-
1
-
-
85006768050
-
The metabolism of tumors in the body
-
10.1085/jgp.8.6.519 1:CAS:528:DyaB2sXitlyhuw%3D%3D
-
Warburg O, Wind F, Negelein E (1927) The metabolism of tumors in the body. J Gen Physiol 8:519
-
(1927)
J Gen Physiol
, vol.8
, pp. 519
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
2
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
10.1126/science.1160809
-
Vander Heiden MG, Cantley LC, Thompson CB (2012) Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324:1029
-
(2012)
Science
, vol.324
, pp. 1029
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
3
-
-
44449147036
-
Tumor cell metabolism: Cancer's Achilles' heel
-
10.1016/j.ccr.2008.05.005 1:CAS:528:DC%2BD1cXns1yhtb0%3D
-
Kroemer G, Pouyssegur J (2008) Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 13:472
-
(2008)
Cancer Cell
, vol.13
, pp. 472
-
-
Kroemer, G.1
Pouyssegur, J.2
-
4
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
10.1016/j.cell.2011.02.013
-
Hanahan D, Weinberg RA (2012) Hallmarks of cancer: the next generation. Cell 144:646
-
(2012)
Cell
, vol.144
, pp. 646
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
77953388453
-
How close is the bench to the bedside? Metabolic profiling in cancer research
-
10.1186/gm5
-
Van QN, Veenstra TD (2009) How close is the bench to the bedside? Metabolic profiling in cancer research. Genome Med 1:5
-
(2009)
Genome Med
, vol.1
, pp. 5
-
-
Van, Q.N.1
Veenstra, T.D.2
-
6
-
-
84866488967
-
Metabolomics in cancer: A bench-to-bedside intersection
-
10.1016/j.critrevonc.2012.02.009
-
Claudino WM, Goncalves PH, di Leo A, Philip PA, Sarkar FH (2012) Metabolomics in cancer: a bench-to-bedside intersection. Crit Rev Oncol Hematol 84:1
-
(2012)
Crit Rev Oncol Hematol
, vol.84
, pp. 1
-
-
Claudino, W.M.1
Goncalves, P.H.2
Di Leo, A.3
Philip, P.A.4
Sarkar, F.H.5
-
7
-
-
2942709840
-
Metabolic profiles to define the genome: Can we hear the phenotypes?
-
10.1098/rstb.2003.1411 1:CAS:528:DC%2BD2cXmt1yms70%3D
-
Griffin JL (2004) Metabolic profiles to define the genome: can we hear the phenotypes? Philos Trans R Soc B Biol Sci 359:857
-
(2004)
Philos Trans R Soc B Biol Sci
, vol.359
, pp. 857
-
-
Griffin, J.L.1
-
8
-
-
0034959944
-
Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks
-
10.1002/cfg.82 1:CAS:528:DC%2BD3MXlsVCntbw%3D
-
Fiehn O (2001) Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks. Comp Funct Genom 2:155
-
(2001)
Comp Funct Genom
, vol.2
, pp. 155
-
-
Fiehn, O.1
-
9
-
-
78649711427
-
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes
-
10.1126/science.1193494 1:CAS:528:DC%2BC3cXhsVyrsbbL
-
Levine AJ, Puzio-Kuter AM (2010) The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes. Science 330:1340
-
(2010)
Science
, vol.330
, pp. 1340
-
-
Levine, A.J.1
Puzio-Kuter, A.M.2
-
10
-
-
79955398591
-
Otto Warburg's contributions to current concepts of cancer metabolism
-
10.1038/nrc3038 1:CAS:528:DC%2BC3MXks1ags70%3D
-
Koppenol WH, Bounds PL, Dang CV (2011) Otto Warburg's contributions to current concepts of cancer metabolism. Nat Rev Cancer 11:325
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 325
-
-
Koppenol, W.H.1
Bounds, P.L.2
Dang, C.V.3
-
11
-
-
85027954364
-
The Warburg effect in 2012
-
10.1097/CCO.0b013e32834deb9e 1:CAS:528:DC%2BC3MXhs1Shu7vM
-
Bayley J-P, Devilee P (2012) The Warburg effect in 2012. Curr Opin Oncol 24:62
-
(2012)
Curr Opin Oncol
, vol.24
, pp. 62
-
-
Bayley, J.-P.1
Devilee, P.2
-
12
-
-
79956123670
-
Metabolism and cancer: An up-to-date review of a mutual connection
-
Mentis A-FA, Kararizou E (2010) Metabolism and cancer: an up-to-date review of a mutual connection. Asian Pacific J Cancer Prev 11:1437
-
(2010)
Asian Pacific J Cancer Prev
, vol.11
, pp. 1437
-
-
Mentis, A.-F.1
Kararizou, E.2
-
13
-
-
33750619348
-
Glucose metabolism and cancer
-
10.1016/j.ceb.2006.10.005 1:CAS:528:DC%2BD28XhtF2qtbjI
-
Shaw RJ (2006) Glucose metabolism and cancer. Curr Opin Cell Biol 18:598
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 598
-
-
Shaw, R.J.1
-
14
-
-
79959997219
-
-
ACS American Cancer Society, Atlanta, Georgia
-
ACS (2011) Colorectal cancer facts & figures 2011-2013. American Cancer Society, Atlanta, Georgia. http://www.cancer.org/research/ cancerfactsfigures/colorectalcancerfactsfigures/colorectal-cancer-facts-figures- 2011-2013-page
-
(2011)
Colorectal Cancer Facts & Figures 2011-2013
-
-
-
15
-
-
0003397692
-
-
ACS American Cancer Society, Atlanta, Georgia
-
ACS (2012) Cancer facts & figures 2012. American Cancer Society, Atlanta, Georgia. http://www.cancer.org/acs/groups/content/ @epidemiologysurveilance/documents/document/acspc-031941.pdf
-
(2012)
Cancer Facts & Figures 2012
-
-
-
16
-
-
70350028279
-
Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS
-
10.1021/pr9004162 1:CAS:528:DC%2BD1MXhtV2murrM
-
Qiu Y, Cai G, Su M, Chen T, Zheng X, Xu Y, Ni Y, Zhao A, Xu LX, Cai S, Jia W (2009) Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS. J Proteome Res 8:4844
-
(2009)
J Proteome Res
, vol.8
, pp. 4844
-
-
Qiu, Y.1
Cai, G.2
Su, M.3
Chen, T.4
Zheng, X.5
Xu, Y.6
Ni, Y.7
Zhao, A.8
Xu, L.X.9
Cai, S.10
Jia, W.11
-
17
-
-
84863024905
-
Distinct urinary metabolic profile of human colorectal cancer
-
10.1021/pr201001a 1:CAS:528:DC%2BC3MXhsF2jsrzL
-
Cheng Y, Xie G, Chen T, Qiu Y, Zou X, Zheng M, Tan B, Feng B, Dong T, He P, Zhao L, Zhao A, Xu LX, Zhang Y, Jia W (2012) Distinct urinary metabolic profile of human colorectal cancer. J Proteome Res 11:1354
-
(2012)
J Proteome Res
, vol.11
, pp. 1354
-
-
Cheng, Y.1
Xie, G.2
Chen, T.3
Qiu, Y.4
Zou, X.5
Zheng, M.6
Tan, B.7
Feng, B.8
Dong, T.9
He, P.10
Zhao, L.11
Zhao, A.12
Xu, L.X.13
Zhang, Y.14
Jia, W.15
-
18
-
-
60849139445
-
Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS)
-
10.1021/pr8006232 1:CAS:528:DC%2BD1cXhsVOnsLnN
-
Chan EC, Koh PK, Mal M, Cheah PY, Eu KW, Backshall A, Cavill R, Nicholson JK, Keun HC (2009) Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS). J Proteome Res 8:352
-
(2009)
J Proteome Res
, vol.8
, pp. 352
-
-
Chan, E.C.1
Koh, P.K.2
Mal, M.3
Cheah, P.Y.4
Eu, K.W.5
Backshall, A.6
Cavill, R.7
Nicholson, J.K.8
Keun, H.C.9
-
19
-
-
33846000626
-
Mass spectrometry-based metabolomics
-
10.1002/mas.20108 1:CAS:528:DC%2BD2sXht1anur8%3D
-
Dettmer K, Aronov PA, Hammock BD (2007) Mass spectrometry-based metabolomics. Mass Spectrom Rev 26:51
-
(2007)
Mass Spectrom Rev
, vol.26
, pp. 51
-
-
Dettmer, K.1
Aronov, P.A.2
Hammock, B.D.3
-
20
-
-
16244402990
-
Metabolomics: Current analytical platforms and methodologies
-
10.1016/j.trac.2004.11.021 1:CAS:528:DC%2BD2MXivVKru74%3D
-
Dunn WB, Ellis DI (2005) Metabolomics: Current analytical platforms and methodologies. Trends Anal Chem 24:285
-
(2005)
Trends Anal Chem
, vol.24
, pp. 285
-
-
Dunn, W.B.1
Ellis, D.I.2
-
21
-
-
18844406001
-
Measuring the metabolome: Current analytical technologies
-
Dunn WB, Bailey NJC, Johnson HE (2005) Measuring the metabolome: current analytical technologies. Analyst 130
-
(2005)
