Prima-1 induces apoptosis in bladder cancer cell lines by activating p53

Clinics

Volumn 68, Issue 3, 2013, Pages 297-303

  Piantino, Camila B ^a   Reis, Sabrina T ^a   Viana, Nayara I ^a   Silva, Iran A ^a   Morais, Denis R ^a   Antunes, Alberto A ^a   Dip, Nelson ^a   Srougi, Miguel ^a   Leite, Katia R ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Apoptosis; Bladder cancer; p53; Prima 1

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; PROTEIN P53; TUMOR PROTEIN;

ARTICLE; BLADDER TUMOR; CARCINOMA; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

APOPTOSIS REGULATORY PROTEINS; CARCINOMA; CELL LINE, TUMOR; GENE EXPRESSION; GENES, P53; HUMANS; MUTATION; NEOPLASM PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53; URINARY BLADDER NEOPLASMS;

EID: 84878159560     PISSN: 18075932     EISSN: None     Source Type: Journal    
DOI: 10.6061/clinics/2013(03)OA03     Document Type: Article

References (37)

1. INCA (2012). Accessed on October 6, 2012, http://www.inca.gov.br/estimativa/2012/.
2. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61(2):69-90, http://dx.doi.org/10.3322/caac.20107
3. Debra T. Silverman SSD, Lee E. Moore, Nathaniel Rothman. (2006) Bladder Cancer. In: David Schottenfeld JFF, Jr. (ed). Epidemiology and Prevention, 3 edn. Oxford University Press, New York, pp. 1101-1127.
4. Cote RJ, Datar RH. Therapeutic approaches to bladder cancer: identifying targets and mechanisms. Crit Rev Oncol Hematol. 2003;46 Suppl:S67-S83, http://dx.doi.org/10.1016/S1040-8428(03)00066-0.
5. Cordon-Cardo C. Molecular alterations associated with bladder cancer initiation and progression. Scand J Urol Nephrol Suppl. 2008;(218):154-165, http://dx.doi.org/10.1080/03008880802291915.
6. Cordon-Cardo C. Molecular alterations in bladder cancer. Cancer Surv. 1998;32:115-131.
7. Lu ML, Wikman F, Orntoft TF, Charytonowicz E, Rabbani F, Zhang Z, et al. Impact of alterations affecting the p53 pathway in bladder cancer on clinical outcome, assessed by conventional and array-based methods. Clin Cancer Res. 2002;8(1):171-179.
8. Feng Z, Hu W, Rom WN, Beland FA, Tang MS. 4-aminobiphenyl is a major etiological agent of human bladder cancer: evidence from its DNA binding spectrum in human p53 gene. Carcinogenesis. 2002;23(10):1721-1727, http://dx.doi.org/10.1093/carcin/23.10.1721.
9. Bykov VJ, Issaeva N, Shilov A, Hultcrantz M, Pugacheva E, Chumakov P, et al. Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound. Nat Med. 2002;8(3):282-288, http://dx.doi.org/10.1038/nm0302-282.
10. Batista LF, Kaina B, Meneghini R, Menck CF. How DNA lesions are turned into powerful killing structures: insights from UV-induced apoptosis. Mutat Res. 2009;681(2-3):197-208.
11. Szliszka E, Czuba ZP, Mazur B, Paradysz A, Krol W. Chalcones and dihydrochalcones augment TRAIL-mediated apoptosis in prostate cancer cells. Molecules. 2010;15(8):5336-5353, http://dx.doi.org/10.3390/molecules15085336.
12. Szliszka E, Zydowicz G, Janoszka B, Dobosz C, Kowalczyk-Ziomek G, Krol W. Ethanolic extract of Brazilian green propolis sensitizes prostate cancer cells to TRAIL-induced apoptosis. Int J Oncol. 2011;38(4):941-953.
13. Bieging KT, Attardi LD. Deconstructing p53 transcriptional networks in tumor suppression. Trends in cell biology. 2012;22(2):97-106, http://dx.doi.org/10.1016/j.tcb.2011.10.006.
14. Nakano K, Vousden KH. PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell. 2001;7(3):683-694, http://dx.doi.org/10.1016/S1097-2765(01)00214-3.
15. Jeffers JR, Parganas E, Lee Y, Yang C, Wang J, Brennan J, et al. Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell. 2003;4(4):321-328, http://dx.doi.org/10.1016/S1535-6108(03)00244-7.
16. Villunger A, Michalak EM, Coultas L, Mullauer F, Bock G, Ausserlechner MJ, et al. P53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science. 2003;302(5647):1036-8, http://dx.doi.org/10.1126/science.1090072.
