-
1
-
-
73749083481
-
Global estimates of the prevalence of diabetes for 2010 and 2030
-
Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2009;87:4-14.
-
(2009)
Diabetes Res Clin Pract
, vol.87
, pp. 4-14
-
-
Shaw, J.E.1
Sicree, R.A.2
Zimmet, P.Z.3
-
2
-
-
2342466734
-
Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030
-
DOI 10.2337/diacare.27.5.1047
-
Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-1053. (Pubitemid 38579764)
-
(2004)
Diabetes Care
, vol.27
, Issue.5
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
3
-
-
0037283601
-
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
-
Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia 2003;46:3-19. (Pubitemid 36237741)
-
(2003)
Diabetologia
, vol.46
, Issue.1
, pp. 3-19
-
-
Kahn, S.E.1
-
4
-
-
12344323484
-
Type 2 diabetes - A matter of β-cell life and death?
-
DOI 10.1126/science.1104345
-
Rhodes CJ. Type 2 diabetes-a matter of b-cell life and death? Science 2005;307:380-384. (Pubitemid 40139973)
-
(2005)
Science
, vol.307
, Issue.5708
, pp. 380-384
-
-
Rhodes, C.J.1
-
5
-
-
23644433355
-
Mechanisms of compensatory β-cell growth in insulin-resistant rats: Roles of Akt kinase
-
DOI 10.2337/diabetes.54.8.2294
-
Jetton TL, Lausier J, LaRock K, et al. Mechanisms of compensatory betacell growth in insulin resistant rats: roles of Akt kinase. Diabetes 2005;54:2294-2304. (Pubitemid 41134255)
-
(2005)
Diabetes
, vol.54
, Issue.8
, pp. 2294-2304
-
-
Jetton, T.L.1
Lausier, J.2
LaRock, K.3
Trotman, W.E.4
Larmie, B.5
Habibovic, A.6
Peshavaria, M.7
Leahy, J.L.8
-
6
-
-
0037131246
-
β-cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic zucker fatty rats
-
DOI 10.1074/jbc.M207157200
-
Liu YQ, Jetton TL, Leahy JL. Beta-cell adaptation to insulin resistance: increased pyruvate carboxylase activity and anaplerosis in islets of Zucker fatty rats. J Biol Chem 2002;277:39163-39168. (Pubitemid 35190884)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.42
, pp. 39163-39168
-
-
Liu, Y.Q.1
Jetton, T.L.2
Leahy, J.L.3
-
7
-
-
0035008598
-
Adaptation of beta-cell mass to substrate oversupply: Enhanced function with normal gene expression
-
Steil GM, Trivedi N, Jonas JC, et al. Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression. Am J Physiol Endocrinol Metab 2001;280:E788-E796.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
-
-
Steil, G.M.1
Trivedi, N.2
Jonas, J.C.3
-
8
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
DOI 10.2337/diabetes.52.1.102
-
Butler AE, Janson J, Bonner-Weir S, et al. Beta-cell deficit and increased apoptosis in humans with type-2 diabetes. Diabetes 2003;52: 102-110. (Pubitemid 36042113)
-
(2003)
Diabetes
, vol.52
, Issue.1
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
9
-
-
0031972156
-
UKPDS 26: Sulphonylurea failure in non-insulin-dependent diabetic patients over six years
-
DOI 10.1002/(SICI)1096-9136(19 9804)15:4<297::AID-DIA572>3.0.CO;2-W
-
Matthews DR, Cull CA, Stratton IM, et al. UKPDS 26: Sulphonylurea failure in non-insulin-dependent diabetic patients over six years. UK Prospective Diabetes Study (UKPDS) Group. Diabetic Med 1998;15:297-303. (Pubitemid 28168509)
-
(1998)
Diabetic Medicine
, vol.15
, Issue.4
, pp. 297-303
-
-
Matthews, D.R.1
Cull, C.A.2
Stratton, I.M.3
Holman, R.R.4
Turner, R.C.5
-
10
-
-
0036153256
-
Minireview: Secondary β-cell failure in type 2 diabetes - A convergence of glucotoxicity and lipotoxicity
-
DOI 10.1210/en.143.2.339
-
Poitout V, Roberston RP. Secondary beta-cell failure in type 2 diabetes. A convergence of glucotoxicity and lipotoxicity. Endocrinology 2002;143:339-342. (Pubitemid 34107184)