Analyst
, pp. 130
-
-
Dunn, W.B.1
Bailey, N.J.C.2
Johnson, H.E.3
-
22
-
-
41049099137
-
Current and emerging mass-spectrometry technologies for metabolomics
-
10.1016/j.trac.2008.01.006 1:CAS:528:DC%2BD1cXjvF2jtLY%3D
-
Bedair M, Sumner LW (2008) Current and emerging mass-spectrometry technologies for metabolomics. Trends Anal Chem 27:238
-
(2008)
Trends Anal Chem
, vol.27
, pp. 238
-
-
Bedair, M.1
Sumner, L.W.2
-
23
-
-
41149178478
-
LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics
-
10.1016/j.trac.2008.01.008 1:CAS:528:DC%2BD1cXjvF2jtb4%3D
-
Theodoridis G, Gika HG, Wilson ID (2008) LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics. Trends Anal Chem 27:251
-
(2008)
Trends Anal Chem
, vol.27
, pp. 251
-
-
Theodoridis, G.1
Gika, H.G.2
Wilson, I.D.3
-
24
-
-
0027613513
-
Increased aspartate and glutamate levels in both gastric and colon cancer tissues
-
1:STN:280:DyaK2c%2FisVyksg%3D%3D
-
Okada A, Takehara H, Yoshida K, Nishi M, Miyake H, Kita Y, Komi N (1993) Increased aspartate and glutamate levels in both gastric and colon cancer tissues. Tokushima J Exp Med 40:19
-
(1993)
Tokushima J Exp Med
, vol.40
, pp. 19
-
-
Okada, A.1
Takehara, H.2
Yoshida, K.3
Nishi, M.4
Miyake, H.5
Kita, Y.6
Komi, N.7
-
25
-
-
0032951381
-
Increased choline kinase activity and elevated phosphocholine levels in human colon cancer
-
10.1111/j.1349-7006.1999.tb00764.x 1:CAS:528:DyaK1MXislGrtr0%3D
-
Nakagami K, Uchida T, Ohwada S, Koibuchi Y, Suda Y, Sekine T, Morishita Y (1999) Increased choline kinase activity and elevated phosphocholine levels in human colon cancer. Jpn J Cancer Res 90:419
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 419
-
-
Nakagami, K.1
Uchida, T.2
Ohwada, S.3
Koibuchi, Y.4
Suda, Y.5
Sekine, T.6
Morishita, Y.7
-
26
-
-
79952433343
-
Metabolic profiling in colorectal cancer reveals signature metabolic shifts during tumorigenesis
-
doi: 10.1074/mcp.M900551-MCP200
-
Ong ES, Zou L, Li S, Cheah PY, Eu KW, Ong CN (2010) Metabolic profiling in colorectal cancer reveals signature metabolic shifts during tumorigenesis. Mol Cell Proteomics. doi: 10.1074/mcp.M900551-MCP200
-
(2010)
Mol Cell Proteomics.
-
-
Ong, E.S.1
Zou, L.2
Li, S.3
Cheah, P.Y.4
Eu, K.W.5
-
27
-
-
54349088296
-
Metabolite profiling of human colon carcinoma - Deregulation of TCA cycle and amino acid turnover
-
Denkert C, Budczies J, Weichert W, Wohlgemuth G, Scholz M, Kind T, Niesporek S, Noske A, Buckendahl A, Dietel M, Fiehn O (2008) Metabolite profiling of human colon carcinoma - deregulation of TCA cycle and amino acid turnover. Mol Cancer 7
-
(2008)
Mol Cancer
, pp. 7
-
-
Denkert, C.1
Budczies, J.2
Weichert, W.3
Wohlgemuth, G.4
Scholz, M.5
Kind, T.6
Niesporek, S.7
Noske, A.8
Buckendahl, A.9
Dietel, M.10
Fiehn, O.11
-
28
-
-
60549109691
-
Development and validation of a gas chromatography/mass spectrometry method for the metabolic profiling of human colon tissue
-
10.1002/rcm.3898 1:CAS:528:DC%2BD1MXitVakt70%3D
-
Mal M, Koh PK, Cheah PY, Chan ECY (2009) Development and validation of a gas chromatography/mass spectrometry method for the metabolic profiling of human colon tissue. Rapid Commun Mass Spectrom 23:487
-
(2009)
Rapid Commun Mass Spectrom
, vol.23
, pp. 487
-
-
Mal, M.1
Koh, P.K.2
Cheah, P.Y.3
Chan, E.C.Y.4
-
29
-
-
66349095388
-
Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry
-
10.1158/0008-5472.CAN-08-4806 1:CAS:528:DC%2BD1MXmsFGks74%3D
-
Hirayama A, Kami K, Sugimoto M, Sugawara M, Toki N, Onozuka H, Kinoshita T, Saito N, Ochiai A, Tomita M, Esumi H, Soga T (2009) Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry. Cancer Res 69:4918
-
(2009)
Cancer Res
, vol.69
, pp. 4918
-
-
Hirayama, A.1
Kami, K.2
Sugimoto, M.3
Sugawara, M.4
Toki, N.5
Onozuka, H.6
Kinoshita, T.7
Saito, N.8
Ochiai, A.9
Tomita, M.10
Esumi, H.11
Soga, T.12
-
30
-
-
43749095186
-
Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy
-
Seierstad T, Røe K, Sitter B, Halgunset J, Flatmark K, Ree AH, Olsen D, Gribbestad IS, Bathen TF (2008) Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy. Mol Cancer 7
-
(2008)
Mol Cancer
, pp. 7
-
-
Seierstad T, R.1
-
31
-
-
70149102858
-
Metabolic characterization of primary human colorectal cancers using high resolution magic angle spinning 1H magnetic resonance spectroscopy
-
10.1007/s11306-008-0151-1
-
Piotto M, Moussallieh FM, Dillmann B, Imperiale A, Neuville A, Brigand C, Bellocq JP, Elbayed K, Namer IJ (2008) Metabolic characterization of primary human colorectal cancers using high resolution magic angle spinning 1H magnetic resonance spectroscopy. Metabolomics 5:292
-
(2008)
Metabolomics
, vol.5
, pp. 292
-
-
Piotto, M.1
Moussallieh, F.M.2
Dillmann, B.3
Imperiale, A.4
Neuville, A.5
Brigand, C.6
Bellocq, J.P.7
Elbayed, K.8
Namer, I.J.9
-
32
-
-
77954366517
-
Discrimination of patients with microsatellite instability colon cancer using 1H HR MAS MR spectroscopy and chemometric analysis
-
10.1021/pr100176g 1:CAS:528:DC%2BC3cXnsVagu7c%3D
-
Tessem M-B, Selnæs KM, Sjursen W, Tranø G, Giskeødegård GF, Bathen TF, Gribbestad IS, Hofsli E (2010) Discrimination of patients with microsatellite instability colon cancer using 1H HR MAS MR spectroscopy and chemometric analysis. J Proteome Res 9:3664
-
(2010)
J Proteome Res
, vol.9
, pp. 3664
-
-
Tessem, M.-B.1
Selnæs, K.M.2
Sjursen, W.3
Tranø, G.4
Giskeødegård, G.F.5
Bathen, T.F.6
Gribbestad, I.S.7
Hofsli, E.8
-
33
-
-
77951799535
-
Combining information of common metabolites reveals global differences between colorectal cancerous and normal tissues
-
10.5012/bkcs.2010.31.02.379 1:CAS:528:DC%2BC3cXktFKls7k%3D
-
Chae Y-K, Kang W-Y, Kim S-H, Joo J-E, Han J-K, Hong B-W (2010) Combining information of common metabolites reveals global differences between colorectal cancerous and normal tissues. Bull Korean Chem Soc 31:379
-
(2010)
Bull Korean Chem Soc
, vol.31
, pp. 379
-
-
Chae, Y.-K.1
Kang, W.-Y.2
Kim, S.-H.3
Joo, J.-E.4
Han, J.-K.5
Hong, B.-W.6
-
34
-
-
72249107538
-
Fast targeted multidimensional NMR metabolomics of colorectal cancer
-
10.1002/mrc.2519 1:CAS:528:DC%2BD1MXhsFeku7nM
-
Ludwig C, Ward DG, Martin A, Viant MR, Ismail T, Johnson PJ, Wakelam MJO, Günther UL (2009) Fast targeted multidimensional NMR metabolomics of colorectal cancer. Magn Reson Chem 47:S68
-
(2009)
Magn Reson Chem
, vol.47
, pp. 68
-
-
Ludwig, C.1
Ward, D.G.2
Martin, A.3
Viant, M.R.4
Ismail, T.5
Johnson, P.J.6
Wakelam, M.J.O.7
Günther, U.L.8
-
35
-
-
84855390232
-
Metabolomic NMR fingerprinting to identify and predict survival of patients with metastatic colorectal cancer
-
10.1158/0008-5472.CAN-11-1543 1:CAS:528:DC%2BC38XhvVCrsQ%3D%3D
-
Bertini I, Cacciatore S, Jensen BV, Schou JV, Johansen JS, Kruhoffer M, Luchinat C, Nielsen DL, Turano P (2012) Metabolomic NMR fingerprinting to identify and predict survival of patients with metastatic colorectal cancer. Cancer Res 72:356
-
(2012)
Cancer Res
, vol.72
, pp. 356
-
-
Bertini, I.1
Cacciatore, S.2
Jensen, B.V.3
Schou, J.V.4
Johansen, J.S.5
