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Volumn 1, Issue 4, 2001, Pages 382-386

Bilateral Pharmacokinetic Interaction between Cyclosporine A and Atorvastatin in Renal Transplant Recipients

Author keywords

Atorvastatin; Cyclosporine A; Interaction; Lipids; Pharmacokinetics; Renal transplantation

Indexed keywords

ATORVASTATIN; BASILIXIMAB; CYCLOSPORIN; DIAGNOSTIC AGENT; HEPTANOIC ACID DERIVATIVE; HYBRID PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY; PREDNISOLONE; PYRROLE DERIVATIVE;

EID: 0035502455     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-6143.2001.10415.x     Document Type: Article
Times cited : (121)

References (29)
  • 1
    • 0032971399 scopus 로고    scopus 로고
    • The role of lipid lowering in transplantation
    • Wierzbicki AS. The role of lipid lowering in transplantation. Int J Clin Pract 1999; 53: 54-59.
    • (1999) Int J Clin Pract , vol.53 , pp. 54-59
    • Wierzbicki, A.S.1
  • 3
    • 0033064071 scopus 로고    scopus 로고
    • Increase in cerivastatin systemic exposure after single and multiple dosing in cyclosporine-treated kidney transplant recipients
    • Mück W, Mai I, Fritsche L et al. Increase in cerivastatin systemic exposure after single and multiple dosing in cyclosporine-treated kidney transplant recipients. Clin Pharmacol Ther 1999; 65: 251-261.
    • (1999) Clin Pharmacol Ther , vol.65 , pp. 251-261
    • Mück, W.1    Mai, I.2    Fritsche, L.3
  • 4
    • 12644251055 scopus 로고    scopus 로고
    • Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses
    • Olbricht C, Wanner C, Eisenhauer T et al. Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses. Clin Pharmacol Ther 1997; 62: 311-321.
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 311-321
    • Olbricht, C.1    Wanner, C.2    Eisenhauer, T.3
  • 5
    • 0030463459 scopus 로고    scopus 로고
    • Evaluation of fluvastatin in the treatment of hypercholesterolemia in renal transplant recipients taking cyclosporine
    • Goldberg R, Roth D. Evaluation of fluvastatin in the treatment of hypercholesterolemia in renal transplant recipients taking cyclosporine. Transplantation 1996; 62: 1559-1564.
    • (1996) Transplantation , vol.62 , pp. 1559-1564
    • Goldberg, R.1    Roth, D.2
  • 6
    • 0028942815 scopus 로고
    • Efficacy and pharmacokinetics of simvastatin in heart transplant recipients
    • Campana C, Iacona I, Regazzi MB et al. Efficacy and pharmacokinetics of simvastatin in heart transplant recipients. Ann Pharmacother 1995; 29: 235-239.
    • (1995) Ann Pharmacother , vol.29 , pp. 235-239
    • Campana, C.1    Iacona, I.2    Regazzi, M.B.3
  • 7
    • 0031736655 scopus 로고    scopus 로고
    • Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: Are the statins mechanistically similar?
    • Christians U, Jacobsen W, Floren LC. Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar? Pharmacol Ther 1998; 80: 1-34.
    • (1998) Pharmacol Ther , vol.80 , pp. 1-34
    • Christians, U.1    Jacobsen, W.2    Floren, L.C.3
  • 8
    • 0030812885 scopus 로고    scopus 로고
    • In vitro metabolism of simvastatin in humans [SBT] identification of metabolizing enzymes and effect of the drug on hepatic P450s
    • Prueksaritanont T, Gorham LM, Ma B et al. In vitro metabolism of simvastatin in humans [SBT] identification of metabolizing enzymes and effect of the drug on hepatic P450s. Drug Metab Dispos 1997; 25: 1191-1199.
    • (1997) Drug Metab Dispos , vol.25 , pp. 1191-1199
    • Prueksaritanont, T.1    Gorham, L.M.2    Ma, B.3
  • 9
    • 0032212982 scopus 로고    scopus 로고
    • Atorvastatin: A hydroxymethylglutaryl-coenzyme A reductase inhibitor
    • quiz: 2302-2253
    • Malinowski JM. Atorvastatin: a hydroxymethylglutaryl-coenzyme A reductase inhibitor. Am J Health Syst Pharm 1998; 55: 2253-2267(quiz: 2302-2253).
    • (1998) Am J Health Syst Pharm , vol.55 , pp. 2253-2267
    • Malinowski, J.M.1
  • 10
    • 0031658907 scopus 로고    scopus 로고
    • Rational assessment of the interaction profile of cerivastatin supports its low propensity for drug interactions
