Fast high performance liquid chromatography in PET quality control and metabolite analysis

Quarterly Journal of Nuclear Medicine and Molecular Imaging

Volumn 53, Issue 4, 2009, Pages 411-416

  Passchier, J ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Chromatography, high pressure liquid; Positron emission tomography; Quality control

Indexed keywords

CARBON 11; RADIOISOTOPE; TRACER;

ACCURACY; CONFERENCE PAPER; GOOD MANUFACTURING PRACTICE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; METABOLITE; POSITRON EMISSION TOMOGRAPHY; QUALITY CONTROL; QUANTITATIVE ANALYSIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG EVALUATION, PRECLINICAL; INTERNATIONALITY; POSITRON-EMISSION TOMOGRAPHY; QUALITY ASSURANCE, HEALTH CARE; RADIOPHARMACEUTICALS;

EID: 74949123198     PISSN: 18244785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (17)

1. Nakao R, Furutsuka K, Yamaguchi M, Suzuki K. Development and validation of a liquid chromatographic method for the analysis of positron emission tomography radiopharmaceuticals with Ru(bpy)(3)(2+)-KMnO(4) chemiluminescence detection. Anal Sci 2007;23:151-5.
2. Wren SA, Tchelitcheff P. Use of ultra-performance liquid chromatography in pharmaceutical development. J Chromatogr A 2006;1119:140-6.
3. Mazzeo JR, Neue UD, Kele M, Plumb RS. Advancing LC performance with smaller particles and higher pressure. Analytical Chemistry 2005;77:460A-467A.
4. Wu N, Clausen AM. Fundamental and practical aspects of ultrahigh pressure liquid chromatography for fast separations. J Sep Sci 2007;30:1167-82.
5. Zhu C, Goodall D, Wren SA. Elevated temperature HPLC: Principles and applications to small molecules and biomolecules. LCGC Europe 2004;17:530-40.
6. Lestremau F, de VA, Lynen F, Cooper A, Szucs R, Sandra P. High efficiency liquid chromatography on conventional columns and instrumentation by using temperature as a variable. Kinetic plots and experimental verification. J Chromatogr A 2007;113:120-31.
7. Cunliffe JM, Maloney TD. Fused-core particle technology as an alternative to sub-2-microm particles to achieve high separation efficiency with low backpressure. J Sep Sci 2007;30:3104-9.
8. Destefano JJ, Langlois TJ, Kirkland JJ. Characteristics of superficially-porous silica particles for fast HPLC: some performance comparisons with sub-2-microm particles. J Chromatogr Sci 2008;46:254-60.
9. Brice RW, Zhang X, Colon LA. Fused-core, sub-2 microm packings, and monolithic HPLC columns: a comparative evaluation. J Sep Sci 2009;32:2723-31.
10. Nakao R, Ito T, Hayashi K, Fukumura T, Yamaguchi M, Suzuki K. 1-Minute quality control tests for positron emission tomography radiopharmaceuticals. J Pharm Biomed Anal 2009;50:245-51.
11. Kroes R, Galli C, Munro I, Schilter B, Tran L, Walker R et al. Threshold of toxicological concern for chemical substances present in the diet: a practical tool for assessing the need for toxicity testing. Food Chem Toxicol 2000;38:255-312.
12. Cunningham VJ, Gunn RN, Matthews JC. Quantification in positron emission tomography for research in pharmacology and drug development. Nucl Med Commun 2004;25:643-6.
13. Schou M, Zoghbi SS, Shetty HU, Shchukin E, Liow JS, Hong J et al. Investigation of the metabolites of (S,S)-[(11)C]MeNER in humans, monkeys and rats. Mol Imaging Biol 2009;11:23-30.
14. Hilton J, Yokoi F, Dannals RF, Ravert HT, Szabo Z, Wong DF. Column-switching HPLC for the analysis of plasma in PET imaging studies. Nucl Med Biol. 2000;27(6):627-630.
15. Souverain S, Rudaz S, Veuthey JL. Restricted access materials and large particle supports for on-line sample preparation: an attractive approach for biological fluids analysis. J Chromatogr B Analyt Technol Biomed Life Sci 2004;801:141-56.
16. Souverain S, Rudaz S, Veuthey JL. Use of monolithic supports for fast analysis of drugs and metabolites in plasma by direct injection. Chromatographia 2003;57:569-75.
17. Shetty HU, Chin FT, Musachio JL, Pike VW. Use of LC-MS-MS for the rapid, specific and sensitive quality control measurement of carrier in a PET radioligand: [18F]FECNT. J Label Compd Radiopharm 2005;48:940.