Kruhoffer, M.6
Luchinat, C.7
Nielsen, D.L.8
Turano, P.9
-
36
-
-
77949479965
-
Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: Implications for early screening and detection
-
Ritchie SA, Ahiahonu PWK, Jayasinghe D, Heath D, Liu J, Lu Y, Jin W, Kavianpour A, Yamazaki Y, Khan AM, Hossain M, Su-Myat KK, Wood PL, Krenitsky K, Takemasa I, Miyake M, Sekimoto M, Monden M, Matsubara H, Nomura F, Goodenowe DB (2010) Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection. BMC Med 8
-
(2010)
BMC Med
, pp. 8
-
-
Ritchie, S.A.1
Pwk, A.2
Jayasinghe, D.3
Heath, D.4
Liu, J.5
Lu, Y.6
Jin, W.7
Kavianpour, A.8
Yamazaki, Y.9
Khan, A.M.10
Hossain, M.11
Su-Myat, K.K.12
Wood, P.L.13
Krenitsky, K.14
Takemasa, I.15
Miyake, M.16
Sekimoto, M.17
Monden, M.18
Matsubara, H.19
Nomura, F.20
Goodenowe, D.B.21
more..
-
37
-
-
33947427846
-
Evaluation of metabolite extraction strategies from tissue samples using NMR metabolomics
-
10.1007/s11306-006-0043-1 1:CAS:528:DC%2BD2sXktVOhu70%3D
-
Lin CY, Wu H, Tjeerdema RS, Viant MR (2007) Evaluation of metabolite extraction strategies from tissue samples using NMR metabolomics. Metabolomics 3:55
-
(2007)
Metabolomics
, vol.3
, pp. 55
-
-
Lin, C.Y.1
Wu, H.2
Tjeerdema, R.S.3
Viant, M.R.4
-
38
-
-
36148989929
-
High-throughput tissue extraction protocol for NMR- and MS-based metabolomics
-
10.1016/j.ab.2007.10.002 1:CAS:528:DC%2BD2sXhtlGjtb%2FL
-
Wu H, Southam AD, Hines A, Viant MR (2008) High-throughput tissue extraction protocol for NMR- and MS-based metabolomics. Anal Biochem 372:204
-
(2008)
Anal Biochem
, vol.372
, pp. 204
-
-
Wu, H.1
Southam, A.D.2
Hines, A.3
Viant, M.R.4
-
39
-
-
33745700684
-
Impact of analytical bias in metabonomic studies of human blood serum and plasma
-
10.1021/ac051972y 1:CAS:528:DC%2BD28XksFKktLk%3D
-
Teahan O, Gamble S, Holmes E, Waxman J, Nicholson JK, Bevan C, Keun HC (2006) Impact of analytical bias in metabonomic studies of human blood serum and plasma. Anal Chem 78:4307
-
(2006)
Anal Chem
, vol.78
, pp. 4307
-
-
Teahan, O.1
Gamble, S.2
Holmes, E.3
Waxman, J.4
Nicholson, J.K.5
Bevan, C.6
Keun, H.C.7
-
40
-
-
32444451016
-
Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry
-
10.1021/ac051312t 1:CAS:528:DC%2BD28XhtFehurs%3D
-
Want EJ, O'Maille G, Smith CA, Brandon TR, Uritboonthai W, Qin C, Trauger SA, Siuzdak G (2006) Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry. Anal Chem 78:743
-
(2006)
Anal Chem
, vol.78
, pp. 743
-
-
Want, E.J.1
O'Maille, G.2
Smith, C.A.3
Brandon, T.R.4
Uritboonthai, W.5
Qin, C.6
Trauger, S.A.7
Siuzdak, G.8
-
41
-
-
66149126908
-
Investigation of human blood plasma sample preparation for performing metabolomics using ultrahigh performance liquid chromatography/mass spectrometry
-
10.1021/ac8024569 1:CAS:528:DC%2BD1MXjslyqsLY%3D
-
Bruce SJ, Tavazzi I, Parisod V, Rezzi S, Kochhar S, Guy PA (2009) Investigation of human blood plasma sample preparation for performing metabolomics using ultrahigh performance liquid chromatography/mass spectrometry. Anal Chem 81:3285
-
(2009)
Anal Chem
, vol.81
, pp. 3285
-
-
Bruce, S.J.1
Tavazzi, I.2
Parisod, V.3
Rezzi, S.4
Kochhar, S.5
Guy, P.A.6
-
42
-
-
27944492417
-
Controlled protein precipitation in combination with chip-based nanospray infusion mass spectrometry. An approach for metabolomics profiling of plasma
-
10.1021/ac0508604 1:CAS:528:DC%2BD2MXhtFSjtrnO
-
Boernsen KO, Gatzek S, Imbert G (2005) Controlled protein precipitation in combination with chip-based nanospray infusion mass spectrometry. An approach for metabolomics profiling of plasma. Anal Chem 77:7255
-
(2005)
Anal Chem
, vol.77
, pp. 7255
-
-
Boernsen, K.O.1
Gatzek, S.2
Imbert, G.3
-
43
-
-
67249106875
-
Large-scale human metabolic phenotyping and molecular epidemiological studies via 1H NMR spectroscopy of urine: Investigation of borate preservation
-
10.1021/ac9004875 1:CAS:528:DC%2BD1MXmtVGrs7k%3D
-
Smith LM, Maher AD, Want EJ, Elliott P, Stamler J, Hawkes GE, Holmes E, Lindon JC, Nicholson JK (2009) Large-scale human metabolic phenotyping and molecular epidemiological studies via 1H NMR spectroscopy of urine: investigation of borate preservation. Anal Chem 81:4847
-
(2009)
Anal Chem
, vol.81
, pp. 4847
-
-
Smith, L.M.1
Maher, A.D.2
Want, E.J.3
Elliott, P.4
Stamler, J.5
Hawkes, G.E.6
Holmes, E.7
Lindon, J.C.8
Nicholson, J.K.9
-
44
-
-
0345490738
-
A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects
-
10.1016/S0731-7085(03)00410-2 1:CAS:528:DC%2BD3sXptlymtb0%3D
-
Lenz EM, Bright J, Wilson ID, Morgan SR, Nash AFP (2003) A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects. J Pharm Biomed Anal 33:1103
-
(2003)
J Pharm Biomed Anal
, vol.33
, pp. 1103
-
-
Lenz, E.M.1
Bright, J.2
Wilson, I.D.3
Morgan, S.R.4
Nash, A.F.P.5
-
45
-
-
0035811974
-
Diagnosis of inborn errors of metabolism using filter paper urine, urease treatment, isotope dilution and gas chromatography-mass spectrometry
-
10.1016/S0378-4347(01)00138-4 1:CAS:528:DC%2BD3MXjvV2msLo%3D
-
Kuhara T (2001) Diagnosis of inborn errors of metabolism using filter paper urine, urease treatment, isotope dilution and gas chromatography-mass spectrometry. J Chromatogr B: Biomed Sci Appl 758:3
-
(2001)
J Chromatogr B: Biomed Sci Appl
, vol.758
, pp. 3
-
-
Kuhara, T.1
-
46
-
-
64649089947
-
Cross-platform comparison of methods for quantitative metabolomics of primary metabolism
-
10.1021/ac8022857
-
Büscher M Jr, Czernik D, Ewald JC, Sauer U, Zamboni N (2009) Cross-platform comparison of methods for quantitative metabolomics of primary metabolism. Anal Chem 81:2135
-
(2009)
Anal Chem
, vol.81
, pp. 2135
-
-
Büscher, Jr.M.1
Czernik, D.2
Ewald, J.C.3
Sauer, U.4
Zamboni, N.5
-
47
-
-
24944444149
-
Summary recommendations for standardization and reporting of metabolic analyses
-
10.1038/nbt0705-833 1:CAS:528:DC%2BD2MXlvFegsr4%3D
-
Lindon JC, Nicholson JK, Holmes E, Keun HC, Craig A, Pearce JTM, Bruce SJ, Hardy N, Sansone S-A, Antti H, Jonsson P, Daykin C, Navarange M, Beger RD, Verheij ER, Amberg A, Baunsgaard D, Cantor GH, Lehman-McKeeman L, Earll M, Wold S, Johansson E, Haselden JN, Kramer K, Thomas C, Lindberg J, Schuppe-Koistinen I, Wilson ID, Reily MD, Robertson DG, Senn H, Krotzky A, Kochhar S, Powell J, van der Ouderaa F, Plumb R, Schaefer H, Spraul M (2005) Summary recommendations for standardization and reporting of metabolic analyses. Nat Biotechnol 23:833
-
(2005)
Nat Biotechnol
, vol.23
, pp. 833
-
-
Lindon, J.C.1
Nicholson, J.K.2
Holmes, E.3
Keun, H.C.4
Craig, A.5
Pearce, J.T.M.6
Bruce, S.J.7
Hardy, N.8
Sansone, S.-A.9
Antti, H.10
Jonsson, P.11
Daykin, C.12
Navarange, M.13
Beger, R.D.14
Verheij, E.R.15
Amberg, A.16
Baunsgaard, D.17
Cantor, G.H.18
Lehman-Mckeeman, L.19
Earll, M.20
Wold, S.21
Johansson, E.22
Haselden, J.N.23
Kramer, K.24
Thomas, C.25
Lindberg, J.26
Schuppe-Koistinen, I.27
Wilson, I.D.28
Reily, M.D.29
Robertson, D.G.30
Senn, H.31
Krotzky, A.32
Kochhar, S.33
Powell, J.34
Van Der Ouderaa, F.35
Plumb, R.36
Schaefer, H.37
Spraul, M.38
more..