    • Mück W. Rational assessment of the interaction profile of cerivastatin supports its low propensity for drug interactions. Drugs 1998; 56: 15-23.
    • (1998) Drugs , vol.56 , pp. 15-23
    • Mück, W.1
  • 11
    • 0032911163 scopus 로고    scopus 로고
    • Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver
    • Jacobsen W, Kirchner G, Hallensleben K et al. Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver. Drug Metab Dispos 1999; 27: 173-179.
    • (1999) Drug Metab Dispos , vol.27 , pp. 173-179
    • Jacobsen, W.1    Kirchner, G.2    Hallensleben, K.3
  • 12
    • 0032937343 scopus 로고    scopus 로고
    • The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: Effect on human cytochrome P-450 and implications for metabolic drug interactions
    • Fischer V, Johanson L, Heitz F et al. The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions. Drug Metab Dispos 1999; 27: 410-416.
    • (1999) Drug Metab Dispos , vol.27 , pp. 410-416
    • Fischer, V.1    Johanson, L.2    Heitz, F.3
  • 13
    • 0031669569 scopus 로고    scopus 로고
    • Delay of metabolism rate of ciclosporin by simvastatin in 7 Chinese healthy men
    • Xu F, Wu ZH, Zhang ZY, Zou HQ. Delay of metabolism rate of ciclosporin by simvastatin in 7 Chinese healthy men. Chung Kuo Yao Li Hsueh Pao 1998; 19: 443-444.
    • (1998) Chung Kuo Yao Li Hsueh Pao , vol.19 , pp. 443-444
    • Xu, F.1    Wu, Z.H.2    Zhang, Z.Y.3    Zou, H.Q.4
  • 14
    • 0027619903 scopus 로고
    • A prospective study on treatment of hypercholesterolemia with lovastatin in renal transplant patients receiving cyclosporine
    • Cheung AK, DeVault GA Jr, Gregory MC. A prospective study on treatment of hypercholesterolemia with lovastatin in renal transplant patients receiving cyclosporine. J Am Soc Nephrol 1993; 3: 1884-1891.
    • (1993) J Am Soc Nephrol , vol.3 , pp. 1884-1891
    • Cheung, A.K.1    DeVault Jr., G.A.2    Gregory, M.C.3
  • 15
    • 0024417537 scopus 로고
    • Lovastatin therapy for hypercholesterolemia in cardiac transplant recipients
    • Kuo PC, Kirshenbaum JM, Gordon J et al. Lovastatin therapy for hypercholesterolemia in cardiac transplant recipients. Am J Cardiol 1989; 64: 631-635.
    • (1989) Am J Cardiol , vol.64 , pp. 631-635
    • Kuo, P.C.1    Kirshenbaum, J.M.2    Gordon, J.3
  • 16
    • 0035165026 scopus 로고    scopus 로고
    • Efficacy and drug interactions of the new HMG-CoA reductase inhibitors cerivastatin and atorvastatin in CsA-treated renal transplant recipients
    • Renders L, Mayer-Kadner I, Koch C et al. Efficacy and drug interactions of the new HMG-CoA reductase inhibitors cerivastatin and atorvastatin in CsA-treated renal transplant recipients. Nephrol Dial Transplant 2001; 16: 141-146.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 141-146
    • Renders, L.1    Mayer-Kadner, I.2    Koch, C.3
  • 17
    • 6844260530 scopus 로고    scopus 로고
    • Post-transplant hyperlipidaemia: Low-dose lovastatin lowers atherogenic lipids without plasma accumulation of lovastatin
    • Gullestad L, Nordal KP, Forfang K et al. Post-transplant hyperlipidaemia: low-dose lovastatin lowers atherogenic lipids without plasma accumulation of lovastatin. J Intern Med 1997; 242: 483-490.
    • (1997) J Intern Med , vol.242 , pp. 483-490
    • Gullestad, L.1    Nordal, K.P.2    Forfang, K.3
  • 19
    • 0010919204 scopus 로고    scopus 로고
    • Cyclosporine and pravastatin pharmacokinetics in cardiac transplant recipients
    • Kobashigawa JA, Moriguchi JD, Sabad A et al. Cyclosporine and pravastatin pharmacokinetics in cardiac transplant recipients. J Heart Lung Transplant 1997; 16: 84.
    • (1997) J Heart Lung Transplant , vol.16 , pp. 84
    • Kobashigawa, J.A.1    Moriguchi, J.D.2    Sabad, A.3
  • 20
    • 0027377733 scopus 로고
    • Plasma concentration profiles of simvastatin 3-hydroxy-3-methyl- Glutaryl-coenzyme A reductase inhibitory activity in kidney transplant recipients with and without ciclosporin
    • Amadottir M, Eriksson LO, Thysell H, Karkas JD. Plasma concentration profiles of simvastatin 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitory activity in kidney transplant recipients with and without ciclosporin. Nephron 1993; 65: 410-413.
