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Volumn 405, Issue 15, 2013, Pages 5105-5117

Hippocampal metabolomics using ultrahigh-resolution mass spectrometry reveals neuroinflammation from Alzheimer's disease in CRND8 mice

Author keywords

Alzheimer's disease; Arachidonic acid metabolism; FTMS; Hippocampus; Metabolomics

Indexed keywords

ALZHEIMER'S DISEASE; ARACHIDONIC ACIDS; FTMS; HIPPOCAMPUS; METABOLOMICS;

EID: 84878289356     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-6825-1     Document Type: Article
Times cited : (41)

References (38)
  • 1
    • 41149162296 scopus 로고    scopus 로고
    • Metabolomics: A global biochemical approach to drug response and disease
    • 10.1146/annurev.pharmtox.48.113006.094715 1:CAS:528:DC%2BD1cXisFymsrk%3D
    • Kaddurah-Daouk R, Kristal BS, Weinshilboum RM (2008) Metabolomics: a global biochemical approach to drug response and disease. Annu Rev Pharmacol Toxicol 48:653-683
    • (2008) Annu Rev Pharmacol Toxicol , vol.48 , pp. 653-683
    • Kaddurah-Daouk, R.1    Kristal, B.S.2    Weinshilboum, R.M.3
  • 2
    • 33845314350 scopus 로고    scopus 로고
    • Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors
    • 10.1158/0008-5472.CAN-06-0755 1:CAS:528:DC%2BD2sXivVyqsLc%3D
    • Denkert C, Budczies J, Kind T, Weichert W, Tablack P, Sehouli J, Niesporek S, Konsgen D, Dietel M, Fiehn O (2006) Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors. Cancer Res 66(22):10795-10804
    • (2006) Cancer Res , vol.66 , Issue.22 , pp. 10795-10804
    • Denkert, C.1    Budczies, J.2    Kind, T.3    Weichert, W.4    Tablack, P.5    Sehouli, J.6    Niesporek, S.7    Konsgen, D.8    Dietel, M.9    Fiehn, O.10
  • 3
    • 34347229424 scopus 로고    scopus 로고
    • Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method
    • 10.1021/ac062446p 1:CAS:528:DC%2BD2sXlsVSgurw%3D
    • Southam AD, Payne TG, Cooper HJ, Arvanitis TN, Viant MR (2007) Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method. Anal Chem 79(12):4595-4602
    • (2007) Anal Chem , vol.79 , Issue.12 , pp. 4595-4602
    • Southam, A.D.1    Payne, T.G.2    Cooper, H.J.3    Arvanitis, T.N.4    Viant, M.R.5
  • 4
    • 0036404889 scopus 로고    scopus 로고
    • Nontargeted metabolome analysis by use of fourier transform ion cyclotron mass spectrometry
    • 10.1089/15362310260256882 1:CAS:528:DC%2BD38Xnsl2ktLY%3D
    • Aharoni A, Ric de Vos CH, Verhoeven HA, Maliepaard CA, Kruppa G, Bino R, Goodenowe DB (2002) Nontargeted metabolome analysis by use of fourier transform ion cyclotron mass spectrometry. OMICS 6(3):217-234
    • (2002) OMICS , vol.6 , Issue.3 , pp. 217-234
    • Aharoni, A.1    Ric De Vos, C.H.2    Verhoeven, H.A.3    Maliepaard, C.A.4    Kruppa, G.5    Bino, R.6    Goodenowe, D.B.7
  • 5
    • 77950627695 scopus 로고    scopus 로고
    • Application of Fourier-transform ion cyclotron resonance mass spectrometry to metabolic profiling and metabolite identification
    • 10.1016/j.copbio.2010.01.012 1:CAS:528:DC%2BC3cXjslSjtb8%3D
    • Ohta D, Kanaya S, Suzuki H (2010) Application of Fourier-transform ion cyclotron resonance mass spectrometry to metabolic profiling and metabolite identification. Curr Opin Biotechnol 21(1):35-44