-
48
-
-
41749104452
-
LC-MS-based metabonomics analysis
-
10.1016/j.jchromb.2007.10.022 1:CAS:528:DC%2BD1cXkslaqurw%3D
-
Lu X, Zhao X, Bai C, Zhao C, Lu G, Xu G (2008) LC-MS-based metabonomics analysis. J Chromatogr B 866:64
-
(2008)
J Chromatogr B
, vol.866
, pp. 64
-
-
Lu, X.1
Zhao, X.2
Bai, C.3
Zhao, C.4
Lu, G.5
Xu, G.6
-
49
-
-
66349087823
-
Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics
-
10.1146/annurev.anchem.1.031207.113026 1:CAS:528:DC%2BD1cXhtFygsL7K
-
Lindon JC, Nicholson JK (2008) Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics. Annu Rev Anal Chem 1:45
-
(2008)
Annu Rev Anal Chem
, vol.1
, pp. 45
-
-
Lindon, J.C.1
Nicholson, J.K.2
-
50
-
-
79952436750
-
LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery
-
10.1021/pr101161u 1:CAS:528:DC%2BC3MXhsFamtr0%3D
-
Lin L, Huang Z, Gao Y, Yan X, Xing J, Hang W (2011) LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery. J Proteome Res 10:1396
-
(2011)
J Proteome Res
, vol.10
, pp. 1396
-
-
Lin, L.1
Huang, Z.2
Gao, Y.3
Yan, X.4
Xing, J.5
Hang, W.6
-
51
-
-
64549133864
-
Metabolomic characterization of human rectal adenocarcinoma with intact tissue magnetic resonance spectroscopy
-
10.1007/DCR.0b013e31819c9a2c
-
Jordan KW, Nordenstam J, Lauwers GY, Rothenberger DA, Alavi K, Garwood M, Cheng LL (2009) Metabolomic characterization of human rectal adenocarcinoma with intact tissue magnetic resonance spectroscopy. Dis Colon Rectum 52:520
-
(2009)
Dis Colon Rectum
, vol.52
, pp. 520
-
-
Jordan, K.W.1
Nordenstam, J.2
Lauwers, G.Y.3
Rothenberger, D.A.4
Alavi, K.5
Garwood, M.6
Cheng, L.L.7
-
52
-
-
65249160227
-
Discrimination of healthy and neoplastic human colon tissues by ex vivo HR-MAS NMR spectroscopy and chemometric analyses
-
10.1021/pr801094b 1:CAS:528:DC%2BD1MXislagsLw%3D
-
Righi V, Durante C, Cocchi M, Calabrese C, Di Febo G, Lecce F, Pisi A, Tugnoli V, Mucci A, Schenetti L (2009) Discrimination of healthy and neoplastic human colon tissues by ex vivo HR-MAS NMR spectroscopy and chemometric analyses. J Proteome Res 8:1859
-
(2009)
J Proteome Res
, vol.8
, pp. 1859
-
-
Righi, V.1
Durante, C.2
Cocchi, M.3
Calabrese, C.4
Di Febo, G.5
Lecce, F.6
Pisi, A.7
Tugnoli, V.8
Mucci, A.9
Schenetti, L.10
-
53
-
-
0030083090
-
Quantitative and qualitative characterization of 1H NMR spectra of colon tumors, normal mucosa and their perchloric acid extracts: Decreased levels of myo-inositol in tumours can be detected in intact biopsies
-
10.1002/(SICI)1099-1492(199602)9:1<33: AID-NBM391>3.0.CO;2-G 1:CAS:528:DyaK28XltFWis7k%3D
-
Moreno A, Arús C (1996) Quantitative and qualitative characterization of 1H NMR spectra of colon tumors, normal mucosa and their perchloric acid extracts: decreased levels of myo-inositol in tumours can be detected in intact biopsies. NMR Biomed 9:33
-
(1996)
NMR Biomed
, vol.9
, pp. 33
-
-
Moreno, A.1
Arús, C.2
-
54
-
-
77949822339
-
Urinary metabonomic study on colorectal cancer
-
10.1021/pr901081y 1:CAS:528:DC%2BC3cXitV2hs70%3D
-
Qiu Y, Cai G, Su M, Chen T, Liu Y, Xu Y, Ni Y, Zhao A, Cai S, Xu LX, Jia W (2010) Urinary metabonomic study on colorectal cancer. J Proteome Res 9:1627
-
(2010)
J Proteome Res
, vol.9
, pp. 1627
-
-
Qiu, Y.1
Cai, G.2
Su, M.3
Chen, T.4
Liu, Y.5
Xu, Y.6
Ni, Y.7
Zhao, A.8
Cai, S.9
Xu, L.X.10
Jia, W.11
-
55
-
-
0035870164
-
Evaluation of opiate separation by high-resolution electrospray ionization-ion mobility spectrometry/mass spectrometry
-
10.1021/ac001147b 1:CAS:528:DC%2BD3MXhslSrsb0%3D
-
Matz LM, Hill HH (2001) Evaluation of opiate separation by high-resolution electrospray ionization-ion mobility spectrometry/mass spectrometry. Anal Chem 73:1664
-
(2001)
Anal Chem
, vol.73
, pp. 1664
-
-
Matz, L.M.1
Hill, H.H.2
-
56
-
-
78349308282
-
Metabolic profiling of human blood by high-resolution ion mobility mass spectrometry (IM-MS)
-
10.1016/j.ijms.2010.02.007 1:CAS:528:DC%2BC3cXhsVWqtLfN
-
Dwivedi P, Schultz AJ Jr, Hill HH (2010) Metabolic profiling of human blood by high-resolution ion mobility mass spectrometry (IM-MS). Int J Mass Spectrom 298:78
-
(2010)
Int J Mass Spectrom
, vol.298
, pp. 78
-
-
Dwivedi, P.1
Schultz, Jr.A.J.2
Hill, H.H.3
-
57
-
-
78349309108
-
A rapid analytical method for hair analysis using ambient pressure ion mobility mass spectrometry with electrospray ionization (ESI-IMMS)
-
10.1007/s12127-008-0006-5 1:CAS:528:DC%2BD1MXjsVKktrw%3D
-
Dwivedi P, Hill HH (2008) A rapid analytical method for hair analysis using ambient pressure ion mobility mass spectrometry with electrospray ionization (ESI-IMMS). Int J Ion Mobil Spectrom 11:61
-
(2008)
Int J Ion Mobil Spectrom
, vol.11
, pp. 61
-
-
Dwivedi, P.1
Hill, H.H.2
-
58
-
-
38949210993
-
Metabolic profiling by ion mobility mass spectrometry (IMMS)
-
10.1007/s11306-007-0093-z 1:CAS:528:DC%2BD1cXisFSmtL4%3D
-
Dwivedi P, Wu P, Klopsch SJ, Puzon GJ, Xun L, Hill HH (2008) Metabolic profiling by ion mobility mass spectrometry (IMMS). Metabolomics 4:63
-
(2008)
Metabolomics
, vol.4
, pp. 63
-
-
Dwivedi, P.1
Wu, P.2
Klopsch, S.J.3
Puzon, G.J.4
Xun, L.5
Hill, H.H.6
-
59
-
-
70349629998
-
Monitoring dynamic changes in lymph metabolome of fasting and fed rats by electrospray ionization-ion mobility mass spectrometry (ESI-IMMS)
-
10.1021/ac901030k 1:CAS:528:DC%2BD1MXhtVKgsL7P
-
Kaplan K, Dwivedi P, Davidson S, Yang Q, Tso P, Siems W, Hill HH (2009) Monitoring dynamic changes in lymph metabolome of fasting and fed rats by electrospray ionization-ion mobility mass spectrometry (ESI-IMMS). Anal Chem 81:7944
-
(2009)
Anal Chem
, vol.81
, pp. 7944
-
-
Kaplan, K.1
Dwivedi, P.2
Davidson, S.3
Yang, Q.4
Tso, P.5
Siems, W.6
Hill, H.H.7
-
60
-
-
82355182101
-
Metabolic differences among melanoma and two prostate cancer cell lines by electrospray ion mobility mass spectrometry
-
10.1007/s12127-011-0066-9 1:CAS:528:DC%2BC3MXhsFKrsb3O
-
Kaplan K, Liu X, Fu Y-M, Lin H, Meadows GG, Siems W, Hill HH (2011) Metabolic differences among melanoma and two prostate cancer cell lines by electrospray ion mobility mass spectrometry. Int J Ion Mobil Spectrom 14:151
