Stereochemistry of reductions catalyzed by methyl-epimerizing ketoreductase domains of polyketide synthases

Journal of the American Chemical Society

Volumn 135, Issue 20, 2013, Pages 7406-7409

  You, Young Ok ^a   Khosla, Chaitan ^b   Cane, David E ^a  

^a BROWN UNIVERSITY   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEINS; CHEMO-ENZYMATIC SYNTHESIS; GC-MS ANALYSIS; POLYKETIDE BIOSYNTHESIS; POLYKETIDE SYNTHASES; PRODUCT STRUCTURE; PROTEIN SEQUENCES; STEREOSPECIFICITY;

BIOCHEMISTRY; FUNCTIONAL GROUPS; KETONES; RECOMBINANT PROTEINS; STEREOCHEMISTRY;

CATALYSIS;

2 METHYL 3 KETOACYL ACYL CARRIER PROTEIN; CARRIER PROTEIN; KETOREDUCTASE; NYSTATIN; OXIDOREDUCTASE; PEPTIDES AND PROTEINS; POLYKETIDE SYNTHASE; PROTEIN RIFKR7; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; MASS FRAGMENTOGRAPHY; PROTEIN DOMAIN; PROTEIN STRUCTURE; STEREOCHEMISTRY;

BIOCATALYSIS; CARRIER PROTEINS; OXIDATION-REDUCTION; POLYKETIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; STEREOISOMERISM;

EID: 84878258937     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4014776     Document Type: Article

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