Genetic manipulations restored the growth fitness of reduced-genome Escherichia coli

Journal of Bioscience and Bioengineering

Volumn 116, Issue 1, 2013, Pages 52-58

  Hirokawa, Yasutaka ^a,c   Kawano, Hiroaki ^a,d   Tanaka Masuda, Kimie ^a   Nakamura, Noriko ^a   Nakagawa, Akira ^a,e   Ito, Mikito ^a,f   Mori, Hideo ^a   Oshima, Taku ^b   Ogasawara, Naotake ^b  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c WASEDA UNIVERSITY   (Japan)

^d OSAKA MEDICAL COLLEGE   (Japan)

^e ISHIKAWA PREFECTURAL UNIVERSITY   (Japan)

^f Kyowa Hakko Bio Co Ltd   (Japan)

Author keywords

Escherichia coli; Genome reduction; Metabolic engineering; Molecular breeding; Synthetic biology

Indexed keywords

DOWN-REGULATION; GENES ENCODING; GENETIC MANIPULATIONS; INSERTION SEQUENCES; MOLECULAR BREEDING; STRAIN CONSTRUCTIONS; SYNTHETIC BIOLOGY; TRANSCRIPTOME ANALYSIS;

ENCODING (SYMBOLS); ESCHERICHIA COLI; HEALTH; METABOLIC ENGINEERING; RESTORATION;

GENES;

8 DIFLUOROMETHOXY 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 4 OXO 3 QUINOLINECARBOXYLIC ACID; CHAPERONE; PROTEINASE; TRANSCRIPTOME;

ARTICLE; AUXOTROPHY; BACTERIAL STRAIN; CONTROLLED STUDY; DOWN REGULATION; ESCHERICHIA COLI; GENE INSERTION SEQUENCE; GENE SEQUENCE; GENETIC MANIPULATION; GENOME SIZE; INOCULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; WILD TYPE;

DNA REPAIR; DOWN-REGULATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION PROFILING; GENOME SIZE; GENOME, BACTERIAL; METABOLIC ENGINEERING; MOLECULAR CHAPERONES; MUTATION;

ESCHERICHIA COLI; ESCHERICHIA COLI K12;

EID: 84878186034     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2013.01.010     Document Type: Article

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