-
(2011)
Int J Ion Mobil Spectrom
, vol.14
, pp. 151
-
-
Kaplan, K.1
Liu, X.2
Fu, Y.-M.3
Lin, H.4
Meadows, G.G.5
Siems, W.6
Hill, H.H.7
-
61
-
-
79960384696
-
Mass spectrometry strategies in metabolomics
-
10.1074/jbc.R111.238691 1:CAS:528:DC%2BC3MXovFCksbY%3D
-
Lei Z, Huhman DV, Sumner LW (2011) Mass spectrometry strategies in metabolomics. J Biol Chem 286:25435
-
(2011)
J Biol Chem
, vol.286
, pp. 25435
-
-
Lei, Z.1
Huhman, D.V.2
Sumner, L.W.3
-
62
-
-
41049096359
-
Quantitative metabolomics using NMR
-
10.1016/j.trac.2007.12.001 1:CAS:528:DC%2BD1cXjvF2jtLg%3D
-
Wishart DS (2008) Quantitative metabolomics using NMR. Trends Anal Chem 27:228
-
(2008)
Trends Anal Chem
, vol.27
, pp. 228
-
-
Wishart, D.S.1
-
63
-
-
0036201397
-
Human rectal adenocarcinoma: Demonstration of1H-MR spectra in vivo at 1.5 T
-
10.1002/mrm.10108 1:STN:280:DC%2BD383htFCjtw%3D%3D
-
Dzik-Jurasz ASK, Murphy PS, George M, Prock T, Collins DJ, Swift I, Leach MO, Rowland IJ (2002) Human rectal adenocarcinoma: demonstration of1H-MR spectra in vivo at 1.5 T. Magn Reson Med 47:809
-
(2002)
Magn Reson Med
, vol.47
, pp. 809
-
-
Dzik-Jurasz, A.S.K.1
Murphy, P.S.2
George, M.3
Prock, T.4
Collins, D.J.5
Swift, I.6
Leach, M.O.7
Rowland, I.J.8
-
64
-
-
35648974374
-
Topographical variation in metabolic signatures of human gastrointestinal biopsies revealed by high-resolution magic-angle spinning 1H NMR spectroscopy
-
10.1021/pr0702565 1:CAS:528:DC%2BD2sXpt1GitLo%3D
-
Wang Y, Holmes E, Comelli EM, Fotopoulos G, Dorta G, Tang H, Rantalainen MJ, Lindon JC, Corthésy-Theulaz IE, Fay LB, Kochhar S, Nicholson JK (2007) Topographical variation in metabolic signatures of human gastrointestinal biopsies revealed by high-resolution magic-angle spinning 1H NMR spectroscopy. J Proteome Res 6:3944
-
(2007)
J Proteome Res
, vol.6
, pp. 3944
-
-
Wang, Y.1
Holmes, E.2
Comelli, E.M.3
Fotopoulos, G.4
Dorta, G.5
Tang, H.6
Rantalainen, M.J.7
Lindon, J.C.8
Corthésy-Theulaz, I.E.9
Fay, L.B.10
Kochhar, S.11
Nicholson, J.K.12
-
65
-
-
0027565016
-
1H NMR spectroscopy of colon tumors and normal mucosal biopsies; Elevated taurine levels and reduced polyethyleneglycol absorption in tumors may have diagnostic significance
-
10.1002/nbm.1940060202 1:STN:280:DyaK3s3ntV2gsA%3D%3D
-
Moreno A, Rey M, Montane JM, Alonso J, Arús C (1993) 1H NMR spectroscopy of colon tumors and normal mucosal biopsies; elevated taurine levels and reduced polyethyleneglycol absorption in tumors may have diagnostic significance. NMR Biomed 6:111
-
(1993)
NMR Biomed
, vol.6
, pp. 111
-
-
Moreno, A.1
Rey, M.2
Montane, J.M.3
Alonso, J.4
Arús, C.5
-
66
-
-
0025824182
-
Phospholipid profiles of human colon cancer using 31P magnetic resonance spectroscopy
-
10.1007/BF00300208 1:STN:280:DyaK3MzktFemsA%3D%3D
-
Merchant TE, Kasimos JN, de Graaf PW, Minsky BD, Gierke LW, Glonek T (1991) Phospholipid profiles of human colon cancer using 31P magnetic resonance spectroscopy. Int J Colorectal Dis 6:121
-
(1991)
Int J Colorectal Dis
, vol.6
, pp. 121
-
-
Merchant, T.E.1
Kasimos, J.N.2
De Graaf, P.W.3
Minsky, B.D.4
Gierke, L.W.5
Glonek, T.6
-
67
-
-
0026647357
-
Phosphodiesters in saponified extracts of human breast and colon tumors using 31P magnetic resonance spectroscopy
-
10.1002/mrm.1910260114 1:STN:280:DyaK38zis1Gqug%3D%3D
-
Merchant TE, Characiejus D, Kasimos JN, Den Otter W, Gierke LW, Glonek T (1992) Phosphodiesters in saponified extracts of human breast and colon tumors using 31P magnetic resonance spectroscopy. Magn Reson Med 26:132
-
(1992)
Magn Reson Med
, vol.26
, pp. 132
-
-
Merchant, T.E.1
Characiejus, D.2
Kasimos, J.N.3
Den Otter, W.4
Gierke, L.W.5
Glonek, T.6
-
68
-
-
0025917909
-
Fucose in 1H COSY spectra of plasma membrane fragments shed from human malignant colorectal cells
-
10.1002/mrm.1910200213 1:CAS:528:DyaK38Xhsl2jsA%3D%3D
-
Lean CL, Mackinnon WB, Mountford CE (1991) Fucose in 1H COSY spectra of plasma membrane fragments shed from human malignant colorectal cells. Magn Reson Med 20:306
-
(1991)
Magn Reson Med
, vol.20
, pp. 306
-
-
Lean, C.L.1
Mackinnon, W.B.2
Mountford, C.E.3
-
69
-
-
0024425881
-
Metabolic changes in undifferentiated and differentiated human colon adenocarcinoma cells studied by multinuclear magnetic resonance spectroscopy
-
10.1016/0300-9084(89)90077-1 1:CAS:528:DyaL1MXmt12ksbg%3D
-
Galons JP, Fantini J, Vion-Dury J, Cozzone PJ, Canioni P (1989) Metabolic changes in undifferentiated and differentiated human colon adenocarcinoma cells studied by multinuclear magnetic resonance spectroscopy. Biochimie 71:949
-
(1989)
Biochimie
, vol.71
, pp. 949
-
-
Galons, J.P.1
Fantini, J.2
Vion-Dury, J.3
Cozzone, P.J.4
Canioni, P.5
-
70
-
-
0025192241
-
31P magnetic resonance spectroscopy of human colon cancer
-
1:CAS:528:DyaK3cXhtlKksL4%3D
-
Kasimos JN, Merchant TE, Gierke LW, Glonek T (1990) 31P magnetic resonance spectroscopy of human colon cancer. Cancer Res 50:527
-
(1990)
Cancer Res
, vol.50
, pp. 527
-
-
Kasimos, J.N.1
Merchant, T.E.2
Gierke, L.W.3
Glonek, T.4
-
71
-
-
0026606164
-
Polyamine levels, ornithine decarboxylase (ODC) activity, and ODC-mRNA expression in normal and cancerous human colonocytes
-
10.1016/0024-3205(92)90260-V 1:CAS:528:DyaK38XitFajurc%3D
-
Elitsur Y, Moshier JA, Murthy R, Barbish A, Luk GD (1992) Polyamine levels, ornithine decarboxylase (ODC) activity, and ODC-mRNA expression in normal and cancerous human colonocytes. Life Sci 50:1417
-
(1992)
Life Sci
, vol.50
, pp. 1417
-
-
Elitsur, Y.1
Moshier, J.A.2
Murthy, R.3
Barbish, A.4
Luk, G.D.5
-
72
-
-
0021143773
-
Polyamines in colorectal cancer
-
10.1002/bjs.1800711019 1:STN:280:DyaL2M%2FisVSnsg%3D%3D
-
Kingsnorth AN, Lumsden AB, Wallace HM (1984) Polyamines in colorectal cancer. Br J Surg 71:791
-
(1984)
Br J Surg
, vol.71
, pp. 791
-
-
Kingsnorth, A.N.1
Lumsden, A.B.2
Wallace, H.M.3
-
73
-
-
0141593748
-
Screening of biomarkers in rat urine using LC/electrospray ionization-MS and two-way data analysis