-
(2002)
Endocrinology
, vol.143
, Issue.2
, pp. 339-342
-
-
Poitout, V.1
Robertson, R.P.2
-
11
-
-
33745863033
-
Islet β cell failure in type 2 diabetes
-
DOI 10.1172/JCI29103
-
Prentki M, Nolan CJ. Islet b-cell failure in type 2 diabetes. J Clin Invest 2006;116:1802-1812. (Pubitemid 44033300)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1802-1812
-
-
Prentki, M.1
Nolan, C.J.2
-
12
-
-
23744439083
-
Loss of ARNT/HIF1β mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes
-
DOI 10.1016/j.cell.2005.05.027, PII S0092867405005416
-
Gunton JE, Kulkarni RN, Yim S, et al. Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes. Cell 2005;122:337-349. (Pubitemid 41127137)
-
(2005)
Cell
, vol.122
, Issue.3
, pp. 337-349
-
-
Gunton, J.E.1
Kulkarni, R.N.2
Yim, S.3
Okada, T.4
Hawthorne, W.J.5
Tseng, Y.-H.6
Roberson, R.S.7
Ricordi, C.8
O'Connell, P.J.9
Gonzalez, F.J.10
Kahn, C.R.11
-
13
-
-
0029842459
-
Oxygen sensing and molecular adaptation to hypoxia
-
Bunn HF, Poyton RO. Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 1996;76:839-885. (Pubitemid 26286080)
-
(1996)
Physiological Reviews
, vol.76
, Issue.3
, pp. 839-885
-
-
Bunn, H.F.1
Poyton, R.O.2
-
14
-
-
0031304718
-
Hypoxia response elements
-
O'Rourke JF, Dachs GU, Gleadle JM, et al. Hypoxia response elements. Oncol Res 1997;9:327-332. (Pubitemid 127825986)
-
(1997)
Oncology Research
, vol.9
, Issue.6-7
, pp. 327-332
-
-
O'Rourke, J.F.1
Dachs, G.U.2
Gleadle, J.M.3
Maxwell, P.H.4
Pugh, C.W.5
Stratford, I.J.6
-
15
-
-
0034663989
-
Hif-1 and human disease: One highly involved factor
-
Semenza GL. HIF-1 and human disease: one highly involved factor. Genes Dev 2000;14:1983-1991. (Pubitemid 30637348)
-
(2000)
Genes and Development
, vol.14
, Issue.16
, pp. 1983-1991
-
-
Semenza, G.L.1
-
16
-
-
1842416574
-
Oxygen(es) and the hypoxia-inducible factor-1
-
Wenger RH, Gassman M. Oxygen(es) and the hypoxia-inducible factor-1. Biol Chem 1997;378:609-616. (Pubitemid 27361853)
-
(1997)
Biological Chemistry
, vol.378
, Issue.7
, pp. 609-616
-
-
Wenger, R.H.1
Gassmann, M.2
-
18
-
-
33745763116
-
Cerebral preconditioning and ischaemic tolerance
-
DOI 10.1038/nrn1927, PII NRN1927
-
Gidday JM. Cerebral preconditioning and ischaemic tolerance. Nat Rev Neurosci 2006;7:437-448. (Pubitemid 44012284)
-
(2006)
Nature Reviews Neuroscience
, vol.7
, Issue.6
, pp. 437-448
-
-
Gidday, J.M.1
-
19
-
-
27844440474
-
Realizing the clinical potential of ischemic preconditioning and postconditioning
-
DOI 10.1038/ncpcardio0346, PII N0346
-
Yellon DM, Hausenloy DJ. Realizing the clinical potential of ischemic preconditioning and postconditioning. Nat Clin Pract Cardiovasc Med 2005;2:568-575. (Pubitemid 41655660)
-
(2005)
Nature Clinical Practice Cardiovascular Medicine
, vol.2
, Issue.11
, pp. 568-575
-
-
Yellon, D.M.1
Hausenloy, D.J.2
-
20
-
-
0032898369
-
Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic β cell-specific gene knock-outs using Cre recombinase
-
DOI 10.1074/jbc.274.1.305
-
Postic C, Shiota M, Niswender KD, et al. Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cellspecific gene knock-outs using cre recombinase. J Biol Chem 1999;274:305-315. (Pubitemid 29035064)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.1
, pp. 305-315
-
-
Postic, C.1
Shiota, M.2
Niswender, K.D.3
Jetton, T.L.4
Chen, Y.5
Moates, J.M.6
Shelton, K.D.7
Lindner, J.8
Cherrington, A.D.9
Magnuson, M.A.10
-
21
-
-
0030847165
-
Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice
-
Gnarra JR, Ward JM, Porter FD, et al. Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice. Proc Natl Acad Sci USA 2005;94:9102-9107.
