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Volumn 62, Issue 6, 2013, Pages 1843-1854

Reduced adipose tissue macrophage content is associated with improved insulin sensitivity in thiazolidinedione-treated diabetic humans

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; C PEPTIDE; CD14 ANTIGEN; CD68 ANTIGEN; COLONY STIMULATING FACTOR 1; FATTY ACID; GLUCOSE; HERMES ANTIGEN; HYALURONIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 10; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PIOGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84878221256     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0868     Document Type: Article
Times cited : (79)

References (43)
  • 3
    • 34247857663 scopus 로고    scopus 로고
    • Obesity, Inflammation, and Insulin Resistance
    • DOI 10.1053/j.gastro.2007.03.059, PII S0016508507005859
    • Shoelson SE, Herrero L, Naaz A. Obesity, inflammation, and insulin resistance. Gastroenterology 2007;132:2169-2180 (Pubitemid 46693756)
    • (2007) Gastroenterology , vol.132 , Issue.6 , pp. 2169-2180
    • Shoelson, S.E.1    Herrero, L.2    Naaz, A.3
  • 4
    • 34748901835 scopus 로고    scopus 로고
    • Increased expression of the macrophage markers and of 11β-HSD-1 in subcutaneous adipose tissue, but not in cultured monocyte-derived macrophages, is associated with liver fat in human obesity
    • DOI 10.1038/sj.ijo.0803635, PII 0803635
    • Makkonen J, Westerbacka J, Kolak M, et al. Increased expression of the macrophage markers and of 11beta-HSD-1 in subcutaneous adipose tissue, but not in cultured monocyte-derived macrophages, is associated with liver fat in human obesity. Int J Obes (Lond) 2007;31:1617-1625 (Pubitemid 47482653)
    • (2007) International Journal of Obesity , vol.31 , Issue.10 , pp. 1617-1625
    • Makkonen, J.1    Westerbacka, J.2    Kolak, M.3    Sutinen, J.4    Corner, A.5    Hamsten, A.6    Fisher, R.M.7    Yki-Jarvinen, H.8
  • 7
    • 0035023128 scopus 로고    scopus 로고
    • Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
    • Kern PA, Ranganathan S, Li C, Wood L, Ranganathan G. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 2001;280:E745-E751
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Kern, P.A.1    Ranganathan, S.2    Li, C.3    Wood, L.4    Ranganathan, G.5
  • 9
    • 48249117202 scopus 로고    scopus 로고
    • Blockade of alpha4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity
    • Féral CC, Neels JG, Kummer C, Slepak M, Olefsky JM, Ginsberg MH. Blockade of alpha4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity. Diabetes 2008;57:1842-1851
    • (2008) Diabetes , vol.57 , pp. 1842-1851
    • Féral, C.C.1    Neels, J.G.2    Kummer, C.3    Slepak, M.4    Olefsky, J.M.5    Ginsberg, M.H.6
  • 10
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • Kanda H, Tateya S, Tamori Y, et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 2006;116:1494-1505
    • (2006) J Clin Invest , vol.116 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3
  • 11
    • 84856533216 scopus 로고    scopus 로고
    • Increased macrophage migration into adipose tissue in obese mice
    • Oh DY, Morinaga H, Talukdar S, Bae EJ, Olefsky JM. Increased macrophage migration into adipose tissue in obese mice. Diabetes 2012;61:346-354
    • (2012) Diabetes , vol.61 , pp. 346-354
    • Oh, D.Y.1    Morinaga, H.2    Talukdar, S.3    Bae, E.J.4    Olefsky, J.M.5
  • 13
    • 63249106129 scopus 로고    scopus 로고
    • Macrophage content in subcutaneous adipose tissue: Associations with adiposity, age, inflammatory markers, and whole-body insulin action in healthy Pima Indians
    • Ortega Martinez de Victoria E, Xu X, Koska J, et al. Macrophage content in subcutaneous adipose tissue: associations with adiposity, age, inflammatory markers, and whole-body insulin action in healthy Pima Indians. Diabetes 2009;58:385-393
    • (2009) Diabetes , vol.58 , pp. 385-393
    • Ortega Martinez De Victoria, E.1    Xu, X.2    Koska, J.3
  • 14
    • 77956365306 scopus 로고    scopus 로고
    • Short-term overfeeding may induce peripheral insulin resistance without altering subcutaneous adipose tissue macrophages in humans
    • Tam CS, Viardot A, Clément K, et al. Short-term overfeeding may induce peripheral insulin resistance without altering subcutaneous adipose tissue macrophages in humans. Diabetes 2010;59:2164-2170
    • (2010) Diabetes , vol.59 , pp. 2164-2170
    • Tam, C.S.1    Viardot, A.2    Clément, K.3
  • 16
    • 34548402222 scopus 로고    scopus 로고
    • Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion
    • DOI 10.2337/db07-0218
    • Han CY, Subramanian S, Chan CK, et al. Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion. Diabetes 2007;56:2260-2273 (Pubitemid 47358233)
