Transfer of HBV genomes using low doses of adenovirus vectors leads to persistent infection in immune competent mice

Gastroenterology

Volumn 142, Issue 7, 2012, Pages

  Huang, Li Rung ^a   Gäbel, Yvonne A ^a   Graf, Steffi ^b   Arzberger, Silke ^b   Kurts, Christian ^a   Heikenwalder, Mathias ^b   Knolle, Percy A ^a   Protzer, Ulrike ^b,c  

^a UNIVERSITY OF BONN   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c German Center for Infection Research   (Germany)

Author keywords

Immunity; Liver Disease; Mouse Model; Virology

Indexed keywords

ADENOVIRUS VECTOR;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA IMMUNIZATION; HEPATITIS B; HEPATITIS B VIRUS; IMMUNOCOMPETENCE; IN VIVO GENE TRANSFER; MOUSE; NONHUMAN; PERSISTENT HEPATITIS B INFECTION; PERSISTENT INFECTION; PRIORITY JOURNAL; SEROCONVERSION; VIRAL CLEARANCE; VIRUS GENOME;

EID: 84861591942     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.03.006     Document Type: Article

References (18)

1. M.F. Sprinzl J Virol 75 2001 5108 5118
2. P.L. Yang Proc Natl Acad Sci U S A 99 2002 13825 13830
3. Y.J. Lin Proc Natl Acad Sci U S A 107 2010 9340 9345
4. M.J. von Freyend J Viral Hepat 18 2011 216 226
5. S. Asabe J Virol 83 2009 9652 9662
6. P.L. Yang Proc Natl Acad Sci U S A 107 2010 798 802
7. M. Isogawa Virology 333 2005 293 300
8. D. Stabenow Hepatology 51 2010 1430 1437
9. L.G. Guidotti Science 284 1999 825 829
10. H.T. Jin Proc Natl Acad Sci U S A 107 2010 14733 14738
11. P. Fisicaro Gastroenterology 138 2010 682 693 e1-4
12. G. Bocharov J Virol 78 2004 2247 2254
13. M. Hosel Hepatology 50 2009 1773 1782
14. Z. Racz Nucleic Acid Ther 21 2011 215 224
15. Z.C. Hartman J Virol 81 2007 1796 1812
16. J.M. von Freyend J Viral Hepat 18 2011 216 226
17. J. Dumortier Gene Ther 12 2005 668 677
18. G. Widera J Immunol 164 2000 4635 4640