Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in alzheimer disease

Journal of Biological Chemistry

Volumn 288, Issue 21, 2013, Pages 15418-15429

  Tavares, Ignatius A ^a   Touma, Dona ^a   Lynham, Steven ^a   Troakes, Claire ^a   Schober, Megan ^a   Causevic, Mirsada ^a   Garg, Ritu ^b   Noble, Wendy ^a   Killick, Richard ^a   Bodi, Istvan ^c   Hanger, Diane P ^a   Morris, Jonathan D H ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ENTORHINAL CORTEX; HUMAN BRAIN; MASS SPECTROMETRIC ANALYSIS; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE STABILITY; NEUROFIBRILLARY TANGLES; TAU PROTEINS;

BINDING SITES; BRAIN; NEURODEGENERATIVE DISEASES; NEURONS; PATHOLOGY; PHOSPHORYLATION; UROLOGY;

ENZYMES;

PROSTATE DERIVED STERILE 20 LIKE KINASE 1; PROSTATE DERIVED STERILE 20 LIKE KINASE 2; PROTEIN KINASE; TAU PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN NERVE CELL; BRAIN TISSUE; CATALYSIS; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; ENTORHINAL CORTEX; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MALE; MASS SPECTROMETRY; MICROTUBULE; NEURITE; NEUROFIBRILLARY TANGLE; NEUROPIL THREAD; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION;

ALZHEIMER DISEASE; KINASE; MAP KINASES (MAPKS); MAPS; NEURODEGENERATIVE DISEASES; NEUROFIBRILLARY TANGLES; PHOSPHORYLATION; PSK KINASES; SIGNAL TRANSDUCTION; TAU;

ALZHEIMER DISEASE; AMINO ACID MOTIFS; ANIMALS; CERCOPITHECUS AETHIOPS; CEREBELLUM; COS CELLS; ENTORHINAL CORTEX; FEMALE; HIPPOCAMPUS; HUMANS; MALE; MAP KINASE KINASE KINASES; NEURONS; PHOSPHORYLATION; TAU PROTEINS;

EID: 84878234937     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.448183     Document Type: Article

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