-
(2005)
Proc Natl Acad Sci USA
, vol.94
, pp. 9102-9107
-
-
Gnarra, J.R.1
Ward, J.M.2
Porter, F.D.3
-
22
-
-
17644379373
-
Caspase-3-dependent β-cell apoptosis in the initiation of autoimmune diabetes mellitus
-
DOI 10.1128/MCB.25.9.3620-3629.2005
-
Liadis N, Murakami K, Eweida M, et al. Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus. Mol Cell Biol 2005;25:3620-3629. (Pubitemid 40559568)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.9
, pp. 3620-3629
-
-
Liadis, N.1
Murakami, K.2
Eweida, M.3
Elford, A.R.4
Sheu, L.5
Gaisano, H.Y.6
Hakem, R.7
Ohashi, P.S.8
Woo, M.9
-
23
-
-
19944430614
-
Muscle-specific Pten deletion protects against insulin resistance and diabetes
-
DOI 10.1128/MCB.25.3.1135-1145.2005
-
Wijesekara N, Konrad D, Eweida M, et al. Muscle-specific PTEN deletion protects against insulin resistance and diabetes. Mol Cell Biol 2005;25:1135-1145. (Pubitemid 40165819)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.3
, pp. 1135-1145
-
-
Wijesekara, N.1
Konrad, D.2
Eweida, M.3
Jefferies, C.4
Liadis, N.5
Giacca, A.6
Crackower, M.7
Suzuki, A.8
Mak, T.W.9
Kahn, C.R.10
Klip, A.11
Woo, M.12
-
24
-
-
33244474401
-
Delayed administration of erythropoietin and its non-erythropoietic derivatives ameliorates chronic murine autoimmune encephalomyelitis
-
DOI 10.1016/j.jneuroim.2005.10.016, PII S0165572805004601
-
Savino C, Pedotti R, Baggi F, et al. Delayed administration of erythropoietin and its non-erythropoietic derivatives ameliorates chronic autoimmune encephalomyelitis. J Neuroimmunol 2006;172:27-37. (Pubitemid 43279681)
-
(2006)
Journal of Neuroimmunology
, vol.172
, Issue.1-2
, pp. 27-37
-
-
Savino, C.1
Pedotti, R.2
Baggi, F.3
Ubiali, F.4
Gallo, B.5
Nava, S.6
Bigini, P.7
Barbera, S.8
Fumagalli, E.9
Mennini, T.10
Vezzani, A.11
Rizzi, M.12
Coleman, T.13
Cerami, A.14
Brines, M.15
Ghezzi, P.16
Bianchi, R.17
-
25
-
-
20144389727
-
The role of insulin receptor substrate 2 in hypothalamic and β cell function
-
DOI 10.1172/JCI200524445
-
Choudhury AI, Heffron H, Smith MA, et al. The role of the insulin receptor substrate 2 in hypothalamic and beta cell function. J Clin Invest 2005;115:940-950. (Pubitemid 40489398)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.4
, pp. 940-950
-
-
Choudhury, A.I.1
Heffron, H.2
Smith, M.A.3
Al-Qassab, H.4
Xu, A.W.5
Selman, C.6
Simmgen, M.7
Clements, M.8
Claret, M.9
MacColl, G.10
Bedford, D.C.11
Hisadome, K.12
Diakonov, I.13
Moosajee, V.14
Bell, J.D.15
Speakman, J.R.16
Batterham, R.L.17
Barsh, G.S.18
Ashford, M.L.J.19
Withers, D.J.20
more..
