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Volumn 31, Issue 7, 2013, Pages 1067-1074

Sheep model for osteoporosis: Sustainability and biomechanical relevance of low turnover osteoporosis induced by hypothalamic-pituitary disconnection

Author keywords

hypothalamic pituitary disconnection (HPD); large animal model; low turnover; osteoporosis; sheep

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; CALCIUM;

EID: 84878171413     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22327     Document Type: Article
Times cited : (28)

References (39)
  • 2
    • 0029976494 scopus 로고    scopus 로고
    • Osteoporosis: Frequency, consequences, and risk factors
    • DOI 10.1001/archinte.156.13.1399
    • Ross PD., 1996. Osteoporosis. Frequency, consequences, and risk factors. Arch Intern Med 156: 1399-1411. (Pubitemid 26226934)
    • (1996) Archives of Internal Medicine , vol.156 , Issue.13 , pp. 1399-1411
    • Ross, P.D.1
  • 3
    • 33750209491 scopus 로고    scopus 로고
    • An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
    • DOI 10.1007/s00198-006-0172-4
    • Johnell O, Kanis JA., 2006. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 17: 1726-1733. (Pubitemid 44607392)
    • (2006) Osteoporosis International , vol.17 , Issue.12 , pp. 1726-1733
    • Johnell, O.1    Kanis, J.A.2
  • 4
    • 0028785711 scopus 로고
    • FDA Guidelines and animal models for osteoporosis
    • Thompson DD, Simmons HA, Pirie CM, et al. 1995. FDA Guidelines and animal models for osteoporosis. Bone 17: 125S-133S.
    • (1995) Bone , vol.17
    • Thompson, D.D.1    Simmons, H.A.2    Pirie, C.M.3
  • 5
    • 0348110422 scopus 로고    scopus 로고
    • Guidelines for the development of anti-osteoporosis medications
    • Avouac B., 2003. Guidelines for the development of anti-osteoporosis medications. Therapie 58: 421-424.
    • (2003) Therapie , vol.58 , pp. 421-424
    • Avouac, B.1
  • 6
    • 0028839450 scopus 로고
    • Changes in bone mineral density and bone-specific alkaline phosphatase in ovariectomized ewes
    • Turner AS, Alvis M, Myers W, et al. 1995. Changes in bone mineral density and bone-specific alkaline phosphatase in ovariectomized ewes. Bone 17: 395S-402S.
    • (1995) Bone , vol.17
    • Turner, A.S.1    Alvis, M.2    Myers, W.3
  • 7
    • 0029093747 scopus 로고
    • Interruption of disuse by short duration walking exercise does not prevent bone loss in the sheep calcaneus
    • Skerry TM, Lanyon LE., 1995. Interruption of disuse by short duration walking exercise does not prevent bone loss in the sheep calcaneus. Bone 16: 269-274.
    • (1995) Bone , vol.16 , pp. 269-274
    • Skerry, T.M.1    Lanyon, L.E.2
  • 8
    • 0036304837 scopus 로고    scopus 로고
    • Effect of ovariectomy, malnutrition and glucocorticoid application on bone properties in sheep: A pilot study
    • DOI 10.1007/s001980200058
    • Lill CA, Fluegel AK, Schneider E., 2002. Effect of ovariectomy, malnutrition and glucocorticoid application on bone properties in sheep: a pilot study. Osteoporos Int 13: 480-486. (Pubitemid 34742207)
    • (2002) Osteoporosis International , vol.13 , Issue.6 , pp. 480-486
    • Lill, C.A.1    Lill, C.A.2    Fluegel, A.K.3    Schneider, E.4
  • 11
    • 77249099402 scopus 로고    scopus 로고
    • Glucocorticoid induced osteopenia in cancellous bone of sheep: Validation of large animal model for spine fusion and biomaterial research
    • Ding M, Cheng L, Bollen P, et al. 2010. Glucocorticoid induced osteopenia in cancellous bone of sheep: validation of large animal model for spine fusion and biomaterial research. Spine (PhilaPa 1976) 35: 363-370.
