Production of 5α-Reduced Neurosteroids Is Developmentally Regulated and Shapes GABAA Miniature IPSCs in Lamina II of the Spinal Cord

Journal of Neuroscience

Volumn 24, Issue 4, 2004, Pages 907-915

  Keller, A Florence ^a   Breton, Jean Didier ^a   Schlichter, Rémy ^a   Poisbeau, Pierrick ^a,b  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b CNRS   (France)

Author keywords

Allopregnanolone; Benzodiazepine; Cotransmission; Dorsal horn; GABA A; Inhibition; mIPSCs; Neurosteroidogenesis; Neurosteroids; Nociception; Pain; Substantia gelatinosa

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE RECEPTOR; BENZODIAZEPINE RECEPTOR BLOCKING AGENT; DIAZEPAM; FINASTERIDE; FLUMAZENIL; GLYCINE RECEPTOR; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NEUROSTEROID; STEROID 5ALPHA REDUCTASE; STEROID 5ALPHA REDUCTASE INHIBITOR; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; ELTANOLONE; ENZYME INHIBITOR; ISOQUINOLINE DERIVATIVE; STEROID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEGRADATION; IMMATURITY; INHIBITORY POSTSYNAPTIC POTENTIAL; INOTROPISM; KINETICS; NERVOUS SYSTEM DEVELOPMENT; NOCICEPTION; NONHUMAN; PAIN; PATCH CLAMP; PRIORITY JOURNAL; RAT; REDUCTION; SPINAL CORD DORSAL HORN; STEROIDOGENESIS; SUBSTANTIA GELATINOSA; SYNAPTIC TRANSMISSION; AGE; ANIMAL; CELL MEMBRANE POTENTIAL; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IN VITRO STUDY; METABOLISM; NERVE CELL INHIBITION; PHYSIOLOGY; POSTERIOR HORN CELL; SPINAL CORD; WISTAR RAT;

AGE FACTORS; ANIMALS; DIAZEPAM; ENZYME INHIBITORS; FINASTERIDE; GABA MODULATORS; ISOQUINOLINES; MEMBRANE POTENTIALS; NEURAL INHIBITION; PATCH-CLAMP TECHNIQUES; POSTERIOR HORN CELLS; PREGNANOLONE; RATS; RATS, WISTAR; RECEPTORS, GABA-A; RECEPTORS, GLYCINE; SPINAL CORD; STEROIDS; TESTOSTERONE 5-ALPHA-REDUCTASE;

EID: 0742287913     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4642-03.2004     Document Type: Article

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