-
26
-
-
33745030531
-
Essential role of Pten in body size determination and pancreatic β-cell homeostasis in vivo
-
DOI 10.1128/MCB.00238-06
-
Nguyen KT, Tajmir P, Lin CH, et al. Essential role of Pten in body size determination and pancreatic b-cell homeostasis in vivo. Mol Cell Biol 2006;26:4511-4518. (Pubitemid 43877571)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.12
, pp. 4511-4518
-
-
Nguyen, K.-T.T.1
Tajmir, P.2
Lin, C.H.3
Liadis, N.4
Zhu, X.-D.5
Eweida, M.6
Tolasa-Karaman, G.7
Cai, F.8
Wang, R.9
Kitamura, T.10
Belsham, D.D.11
Wheeler, M.B.12
Suzuki, A.13
Mak, T.W.14
Woo, M.15
-
27
-
-
61749090485
-
Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice
-
Cantley J, Selman C, Shukla D, et al. Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice. J Clin Invest 2009;119:125-135.
-
(2009)
J Clin Invest
, vol.119
, pp. 125-135
-
-
Cantley, J.1
Selman, C.2
Shukla, D.3
-
28
-
-
4644310308
-
Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells
-
DOI 10.1182/blood-2004-02-0744
-
Beleslin-Cokic BB, Cokic VP, Yu X, et al. Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells. Blood 2004;104:2073-2080. (Pubitemid 39297859)
-
(2004)
Blood
, vol.104
, Issue.7
, pp. 2073-2080
-
-
Beleslin-Cokic, B.B.1
Cokic, V.P.2
Yu, X.3
Weksler, B.B.4
Schechter, A.N.5
Noguchi, C.T.6
-
29
-
-
34347227058
-
Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
-
DOI 10.1042/BJ20070389
-
Semenza GL. Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. Biochem J 2007;405:1-9. (Pubitemid 46999919)
-
(2007)
Biochemical Journal
, vol.405
, Issue.1
, pp. 1-9
-
-
Semenza, G.L.1
-
30
-
-
0018639093
-
Endocrine pancreas: Three-dimensional reconstruction shows two types of islets of Langerhans
-
Beatens D, Malaisse-Lagae F, Perrelet A, et al. Endocrine pancreas: three-dimensional reconstruction shows two types of islets of Langerhans. Science 1979;206:1323-1325. (Pubitemid 10170025)
-
(1979)
Science
, vol.206
, Issue.4424
, pp. 1323-1325
-
-
Baetens, D.1
Malaisse-Lagae, F.2
Perrelet, A.3
Orci, L.4
-
31
-
-
0036320934
-
2- regulated gene expression
-
DOI 10.1096/fj.01-0944rev
-
Wenger RH. Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2- regulated gene expression. FASEB J 2002;16:1151-1162. (Pubitemid 34815403)
-
(2002)
FASEB Journal
, vol.16
, Issue.10
, pp. 1151-1162
-
-
Wenger, R.H.1
-
32
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: Role of the HIF system
-
DOI 10.1038/nm0603-677
-
Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 2003;9:677-684. (Pubitemid 36749216)
-
(2003)
Nature Medicine
, vol.9
, Issue.6
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
33
-
-
0023837516
-
Peritubular cells are the site of erythropoietin synthesis in the murine hypoxic kidney
-
Lacombe C, Da Silva JL, Bruneval P, et al. Peritubular cells are the site of erythropoietin synthesis in the murine hypoxic kidney. J Clin Invest 1998;81:620-623.
-
(1998)
J Clin Invest
, vol.81
, pp. 620-623
-
-
Lacombe, C.1
Da Silva, J.L.2
Bruneval, P.3
-
36
-
-
0025732160
-
Erythropoietin is both a mitogen and a survival factor
-
Spivak JL, Pham T, Isaacs M, et al. Erythropoietin is both a mitogen and a survival factor. Blood 1991;77:1228-1233.
