Central TNF inhibition results in attenuated neurohumoral excitation in heart failure: A role for superoxide and nitric oxide

Basic Research in Cardiology

Volumn 106, Issue 2, 2011, Pages 273-286

  Guggilam, Anuradha ^a   Cardinale, Jeffrey P ^a   Mariappan, Nithya ^a   Sriramula, Srinivas ^a   Haque, Masudul ^a   Francis, Joseph ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Congestive heart failure; Oxidant stress; Paraventricular nucleus; Rostral ventrolateral medullary nucleus; Sympathoexcitation; Tumor necrosis factor

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ETANERCEPT; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NORADRENALIN; PEROXYNITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; IMMUNOGLOBULIN G; SODIUM; TNFR FC FUSION PROTEIN; TNFR-FC FUSION PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CELL COUNT; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DISEASE COURSE; ELECTROLYTE DISTURBANCE; FLUID RETENTION; GENE EXPRESSION; HEART FUNCTION; HEART INFARCTION; HOMEOSTASIS; HYPOTHALAMUS; MALE; MOUSE; NERVE CELL; NERVE STIMULATION; NONHUMAN; NORADRENALIN BLOOD LEVEL; OXIDATIVE STRESS; PATHOPHYSIOLOGY; SODIUM RETENTION; SYMPATHETIC NERVE; ADRENERGIC SYSTEM; ANIMAL; DRUG ANTAGONISM; HEART FAILURE; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; METABOLISM; MOUSE MUTANT;

ANIMALS; BRAIN STEM; CYTOKINES; DISEASE PROGRESSION; HEART FAILURE; HOMEOSTASIS; IMMUNOGLOBULIN G; MALE; MICE; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; NITRIC OXIDE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, TUMOR NECROSIS FACTOR; SODIUM; SUPEROXIDES; SYMPATHETIC NERVOUS SYSTEM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79957807435     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-010-0146-8     Document Type: Article

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