    • (2010) Spine (PhilaPa 1976) , vol.35 , pp. 363-370
    • Ding, M.1    Cheng, L.2    Bollen, P.3
  • 12
    • 84861727801 scopus 로고    scopus 로고
    • Changes in osteocyte density correspond with changes in osteoblast and osteoclast activity in an osteoporotic sheep model
    • Zarrinkalam MR, Mulaibrahimovic A, Atkins GJ, et al. 2012. Changes in osteocyte density correspond with changes in osteoblast and osteoclast activity in an osteoporotic sheep model. Osteoporos Int 23: 1329-1336.
    • (2012) Osteoporos Int , vol.23 , pp. 1329-1336
    • Zarrinkalam, M.R.1    Mulaibrahimovic, A.2    Atkins, G.J.3
  • 13
    • 55049102015 scopus 로고    scopus 로고
    • A sheep model for fracture treatment in osteoporosis: Benefits of the model versus animal welfare
    • Egermann M, Goldhahn J, Holz R, et al. 2008. A sheep model for fracture treatment in osteoporosis: benefits of the model versus animal welfare. Lab Anim 42: 453-464.
    • (2008) Lab Anim , vol.42 , pp. 453-464
    • Egermann, M.1    Goldhahn, J.2    Holz, R.3
  • 15
    • 82055175647 scopus 로고    scopus 로고
    • Pinealectomy affects bone mineral density and structure - An experimental study in sheep
    • Egermann M, Gerhardt C, Barth A, et al. 2011. Pinealectomy affects bone mineral density and structure-an experimental study in sheep. BMC Musculoskelet Disord 12: 271.
    • (2011) BMC Musculoskelet Disord , vol.12 , pp. 271
    • Egermann, M.1    Gerhardt, C.2    Barth, A.3
  • 16
    • 84862757738 scopus 로고    scopus 로고
    • Low turnover osteoporosis in sheep induced by hypothalamic-pituitary disconnection
    • Beil FT, Oheim R, Barvencik F, et al. 2012. Low turnover osteoporosis in sheep induced by hypothalamic-pituitary disconnection. J Orthop Res. 30: 1254-1262.
    • (2012) J Orthop Res. , vol.30 , pp. 1254-1262
    • Beil, F.T.1    Oheim, R.2    Barvencik, F.3
  • 17
    • 0020570845 scopus 로고
    • Pituitary gland function after disconnection from direct hypothalamic influences in the sheep
    • Clarke IJ, Cummins JT, de Kretser DM., 1983. Pituitary gland function after disconnection from direct hypothalamic influences in the sheep. Neuroendocrinology 36: 376-384. (Pubitemid 13121958)
    • (1983) Neuroendocrinology , vol.36 , Issue.5 , pp. 376-384
    • Clarke, I.J.1    Cummins, J.T.2    De Kretser, D.M.3
  • 18
    • 0033303655 scopus 로고    scopus 로고
    • Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: Formal histomorphometric and biomechanical analyses
    • Amling M, Priemel M, Holzmann T, et al. 1999. Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: formal histomorphometric and biomechanical analyses. Endocrinology 140: 4982-4987.
    • (1999) Endocrinology , vol.140 , pp. 4982-4987
    • Amling, M.1    Priemel, M.2    Holzmann, T.3
  • 19
    • 0023488581 scopus 로고
    • Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt AM, Drezner MK, Glorieux FH, et al. 1987. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2: 595-610.
    • (1987) J Bone Miner Res , vol.2 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3
  • 20
    • 0028882234 scopus 로고
    • A new scanning electron microscopy approach to the quantification of bone mineral distribution: Backscattered electron image grey-levels correlated to calcium K alpha-line intensities
    • Roschger P, Plenk H Jr, Klaushofer K, et al. 1995. A new scanning electron microscopy approach to the quantification of bone mineral distribution: backscattered electron image grey-levels correlated to calcium K alpha-line intensities. Scan Microsc 9: 75.
