Effect of ovariectomy, malnutrition and glucocorticoid application on bone properties in sheep: A pilot study

Osteoporosis International

Volumn 13, Issue 6, 2002, Pages 480-486

  Lill, C A ^a,b   Fluegel, A K ^a   Schneider, E ^a  

^a AO RESEARCH INSTITUTE   (Switzerland)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Mechanical testing; Micro CT; Osteoporosis; Osteoporosis induction; pQCT; Sheep model

Indexed keywords

CALCIUM; GLUCOCORTICOID; METHYLPREDNISOLONE; VITAMIN D;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE; BONE DENSITY; BONE MINERAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; IMAGE ANALYSIS; MALNUTRITION; NONHUMAN; OSTEOPOROSIS; OVARIECTOMY; PRIORITY JOURNAL; SHEEP;

AGED; ANIMALS; BONE AND BONES; BONE DENSITY; CALCIUM; FEMALE; FRACTURES, BONE; GLUCOCORTICOIDS; HUMANS; METHYLPREDNISOLONE; MIDDLE AGED; MODELS, ANIMAL; NUTRITION DISORDERS; OSTEOPOROSIS, POSTMENOPAUSAL; OVARIECTOMY; PILOT PROJECTS; SHEEP; VITAMIN D DEFICIENCY;

EID: 0036304837     PISSN: 0937941X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001980200058     Document Type: Article

References (25)

1. The epidemiology of osteoporosis
2. Bone mineral density measured by dual-energy x-ray absorptiometry in healthy Finnish women
3. Intestinal calcium absorption in exogenous hypercortisolism: Role of 25-hydroxyvitamin D and corticosteroid dose
4. Bone histomorphometry in corticosteroid-induced osteoporosis and Cushing's syndrome
5. Short-term effects of corticosteroids on trabecular bone remodeling in old ewes
6. Effect of oophorectomy and calcium deprivation on bone mass in rat
7. The effect of ageing and changes in mineral content in degrading the toughness of human femora
8. Effects of ovariectomy on iliac trabecular bone in baboons
9. The potential of sheep for the study of osteopenia: Current status and comparison with other animal models
10. Sequential histomorphometric changes in cancellous bone from ovariohysterectomized dogs
11. Calcium-restricted ovariectomized Sinclair S-1 minipigs: An animal model of osteopenia and trabecular plate perforation
12. Changes in bone mineral density and bone-specific alkaline phosphatase in ovariectomized ewes
13. Effects of oophorectomy on biochemical and histological indices of bone turnover in ewes
14. Effect of salmon calcitonin on femoral bone quality in adult ovariectomized ewes
15. Sheep model for fracture treatment in osteoporotic bone: A pilot study about different induction regimens
16. Hormonal regulation of osteocalcin plasma production and clearance in sheep
17. Glucocorticoid-induced inhibition of osteoblastic bone formation in ewes: A biochemical and histomorphometric study
18. The effects on ewe bone remodeling of short-term sodium fluoride administration: A histomorphometric and biochemical study
19. Noninvasive assessment of bone mineral and structure: State of the art
20. Histomorphometric profile, pathophysiology and reversibility of corticosteroid-induced osteoporosis
21. Comparison between bone density and bone strength in glucocorticoid-treated aged ewes
22. Trabecular texture analysis of CT images in the relationship with spinal fracture
23. A standard test for laboratory animal bone
24. The effects of density and test conditions on measured compression and shear strength of cancellous bone from the lumbar vertebrae of ewes