Neuroprotection by steroids after neurotrauma in organotypic spinal cord cultures: A key role for progesterone receptors and steroidal modulators of GABAA receptors

Neuropharmacology

Volumn 71, Issue , 2013, Pages 46-55

  Labombarda, Florencia ^a,b   Ghoumari, Abdel Moumen ^a   Liere, Philippe ^a   De Nicola, Alejandro F ^b   Schumacher, Michael ^a   Guennoun, Rachida ^a  

^a Universite Paris Sud   (France)

^b INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

Author keywords

Allopregnanolone; GABAA receptors; Organotypic slice cultures; Progesterone; Progesterone receptor; Spinal cord

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 5ALPHA PREGNANE 3,20 DIONE; LACTATE DEHYDROGENASE; PROGESTERONE; PROGESTERONE RECEPTOR;

ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME RELEASE; GENETIC TRANSCRIPTION; HOMOZYGOTE; IN VITRO STUDY; KNOCKOUT MOUSE; MALE; MEMBRANE DAMAGE; MOTONEURON; MOUSE; NERVOUS SYSTEM INJURY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD;

5-ALPHA-DIHYDROPROGESTERONE; ANIMALS; CELL MEMBRANE; CELL NUCLEUS; CELL SURVIVAL; GABA-A RECEPTOR ANTAGONISTS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR NEURONS; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; PREGNANOLONE; PROGESTERONE; RECEPTORS, GABA-A; RECEPTORS, PROGESTERONE; SPINAL CORD; SPINAL CORD INJURIES; TISSUE CULTURE TECHNIQUES;

EID: 84878157300     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.03.010     Document Type: Article

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