메뉴 건너뛰기




Volumn 62, Issue 6, 2013, Pages 1823-1825

Sweet and sour β-cells: ROS and Hif1α induce warburg-like lactate production during type 2 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INSULIN; LACTATE DEHYDROGENASE; LACTIC ACID; REACTIVE OXYGEN METABOLITE;

EID: 84878255497     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0272     Document Type: Note
Times cited : (12)

References (20)
  • 1
    • 33745863033 scopus 로고    scopus 로고
    • Islet β failure in type 2 diabetes
    • Prentki M, Nolan CJ. Islet β failure in type 2 diabetes. J Clin Invest 2006;116:1802-1812
    • (2006) J Clin Invest , vol.116 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 3
    • 12044255619 scopus 로고
    • Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing
    • Sekine N, Cirulli V, Regazzi R, et al. Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing. J Biol Chem 1994;269:4895-4902
    • (1994) J Biol Chem , vol.269 , pp. 4895-4902
    • Sekine, N.1    Cirulli, V.2    Regazzi, R.3
  • 5
    • 43549108142 scopus 로고    scopus 로고
    • Glucolipotoxicity: Fuel excess and β-cell dysfunction
    • DOI 10.1210/er.2007-0023
    • Poitout V, Robertson RP. Glucolipotoxicity: fuel excess and β-cell dysfunction. Endocr Rev 2008;29:351-366 (Pubitemid 351679704)
    • (2008) Endocrine Reviews , vol.29 , Issue.3 , pp. 351-366
    • Poitout, V.1    Robertson, R.P.2
  • 6
    • 84878233692 scopus 로고    scopus 로고
    • Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction
    • Sasaki M, Fujimoto S, Sato Y, et al. Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction. Diabetes 2013;62:1996-2003
    • (2013) Diabetes , vol.62 , pp. 1996-2003
    • Sasaki, M.1    Fujimoto, S.2    Sato, Y.3
  • 7
    • 0033919717 scopus 로고    scopus 로고
    • Acute overexpression of lactate dehydrogenase-A perturbs β-cell mitochondrial metasbolism and insulin secretion
    • Ainscow EK, Zhao C, Rutter GA. Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion. Diabetes 2000;49:1149-1155 (Pubitemid 30439089)
    • (2000) Diabetes , vol.49 , Issue.7 , pp. 1149-1155
    • Ainscow, E.K.1    Zhao, C.2    Rutter, G.A.3
  • 10
    • 24144496798 scopus 로고    scopus 로고
    • Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β-cell differentiation and secretory function in the db/db mouse model of diabetes
    • DOI 10.2337/diabetes.54.9.2755
    • Kjørholt C, Akerfeldt MC, Biden TJ, Laybutt DR. Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. Diabetes 2005;54:2755-2763 (Pubitemid 41233599)
    • (2005) Diabetes , vol.54 , Issue.9 , pp. 2755-2763
    • Kjorholt, C.1    Akerfeldt, M.C.2    Biden, T.J.3    Laybutt, D.R.4
  • 11
    • 31444444162 scopus 로고    scopus 로고
    • Integration of oxygen signaling at the consensus HRE
    • Wenger RH, Stiehl DP, Camenisch G. Integration of oxygen signaling at the consensus HRE. Sci STKE 2005;2005:re12
    • (2005) Sci STKE , vol.2005
    • Wenger, R.H.1    Stiehl, D.P.2    Camenisch, G.3
  • 12
    • 61749090485 scopus 로고    scopus 로고
    • Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice
    • Cantley J, Selman C, Shukla D, et al. Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice. J Clin Invest 2009;119:125-135
    • (2009) J Clin Invest , vol.119 , pp. 125-135
    • Cantley, J.1    Selman, C.2    Shukla, D.3
  • 13
    • 79953167224 scopus 로고    scopus 로고
    • Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice
    • Choi D, Cai EP, Schroer SA, Wang L, Woo M. Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice. Lab Invest 2011;91:527-538
    • (2011) Lab Invest , vol.91 , pp. 527-538
    • Choi, D.1    Cai, E.P.2    Schroer, S.A.3    Wang, L.4    Woo, M.5
  • 14
    • 61949412026 scopus 로고    scopus 로고
    • A role for Von Hippel-Lindau protein in pancreatic β-cell function
    • Puri S, Cano D, Hebrok M. A role for Von Hippel-Lindau protein in pancreatic β-cell function. Diabetes 2008;58:433-441
    • (2008) Diabetes , vol.58 , pp. 433-441
    • Puri, S.1    Cano, D.2    Hebrok, M.3
  • 15
    • 56549094039 scopus 로고    scopus 로고
    • PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells
    • Zehetner J, Danzer C, Collins S, et al. PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells. Genes Dev 2008;22:3135-3146
    • (2008) Genes Dev , vol.22 , pp. 3135-3146
    • Zehetner, J.1    Danzer, C.2    Collins, S.3
  • 17
    • 24144467846 scopus 로고    scopus 로고
    • ROS: Really involved in oxygen sensing
    • Kaelin WG Jr. ROS: really involved in oxygen sensing. Cell Metab 2005;1:357-358
    • (2005) Cell Metab , vol.1 , pp. 357-358
    • Kaelin Jr., W.G.1
  • 18
    • 44749084179 scopus 로고    scopus 로고
    • Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets
    • Kominato R, Fujimoto S, Mukai E, et al. Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets. Diabetologia 2008;51:1226-1235
    • (2008) Diabetologia , vol.51 , pp. 1226-1235
    • Kominato, R.1    Fujimoto, S.2    Mukai, E.3
  • 19
    • 0033553462 scopus 로고    scopus 로고
    • Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes
    • Jonas JC, Sharma A, Hasenkamp W, et al. Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes. J Biol Chem 1999;274:14112-14121
    • (1999) J Biol Chem , vol.274 , pp. 14112-14121
    • Jonas, J.C.1    Sharma, A.2    Hasenkamp, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.