Ku80-deleted cells are defective at base excision repair

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 745-746, Issue , 2013, Pages 16-25

  Li, Han ^a,b   Marple, Teresa ^a   Hasty, Paul ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Structural Biology and Biocomputing Programme   (Spain)

Author keywords

Base excision repair; Base lesions; Double strand breaks; Nonhomologous end joining; Single strand breaks

Indexed keywords

ALKYLATING AGENT; DNA BINDING PROTEIN; DNA LIGASE IV; HISTONE H2AX; KU ANTIGEN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN KU80; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; CELL MUTANT; CONTROLLED STUDY; DNA END JOINING REPAIR; DNA SYNTHESIS; DOUBLE STRANDED DNA BREAK; DRUG HYPERSENSITIVITY; EXCISION REPAIR; GENE DELETION; PRIORITY JOURNAL; SINGLE STRANDED DNA BREAK;

ALKYLATING AGENTS; ANIMALS; ANTIGENS, NUCLEAR; BASE SEQUENCE; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA GLYCOSYLASES; DNA LIGASES; DNA REPAIR; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; MICE; MOLECULAR SEQUENCE DATA; MUTAGENS; MUTATION; PARAQUAT; REACTIVE OXYGEN SPECIES;

EID: 84878218838     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2013.03.010     Document Type: Article

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