    • (2010) Curr Opin Biotechnol , vol.21 , Issue.1 , pp. 35-44
    • Ohta, D.1    Kanaya, S.2    Suzuki, H.3
  • 11
    • 0028866435 scopus 로고
    • The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway
    • 10.1038/nm1295-1291 1:CAS:528:DyaK2MXpslGhtbk%3D
    • Haass C, Lemere CA, Capell A, Citron M, Seubert P, Schenk D, Lannfelt L, Selkoe DJ (1995) The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway. Nat Med 1:1291-1296
    • (1995) Nat Med , vol.1 , pp. 1291-1296
    • Haass, C.1    Lemere, C.A.2    Capell, A.3    Citron, M.4    Seubert, P.5    Schenk, D.6    Lannfelt, L.7    Selkoe, D.J.8
  • 12
    • 72649085823 scopus 로고    scopus 로고
    • Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease
    • 10.1016/j.brainres.2009.11.040 1:CAS:528:DC%2BC3cXot1ar
    • Rustay NR, Cronin EA, Curzon P, Markosyan S, Bitner RS, Ellis TA, Waring JF, Decker MW, Rueter LE, Browman KE (2010) Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease. Brain Res 1311:136-147
    • (2010) Brain Res , vol.1311 , pp. 136-147
    • Rustay, N.R.1    Cronin, E.A.2    Curzon, P.3    Markosyan, S.4    Bitner, R.S.5    Ellis, T.A.6    Waring, J.F.7    Decker, M.W.8    Rueter, L.E.9    Browman, K.E.10
  • 13
    • 80052656815 scopus 로고    scopus 로고
    • The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing
    • 10.1111/j.1471-4159.2011.07412.x 1:CAS:528:DC%2BC3MXhtlyiurvL
    • Rabe S, Reichwald J, Ammaturo D, de Strooper B, Saftig P, Neumann U, Staufenbiel M (2011) The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing. J Neurochem 119(1):231-239
    • (2011) J Neurochem , vol.119 , Issue.1 , pp. 231-239
    • Rabe, S.1    Reichwald, J.2    Ammaturo, D.3    De Strooper, B.4    Saftig, P.5    Neumann, U.6    Staufenbiel, M.7
  • 14
    • 79954518834 scopus 로고    scopus 로고
    • Beyond glucose: Metabolic shifts in responses to the effects of the oral glucose tolerance test and the high-fructose diet in rats
    • 10.1039/c0mb00246a 1:CAS:528:DC%2BC3MXksFSis78%3D
    • Lin S, Yang Z, Liu H, Tang L, Cai Z (2011) Beyond glucose: metabolic shifts in responses to the effects of the oral glucose tolerance test and the high-fructose diet in rats. Mol Biosyst 7(5):1537-1548
    • (2011) Mol Biosyst , vol.7 , Issue.5 , pp. 1537-1548
    • Lin, S.1    Yang, Z.2    Liu, H.3    Tang, L.4    Cai, Z.5
  • 15
    • 79959998724 scopus 로고    scopus 로고
    • Hippocampal metabolomics reveals 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity associated with ageing in Sprague-Dawley rats
    • 10.1016/j.talanta.2011.05.007 1:CAS:528:DC%2BC3MXosFSktL4%3D
    • Lin S, Yang Z, Zhang X, Bian Z, Cai Z (2011) Hippocampal metabolomics reveals 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity associated with ageing in Sprague-Dawley rats. Talanta 85(2):1007-1012
    • (2011) Talanta , vol.85 , Issue.2 , pp. 1007-1012
    • Lin, S.1    Yang, Z.2    Zhang, X.3    Bian, Z.4    Cai, Z.5
  • 16
    • 84859863503 scopus 로고    scopus 로고
    • Dynamic eicosanoid responses upon different inhibitor and combination treatments on the arachidonic acid metabolic network
    • 10.1039/c2mb05503a 1:CAS:528:DC%2BC38XltFKntLc%3D
