Structural and functional analysis of C2-type ketoreductases from modular polyketide synthases

Journal of Molecular Biology

Volumn 410, Issue 1, 2011, Pages 105-117

  Zheng, Jianting ^a   Keatinge Clay, Adrian T ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

ketoreductase; pikromycin; polyketide; polyketide synthase; racemase

Indexed keywords

ALANINE; AMPKR2; ARGININE; ASPARAGINE; CYSTEINE; ERYKR1; ERYKR3; ERYKS4; FATTY ACID SYNTHASE; GENOMIC DNA; GLUTAMINE; KETOREDUCTASE; LYSINE; OXIDOREDUCTASE; PIKKR3; PIKROMYCIN; POLYKETIDE; POLYKETIDE SYNTHASE; PROLINE; PROTON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SERINE; THREONINE; TRYPTOPHAN; TYLKR1; TYROSINE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING SITE; CATALYSIS; CRYSTALLIZATION; CYCLIZATION; DNA BINDING MOTIF; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME SUBSTRATE COMPLEX; EPIMERIZATION; ESTERIFICATION; HYDROGEN BOND; IN VIVO STUDY; MOLECULAR DOCKING; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; RACEMIZATION; STEREOSPECIFICITY; TAUTOMERIZATION;

EID: 79958713315     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.04.065     Document Type: Article

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