    • (1993) Nephron , vol.65 , pp. 410-413
    • Amadottir, M.1    Eriksson, L.O.2    Thysell, H.3    Karkas, J.D.4
  • 21
    • 0027327029 scopus 로고
    • Altered disposition of pravastatin following concomitant drug therapy with cyclosporin A in transplant recipients
    • Regazzi MB, Iacona I, Campana C et al. Altered disposition of pravastatin following concomitant drug therapy with cyclosporin A in transplant recipients. Transplant Proc 1993; 25: 2732-2734.
    • (1993) Transplant Proc , vol.25 , pp. 2732-2734
    • Regazzi, M.B.1    Iacona, I.2    Campana, C.3
  • 22
    • 0030870919 scopus 로고    scopus 로고
    • Renal dysfunction does not alter the pharmacokinetics or LDL-cholesterol reduction of atorvastatin
    • Stern RH, Yang BB, Horton M, Moore S, Abel RB, Olson SC. Renal dysfunction does not alter the pharmacokinetics or LDL-cholesterol reduction of atorvastatin. J Clin Pharmacol 1997; 37: 816-819.
    • (1997) J Clin Pharmacol , vol.37 , pp. 816-819
    • Stern, R.H.1    Yang, B.B.2    Horton, M.3    Moore, S.4    Abel, R.B.5    Olson, S.C.6
  • 23
    • 0027283631 scopus 로고
    • Cyclosporine a monitoring in patients with renal, cardiac, and liver transplants: A comparison between fluorescence polarization immunoassay and two different RIa methods
    • Bergan S, Rugstad HE, Stokke O, Bentdal O, Frøysaker T, Bergan A. Cyclosporine A monitoring in patients with renal, cardiac, and liver transplants: a comparison between fluorescence polarization immunoassay and two different RIA methods. Scand J Clin Lab Invest 1993; 53: 471-477.
    • (1993) Scand J Clin Lab Invest , vol.53 , pp. 471-477
    • Bergan, S.1    Rugstad, H.E.2    Stokke, O.3    Bentdal, O.4    Frøysaker, T.5    Bergan, A.6
  • 24
    • 0031886036 scopus 로고    scopus 로고
    • Development validation, and interlaboratory comparison of an HMG-CoA reductase inhibition assay for quantitation of atorvastatin in plasma matrices
    • Shum YY, Huang N, Walter G et al. Development validation, and interlaboratory comparison of an HMG-CoA reductase inhibition assay for quantitation of atorvastatin in plasma matrices. Ther Drug Monit 1998; 20: 41-49.
    • (1998) Ther Drug Monit , vol.20 , pp. 41-49
    • Shum, Y.Y.1    Huang, N.2    Walter, G.3
  • 25
    • 0025818108 scopus 로고
    • HMG-CoA reductase inhibitor-induced myopathy in the rat: Cyclosporine A interaction and mechanism studies
    • Smith PF, Eydelloth RS, Grossman SJ et al. HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies. J Pharmacol Exp Ther 1991; 257: 1225-1235.
    • (1991) J Pharmacol Exp Ther , vol.257 , pp. 1225-1235
    • Smith, P.F.1    Eydelloth, R.S.2    Grossman, S.J.3
  • 26
    • 0034059327 scopus 로고    scopus 로고
    • Atorvastatin transport in the Caco-2 cell model: Contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter
    • Wu X, Whitfield LR, Stewart BH. Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter. Pharm Res 2000; 17: 209-215.
    • (2000) Pharm Res , vol.17 , pp. 209-215
    • Wu, X.1    Whitfield, L.R.2    Stewart, B.H.3
  • 27
    • 0033678688 scopus 로고    scopus 로고
    • Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-grycoprotein-mediated secretion
    • Boyd RA, Stern RH, Stewart BH et al. Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-grycoprotein-mediated secretion. J Clin Pharmacol 2000; 40: 91-98.
    • (2000) J Clin Pharmacol , vol.40 , pp. 91-98
    • Boyd, R.A.1    Stern, R.H.2    Stewart, B.H.3
  • 28
    • 0033601257 scopus 로고    scopus 로고
    • A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
    • Hsiang B, Zhu Y, Wang Z et al. A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J Biol Chem 1999; 274: 37161-37168.
    • (1999) J Biol Chem , vol.274 , pp. 37161-37168
    • Hsiang, B.1    Zhu, Y.2    Wang, Z.3
  • 29
    • 0343416856 scopus 로고    scopus 로고
    • Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery
    • Hebert MF. Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery. Adv Drug Deliv Rev 1997; 27: 201-214.
    • (1997) Adv Drug Deliv Rev , vol.27 , pp. 201-214
    • Hebert, M.F.1


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