    • (2007) Diabetes , vol.56 , Issue.9 , pp. 2260-2273
    • Chang, Y.H.1    Subramanian, S.2    Chan, C.K.3    Omer, M.4    Chiba, T.5    Wight, T.N.6    Chait, A.7
  • 17
    • 54049086276 scopus 로고    scopus 로고
    • Interferon-gamma, a Th1 cytokine, regulates fat inflammation: A role for adaptive immunity in obesity
    • Rocha VZ, Folco EJ, Sukhova G, et al. Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity. Circ Res 2008;103:467-476
    • (2008) Circ Res , vol.103 , pp. 467-476
    • Rocha, V.Z.1    Folco, E.J.2    Sukhova, G.3
  • 18
    • 0034890103 scopus 로고    scopus 로고
    • Physiological role of adipose tissue: White adipose tissue as an endocrine and secretory organ
    • Trayhurn P, Beattie JH. Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc 2001;60:329-339 (Pubitemid 32772448)
    • (2001) Proceedings of the Nutrition Society , vol.60 , Issue.3 , pp. 329-339
    • Trayhurn, P.1    Beattie, J.H.2
  • 19
    • 79551529432 scopus 로고    scopus 로고
    • Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers
    • Deiuliis J, Shah Z, Shah N, et al. Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers. PLoS ONE 2011;6:e16376
    • (2011) PLoS ONE , vol.6
    • Deiuliis, J.1    Shah, Z.2    Shah, N.3
  • 20
    • 80755168875 scopus 로고    scopus 로고
    • Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy
    • Eller K, Kirsch A, Wolf AM, et al. Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy. Diabetes 2011;60:2954-2962
    • (2011) Diabetes , vol.60 , pp. 2954-2962
    • Eller, K.1    Kirsch, A.2    Wolf, A.M.3
  • 21
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
    • Feuerer M, Herrero L, Cipolletta D, et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009;15:930-939
    • (2009) Nat Med , vol.15 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3
  • 22
    • 79953204947 scopus 로고    scopus 로고
    • Inflammation correlates with markers of T-cell subsets including regulatory T cells in adipose tissue from obese patients
    • Zeyda M, Huber J, Prager G, Stulnig TM. Inflammation correlates with markers of T-cell subsets including regulatory T cells in adipose tissue from obese patients. Obesity (Silver Spring) 2011;19:743-748
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 743-748
    • Zeyda, M.1    Huber, J.2    Prager, G.3    Stulnig, T.M.4
  • 23
    • 53149119231 scopus 로고    scopus 로고
    • Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding
    • Elgazar-Carmon V, Rudich A, Hadad N, Levy R. Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. J Lipid Res 2008;49:1894-1903
    • (2008) J Lipid Res , vol.49 , pp. 1894-1903
    • Elgazar-Carmon, V.1    Rudich, A.2    Hadad, N.3    Levy, R.4
  • 24
    • 84865460082 scopus 로고    scopus 로고
    • Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-ssociated increases in CD11c+ cells in adipose tissue and liver
    • Stefanovic-Racic M, Yang X, Turner MS, et al. Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-ssociated increases in CD11c+ cells in adipose tissue and liver. Diabetes 2012;61:2330-2339
    • (2012) Diabetes , vol.61 , pp. 2330-2339
    • Stefanovic-Racic, M.1    Yang, X.2    Turner, M.S.3
  • 25
    • 84863492238 scopus 로고    scopus 로고
    • Effect of insulin sensitizer therapy on atherothrombotic and inflammatory profiles associated with insulin resistance
    • McCoy RG, Irving BA, Soop M, et al. Effect of insulin sensitizer therapy on atherothrombotic and inflammatory profiles associated with insulin resistance. Mayo Clinic Proc Clinic 2012;87:561-570
    • (2012) Mayo Clinic Proc Clinic , vol.87 , pp. 561-570
    • McCoy, R.G.1    Irving, B.A.2    Soop, M.3
  • 27
    • 23644446750 scopus 로고    scopus 로고
    • Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: Association with cytokine expression, insulin resistance, and reduction by pioglitazone
    • DOI 10.2337/diabetes.54.8.2305
    • Di Gregorio GB, Yao-Borengasser A, Rasouli N, et al. Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone. Diabetes 2005;54:2305-2313 (Pubitemid 41134256)
    • (2005) Diabetes , vol.54 , Issue.8 , pp. 2305-2313
    • Di, G.G.B.1    Yao-Borengasser, A.2    Rasouli, N.3    Varma, V.4    Lu, T.5    Miles, L.M.6    Ranganathan, G.7    Peterson, C.A.8    McGehee, R.E.9    Kern, P.A.10
  • 28
    • 0023708090 scopus 로고
    • Glucose disposal in obese non-diabetic and diabetic type II patients. A study by indirect calorimetry and euglycemic insulin clamp
    • Golay A, Defronzo RA, Thorin D, Jequier E, Felber JP. Glucose disposal in obese non-diabetic and diabetic type II patients. A study by indirect calorimetry and euglycemic insulin clamp. Diabete Metab 1988;14:443-451
    • (1988) Diabete Metab , vol.14 , pp. 443-451
