-
1
-
-
7944233158
-
Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases
-
D.J. Selkoe Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases Nat Cell Biol 6 2004 1054 1061
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1054-1061
-
-
Selkoe, D.J.1
-
2
-
-
33846435323
-
Abeta40 inhibits amyloid deposition in vivo
-
J. Kim, L. Onstead, S. Randle, R. Price, L. Smithson, C. Zwizinski, D.W. Dickson, T. Golde, and E. McGowan Abeta40 inhibits amyloid deposition in vivo J Neurosci 27 2007 627 633
-
(2007)
J Neurosci
, vol.27
, pp. 627-633
-
-
Kim, J.1
Onstead, L.2
Randle, S.3
Price, R.4
Smithson, L.5
Zwizinski, C.6
Dickson, D.W.7
Golde, T.8
McGowan, E.9
-
3
-
-
80052501210
-
Resolving controversies on the path to Alzheimer's therapeutics
-
[Erratum appeared in Nat Med 2011, 17:1521 and in Nat Med 2011, 17:1693]
-
D.J. Selkoe Resolving controversies on the path to Alzheimer's therapeutics [Erratum appeared in Nat Med 2011, 17:1521 and in Nat Med 2011, 17:1693] Nat Med 17 2011 1060 1065
-
(2011)
Nat Med
, vol.17
, pp. 1060-1065
-
-
Selkoe, D.J.1
-
4
-
-
35348860241
-
Presenilin: Running with scissors in the membrane
-
D.J. Selkoe, and M.S. Wolfe Presenilin: running with scissors in the membrane Cell 131 2007 215 221
-
(2007)
Cell
, vol.131
, pp. 215-221
-
-
Selkoe, D.J.1
Wolfe, M.S.2
-
5
-
-
67649488309
-
Abeta43 is more frequent than Abeta40 in amyloid plaque cores from Alzheimer disease brains
-
H. Welander, J. Frånberg, C. Graff, E. Sundström, B. Winblad, and L.O. Tjernberg Abeta43 is more frequent than Abeta40 in amyloid plaque cores from Alzheimer disease brains J Neurochem 110 2009 697 706
-
(2009)
J Neurochem
, vol.110
, pp. 697-706
-
-
Welander, H.1
Frånberg, J.2
Graff, C.3
Sundström, E.4
Winblad, B.5
Tjernberg, L.O.6
-
6
-
-
0037384938
-
Characteristic developmental expression of amyloid beta40, 42 and 43 in patients with Down syndrome
-
A. Hirayama, Y. Horikoshi, M. Maeda, M. Ito, and S. Takashima Characteristic developmental expression of amyloid beta40, 42 and 43 in patients with Down syndrome Brain Dev 25 2003 180 185
-
(2003)
Brain Dev
, vol.25
, pp. 180-185
-
-
Hirayama, A.1
Horikoshi, Y.2
Maeda, M.3
Ito, M.4
Takashima, S.5
-
7
-
-
79960819248
-
Potent amyloidogenicity and pathogenicity of Abeta43
-
T. Saito, T. Suemoto, N. Brouwers, K. Sleegers, S. Funamoto, N. Mihira, Y. Matsuba, K. Yamada, P. Nilsson, J. Takano, M. Nishimura, N. Iwata, C. Van Broeckhoven, Y. Ihara, and T.C. Saido Potent amyloidogenicity and pathogenicity of Abeta43 Nat Neurosci 14 2011 1023 1032
-
(2011)
Nat Neurosci
, vol.14
, pp. 1023-1032
-
-
Saito, T.1
Suemoto, T.2
Brouwers, N.3
Sleegers, K.4
Funamoto, S.5
Mihira, N.6
Matsuba, Y.7
Yamada, K.8
Nilsson, P.9
Takano, J.10
Nishimura, M.11
Iwata, N.12
Van Broeckhoven, C.13
Ihara, Y.14
Saido, T.C.15
-
8
-
-
34547871652
-
Angiotensin-converting enzyme converts amyloid beta-protein 1-42 (Abeta(1-42)) to Abeta(1-40), and its inhibition enhances brain Abeta deposition
-
