Macrophage phenotype and remodeling outcomes in response to biologic scaffolds with and without a cellular component

Biomaterials

Volumn 30, Issue 8, 2009, Pages 1482-1491

  Brown, Bryan N ^a,b   Valentin, Jolene E ^a,b   Stewart Akers, Ann M ^b,c   McCabe, George P ^d   Badylak, Stephen F ^a,b,c  

^a University of Pittsburgh   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^d PURDUE UNIVERSITY   (United States)

Author keywords

Biocompatibility; ECM (extracellular matrix); Macrophage; Monocyte; Wound healing

Indexed keywords

BODY WALLS; CELLULAR COMPONENTS; CELLULAR MATERIALS; CONNECTIVE TISSUES; CYTOKINE; ECM (EXTRACELLULAR MATRIX); EFFECTOR MOLECULES; EXTRACELLULAR MATRIXES; HOST RESPONSES; HOST TISSUES; MONOCYTE; PCR METHODS; RECEPTOR EXPRESSIONS; URINARY BLADDERS; WOUND HEALING;

BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; BODY FLUIDS; ELECTRIC DISCHARGE MACHINING; MUSCULOSKELETAL SYSTEM; SCAFFOLDS; TISSUE;

MACROPHAGES;

ARGINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; TISSUE SCAFFOLD;

ABDOMINAL WALL DEFECT; ABDOMINAL WALL MUSCULATURE; ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOGRAFT; BLADDER; CELL INFILTRATION; CELL POLARITY; CELL POPULATION; CONNECTIVE TISSUE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNE RESPONSE; MACROPHAGE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; SCAR FORMATION; SWINE; TISSUE ENGINEERING; TISSUE REACTION; TISSUE TRANSPLANTATION; XENOGRAFT;

ANIMALS; CELL NUCLEUS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INDOLES; MACROPHAGES; MUSCLE, SKELETAL; PHENOTYPE; PROSTHESIS IMPLANTATION; RATS; RATS, SPRAGUE-DAWLEY; SUS SCROFA; TISSUE SCAFFOLDS; TRANSPLANTATION, AUTOLOGOUS; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HOMOLOGOUS;

RATTUS; SUIDAE;

EID: 58249093204     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.11.040     Document Type: Article

References (36)