-
(1991)
Blood
, vol.77
, pp. 1228-1233
-
-
Spivak, J.L.1
Pham, T.2
Isaacs, M.3
-
37
-
-
0037469029
-
Human, nonhuman primate, and rat pancreatic islets express erythropoietin receptors
-
DOI 10.1097/01.TP.0000062862.88375.BD
-
Fenjves ES, Ochoa MS, Cabrera O, et al. Human, nonhuman primate, and rat pancreatic islets express erythropoietin receptors. Transplantation 2003;75:1356-1360. (Pubitemid 36513048)
-
(2003)
Transplantation
, vol.75
, Issue.8
, pp. 1356-1360
-
-
Fenjves, E.S.1
Ochoa, M.S.2
Cabrera, O.3
Mendez, A.J.4
Kenyon, N.S.5
Inverardi, L.6
Ricordi, C.7
-
38
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
DOI 10.1038/20459
-
Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999;399:271-275. (Pubitemid 29246458)
-
(1999)
Nature
, vol.399
, Issue.6733
, pp. 271-275
-
-
Maxwell, P.H.1
Wlesener, M.S.2
Chang, G.-W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
39
-
-
0037709883
-
Von Hippel-Lindau disease
-
DOI 10.1016/S0140-6736(03)13643-4
-
Lonser RR, Glen GM, Walther M, et al. Von Hippel-Lindau disease. Lancet 2003;361:2059-2067. (Pubitemid 36695052)
-
(2003)
Lancet
, vol.361
, Issue.9374
, pp. 2059-2067
-
-
Lonser, R.R.1
Glenn, G.M.2
Walther, M.3
Chew, E.Y.4
Libutti, S.K.5
Linehan, W.M.6
Oldfield, E.H.7
-
40
-
-
64549146243
-
Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations
-
Shen HC, Adem A, Ylaya K, et al. Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations. PLoS One 2009;4:e4897.
-
(2009)
PLoS One
, vol.4
-
-
Shen, H.C.1
Adem, A.2
Ylaya, K.3
-
41
-
-
61949412026
-
A role for von Hippel-Lindau protein in pancreatic beta-cell function
-
Puri S, Cano DA, Hebrok M. A role for von Hippel-Lindau protein in pancreatic beta-cell function. Diabetes 2009;58:433-441.
-
(2009)
Diabetes
, vol.58
, pp. 433-441
-
-
Puri, S.1
Cano, D.A.2
Hebrok, M.3
-
42
-
-
56549094039
-
PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells
-
Zehetner J, Danzer C, Collins S, et al. PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells. Genes Dev 2008;22:3135-3146.
-
(2008)
Genes Dev
, vol.22
, pp. 3135-3146
-
-
Zehetner, J.1
Danzer, C.2
Collins, S.3
-
43
-
-
0032694633
-
CPP32/CASPASE-3-like proteases in hypoxia-induced apoptosis in developing brain neurons
-
DOI 10.1016/S0169-328X(99)00190-4, PII S0169328X99001904
-
Bossenmeyer-Pourle C, Koziel V, Daval JL. CPP32/Caspase-3-like proteases in hypoxia-induced apoptosis in developing brain neurons. Mol Brain Res 1999;71:225-237. (Pubitemid 29492967)
-
(1999)
Molecular Brain Research
, vol.71
, Issue.2
, pp. 225-237
-
-
Bossenmeyer-Pourie, C.1
Koziel, V.2
Daval, J.-L.3
-
44
-
-
0036352616
-
Hypoxia-induced cleavage of caspase-3 and DFF45/ICAD in human failed cardiomyocytes
-
Todor A, Sharov VG, Tanhehco EJ, et al. Hypoxia-induced cleavage of caspase-3 and DFF45/ICAD in human failed cardiomyocytes. Am J Physiol Heart Circ Physiol 2002;283:H990-H995.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Todor, A.1
Sharov, V.G.2
Tanhehco, E.J.3
-
45
-
-
77954813138
-
New insights into endocrine pancreatic development: The role of environmental factors
-
Heinis M, Simon MT, Duvillié B. New insights into endocrine pancreatic development: the role of environmental factors. Horm Res Paediatr 2010;74:77-82.
-
(2010)
Horm Res Paediatr
, vol.74
, pp. 77-82
-
-
Heinis, M.1
Simon, M.T.2
Duvillié, B.3
-
46
-
-
77950344913
-
Oxygen tension regulates pancreatic b-cell differentiation through HIF1
-
Heinis M, Simon MT, Ilc K, et al. Oxygen tension regulates pancreatic b-cell differentiation through HIF1. Diabetes 2010;59: 662-669.