-
10.1021/ac0341618
-
Idborg-Björkman H, Edlund P-O, Kvalheim OM, Schuppe-Koistinen I, Jacobsson SP (2003) Screening of biomarkers in rat urine using LC/electrospray ionization-MS and two-way data analysis. Anal Chem 75:4784
-
(2003)
Anal Chem
, vol.75
, pp. 4784
-
-
Idborg-Björkman, H.1
Edlund, P.-O.2
Kvalheim, O.M.3
Schuppe-Koistinen, I.4
Jacobsson, S.P.5
-
74
-
-
0142258161
-
Bioanalytical liquid chromatography tandem mass spectrometry methods on underivatized silica columns with aqueous/organic mobile phases
-
10.1016/j.jchromb.2003.08.026 1:CAS:528:DC%2BD3sXosVyisb4%3D
-
Naidong W (2003) Bioanalytical liquid chromatography tandem mass spectrometry methods on underivatized silica columns with aqueous/organic mobile phases. J Chromatogr B 796:209
-
(2003)
J Chromatogr B
, vol.796
, pp. 209
-
-
Naidong, W.1
-
75
-
-
17444404226
-
High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies
-
10.1021/pr049769r 1:CAS:528:DC%2BD2MXisV2js7g%3D
-
Wilson ID, Nicholson JK, Castro-Perez J, Granger JH, Johnson KA, Smith BW, Plumb RS (2005) High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. J Proteome Res 4:591
-
(2005)
J Proteome Res
, vol.4
, pp. 591
-
-
Wilson, I.D.1
Nicholson, J.K.2
Castro-Perez, J.3
Granger, J.H.4
Johnson, K.A.5
Smith, B.W.6
Plumb, R.S.7
-
76
-
-
33646743247
-
Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: Quantitative analysis of endogenous and exogenous metabolites in human serum
-
10.1021/ac060245f
-
Nordström A, O'Maille G, Qin C, Siuzdak G (2006) Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum. Anal Chem 78:3289
-
(2006)
Anal Chem
, vol.78
, pp. 3289
-
-
Nordström, A.1
O'Maille, G.2
Qin, C.3
Siuzdak, G.4
-
77
-
-
33646123072
-
Capillary electrophoresis in metabolomics
-
10.1016/j.trac.2006.02.004 1:CAS:528:DC%2BD28Xkt1yjtrk%3D
-
Ramautar R, Demirci A, Jong GJD (2006) Capillary electrophoresis in metabolomics. Trends Anal Chem 25:455
-
(2006)
Trends Anal Chem
, vol.25
, pp. 455
-
-
Ramautar, R.1
Demirci, A.2
Jong, G.J.D.3
-
78
-
-
34748879347
-
Metabolome analysis by capillary electrophoresis-mass spectrometry
-
10.1016/j.chroma.2007.02.065 1:CAS:528:DC%2BD2sXhtFeqtrvJ
-
Monton MRN, Soga T (2007) Metabolome analysis by capillary electrophoresis-mass spectrometry. J Chromatogr A 1168:237
-
(2007)
J Chromatogr A
, vol.1168
, pp. 237
-
-
Monton, M.R.N.1
Soga, T.2
-
79
-
-
33947724376
-
Design and performance of an atmospheric pressure ion mobility Fourier transform ion cyclotron resonance mass spectrometer
-
10.1002/rcm.2928 1:CAS:528:DC%2BD2sXks1Grt7w%3D
-
Tang X, Bruce JE, Hill HH (2007) Design and performance of an atmospheric pressure ion mobility Fourier transform ion cyclotron resonance mass spectrometer. Rapid Commun Mass Spectrom 21:1115
-
(2007)
Rapid Commun Mass Spectrom
, vol.21
, pp. 1115
-
-
Tang, X.1
Bruce, J.E.2
Hill, H.H.3
-
80
-
-
23844466290
-
Multidimensional separations of ubiquitin conformers in the gas phase: Relating ion cross sections to H/D exchange measurements
-
10.1016/j.jasms.2005.04.007 1:CAS:528:DC%2BD2MXpt1Wnur0%3D
-
Robinson EW, Williams ER (2005) Multidimensional separations of ubiquitin conformers in the gas phase: relating ion cross sections to H/D exchange measurements. J Am Soc Mass Spectrom 16:1427
-
(2005)
J Am Soc Mass Spectrom
, vol.16
, pp. 1427
-
-
Robinson, E.W.1
Williams, E.R.2
-
81
-
-
0033556190
-
ESI/ion trap/ion mobility/time-of-flight mass spectrometry for rapid and sensitive analysis of biomolecular mixtures
-
10.1021/ac9809175 1:CAS:528:DyaK1cXnslOhtrc%3D
-
Henderson SC, Valentine SJ, Counterman AE, Clemmer DE (1999) ESI/ion trap/ion mobility/time-of-flight mass spectrometry for rapid and sensitive analysis of biomolecular mixtures. Anal Chem 71:291
-
(1999)
Anal Chem
, vol.71
, pp. 291
-
-
Henderson, S.C.1
Valentine, S.J.2
Counterman, A.E.3
Clemmer, D.E.4
-
82
-
-
1942423075
-
Lipid/peptide/nucleotide separation with MALDI-ion mobility-TOF MS
-
10.1021/ac035376k 1:CAS:528:DC%2BD2cXitFOrur4%3D
-
Woods AS, Ugarov M, Egan T, Koomen J, Gillig KJ, Fuhrer K, Gonin M, Schultz JA (2004) Lipid/peptide/nucleotide separation with MALDI-ion mobility-TOF MS. Anal Chem 76:2187
-
(2004)
Anal Chem
, vol.76
, pp. 2187
-
-
Woods, A.S.1
Ugarov, M.2
Egan, T.3
Koomen, J.4
Gillig, K.J.5
Fuhrer, K.6
Gonin, M.7
Schultz, J.A.8
-
83
-
-
33744966379
-
IR-MALDI-LDI combined with ion mobility orthogonal time-of-flight mass spectrometry
-
10.1021/pr060055l 1:CAS:528:DC%2BD28XksFyqsLY%3D
-
Woods AS, Ugarov M, Jackson SN, Egan T, Wang H-YJ, Murray KK, Schultz JA (2006) IR-MALDI-LDI combined with ion mobility orthogonal time-of-flight mass spectrometry. J Proteome Res 5:1484
-
(2006)
J Proteome Res
, vol.5
, pp. 1484
-
-
Woods, A.S.1
Ugarov, M.2
Jackson, S.N.3
Egan, T.4
Wang, H.-Y.5
Murray, K.K.6
Schultz, J.A.7
-
84
-
-
38949210993
-
-
Dwivedi P, Wu P, Klopsch S, Puzon G, Xun L, Hill H (2008) Metabolic profiling by ion mobility mass spectrometry (IMMS) 4:63
-
(2008)
Metabolic Profiling by Ion Mobility Mass Spectrometry (IMMS)
, vol.4
, pp. 63
-
-
Dwivedi, P.1
Wu, P.2
Klopsch, S.3
Puzon, G.4
Xun, L.5
Hill, H.6
-
85
-
-
33645523088
-
Influence of cation adduction on the separation characteristics of flavonoid diglycoside isomers using dual gate-ion mobility-quadrupole ion trap mass spectrometry
-
10.1002/jms.994 1:CAS:528:DC%2BD28Xjs1Snu7Y%3D
-
Clowers BH, Hill HH (2006) Influence of cation adduction on the separation characteristics of flavonoid diglycoside isomers using dual gate-ion mobility-quadrupole ion trap mass spectrometry. J Mass Spectrom 41:339
-
(2006)
J Mass Spectrom
, vol.41
, pp. 339
-
-
Clowers, B.H.1
Hill, H.H.2
-
86
-
-
26444441382
-
Two-dimensional gas-phase separations coupled to mass spectrometry for analysis of complex mixtures
-
10.1021/ac050871x 1:CAS:528:DC%2BD2MXosVGhu7o%3D
-
Tang K, Li F, Shvartsburg AA, Strittmatter EF, Smith RD (2005) Two-dimensional gas-phase separations coupled to mass spectrometry for analysis of complex mixtures. Anal Chem 77:6381