    • Golay, A.1    Defronzo, R.A.2    Thorin, D.3    Jequier, E.4    Felber, J.P.5
  • 29
    • 84055184949 scopus 로고    scopus 로고
    • Activation of K(ATP) channels suppresses glucose production in humans
    • Kishore P, Boucai L, Zhang K, et al. Activation of K(ATP) channels suppresses glucose production in humans. J Clin Invest 2011;121:4916-4920
    • (2011) J Clin Invest , vol.121 , pp. 4916-4920
    • Kishore, P.1    Boucai, L.2    Zhang, K.3
  • 31
    • 0036307329 scopus 로고    scopus 로고
    • Glycemic control determines hepatic and peripheral glucose effectiveness in type 2 diabetic subjects
    • Hawkins M, Gabriely I, Wozniak R, Reddy K, Rossetti L, Shamoon H. Glycemic control determines hepatic and peripheral glucose effectiveness in type 2 diabetic subjects. Diabetes 2002;51:2179-2189 (Pubitemid 34729023)
    • (2002) Diabetes , vol.51 , Issue.7 , pp. 2179-2189
    • Hawkins, M.1    Gabriely, I.2    Wozniak, R.3    Reddy, K.4    Rossetti, L.5    Shamoon, H.6
  • 32
    • 80355133234 scopus 로고    scopus 로고
    • Macrophage-mediated inflammation in metabolic disease
    • Chawla A, Nguyen KD, Goh YP. Macrophage-mediated inflammation in metabolic disease. Nat Rev Immunol 2011;11:738-749
    • (2011) Nat Rev Immunol , vol.11 , pp. 738-749
    • Chawla, A.1    Nguyen, K.D.2    Goh, Y.P.3
  • 33
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • DOI 10.1038/nri978
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003;3:23-35 (Pubitemid 37328697)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 34
    • 0035985758 scopus 로고    scopus 로고
    • Roles of peroxisome proliferator-activated receptor gamma in lipid homeostasis and inflammatory responses of macrophages
    • DOI 10.1097/00041433-200206000-00011
    • Klappacher GW, Glass CK. Roles of peroxisome proliferator-activated receptor gamma in lipid homeostasis and in flammatory responses of macrophages. Curr Opin Lipidol 2002;13:305-312 (Pubitemid 34592288)
    • (2002) Current Opinion in Lipidology , vol.13 , Issue.3 , pp. 305-312
    • Klappacher, G.W.1    Glass, C.K.2
  • 36
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARgamma
    • Tontonoz P, Spiegelman BM. Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem 2008;77:289-312
    • (2008) Annu Rev Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 37
    • 8444233254 scopus 로고    scopus 로고
    • Nuclear receptors in macrophage biology: At the crossroads of lipid metabolism and inflammation
    • DOI 10.1146/annurev.cellbio.20.012103.134432
    • Castrillo A, Tontonoz P. Nuclear receptors in macrophage biology: at the crossroads of lipid metabolism and inflammation. Annu Rev Cell Dev Biol 2004;20:455-480 (Pubitemid 39488646)
    • (2004) Annual Review of Cell and Developmental Biology , vol.20 , pp. 455-480
    • Castrillo, A.1    Tontonoz, P.2
  • 38
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • DOI 10.1038/34178
    • Ricote M, Li AC,Willson TM, Kelly CJ, Glass CK. The peroxisome proliferatoractivated receptor-gamma is a negative regulator of macrophage activation. Nature 1998;391:79-82 (Pubitemid 28079218)
    • (1998) Nature , vol.391 , Issue.6662 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 40
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • DOI 10.1016/j.it.2004.09.015, PII S1471490604002959
    • Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 2004;25:677-686 (Pubitemid 39457982)
    • (2004) Trends in Immunology , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 41
    • 21244443731 scopus 로고    scopus 로고
    • Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
    • Stout RD, Jiang C, Matta B, Tietzel I, Watkins SK, Suttles J. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol 2005;175:342-349 (Pubitemid 40884337)
    • (2005) Journal of Immunology , vol.175 , Issue.1 , pp. 342-349
    • Stout, R.D.1    Jiang, C.2    Matta, B.3    Tietzel, I.4    Watkins, S.K.5    Suttles, J.6
  • 42
    • 84872041568 scopus 로고    scopus 로고
    • A potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammation
    • Zhong J, Rao X, Deiuliis J, et al. A potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammation. Diabetes 2013;62:149-157
    • (2013) Diabetes , vol.62 , pp. 149-157
    • Zhong, J.1    Rao, X.2    Deiuliis, J.3
  • 43
    • 65649117802 scopus 로고    scopus 로고
    • Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity
    • Duffaut C, Galitzky J, Lafontan M, Bouloumié A. Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity. Biochem Biophys Res Commun 2009;384:482-485
    • (2009) Biochem Biophys Res Commun , vol.384 , pp. 482-485
    • Duffaut, C.1    Galitzky, J.2    Lafontan, M.3    Bouloumié, A.4


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