-
(2010)
Diabetes
, vol.59
, pp. 662-669
-
-
Heinis, M.1
Simon, M.T.2
Ilc, K.3
-
47
-
-
0034652287
-
Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
DOI 10.1073/pnas.97.4.1607
-
Gradwohl G, Dierich A, LeMeur M, et al. Neurogenin-3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci USA 2000;97:1607-1611. (Pubitemid 30118489)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.4
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
Guillemot, F.4
-
48
-
-
0031449202
-
The loss of GLUT2 expression in the pancreatic β-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors
-
DOI 10.1016/S0303-7207(97)00190-1, PII S0303720797001901
-
Bonny C, Roduit R, Gremlich S, et al. The loss of GLUT2 expression in the pancreatic beta-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific transacting factors. Mol Cell Endocrinol 1997;135:59-65. (Pubitemid 28010414)
-
(1997)
Molecular and Cellular Endocrinology
, vol.135
, Issue.1
, pp. 59-65
-
-
Bonny, C.1
Roduit, R.2
Gremlich, S.3
Nicod, P.4
Thorens, B.5
Waeber, G.6
-
49
-
-
0027193976
-
GLUT2 expression and function in β-cells of GK rats with NIDDM: Dissociation between reductions in glucose transport and glucose-stimulated insulin secretion
-
Ohneda M, Johnson JH, Inman LR, et al. GLUT2 expression and function in beta-cells of GK rats with NIDDM: dissociation between reductions in glucose transport and glucose-stimulated insulin secretion. Diabetes 1993;42:1065-1072. (Pubitemid 23182173)
-
(1993)
Diabetes
, vol.42
, Issue.7
, pp. 1065-1072
-
-
Ohneda, M.1
Johnson, J.H.2
Inman, L.R.3
Chen, L.4
Suzuki, K.-I.5
Goto, Y.6
Alam, T.7
Ravazzola, M.8
Orci, L.9
Unger, R.H.10
-
50
-
-
33845582804
-
Islet microvasculature in islet hyperplasia and failure in a model of type 2 diabetes
-
DOI 10.2337/db06-0733
-
Li X, Zhang L, Meshinchi S, et al. Islet microvasculature in islet hyperplasia and failure in a model of type 2 diabetes. Diabetes 2006;55:2965-2973. (Pubitemid 44929429)
-
(2006)
Diabetes
, vol.55
, Issue.11
, pp. 2965-2973
-
-
Li, X.1
Zhang, L.2
Meshinchi, S.3
Dias-Leme, C.4
Raffin, D.5
Johnson, J.D.6
Treutelaar, M.K.7
Burant, C.F.8
-
51
-
-
0027470723
-
Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans
-
Dionne KE, Colton CK, Yarmush ML. Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans. Diabetes 1993;42:12-21. (Pubitemid 23013790)
-
(1993)
Diabetes
, vol.42
, Issue.1
, pp. 12-21
-
-
Dionne, K.E.1
Colton, C.K.2
Yarmush, M.L.3
-
52
-
-
0020183956
-
The effect of hypoxia on insulin and glucagon secretion in the perfused pancreas of the rat
-
Narimiya M, Yamada H, Matsuba I, et al. The effect of hypoxia on insulin and glucagon secretion in the perfused pancreas of the rat. Endocrinology 1982;111:1010-1014.
-
(1982)
Endocrinology
, vol.111
, pp. 1010-1014
-
-
Narimiya, M.1
Yamada, H.2
Matsuba, I.3
-
53
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
DOI 10.1038/414799a
-
Saltiel AR, Kahn CR. Insulin signaling and the regulation of glucose and lipid metabolism. Nature 2001;414:799-806. (Pubitemid 34000783)
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
54
-
-
1642484480
-
Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets
-
DOI 10.1097/01.TP.0000110422.27977.26
-
Fenjves ES, Ochoa MS, Gay-Ravinstein C, et al. Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets. Transplantation 2004;77:13-18. (Pubitemid 38116865)
-
(2004)
Transplantation
, vol.77
, Issue.1
, pp. 13-18
-
-
Fenjves, E.S.1
Ochoa, M.S.2
Gay-Rabinstein, C.3
Molano, R.D.4
Pileggi, A.5
Mendez, A.J.6
Inverardi, L.7
Ricordi, C.8
-
55
-
-
0037119415
-
Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1a-degradative pathway
-
Isaacs JS, Jung YJ, Mimnaugh EG, et al. Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1a-degradative pathway. J Biol chem 2002;277:29936-29944.
