A simplified radiometabolite analysis procedure for PET radioligands using a solid phase extraction with micellar medium

Nuclear Medicine and Biology

Volumn 40, Issue 5, 2013, Pages 658-663

  Nakao, Ryuji ^a   Halldin, Christer ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Direct plasma analysis; Micellar eluent; Positron emission tomography (PET); Radiometabolite analysis; Solid phase extraction

Indexed keywords

CARBON 11; DEPRENYL D2 C 11; DODECYL SULFATE SODIUM; DRUG METABOLITE; ORM 13070 C 11; PBR 28 C 11; PLASMA PROTEIN; RADIOLIGAND; RADIOMETABOLITE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BLOOD SAMPLING; DRUG BLOOD LEVEL; DRUG METABOLISM; DRUG PROTEIN BINDING; HAPLORHINI; HUMAN; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MICELLE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; QUANTITATIVE ANALYSIS; RADIOACTIVITY; SENSITIVITY ANALYSIS; SOLID PHASE EXTRACTION;

ANIMALS; CARBON RADIOISOTOPES; FEMALE; HUMANS; LIGANDS; MACACA FASCICULARIS; MICELLES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; SURFACE-ACTIVE AGENTS; TIME FACTORS;

EID: 84878194644     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2013.02.007     Document Type: Article

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