    • He C, Wu Y, Lai Y, Cai Z, Liu Y, Lai L (2012) Dynamic eicosanoid responses upon different inhibitor and combination treatments on the arachidonic acid metabolic network. Mol Biosyst 8(5):1585-1594
    • (2012) Mol Biosyst , vol.8 , Issue.5 , pp. 1585-1594
    • He, C.1    Wu, Y.2    Lai, Y.3    Cai, Z.4    Liu, Y.5    Lai, L.6
  • 18
    • 48449106046 scopus 로고    scopus 로고
    • MassTRIX: Mass translator into pathways
    • 10.1093/nar/gkn194 1:CAS:528:DC%2BD1cXptlKksbY%3D
    • Suhre K, Schmitt-Kopplin P (2008) MassTRIX: mass translator into pathways. Nucleic Acids Res 36(Web Server issue):W481-W484
    • (2008) Nucleic Acids Res , vol.36
    • Suhre, K.1    Schmitt-Kopplin, P.2
  • 19
    • 33847753038 scopus 로고    scopus 로고
    • Accurate cancer classification using expressions of very few genes
    • 10.1109/TCBB.2007.1006
    • Wang L, Chu F, Xie W (2007) Accurate cancer classification using expressions of very few genes. IEEE/ACM Trans Comput Biol Bioinform 4(1):40-53
    • (2007) IEEE/ACM Trans Comput Biol Bioinform , vol.4 , Issue.1 , pp. 40-53
    • Wang, L.1    Chu, F.2    Xie, W.3
  • 21
    • 79956129310 scopus 로고    scopus 로고
    • Characterization of isotopic abundance measurements in high resolution FT-ICR and Orbitrap mass spectra for improved confidence of metabolite identification
    • 10.1021/ac2001803 1:CAS:528:DC%2BC3MXkvVCmurs%3D
    • Weber RJ, Southam AD, Sommer U, Viant MR (2011) Characterization of isotopic abundance measurements in high resolution FT-ICR and Orbitrap mass spectra for improved confidence of metabolite identification. Anal Chem 83(10):3737-3743
    • (2011) Anal Chem , vol.83 , Issue.10 , pp. 3737-3743
    • Weber, R.J.1    Southam, A.D.2    Sommer, U.3    Viant, M.R.4
  • 22
    • 79957934380 scopus 로고    scopus 로고
    • Study of double bond equivalents and the numbers of carbon and oxygen atom distribution of dissolved organic matter with negative-mode FT-ICR MS
    • 10.1021/ac200464q 1:CAS:528:DC%2BC3MXlsFyrtLg%3D
    • Bae E, Yeo IJ, Jeong B, Shin Y, Shin KH, Kim S (2011) Study of double bond equivalents and the numbers of carbon and oxygen atom distribution of dissolved organic matter with negative-mode FT-ICR MS. Anal Chem 83(11):4193-4199
    • (2011) Anal Chem , vol.83 , Issue.11 , pp. 4193-4199
    • Bae, E.1    Yeo, I.J.2    Jeong, B.3    Shin, Y.4    Shin, K.H.5    Kim, S.6
  • 23
    • 84859403310 scopus 로고    scopus 로고
    • Compositional space boundaries for organic compounds
    • 10.1021/ac300244f 1:CAS:528:DC%2BC38XjtVCqsr0%3D
    • Lobodin VV, Marshall AG, Hsu CS (2012) Compositional space boundaries for organic compounds. Anal Chem 84(7):3410-3416
    • (2012) Anal Chem , vol.84 , Issue.7 , pp. 3410-3416
    • Lobodin, V.V.1    Marshall, A.G.2    Hsu, C.S.3
  • 24
    • 0029657725 scopus 로고    scopus 로고
    • Cytosolic phospholipase A(2) (cPLA(2)) immunoreactivity is elevated in Alzheimer's disease brain
    • 10.1006/nbdi.1996.0005 1:CAS:528:DyaK28Xis1Kqt7c%3D
    • Stephenson DT, Lemere CA, Selkoe DJ, Clemens JA (1996) Cytosolic phospholipase A(2) (cPLA(2)) immunoreactivity is elevated in Alzheimer's disease brain. Neurobiol Dis 3(1):51-63
    • (1996) Neurobiol Dis , vol.3 , Issue.1 , pp. 51-63