K. Zou, H. Yamaguchi, H. Akatsu, T. Sakamoto, M. Ko, K. Mizoguchi, J.S. Gong, W. Yu, T. Yamamoto, K. Kosaka, K. Yanagisawa, and M. Michikawa Angiotensin-converting enzyme converts amyloid beta-protein 1-42 (Abeta(1-42)) to Abeta(1-40), and its inhibition enhances brain Abeta deposition J Neurosci 27 2007 8628 8635
-
(2007)
J Neurosci
, vol.27
, pp. 8628-8635
-
-
Zou, K.1
Yamaguchi, H.2
Akatsu, H.3
Sakamoto, T.4
Ko, M.5
Mizoguchi, K.6
Gong, J.S.7
Yu, W.8
Yamamoto, T.9
Kosaka, K.10
Yanagisawa, K.11
Michikawa, M.12
-
9
-
-
1042265065
-
Alzheimer disease risk and genetic variation in ACE: A meta-analysis
-
J.S. Elkins, V.C. Douglas, and S.C. Johnston Alzheimer disease risk and genetic variation in ACE: a meta-analysis Neurology 62 2004 363 368
-
(2004)
Neurology
, vol.62
, pp. 363-368
-
-
Elkins, J.S.1
Douglas, V.C.2
Johnston, S.C.3
-
10
-
-
23944438473
-
Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease
-
D.J. Lehmann, M. Cortina-Borja, D.R. Warden, A.D. Smith, K. Sleegers, J.A. Prince, C.M. van Duijn, and P.G. Kehoe Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease Am J Epidemiol 162 2005 305 317
-
(2005)
Am J Epidemiol
, vol.162
, pp. 305-317
-
-
Lehmann, D.J.1
Cortina-Borja, M.2
Warden, D.R.3
Smith, A.D.4
Sleegers, K.5
Prince, J.A.6
Van Duijn, C.M.7
Kehoe, P.G.8
-
11
-
-
70450257558
-
Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme
-
K. Zou, T. Maeda, A. Watanabe, J. Liu, S. Liu, R. Oba, Y. Satoh, H. Komano, and M. Michikawa Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme J Biol Chem 284 2009 31914 31920
-
(2009)
J Biol Chem
, vol.284
, pp. 31914-31920
-
-
Zou, K.1
Maeda, T.2
Watanabe, A.3
Liu, J.4
Liu, S.5
Oba, R.6
Satoh, Y.7
Komano, H.8
Michikawa, M.9
-
12
-
-
77958507752
-
The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: Clinical report and quantification of Abeta in different brain regions
-
L. Keller, H. Welander, H.H. Chiang, L.O. Tjernberg, I. Nennesmo, A.K. Wallin, and C. Graff The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: clinical report and quantification of Abeta in different brain regions Eur J Hum Genet 18 2010 1202 1208
-
(2010)
Eur J Hum Genet
, vol.18
, pp. 1202-1208
-
-
Keller, L.1
Welander, H.2
Chiang, H.H.3
Tjernberg, L.O.4
Nennesmo, I.5
Wallin, A.K.6
Graff, C.7
-
13
-
-
0034213718
-
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
-
L. Mucke, E. Masliah, G.Q. Yu, M. Mallory, E.M. Rockenstein, G. Tatsuno, K. Hu, D. Kholodenko, K. Johnson-Wood, and L. McConlogue High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation J Neurosci 20 2000 4050 4058
-
(2000)
J Neurosci
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.Q.3
Mallory, M.4
Rockenstein, E.M.5
Tatsuno, G.6
Hu, K.7
Kholodenko, D.8
Johnson-Wood, K.9
McConlogue, L.10
-
14
-
-
0025600931
-
Diffuse plaques do not accentuate synapse loss in Alzheimer's disease
-
E. Masliah, R.D. Terry, M. Mallory, M. Alford, and L.A. Hansen Diffuse plaques do not accentuate synapse loss in Alzheimer's disease Am J Pathol 137 1990 1293 1297