1. Bissell M.J., Hall H.G., and Parry G. How does the extracellular matrix direct gene expression?. J Theor Bio 99 1 (1982) 31-68
2. Boudreau N., Myers C., and Bissell M.J. From laminin to lamin: regulation of tissue-specific gene expression by the ECM. Trends Cell Biol 5 1 (1995) 1-4
3. Ingber D. Extracellular matrix and cell shape: potential control points for inhibition of angiogenesis. J Cell Biochem 47 3 (1991) 236-241
4. Badylak S.F. The extracellular matrix as a biologic scaffold material. Biomaterials 28 25 (2007) 3587-3593
5. Badylak S.F. Xenogeneic extracellular matrix as a scaffold for tissue reconstruction. Transpl Immunol 12 3-4 (2004) 367-377
6. Badylak S., Meurling S., Chen M., Spievack A., and Simmons-Byrd A. Resorbable bioscaffold for esophageal repair in a dog model. J Pediatr Surg 35 7 (2000) 1097-1103
7. Badylak S.F., Vorp D.A., Spievack A.R., Simmons-Byrd A., Hanke J., Freytes D.O., et al. Esophageal reconstruction with ECM and muscle tissue in a dog model. J Surg Res 128 1 (2005) 87-97
8. Yoo J.J., Meng J., Oberpenning F., and Atala A. Bladder augmentation using allogenic bladder submucosa seeded with cells. Urology 51 2 (1998) 221-225
9. Mills C.D., Kincaid K., Alt J.M., Heilman M.J., and Hill A.M. M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol 164 12 (2000) 6166-6173
10. Gordon S., and Taylor P.R. Monocyte and macrophage heterogeneity. Nat Rev Immunol 5 12 (2005) 953-964
11. Mantovani A., Sozzani S., Locati M., Allavena P., and Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23 11 (2002) 549-555
12. Mosser D.M. The many faces of macrophage activation. J Leukoc Biol 73 2 (2003) 209-212
13. Verreck F.A., de Boer T., Langenberg D.M., van der Zanden L., and Ottenhoff T.H. Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation. J Leukoc Biol 79 2 (2006) 285-293
14. Mantovani A., Sica A., Sozzani S., Allavena P., Vecchi A., and Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25 12 (2004) 677-686
15. Mantovani A., Sica A., and Locati M. Macrophage polarization comes of age. Immunity 23 4 (2005) 344-346
16. Porcheray F., Viaud S., Rimaniol A.C., Leone C., Samah B., Dereuddre-Bosquet N., et al. Macrophage activation switching: an asset for the resolution of inflammation. Clin Exp Immunol 142 3 (2005) 481-489
17. Stout R.D., Jiang C., Matta B., Tietzel I., Watkins S.K., and Suttles J. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol 175 1 (2005) 342-349
18. Stout R.D., and Suttles J. Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes. Immunol Rev 205 (2005) 60-71
19. Brown B., Lindberg K., Reing J., Stolz D.B., and Badylak S.F. The basement membrane component of biologic scaffolds derived from extracellular matrix. Tissue Eng 12 3 (2006) 519-526
20. Freytes D.O., Badylak S.F., Webster T.J., Geddes L.A., and Rundell A.E. Biaxial strength of multilaminated extracellular matrix scaffolds. Biomaterials 25 12 (2004) 2353-2361
21. Badylak S., Kokini K., Tullius B., Simmons-Byrd A., and Morff R. Morphologic study of small intestinal submucosa as a body wall repair device. J Surg Res 103 2 (2002) 190-202
22. Valentin J.E., Badylak J.S., McCabe G.P., and Badylak S.F. Extracellular matrix bioscaffolds for orthopaedic applications. A comparative histologic study. J Bone Joint Surg Am 88 12 (2006) 2673-2686
23. Schmittgen T.D., and Livak K.J. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3 6 (2008) 1101-1108
24. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25 4 (2001) 402-408
25. Gilbert T.W., Sellaro T.L., and Badylak S.F. Decellularization of tissues and organs. Biomaterials 27 19 (2006) 3675-3683
26. Allman A.J., McPherson T.B., Badylak S.F., Merrill L.C., Kallakury B., Sheehan C., et al. Xenogeneic extracellular matrix grafts elicit a TH2-restricted immune response. Transplantation 71 11 (2001) 1631-1640
27. van der Rest M., and Garrone R. Collagen family of proteins. FASEB J 5 13 (1991) 2814-2823
28. Gilbert T.W., Freund J.M., and Badylak S.F. Quantification of DNA in biologic scaffold materials. Tissue Eng 13 6 (2007) 1313-1323
29. McPherson T.B., Liang H., Record R.D., and Badylak S.F. Galalpha(1,3)Gal epitope in porcine small intestinal submucosa. Tissue Eng 6 3 (2000) 233-239
30. Galili U. The alpha-gal epitope (Gal alpha 1-3Gal beta 1-4GlcNAc-R) in xenotransplantation. Biochimie 83 7 (2001) 557-563
31. Parker W., Stitzenberg K.B., Yu P.B., Pratt V.S., Nakamura Y.C., Farel L.S., et al. Biophysical characteristics of anti-Gal(alpha)1-3Gal IgM binding to cell surfaces: implications for xenotransplantation. Transplantation 71 3 (2001) 440-446
32. Gilbert T.W., Stewart-Akers A.M., and Badylak S.F. A quantitative method for evaluating the degradation of biologic scaffold materials. Biomaterials 28 2 (2007) 147-150
33. Xu H., Wan H., Sandor M., Qi S., Ervin F., Harper J.R., et al. Host response to human acellular dermal matrix transplantation in a primate model of abdominal wall repair. Tissue Eng Part A 14 12 (2008) 2009-2201
34. Badylak S.F., Valentin J.E., Ravindra A.K., McCabe G.P., and Stewart-Akers A.M. Macrophage phenotype as a determinant of biologic scaffold remodeling. Tissue Eng Part A 14 11 (2008) 1835-1842
35. Martinez F.O., Gordon S., Locati M., and Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol 177 10 (2006) 7303-7311
36. Moestrup S.K., and Møller H.J. CD163: a regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response. Ann Med 36 5 (2004) 347-354