    • Stephenson, D.T.1    Lemere, C.A.2    Selkoe, D.J.3    Clemens, J.A.4
  • 25
    • 0031449545 scopus 로고    scopus 로고
    • Serum amyloid A (SAA) protein enhances formation of cyclooxygenase metabolites of activated human monocytes
    • 10.1016/S0014-5793(97)01459-2 1:CAS:528:DyaK2sXnvFGksLg%3D
    • Malle E, Bollmann A, Steinmetz A, Gemsa D, Leis HJ, Sattler W (1997) Serum amyloid A (SAA) protein enhances formation of cyclooxygenase metabolites of activated human monocytes. FEBS Lett 419(2-3):215-219
    • (1997) FEBS Lett , vol.419 , Issue.2-3 , pp. 215-219
    • Malle, E.1    Bollmann, A.2    Steinmetz, A.3    Gemsa, D.4    Leis, H.J.5    Sattler, W.6
  • 26
    • 69349095118 scopus 로고    scopus 로고
    • Alterations in excitotoxicity and prostaglandin metabolism in a transgenic mouse model of Alzheimer's disease
    • 10.1016/j.neuint.2009.06.010 1:CAS:528:DC%2BD1MXhtV2qsr7M
    • Schulte EC, Slawik H, Schule R, Gunther T, Hull M (2009) Alterations in excitotoxicity and prostaglandin metabolism in a transgenic mouse model of Alzheimer's disease. Neurochem Int 55(7):689-696
    • (2009) Neurochem Int , vol.55 , Issue.7 , pp. 689-696
    • Schulte, E.C.1    Slawik, H.2    Schule, R.3    Gunther, T.4    Hull, M.5
  • 27
    • 77953279191 scopus 로고    scopus 로고
    • Phospholipase A2 and arachidonic acid in Alzheimer's disease
    • 10.1016/j.bbalip.2010.05.013 1:CAS:528:DC%2BC3cXntlagsr0%3D
    • Sanchez-Mejia RO, Mucke L (2010) Phospholipase A2 and arachidonic acid in Alzheimer's disease. Biochim Biophys Acta 1801(8):784-790
    • (2010) Biochim Biophys Acta , vol.1801 , Issue.8 , pp. 784-790
    • Sanchez-Mejia, R.O.1    Mucke, L.2
  • 28
    • 84856950778 scopus 로고    scopus 로고
    • Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: Structural insight
    • 10.1016/j.neurobiolaging.2011.07.014 e21-31
    • Amtul Z, Uhrig M, Wang L, Rozmahel RF, Beyreuther K (2012) Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight. Neurobiol Aging 33(4):831, e21-31
    • (2012) Neurobiol Aging , vol.33 , Issue.4 , pp. 831
    • Amtul, Z.1    Uhrig, M.2    Wang, L.3    Rozmahel, R.F.4    Beyreuther, K.5
  • 29
    • 0032767601 scopus 로고    scopus 로고
    • Screening for fatty acid beta oxidation disorders. Acylglycine analysis by electron impact ionization gas chromatography-mass spectrometry
    • 10.1016/S0378-4347(99)00208-X 1:CAS:528:DyaK1MXlt1Sjurw%3D
    • Kimura M, Yamaguchi S (1999) Screening for fatty acid beta oxidation disorders. Acylglycine analysis by electron impact ionization gas chromatography-mass spectrometry. J Chromatogr B: Biomed Sci Appl 731(1):105-110
    • (1999) J Chromatogr B: Biomed Sci Appl , vol.731 , Issue.1 , pp. 105-110
    • Kimura, M.1    Yamaguchi, S.2
  • 31
    • 33644748224 scopus 로고    scopus 로고
    • Reliability of different blood indices to explore the oxidative stress in response to maximal cycling and static exercises
    • 10.1111/j.1475-097X.2006.00658.x 1:CAS:528:DC%2BD28XktFWjurk%3D
    • Steinberg JG, Delliaux S, Jammes Y (2006) Reliability of different blood indices to explore the oxidative stress in response to maximal cycling and static exercises. Clin Physiol Funct Imag 26(2):106-112
