Prostate-derived sterile 20-like kinase 1-α induces apoptosis: JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing

Journal of Biological Chemistry

Volumn 282, Issue 9, 2007, Pages 6484-6493

  Zihni, Ceniz ^a,c   Mitsopoulos, Costas ^a,c   Tavares, Ignatius A ^a,c   Baum, Buzz ^b,c   Ridley, Anne J ^b,c   Morris, Jonathan D H ^a,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MICROTUBULE-DISRUPTING AGENTS; MICROTUBULES; NUCLEAR LOCALIZATION; TRANSLOCATION;

BINDING ENERGY; CATALYST ACTIVITY; CELL DEATH; CELL MEMBRANES; MUTAGENESIS;

ENZYMES;

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 9; CASPASE INHIBITOR; ISOENZYME; PHOSPHOSERINE; PROSTATE DERIVED STERILE 20 LIKE KINASE 1 ALPHA; PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; CASPASE; PROSTATE DERIVED STE20 LIKE KINASE; PROSTATE-DERIVED STE20-LIKE KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL MEMBRANE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MEMBRANE BIOLOGY; MICROTUBULE; MOLECULAR RECOGNITION; MUSCLE FIBER CONTRACTION; MUTATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN MOTIF; ACTIVE TRANSPORT; ANIMAL; CELL SHAPE; GENETIC TRANSFECTION; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL MEMBRANE; CELL SHAPE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASES; TRANSFECTION;

EID: 34250318632     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608336200     Document Type: Article

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