17. Erlacher M, Michalak EM, Kelly PN, Labi V, Niederegger H, Coultas L, et al. BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation-and glucocorticoid-induced apoptosis of lymphoid cells in vivo. Blood. 2005;106(13):4131-8, http://dx.doi.org/10.1182/blood-2005-04-1595.
18. Shibue T, Takeda K, Oda E, Tanaka H, Murasawa H, Takaoka A, et al. Integral role of Noxa in p53-mediated apoptotic response. Genes Dev. 2003;17:2233-8, http://dx.doi.org/10.1101/gad.1103603.
19. Vousden KH. Apoptosis. p53 and PUMA: a deadly duo. Science. 2005;309(5741):1685-6, http://dx.doi.org/10.1126/science.1118232.
20. Lomonosova E, Ryerse J, Chinnadurai G. BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition? Mol Cancer Res. 2009;7(8):1268-1284, http://dx.doi.org/10.1158/1541-7786.MCR-08-0183.
21. Konstantakou EG, Voutsinas GE, Karkoulis PK, Aravantinos G, Margaritis LH, Stravopodis DJ. Human bladder cancer cells undergo cisplatin-induced apoptosis that is associated with p53-dependent and p53-independent responses. Int J Oncol. 2009;35(2):401-416.
22. Youle RJ, Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol. 2008;9(1):47-59, http://dx.doi.org/10.1038/nrm2308.
23. Lei X, Chen Y, Du G, Yu W, Wang X, Qu H, et al. Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2. FASEB J. 2006;20(12):2147-2149, http://dx.doi.org/10.1096/fj.05-5665fje.
24. Green DR. Apoptotic pathways: ten minutes to dead. Cell. 2006;121(5):671-4.
25. Claveria C, Martinez A C, Torres M. A Bax/Bak-independent mitochon-drial death pathway triggered by Drosophila Grim GH3 domain in mammalian cells. J Biol Chem. 2004;279(2):1368-1375.
26. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 1997;91(4):479-489, http://dx.doi.org/10.1016/S0092-8674(00)80434-1.
27. Budihardjo I, Oliver H, Lutter M, Luo X, Wang X. Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol. 1999;15:269-290, http://dx.doi.org/10.1146/annurev.cellbio.15.1.269.
28. Taylor RC, Cullen SP, Martin SJ. Apoptosis: controlled demolition at the cellular level. Nat Rev Mol Cell Biol. 2008;9(3):231-241, http://dx.doi.org/10.1038/nrm2312.
29. Lamkanfi M, Declercq W, Kalai M, Saelens X, Vandenabeele P. Alice in caspase land. A phylogenetic analysis of caspases from worm to man. Cell Death Differ. 2002;9(4):358-361, http://dx.doi.org/10.1038/sj.cdd.4400989.
30. Talanian RV, Quinlan C, Trautz S, Hackett MC, Mankovich JA, Banach D, et al. Substrate specificities of caspase family proteases. J Biol Chem. 1997;272(29):9677-9682.
31. Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem. 1997;272(29):17907-17911, http://dx.doi.org/10.1074/jbc.272.29.17907.
32. Guo Y, Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES. Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria. J Biol Chem. 2002;277(16):13430-13437, http://dx.doi.org/10.1074/jbc.M108029200.
33. Shen J, Vakifahmetoglu H, Stridh H, Zhivotovsky B, Wiman KG. PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2. Oncogene. 2008;27(51):6571-6580, http://dx.doi.org/10.1038/onc.2008.249.
34. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D. (1993) p21 is a universal inhibitor of cyclin kinases. Nature. 1993;366(6456):701-704, http://dx.doi.org/10.1038/366701a0.
35. Messina RL, Sanfilippo M, Vella V, Pandini G, Vigneri P, Nicolosi ML, et al. Reactivation of p53 mutants by p53 reactivation and induction of massive apoptosis in thyroid cancer cells. Int J Cancer. 2012;130(10):2259-2270.
36. Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer. 2002;2(9):647-656, http://dx.doi.org/10.1038/nrc883.
37. Watanabe FT, Chade DC, Reis ST, Piantino C, Dall'Oglio MF, Srougi M, Leite KR. Curcumin, but not Prima-1, decreased tumor cell proliferation in the syngeneic murine orthotopic bladder tumor model. Clinics. 2011;66(12):2121-2124, http://dx.doi.org/10.1590/S1807-59322011001200019.