-
(2002)
J Biol Chem
, vol.277
, pp. 29936-29944
-
-
Isaacs, J.S.1
Jung, Y.J.2
Mimnaugh, E.G.3
-
56
-
-
33846254999
-
2-Independent and HSP90 Inhibitor-Induced Degradation of HIF-1α
-
DOI 10.1016/j.molcel.2007.01.001, PII S1097276507000020
-
Liu YV, Baek JH, Zhang H, et al. RACK1 Competes with HSP90 for binding to HIF-1a and is required for O2-independent and HSP90 inhibitor-induced degradation of HIF-1a. Mol Cell 2007;25:207-217. (Pubitemid 46109612)
-
(2007)
Molecular Cell
, vol.25
, Issue.2
, pp. 207-217
-
-
Liu, Y.V.1
Baek, J.H.2
Zhang, H.3
Diez, R.4
Cole, R.N.5
Semenza, G.L.6
-
57
-
-
34247583794
-
Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1α and mediates its destabilization in a VHL-independent manner
-
DOI 10.1128/MCB.00015-07
-
Flü gel D, Gö rlach A, Michiels C, et alGlycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1 and mediates its destabilization in a VHL-independent manner. Mol Cell Biol 2007, 27: 3253-3265. (Pubitemid 46685205)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.9
, pp. 3253-3265
-
-
Flugel, D.1
Gorlach, A.2
Michiels, C.3
Kietzmann, T.4
-
58
-
-
33644780111
-
Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1α
-
DOI 10.1128/MCB.26.6.2019-2028.2006
-
Kong X, Lin Z, Liang D, et al. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxiainducible factor 1a. Mol Cell Biol 2006;26:2019-2028. (Pubitemid 43346906)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.6
, pp. 2019-2028
-
-
Kong, X.1
Lin, Z.2
Liang, D.3
Fath, D.4
Sang, N.5
Caro, J.6
-
59
-
-
57049135307
-
Ser9-phosphorylation of mitochondrial GSK-3{beta} is a primary mechanism of cardiomyocyte protection by erythropoietin against oxidant-induced apoptosis
-
Ohori K, Miura T, Tanno M, et al. Ser9-phosphorylation of mitochondrial GSK-3{beta} is a primary mechanism of cardiomyocyte protection by erythropoietin against oxidant-induced apoptosis. Am J Physiol Heart Circ Physiol 2008;295:2079-2086.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
, pp. 2079-2086
-
-
Ohori, K.1
Miura, T.2
Tanno, M.3
-
60
-
-
18744378310
-
Recombinant human erythropoietin pretreatment attenuates myocardial infarct size: A possible mechanism involves heat shock protein 70 and attenuation of nuclear factor-kappaB
-
Xu B, Dong GH, Liu H, et al. human erythropoietin pretreatment attenuates myocardial infarct size: a possible mechanism involves heat shock protein 70 and attenuation of nuclear factor-kappaB. Ann Clin Lab Sci 2005;35:161-168. (Pubitemid 40677109)
-
(2005)
Annals of Clinical and Laboratory Science
, vol.35
, Issue.2
, pp. 161-168
-
-
Xu, B.1
Dong, G.-H.2
Liu, H.3
Wang, Y.-Q.4
Wu, H.-W.5
Jing, H.6
-
61
-
-
0030707689
-
Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2
-
DOI 10.1038/ng1197-327
-
Guillam MT, Hümmler E, Schaerer E, et al. Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2. Nat Genet 1997;17:327-330. (Pubitemid 27475998)
-
(1997)
Nature Genetics
, vol.17
, Issue.3
, pp. 327-330
-
-
Guillam, M.-T.1
Hummler, E.2
Schaerer, E.3
Wu, J.-Y.4
Birnbaum, M.J.5
Beermann, F.6
Schmidt, A.7
Deriaz, N.8
Thorens, B.9
|