;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ARSENICALS; ASPARTATE AMINOTRANSFERASES; BLOOD GLUCOSE; BLOOD UREA NITROGEN; DRUGS, CHINESE HERBAL; KIDNEY; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEDICINE, CHINESE TRADITIONAL; METABOLOMICS; RATS; RATS, WISTAR; SULFIDES; TABLETS; TRIGLYCERIDES;

RATTUS; RATTUS NORVEGICUS; SCUTELLARIA RADIX;

EID: 84878301789     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.03.073     Document Type: Article

References (52)

1. B.M. Beckwith-Hall, J.K. Nicholson, A.W. Nicholls, P.J. Foxall, J.C. Lindon, S.C. Connor, M. Abdi, J. Connelly, and E. Holmes Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins Chemical Research in Toxicology 11 1998 260 272
2. M.E. Bollard, N.R. Contel, T.M.D. Ebbels, L. Smith, O. Beckonert, G.H. Cantor, L. Lehman-McKeeman, E.C. Holmes, J.C. Lindon, J.K. Nicholson, and H.C. Keun NMR-Based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat Journal of Proteome Research 9 2010 59 69
3. 1H NMR Metabolomics 8 2012 1 11
4. L.L. Cheng, C. Wu, M.R. Smith, and R.G. Gonzalez Non-destructive quantitation of spermine in human prostate tissue samples using HRMAS 1H NMR spectroscopy at 9.4 T Febs Letters 494 2001 112 116
5. W.J. Dellow, S.T. Chambers, M. Lever, H. Lunt, and R.A. Robson Elevated glycine betaine excretion in diabetes mellitus patients is associated with proximal tubular dysfunction and hyperglycemia Diabetes Research and Clinical Practice 43 1999 91 99
6. W.B. Dunn, and D.I. Ellis Metabolomics: current analytical platforms and methodologies Trac-trends in Analytical Chemistry 24 2005 285 294
7. T. Gao Chinese Mineral Drugs and Their Application 1997 China Press of Traditional Chinese Medicine Beijing
8. K.P. Gartland, F.W. Bonner, and J.K. Nicholson Investigations into the biochemical effects of region-specific nephrotoxins Molecular Pharmacology 35 1989 242 250
9. 1H NMR-based metabolic profiling of naproxen-induced toxicity in rats Toxicology Letters 200 2011 1 7
10. B.B. Kahn, T. Alquier, D. Carling, and D.G. Hardie AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism Cell Metabolism 1 2005 15 25
11. S.C. Kim, S.H. Byun, C.H. Yang, C.Y. Kim, J.W. Kim, and S.G. Kim Cytoprotective effects of Glycyrrhizae radix extract and its active component liquiritigenin against cadmium-induced toxicity (effects on bad translocation and cytochrome c-mediated PARP cleavage) Toxicology 197 2004 239 251
12. S.E. Knowles, I.G. Jarrett, O.H. Filsell, and F.J. Ballard Production and utilization of acetate in mammals The Biochemical Journal 142 1974 401 411
13. I. Koch, S. Steven, V.W.M. Lai, A. Owen, K.J. Reimer, and W.R. Cullen Bioaccessibility and excretion of arsenic in Niu Huang Jie Du Pian pills Toxicology and Applied Pharmacology 222 2007 357 364
14. H.A. Krebs Rate control of the tricarboxylic acid cycle Advances in Enzyme Regulation 8 1970 335 353
15. Y.-M. Lao, J.-G. Jiang, and L. Yan Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine British Journal of Pharmacology 157 2009 1128 1141
16. K.J. Lee, and H.G. Jeong Protective effect of Platycodi radix on carbon tetrachloride-induced hepatotoxicity Food and Chemical Toxicology 40 2002 517 525
17. L. Li, B. Sun, Q. Zhang, J. Fang, K. Ma, Y. Li, H. Chen, F. Dong, Y. Gao, F. Li, and X. Yan Metabonomic study on the toxicity of Hei-Shun-Pian, the processed lateral root of Aconitum carmichaelii Debx. (Ranunculaceae) Journal of Ethnopharmacology 116 2008 561 568