    • (1995) Scan Microsc , vol.9 , pp. 75
    • Roschger, P.1    Plenk, Jr.H.2    Klaushofer, K.3
  • 21
    • 17644445505 scopus 로고    scopus 로고
    • Validation of quantitative backscattered electron imaging for the measurement of mineral density distribution in human bone biopsies
    • DOI 10.1016/S8756-3282(98)00112-4, PII S8756328298001124
    • Roschger P, Fratzl P, Eschberger J, et al. 1998. Validation of quantitative backscattered electron imaging for the measurement of mineral density distribution in human bone biopsies. Bone 23: 319-326. (Pubitemid 28454623)
    • (1998) Bone , vol.23 , Issue.4 , pp. 319-326
    • Roschger, P.1    Fratzl, P.2    Eschberger, J.3    Klaushofer, K.4
  • 22
    • 39149107458 scopus 로고    scopus 로고
    • Bone mineralization density distribution in health and disease
    • Roschger P, Paschalis EP, Fratzl P, et al. 2008. Bone mineralization density distribution in health and disease. Bone 42: 456-466.
    • (2008) Bone , vol.42 , pp. 456-466
    • Roschger, P.1    Paschalis, E.P.2    Fratzl, P.3
  • 23
    • 84861101861 scopus 로고    scopus 로고
    • Analysis of retrieved hip resurfacing arthroplasties reveals the interrelationship between interface hyperosteoidosis and demineralization of viable bone trabeculae
    • Breer S, Krause M, Busse B, et al. 2011. Analysis of retrieved hip resurfacing arthroplasties reveals the interrelationship between interface hyperosteoidosis and demineralization of viable bone trabeculae. J Orthop Res. 30: 1155-1161.
    • (2011) J Orthop Res. , vol.30 , pp. 1155-1161
    • Breer, S.1    Krause, M.2    Busse, B.3
  • 24
    • 0035166970 scopus 로고    scopus 로고
    • Effects of a new selective estrogen receptor modulator (MDL 103,323) on cancellous and cortical bone in ovariectomized ewes: A biochemical, histomorphometric, and densitometric study
    • Chavassieux P, Garnero P, Duboeuf F, et al. 2001. Effects of a new selective estrogen receptor modulator (MDL 103,323) on cancellous and cortical bone in ovariectomized ewes: a biochemical, histomorphometric, and densitometric study. J Bone Miner Res 16: 89-96. (Pubitemid 32046192)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.1 , pp. 89-96
    • Chavassieux, P.1    Garnero, P.2    Duboeuf, F.3    Vergnaud, P.4    Brunner-Ferber, F.5    Delmas, P.D.6    Meunier, P.J.7
  • 25
    • 53749087447 scopus 로고    scopus 로고
    • Implants delivering bisphosphonate locally increase periprosthetic bone density in an osteoporotic sheep model. A Pilot Study
    • Stadelmann VA, Gauthier O, Terrier A, et al. 2008. Implants delivering bisphosphonate locally increase periprosthetic bone density in an osteoporotic sheep model. A Pilot Study. Eur Cell Mater 16: 10-16.
    • (2008) Eur Cell Mater , vol.16 , pp. 10-16
    • Stadelmann, V.A.1    Gauthier, O.2    Terrier, A.3
  • 26
    • 77955773606 scopus 로고    scopus 로고
    • In vivo bone augmentation in an osteoporotic environment using bisphosphonate-loaded calcium deficient apatite
    • Verron E, Gauthier O, Janvier P, et al. 2010. In vivo bone augmentation in an osteoporotic environment using bisphosphonate-loaded calcium deficient apatite. Biomaterials 31: 7776-7784.
    • (2010) Biomaterials , vol.31 , pp. 7776-7784
    • Verron, E.1    Gauthier, O.2    Janvier, P.3
  • 27
    • 84865548798 scopus 로고    scopus 로고
    • Molecular engineering of an orthopaedic implant: From bench to bedside
    • Shapiro IM, Hickok NJ, Parvizi J, et al. 2012. Molecular engineering of an orthopaedic implant: from bench to bedside. Eur Cell Mater 23: 362-370.
    • (2012) Eur Cell Mater , vol.23 , pp. 362-370
    • Shapiro, I.M.1    Hickok, N.J.2    Parvizi, J.3
  • 28
    • 84858078004 scopus 로고    scopus 로고
    • The effects of bone marrow aspirate, bone graft, and collagen composites on fixation of titanium implants
    • Babiker H, Ding M, Sandri M, et al. 2012. The effects of bone marrow aspirate, bone graft, and collagen composites on fixation of titanium implants. J Biomed Mater Res B Appl Biomater 100: 759-766.