-
(2005)
Anal Chem
, vol.77
, pp. 6381
-
-
Tang, K.1
Li, F.2
Shvartsburg, A.A.3
Strittmatter, E.F.4
Smith, R.D.5
-
87
-
-
28844474910
-
Evidence for macromolecular protein rings in the absence of bulk water
-
10.1126/science.1120177 1:CAS:528:DC%2BD2MXhtlSntLfE
-
Ruotolo BT (2005) Evidence for macromolecular protein rings in the absence of bulk water. Science 310:1658
-
(2005)
Science
, vol.310
, pp. 1658
-
-
Ruotolo, B.T.1
-
88
-
-
33846217403
-
Assessing the peak capacity of IMS-IMS separations of tryptic peptide ions in He at 300 K
-
10.1021/ac061567m 1:CAS:528:DC%2BD28Xht1Ghs7nK
-
Merenbloom SI, Bohrer BC, Koeniger SL, Clemmer DE (2007) Assessing the peak capacity of IMS-IMS separations of tryptic peptide ions in He at 300 K. Anal Chem 79:515
-
(2007)
Anal Chem
, vol.79
, pp. 515
-
-
Merenbloom, S.I.1
Bohrer, B.C.2
Koeniger, S.L.3
Clemmer, D.E.4
-
89
-
-
0002535068
-
Detection of the picolinic acid biomarker in Bacillus spores using a potentially field-portable pyrolysis - Gas chromatography - Ion mobility spectrometry system
-
10.1002/(SICI)1520-6521(1996)1:1<49: AID-FACT7>3.0.CO;2-9 1:CAS:528:DyaK28Xms1Okurw%3D
-
Snyder AP, Thornton SN, Dworzanski JP, Meuzelaar HLC (1996) Detection of the picolinic acid biomarker in Bacillus spores using a potentially field-portable pyrolysis - gas chromatography - ion mobility spectrometry system. Field Anal Chem Technol 1:49
-
(1996)
Field Anal Chem Technol
, vol.1
, pp. 49
-
-
Snyder, A.P.1
Thornton, S.N.2
Dworzanski, J.P.3
Meuzelaar, H.L.C.4
-
90
-
-
0035891934
-
Multidimensional separations of complex peptide mixtures: A combined high-performance liquid chromatography/ion mobility/time-of-flight mass spectrometry approach
-
10.1016/S1387-3806(01)00511-5 1:CAS:528:DC%2BD38XisVyg
-
Valentine SJ, Kulchania M, Barnes CAS, Clemmer DE (2001) Multidimensional separations of complex peptide mixtures: a combined high-performance liquid chromatography/ion mobility/time-of-flight mass spectrometry approach. Int J Mass Spectrom 212:97
-
(2001)
Int J Mass Spectrom
, vol.212
, pp. 97
-
-
Valentine, S.J.1
Kulchania, M.2
Barnes, C.A.S.3
Clemmer, D.E.4
-
91
-
-
84856849289
-
Cancer metabolism: Current perspectives and future directions
-
Muñoz-Pinedo C, El Mjiyad N, Ricci JE (2012) Cancer metabolism: current perspectives and future directions. Cell Death Dis 3
-
(2012)
Cell Death Dis
, pp. 3
-
-
Muñoz-Pinedo C, E.1
-
92
-
-
5444250387
-
Applications of a travelling wave-based radio-frequency-only stacked ring ion guide
-
10.1002/rcm.1641 1:CAS:528:DC%2BD2cXptVSjsr8%3D
-
Giles K, Pringle SD, Worthington KR, Little D, Wildgoose JL, Bateman RH (2004) Applications of a travelling wave-based radio-frequency-only stacked ring ion guide. Rapid Commun Mass Spectrom 18:2401
-
(2004)
Rapid Commun Mass Spectrom
, vol.18
, pp. 2401
-
-
Giles, K.1
Pringle, S.D.2
Worthington, K.R.3
Little, D.4
Wildgoose, J.L.5
Bateman, R.H.6
-
93
-
-
84859376734
-
Resolving structural isomers of monosaccharide methyl glycosides using drift tube and traveling wave ion mobility mass spectrometry
-
Li H, Giles K, Bendiak B, Kaplan K, Siems WF, Hill HH (2012) Resolving structural isomers of monosaccharide methyl glycosides using drift tube and traveling wave ion mobility mass spectrometry. Anal Chem 84(7):3231-3239
-
(2012)
Anal Chem
, vol.84
, Issue.7
, pp. 3231-3239
-
-
Li, H.1
Giles, K.2
Bendiak, B.3
Kaplan, K.4
Siems, W.F.5
Hill, H.H.6
-
94
-
-
71949083077
-
Metabolomics profiling of extracellular metabolites in recombinant Chinese hamster ovary fed-batch culture
-
10.1002/rcm.4328 1:CAS:528:DC%2BD1MXhsVahur3I
-
Chong WPK, Goh LT, Reddy SG, Yusufi FNK, Lee DY, Wong NSC, Heng CK, Yap MGS, Ho YS (2009) Metabolomics profiling of extracellular metabolites in recombinant Chinese hamster ovary fed-batch culture. Rapid Commun Mass Spectrom 23:3763
-
(2009)
Rapid Commun Mass Spectrom
, vol.23
, pp. 3763
-
-
Chong, W.P.K.1
Goh, L.T.2
Reddy, S.G.3
Yusufi, F.N.K.4
Lee, D.Y.5
Wong, N.S.C.6
Heng, C.K.7
Yap, M.G.S.8
Ho, Y.S.9
-
95
-
-
80053926087
-
A comprehensive untargeted metabonomic analysis of human steatotic liver tissue by RP and HILIC chromatography coupled to mass spectrometry reveals important metabolic alterations
-
10.1021/pr200629p
-
García-Cañaveras JC, Donato MT, Castell JV, Lahoz A (2011) A comprehensive untargeted metabonomic analysis of human steatotic liver tissue by RP and HILIC chromatography coupled to mass spectrometry reveals important metabolic alterations. J Proteome Res 10:4825
-
(2011)
J Proteome Res
, vol.10
, pp. 4825
-
-
García-Cañaveras, J.C.1
Donato, M.T.2
Castell, J.V.3
Lahoz, A.4
-
96
-
-
84856231790
-
Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS)
-
10.1007/s00216-011-5556-4
-
Paglia G, Hrafnsdóttir S, Magnúsdóttir M, Fleming RMT, Thorlacius S, Palsson BØ, Thiele I (2011) Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS). Anal Bioanal Chem 402:1183
-
(2011)
Anal Bioanal Chem
, vol.402
, pp. 1183
-
-
Paglia, G.1
Hrafnsdóttir, S.2
Magnúsdóttir, M.3
Fleming, R.M.T.4
Thorlacius, S.5
Palsson, BØ.6
Thiele, I.7
-
97
-
-
84863258933
-
Ingenuity pathways analysis of urine metabolomics phenotypes toxicity of Chuanwu in Wistar rats by UPLC-Q-TOF-HDMS coupled with pattern recognition methods
-
Dong H, Zhang A, Sun H, Wang H, Lu X, Wang M, Ni B, Wang X (2012) Ingenuity pathways analysis of urine metabolomics phenotypes toxicity of Chuanwu in Wistar rats by UPLC-Q-TOF-HDMS coupled with pattern recognition methods. Mol Biosyst 8
-
(2012)
Mol Biosyst
, pp. 8
-
-
Dong, H.1
Zhang, A.2
Sun, H.3
Wang, H.4
Lu, X.5
Wang, M.6
Ni, B.7
Wang, X.8
-
98
-
-
0035904395
-
Molecular biology of HMGA proteins: Hubs of nuclear function
-
10.1016/S0378-1119(01)00689-8 1:CAS:528:DC%2BD3MXnsFGgtb4%3D
-
Reeves R (2001) Molecular biology of HMGA proteins: hubs of nuclear function. Gene 277:63
-
(2001)
Gene
, vol.277
, pp. 63
-
-
Reeves, R.1
-
99
-
-
76549100402
-
The high mobility group A1 gene: Transforming inflammatory signals into cancer?