18. Z.-Y. Li, H.-J. Zhi, S.-Y. Xue, H.-F. Sun, F.-S. Zhang, J.-P. Jia, J. Xing, L.-Z. Zhang, and X.-M. Qin Metabolomic profiling of the flower bud and rachis of Tussilago farfara with antitussive and expectorant effects on mice Journal of Ethnopharmacology 140 2012 83 90
19. J.C. Lindon, J.K. Nicholson, and J.R. Everett NMR spectroscopy of biofluids Annual Reports on Nmr Spectroscopy 38 1999 1 88
20. P. Liu, S. Liu, D. Tian, and P. Wang The applications and obstacles of metabonomics in traditional chinese medicine Evidence-Based Complementary and Alternative Medicine 2012 2012 1 4
21. 1H NMR spectroscopy Journal Of Pharmaceutical and Biomedical Analysis 52 2010 136 141
22. C. Lu, Y. Wang, Z. Sheng, G. Liu, Z. Fu, J. Zhao, J. Zhao, X. Yan, B. Zhu, and S. Peng NMR-based metabonomic analysis of the hepatotoxicity induced by combined exposure to PCBs and TCDD in rats Toxicology and Applied Pharmacology 248 2010 178 184
23. C. Marty-Teysset, C. Posthuma, J.S. Lolkema, P. Schmitt, C. Divies, and W.N. Konings Proton motive force generation by citrolactic fermentation in Leuconostoc mesenteroides Journal of Bacteriology 178 1996 2178 2185
24. J.D. McGarry, and D.W. Foster Regulation of hepatic fatty acid oxidation and ketone body production Annual Review of Biochemistry 49 1980 395 420
25. K. Morgenthal, W. Weckwerth, and R. Steuer Metabolomic networks in plants: transitions from pattern recognition to biological interpretation Biosystems 83 2006 108 117
26. D. Morvan, and A. Demidem Metabolomics by proton nuclear magnetic resonance spectroscopy of the response to chloroethylnitrosourea reveals drug efficacy and tumor adaptive metabolic pathways Cancer Research 67 2007 2150 2159
27. J.K. Nicholson, J. Connelly, J.C. Lindon, and E. Holmes Metabonomics: a platform for studying drug toxicity and gene function Nature Reviews Drug Discovery 1 2002 153 161
28. J.K. Nicholson, J.C. Lindon, and E. Holmes 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data Xenobiotica; The Fate of foreign Compounds in Biological Systems 29 1999 1181 1189
29. J.K. Nicholson, and I.D. Wilson Understanding 'global' systems biology: metabonomics and the continuum of metabolism Nature Reviews Drug Discovery 2 2003 668 676
30. A.N. Phipps, J. Stewart, B. Wright, and I.D. Wilson Effect of diet on the urinary excretion of hippuric acid and other dietary-derived aromatics in rat. A complex interaction between diet, gut microflora and substrate specificity Xenobiotica; The Fate of Foreign Compounds in Biological Systems 28 1998 527 537
31. X.-L. Piao, E.J. Cho, and M.H. Jang Cytoprotective effect of baicalein against peroxynitrite-induced toxicity in LLC-PK1 cells Food And Chemical Toxicology 46 2008 1576 1581
32. E.M. Shin, H.Y. Zhou, L.Y. Guo, J.A. Kim, S.H. Lee, I. Merfort, S.S. Kang, H.S. Kim, S. Kim, and Y.S. Kim Anti-inflammatory effects of glycyrol isolated from Glycyrrhiza uralensis in LPS-stimulated RAW264.7 macrophages International Immunopharmacology 8 2008 1524 1532
33. J.L. Smith, J.S. Wishnok, and W.M. Deen Metabolism and excretion of methylamines in rats Toxicology and Applied Pharmacology 125 1994 296 308
34. C.L. Sprague, L.A. Phillips, K.M. Young, and A.A. Elfarra Species and tissue differences in the toxicity of 3-butene-1,2-diol in male Sprague-Dawley rats and B6C3F1 mice Toxicological Sciences 80 2004 3 13