-
(1990)
Am J Pathol
, vol.137
, pp. 1293-1297
-
-
Masliah, E.1
Terry, R.D.2
Mallory, M.3
Alford, M.4
Hansen, L.A.5
-
15
-
-
0034744296
-
TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice
-
T. Wyss-Coray, C. Lin, F. Yan, G.Q. Yu, M. Rohde, L. McConlogue, E. Masliah, and L. Mucke TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice Nat Med 7 2001 612 618
-
(2001)
Nat Med
, vol.7
, pp. 612-618
-
-
Wyss-Coray, T.1
Lin, C.2
Yan, F.3
Yu, G.Q.4
Rohde, M.5
McConlogue, L.6
Masliah, E.7
Mucke, L.8
-
16
-
-
22544482926
-
Abeta42 is essential for parenchymal and vascular amyloid deposition in mice
-
E. McGowan, F. Pickford, J. Kim, L. Onstead, J. Eriksen, C. Yu, L. Skipper, M.P. Murphy, J. Beard, P. Das, K. Jansen, M. Delucia, W.L. Lin, G. Dolios, R. Wang, C.B. Eckman, D.W. Dickson, M. Hutton, J. Hardy, and T. Golde Abeta42 is essential for parenchymal and vascular amyloid deposition in mice Neuron 47 2005 191 199
-
(2005)
Neuron
, vol.47
, pp. 191-199
-
-
McGowan, E.1
Pickford, F.2
Kim, J.3
Onstead, L.4
Eriksen, J.5
Yu, C.6
Skipper, L.7
Murphy, M.P.8
Beard, J.9
Das, P.10
Jansen, K.11
Delucia, M.12
Lin, W.L.13
Dolios, G.14
Wang, R.15
Eckman, C.B.16
Dickson, D.W.17
Hutton, M.18
Hardy, J.19
Golde, T.20
more..
-
17
-
-
78751519245
-
Association of plasma beta-amyloid level and cognitive reserve with subsequent cognitive decline
-
K. Yaffe, A. Weston, N.R. Graff-Radford, S. Satterfield, E.M. Simonsick, S.G. Younkin, L.H. Younkin, L. Kuller, H.N. Ayonayon, J. Ding, and T.B. Harris Association of plasma beta-amyloid level and cognitive reserve with subsequent cognitive decline JAMA 305 2011 261 266
-
(2011)
JAMA
, vol.305
, pp. 261-266
-
-
Yaffe, K.1
Weston, A.2
Graff-Radford, N.R.3
Satterfield, S.4
Simonsick, E.M.5
Younkin, S.G.6
Younkin, L.H.7
Kuller, L.8
Ayonayon, H.N.9
Ding, J.10
Harris, T.B.11
-
18
-
-
0141738373
-
CSF markers for incipient Alzheimer's disease
-
K. Blennow, and H. Hampel CSF markers for incipient Alzheimer's disease Lancet Neurol 2 2003 605 613
-
(2003)
Lancet Neurol
, vol.2
, pp. 605-613
-
-
Blennow, K.1
Hampel, H.2
-
19
-
-
78650513585
-
Higher activity of peripheral blood angiotensin-converting enzyme is associated with later-onset of Alzheimer's disease
-
H. Akatsu, N. Ogawa, T. Kanesaka, A. Hori, T. Yamamoto, N. Matsukawa, and M. Michikawa Higher activity of peripheral blood angiotensin-converting enzyme is associated with later-onset of Alzheimer's disease J Neurol Sci 300 2011 67 73
-
(2011)
J Neurol Sci
, vol.300
, pp. 67-73
-
-
Akatsu, H.1
Ogawa, N.2
Kanesaka, T.3
Hori, A.4
Yamamoto, T.5
Matsukawa, N.6
Michikawa, M.7
-
20
-
-
0028885854
-
GM1 ganglioside-bound amyloid beta-protein (A beta): A possible form of preamyloid in Alzheimer's disease
-
K. Yanagisawa, A. Odaka, N. Suzuki, and Y. Ihara GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease Nat Med 1 1995 1062 1066
-
(1995)
Nat Med
, vol.1
, pp. 1062-1066
-
-
Yanagisawa, K.1
Odaka, A.2