-
10.1158/0008-5472.CAN-09-1212 1:CAS:528:DC%2BC3cXltlWksw%3D%3D
-
Resar LMS (2010) The high mobility group A1 gene: transforming inflammatory signals into cancer? Cancer Res 70:436
-
(2010)
Cancer Res
, vol.70
, pp. 436
-
-
Resar, L.M.S.1
-
100
-
-
84856055494
-
HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells
-
Belton A, Gabrovsky A, Bae YK, Reeves R, Iacobuzio-Donahue C, Huso DL, Resar LMS (2012) HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells. PLoS ONE 7
-
(2012)
PLoS ONE
, pp. 7
-
-
Belton, A.1
Gabrovsky, A.2
Bae, Y.K.3
Reeves, R.4
Iacobuzio-Donahue, C.5
Huso, D.L.6
Resar, L.M.S.7
-
101
-
-
0026101592
-
Ornithine decarboxylase activity and polyamine content in adenocarcinomas of human stomach and large intestine
-
10.1002/ijc.2910470404 1:STN:280:DyaK3M7jvFalsg%3D%3D
-
Berdinskikh NK, Ignatenko NA, Zaletok SP, Ganina KP, Chorniy VA (1991) Ornithine decarboxylase activity and polyamine content in adenocarcinomas of human stomach and large intestine. J Int Cancer 47:496
-
(1991)
J Int Cancer
, vol.47
, pp. 496
-
-
Berdinskikh, N.K.1
Ignatenko, N.A.2
Zaletok, S.P.3
Ganina, K.P.4
Chorniy, V.A.5
-
102
-
-
0025758288
-
Decreased levels of 1,2-sn-diacylglycerol in human colon tumors
-
1:STN:280:DyaK3M7ksF2itg%3D%3D
-
Phan SC, Morotomi M, Guillem JG, LoGerfo P, Weinstein IB (1991) Decreased levels of 1,2-sn-diacylglycerol in human colon tumors. Cancer Res 51:1571
-
(1991)
Cancer Res
, vol.51
, pp. 1571
-
-
Phan, S.C.1
Morotomi, M.2
Guillem, J.G.3
Logerfo, P.4
Weinstein, I.B.5
-
103
-
-
57449087215
-
Is cancer a disease of abnormal cellular metabolism? New angles on an old idea
-
10.1097/GIM.0b013e31818b0d9b 1:CAS:528:DC%2BD1cXhtlyksrvN
-
Deberardinis RJ (2008) Is cancer a disease of abnormal cellular metabolism? New angles on an old idea. Genet Med 10:767
-
(2008)
Genet Med
, vol.10
, pp. 767
-
-
Deberardinis, R.J.1
-
104
-
-
0030848314
-
Human argininosuccinate lyase: A structural basis for intragenic complementation
-
10.1073/pnas.94.17.9063 1:CAS:528:DyaK2sXls1KmurY%3D
-
Turner MA, Simpson A, McInnes RR, Howell PL (1997) Human argininosuccinate lyase: a structural basis for intragenic complementation. Proc Natl Acad Sci USA 94:9063
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9063
-
-
Turner, M.A.1
Simpson, A.2
McInnes, R.R.3
Howell, P.L.4
-
105
-
-
79952741730
-
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
-
10.1073/pnas.1019393108 1:CAS:528:DC%2BC3MXislGhtLc%3D
-
Reitman ZJ, Jin G, Karoly ED, Spasojevic I, Yang J, Kinzler KW, He Y, Bigner DD, Vogelstein B, Yan H (2011) Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proc Natl Acad Sci USA 108:3270
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3270
-
-
Reitman, Z.J.1
Jin, G.2
Karoly, E.D.3
Spasojevic, I.4
Yang, J.5
Kinzler, K.W.6
He, Y.7
Bigner, D.D.8
Vogelstein, B.9
Yan, H.10
-
106
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
10.1038/nature08617 1:CAS:528:DC%2BD1MXhsVGlurzE
-
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, Rabinowitz JD, Cantley LC, Thompson CB, Vander Heiden MG, Su SM (2009) Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462:739
-
(2009)
Nature
, vol.462
, pp. 739
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
Fantin, V.R.7
Jang, H.G.8
Jin, S.9
Keenan, M.C.10
Marks, K.M.11
Prins, R.M.12
Ward, P.S.13
Yen, K.E.14
Liau, L.M.15
Rabinowitz, J.D.16
Cantley, L.C.17
Thompson, C.B.18
Vander Heiden, M.G.19
Su, S.M.20
more..
-
107
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
-
10.1016/j.ccr.2010.12.014 1:CAS:528:DC%2BC3MXpvValsQ%3D%3D
-
Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim S-H, Ito S, Yang C, Wang P, Xiao M-T (2011) Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell 19:17
-
(2011)
Cancer Cell
, vol.19
, pp. 17
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
Yang, Y.4
Wang, P.5
Kim, S.-H.6
Ito, S.7
Yang, C.8
Wang, P.9
Xiao, M.-T.10
-
108
-
-
79955518028
-
Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression
-
10.1158/0008-5472.CAN-10-3894 1:CAS:528:DC%2BC3MXltlGhtb8%3D
-
Hilvo M, Denkert C, Lehtinen L, Muller B, Brockmoller S, Seppanen-Laakso T, Budczies J, Bucher E, Yetukuri L, Castillo S, Berg E, Nygren H, Sysi-Aho M, Griffin JL, Fiehn O, Loibl S, Richter-Ehrenstein C, Radke C, Hyotylainen T, Kallioniemi O, Iljin K, Oresic M (2011) Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression. Cancer Res 71:3236
-
(2011)
Cancer Res
, vol.71
, pp. 3236
-
-
Hilvo, M.1
Denkert, C.2
Lehtinen, L.3
Muller, B.4
Brockmoller, S.5
Seppanen-Laakso, T.6
Budczies, J.7
Bucher, E.8
Yetukuri, L.9
Castillo, S.10
Berg, E.11
Nygren, H.12
Sysi-Aho, M.13
Griffin, J.L.14
Fiehn, O.15
Loibl, S.16
Richter-Ehrenstein, C.17
Radke, C.18
Hyotylainen, T.19
Kallioniemi, O.20
Iljin, K.21
Oresic, M.22
more..
-
109
-
-
84856663324
-
Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer - Link to patient survival, hormone receptor status, and metabolic profiling
-
10.1021/pr200685r
-
Brockmöller SF, Bucher E, Müller BM, Budczies J, Hilvo M, Griffin JL, Orešič M, Kallioniemi O, Iljin K, Loibl S, Darb-Esfahani S, Sinn BV, Klauschen F, Prinzler J, Bangemann N, Ismaeel F, Fiehn O, Dietel M, Denkert C (2012) Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer - link to patient survival, hormone receptor status, and metabolic profiling. J Proteome Res 11:850
-
(2012)
J Proteome Res
, vol.11
, pp. 850
-
-
Brockmöller, S.F.1
Bucher, E.2
Müller, B.M.3
Budczies, J.4
Hilvo, M.5
Griffin, J.L.6
Orešič, M.7
Kallioniemi, O.8
Iljin, K.9
Loibl, S.10
Darb-Esfahani, S.11
Sinn, B.V.12
Klauschen, F.13
Prinzler, J.14
Bangemann, N.15
Ismaeel, F.16
Fiehn, O.17
Dietel, M.18
Denkert, C.19
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