35. H. Sun, Q.-M. Che, X. Zhao, and X.-P. Pu Antifibrotic effects of chronic baicalein administration in a CCl4 liver fibrosis model in rats European Journal Of Pharmacology 631 2010 53 60
36. G. Tan, W. Liao, X. Dong, G. Yang, Z. Zhu, W. Li, Y. Chai, and Z. Lou Metabonomic profiles delineate the effect of traditional chinese medicine sini decoction on myocardial infarction in rats PloS one 7 2012 e34157
37. 1H NMR-based metabonomics study of the urinary biochemical changes in Kansui treated rat Journal Of Ethnopharmacology 141 2012 134 142
38. J. Trygg, E. Holmes, and T. Lundstedt Chemometrics in metabonomics Journal of Proteome Research 6 2007 469 479
39. M. Wang, R. Lamers, H. Korthout, J.H.J. van Nesselrooij, R.F. Witkamp, R. van der Heijden, P.J. Voshol, L.M. Havekes, R. Verpoorte, and J. van der Greef Metabolomics in the context of systems biology: Bridging traditional Chinese medicine and molecular pharmacology Phytotherapy Research 19 2005 173 182
40. C.J. Waterfield, J.A. Turton, M.D. Scales, and J.A. Timbrell Investigations into the effects of various hepatotoxic compounds on urinary and liver taurine levels in rats Archives of Toxicology 67 1993 244 254
41. L. Wei, P. Liao, H. Wu, X. Li, F. Pei, W. Li, and Y. Wu Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum Toxicology and Applied Pharmacology 227 2008 417 429
42. L. Wei, P. Liao, H. Wu, X. Li, F. Pei, W. Li, and Y. Wu Metabolic profiling studies on the toxicological effects of realgar in rats by 1H NMR spectroscopy Toxicology and Applied Pharmacology 234 2009 314 325
43. M. Wyss, and R. Kaddurah-Daouk Creatine and creatinine metabolism Physiological Reviews 80 2000 1107 1213
44. B. Xie, T. Gong, R. Gao, J. Liu, J. Zuo, X. Wang, and Z. Zhang Development of rat urinary HPLC-UV profiling for metabonomic study on Liuwei Dihuang Pills Journal of Pharmaceutical and Biomedical Analysis 49 2009 492 497
45. H.-R. Xiong, J. Luo, W. Hou, H. Xiao, and Z.-Q. Yang The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo Journal Of Ethnopharmacology 133 2011 718 723
46. L. Xue, Y. Wang, L. Liu, L. Zhao, T. Han, Q. Zhang, and L. Qin A 1HNMR-based metabonomics study of postmenopausal osteoporosis and intervention effects of er-xian decoction in ovariectomized rats International Journal of Molecular Sciences 12 2011 7635 7651
47. H.Q. Ye, L. Gan, X.L. Yang, and H.B. Xu Membrane-associated cytotoxicity induced by realgar in promyelocytic leukemia HL-60 cells Journal Of Ethnopharmacology 103 2006 366 371
48. T. Yokoyama, S. Banta, F. Berthiaume, D. Nagrath, R.G. Tompkins, and M.L. Yarmush Evolution of intrahepatic carbon, nitrogen, and energy metabolism in a d-galactosamine-induced rat liver failure model Metabolic Engineering 7 2005 88 103
49. S.H. Zeisel Dietary choline: biochemistry, physiology, and pharmacology Annual Review Of Nutrition 1 1981 95 121
50. S.H. Zeisel, J.S. Wishnok, and J.K. Blusztajn Formation of methylamines from ingested choline and lecithin The Journal of pharmacology and experimental therapeutics 225 1983 320 324
51. L. Zhao, H. Gao, Y. Zhao, and D. Lin Metabonomic analysis of the therapeutic effect of Zhibai Dihuang Pill in treatment of streptozotocin-induced diabetic nephropathy Journal Of Ethnopharmacology 142 2012 647 656
52. Y. Zhou, L. Lu, Z. Li, X. Gao, J. Tian, L. Zhang, B. Wu, and X. Qin Antidepressant-like effects of the fractions of Xiaoyaosan on rat model of chronic unpredictable mild stress Journal Of Ethnopharmacology 137 2011 236 244