    • (2006) Clin Physiol Funct Imag , vol.26 , Issue.2 , pp. 106-112
    • Steinberg, J.G.1    Delliaux, S.2    Jammes, Y.3
  • 33
    • 3042567711 scopus 로고    scopus 로고
    • Inflammation occurs early during the Abeta deposition process in TgCRND8 mice
    • 10.1016/j.neurobiolaging.2003.08.008 1:CAS:528:DC%2BD2cXltVGjurc%3D
    • Dudal S, Krzywkowski P, Paquette J, Morissette C, Lacombe D, Tremblay P, Gervais F (2004) Inflammation occurs early during the Abeta deposition process in TgCRND8 mice. Neurobiol Aging 25(7):861-871
    • (2004) Neurobiol Aging , vol.25 , Issue.7 , pp. 861-871
    • Dudal, S.1    Krzywkowski, P.2    Paquette, J.3    Morissette, C.4    Lacombe, D.5    Tremblay, P.6    Gervais, F.7
  • 34
    • 73949145739 scopus 로고    scopus 로고
    • Amyloid deposition and inflammation in APPswe/PS1dE9 mouse model of Alzheimer's disease
    • 10.2174/156720509790147070 1:CAS:528:DC%2BD1MXhsFCitrjM
    • Ruan L, Kang Z, Pei G, Le Y (2009) Amyloid deposition and inflammation in APPswe/PS1dE9 mouse model of Alzheimer's disease. Curr Alzheimer Res 6(6):531-540
    • (2009) Curr Alzheimer Res , vol.6 , Issue.6 , pp. 531-540
    • Ruan, L.1    Kang, Z.2    Pei, G.3    Le, Y.4
  • 35
    • 84861183285 scopus 로고    scopus 로고
    • Intracellular Abeta-oligomers and early inflammation in a model of Alzheimer's disease
    • 10.1016/j.neurobiolaging.2011.01.007 1:CAS:528:DC%2BC38Xnt1KqsLg%3D
    • Ferretti MT, Bruno MA, Ducatenzeiler A, Klein WL, Cuello AC (2012) Intracellular Abeta-oligomers and early inflammation in a model of Alzheimer's disease. Neurobiol Aging 33(7):1329-1342
    • (2012) Neurobiol Aging , vol.33 , Issue.7 , pp. 1329-1342
    • Ferretti, M.T.1    Bruno, M.A.2    Ducatenzeiler, A.3    Klein, W.L.4    Cuello, A.C.5
  • 36
    • 36549083642 scopus 로고    scopus 로고
    • Neuroinflammation: Implications for the pathogenesis and molecular diagnosis of Alzheimer's disease
    • 10.1016/j.arcmed.2007.10.001 1:CAS:528:DC%2BD2sXhsVSmtbvM
    • Rojo LE, Fernandez JA, Maccioni AA, Jimenez JM, Maccioni RB (2008) Neuroinflammation: implications for the pathogenesis and molecular diagnosis of Alzheimer's disease. Arch Med Res 39(1):1-16
    • (2008) Arch Med Res , vol.39 , Issue.1 , pp. 1-16
    • Rojo, L.E.1    Fernandez, J.A.2    Maccioni, A.A.3    Jimenez, J.M.4    Maccioni, R.B.5
  • 37
    • 30644479192 scopus 로고    scopus 로고
    • Clinical aspects of inflammation in Alzheimer's disease
    • 10.1080/02646830500382037
    • Rosenberg PB (2005) Clinical aspects of inflammation in Alzheimer's disease. Int Rev Psychiatry 17(6):503-514
    • (2005) Int Rev Psychiatry , vol.17 , Issue.6 , pp. 503-514
    • Rosenberg, P.B.1
  • 38
    • 78650452885 scopus 로고    scopus 로고
    • Neuroinflammation in Alzheimer's disease: Are NSAIDs and selective COX-2 inhibitors the next line of therapy?
    • 1:CAS:528:DC%2BC3cXhtlOhtrzI
    • Trepanier CH, Milgram NW (2010) Neuroinflammation in Alzheimer's disease: are NSAIDs and selective COX-2 inhibitors the next line of therapy? J Alzheimers Dis 21(4):1089-1099
    • (2010) J Alzheimers Dis , vol.21 , Issue.4 , pp. 1089-1099
    • Trepanier, C.H.1    Milgram, N.W.2


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