    • (2012) J Biomed Mater Res B Appl Biomater , vol.100 , pp. 759-766
    • Babiker, H.1    Ding, M.2    Sandri, M.3
  • 29
    • 0014443638 scopus 로고
    • Choice of animal models for the study of disease processes in man. Introduction
    • Frenkel JK., 1969. Choice of animal models for the study of disease processes in man. Introduction. Fed Proc 28: 160-161.
    • (1969) Fed Proc , vol.28 , pp. 160-161
    • Frenkel, J.K.1
  • 30
    • 50249160583 scopus 로고    scopus 로고
    • Review of nonprimate, large animal models for osteoporosis research
    • Reinwald S, Burr D., 2008. Review of nonprimate, large animal models for osteoporosis research. J Bone Miner Res 23: 1353-1368.
    • (2008) J Bone Miner Res , vol.23 , pp. 1353-1368
    • Reinwald, S.1    Burr, D.2
  • 31
    • 0034327227 scopus 로고    scopus 로고
    • Sheep model for fracture treatment in osteoporotic bone: A pilot study about different induction regimens
    • discussion 565-566.
    • Lill CA, Fluegel AK, Schneider E., 2000. Sheep model for fracture treatment in osteoporotic bone: a pilot study about different induction regimens. J Orthop Trauma 14: 559-565; discussion 565-566.
    • (2000) J Orthop Trauma , vol.14 , pp. 559-565
    • Lill, C.A.1    Fluegel, A.K.2    Schneider, E.3
  • 33
    • 84875499567 scopus 로고    scopus 로고
    • Large animal model for osteoporosis in humans: The ewe
    • Oheim R, Amling M, Ignatius A, et al. 2012. Large animal model for osteoporosis in humans: the ewe. Eur Cell Mater 24: 372-385.
    • (2012) Eur Cell Mater , vol.24 , pp. 372-385
    • Oheim, R.1    Amling, M.2    Ignatius, A.3
  • 35
    • 79955523143 scopus 로고    scopus 로고
    • Subchondral trabecular structural changes in the proximal tibia in an ovine model of increased bone turnover
    • Holland JC, Brennan O, Kennedy OD, et al. 2011. Subchondral trabecular structural changes in the proximal tibia in an ovine model of increased bone turnover. J Anat 218: 619-624.
    • (2011) J Anat , vol.218 , pp. 619-624
    • Holland, J.C.1    Brennan, O.2    Kennedy, O.D.3
  • 36
    • 59649120948 scopus 로고    scopus 로고
    • Effects of high bone turnover on the biomechanical properties of the L3 vertebra in an ovine model of early stage osteoporosis
    • Kennedy OD, Brennan O, Mahony NJ, et al. 2008. Effects of high bone turnover on the biomechanical properties of the L3 vertebra in an ovine model of early stage osteoporosis. Spine (PhilaPa 1976) 33: 2518-2523.
    • (2008) Spine (PhilaPa 1976) , vol.33 , pp. 2518-2523
    • Kennedy, O.D.1    Brennan, O.2    Mahony, N.J.3
  • 38
    • 59449090116 scopus 로고    scopus 로고
    • Validation of the sheep as a large animal model for the study of vertebral osteoporosis
    • Zarrinkalam MR, Beard H, Schultz CG, et al. 2009. Validation of the sheep as a large animal model for the study of vertebral osteoporosis. Eur Spine J 18: 244-253.
    • (2009) Eur Spine J , vol.18 , pp. 244-253
    • Zarrinkalam, M.R.1    Beard, H.2    Schultz, C.G.3
  • 39
    • 0033304832 scopus 로고    scopus 로고
    • Editorial: Cell number versus cell vigor - What really matters to a regenerating skeleton?
    • Manolagas SC., 1999. Cell number versus cell vigor-what really matters to a regenerating skeleton ? Endocrinology 140: 4377-4381. (Pubitemid 30666098)
    • (1999) Endocrinology , vol.140 , Issue.10 , pp. 4377-4381
    • Manolagas, S.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.