Suzuki, N.3
Ihara, Y.4
-
21
-
-
0030775361
-
Amyloid beta-protein (Abeta) 1-40 but not Abeta1-42 contributes to the experimental formation of Alzheimer disease amyloid fibrils in rat brain
-
R.W. Shin, K. Ogino, A. Kondo, T.C. Saido, J.Q. Trojanowski, T. Kitamoto, and J. Tateishi Amyloid beta-protein (Abeta) 1-40 but not Abeta1-42 contributes to the experimental formation of Alzheimer disease amyloid fibrils in rat brain J Neurosci 17 1997 8187 8193
-
(1997)
J Neurosci
, vol.17
, pp. 8187-8193
-
-
Shin, R.W.1
Ogino, K.2
Kondo, A.3
Saido, T.C.4
Trojanowski, J.Q.5
Kitamoto, T.6
Tateishi, J.7
-
22
-
-
0142241380
-
Amyloid beta-protein (Abeta)1-40 protects neurons from damage induced by Abeta1-42 in culture and in rat brain
-
K. Zou, D. Kim, A. Kakio, K. Byun, J.S. Gong, J. Kim, M. Kim, N. Sawamura, S. Nishimoto, K. Matsuzaki, B. Lee, K. Yanagisawa, and M. Michikawa Amyloid beta-protein (Abeta)1-40 protects neurons from damage induced by Abeta1-42 in culture and in rat brain J Neurochem 87 2003 609 619
-
(2003)
J Neurochem
, vol.87
, pp. 609-619
-
-
Zou, K.1
Kim, D.2
Kakio, A.3
Byun, K.4
Gong, J.S.5
Kim, J.6
Kim, M.7
Sawamura, N.8
Nishimoto, S.9
Matsuzaki, K.10
Lee, B.11
Yanagisawa, K.12
Michikawa, M.13
-
23
-
-
33947242870
-
When loss is gain: Reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking point on the role of presenilin mutations in Alzheimer disease
-
M.S. Wolfe When loss is gain: reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking point on the role of presenilin mutations in Alzheimer disease EMBO Rep 8 2007 136 140
-
(2007)
EMBO Rep
, vol.8
, pp. 136-140
-
-
Wolfe, M.S.1
-
24
-
-
0028102078
-
Naturally occurring active N-domain of human angiotensin I-converting enzyme
-
P.A. Deddish, J. Wang, B. Michel, P.W. Morris, N.O. Davidson, R.A. Skidgel, and E.G. Erdos Naturally occurring active N-domain of human angiotensin I-converting enzyme Proc Natl Acad Sci USA 91 1994 7807 7811
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7807-7811
-
-
Deddish, P.A.1
Wang, J.2
Michel, B.3
Morris, P.W.4
Davidson, N.O.5
Skidgel, R.A.6
Erdos, E.G.7
-
26
-
-
77957785420
-
Neurotoxicity of Alzheimer's disease Abeta peptides is induced by small changes in the Abeta42 to Abeta40 ratio
-
I. Kuperstein, K. Broersen, I. Benilova, J. Rozenski, W. Jonckheere, M. Debulpaep, A. Vandersteen, I. Segers-Nolten, K. Van Der Werf, V. Subramaniam, D. Braeken, G. Callewaert, C. Bartic, R. D'Hooge, I.C. Martins, F. Rousseau, J. Schymkowitz, and B. De Strooper Neurotoxicity of Alzheimer's disease Abeta peptides is induced by small changes in the Abeta42 to Abeta40 ratio EMBO J 29 2010 3408 3420
-
(2010)
EMBO J
, vol.29
, pp. 3408-3420
-
-
Kuperstein, I.1
Broersen, K.2
Benilova, I.3
Rozenski, J.4
Jonckheere, W.5
Debulpaep, M.6
Vandersteen, A.7
Segers-Nolten, I.8
Van Der Werf, K.9
Subramaniam, V.10
Braeken, D.11
Callewaert, G.12
Bartic, C.13
D'Hooge, R.14
Martins, I.C.15
Rousseau, F.16
Schymkowitz, J.17
De Strooper, B.18
|