-
1
-
-
0015239444
-
Modulation of the kinetic properties of phosphofructokinase by ammonium ions
-
4251852 1:STN:280:DyaE3M7mtlKntg%3D%3D
-
Abrahams SL, Younathan ES (1971) Modulation of the kinetic properties of phosphofructokinase by ammonium ions. J Biol Chem 246(8):2464-2467
-
(1971)
J Biol Chem
, vol.246
, Issue.8
, pp. 2464-2467
-
-
Abrahams, S.L.1
Younathan, E.S.2
-
2
-
-
77950644610
-
Metabolic alterations induced by ischemia in primary cultures of astrocytes: Merging 13C NMR spectroscopy and metabolic flux analysis
-
20141568 10.1111/j.1471-4159.2010.06636.x 1:CAS:528:DC%2BC3cXls1amtbk%3D
-
Amaral AI, Teixeira AP, Martens S, Bernal V, Sousa MF, Alves PM (2010) Metabolic alterations induced by ischemia in primary cultures of astrocytes: merging 13C NMR spectroscopy and metabolic flux analysis. J Neurochem 113(3):735-748
-
(2010)
J Neurochem
, vol.113
, Issue.3
, pp. 735-748
-
-
Amaral, A.I.1
Teixeira, A.P.2
Martens, S.3
Bernal, V.4
Sousa, M.F.5
Alves, P.M.6
-
3
-
-
33745893228
-
The glutamate/GABA-glutamine cycle: Aspects of transport, neurotransmitter homeostasis and ammonia transfer
-
16787421 10.1111/j.1471-4159.2006.03913.x 1:CAS:528:DC%2BD28XovFGhsL4%3D
-
Bak LK, Schousboe A, Waagepetersen HS (2006) The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer. J Neurochem 98:641-653
-
(2006)
J Neurochem
, vol.98
, pp. 641-653
-
-
Bak, L.K.1
Schousboe, A.2
Waagepetersen, H.S.3
-
4
-
-
35848958365
-
Among the branched-chain amino acids only valine metabolism is up-regulated in astrocytes during glutamate exposure
-
10.1002/jnr.21347
-
Bak LK, Johansen ML, Schousboe A, Waagepetersen HS (2007) Among the branched-chain amino acids only valine metabolism is up-regulated in astrocytes during glutamate exposure. J Neurosci Res 86:3465-3470
-
(2007)
J Neurosci Res
, vol.86
, pp. 3465-3470
-
-
Bak, L.K.1
Johansen, M.L.2
Schousboe, A.3
Waagepetersen, H.S.4
-
5
-
-
60449106310
-
Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia
-
19067142 10.1007/s11011-008-9123-4 1:CAS:528:DC%2BD1MXhvVOjsrY%3D
-
Bak LK, Iversen P, Sørensen M, Keiding S, Vilstrup H, Ott P, Waagepetersen HS, Schousboe A (2009) Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia. Metab Brain Dis 24:135-145
-
(2009)
Metab Brain Dis
, vol.24
, pp. 135-145
-
-
Bak, L.K.1
Iversen, P.2
Sørensen, M.3
Keiding, S.4
Vilstrup, H.5
Ott, P.6
Waagepetersen, H.S.7
Schousboe, A.8
-
6
-
-
0014336644
-
Metabolism of [14C]leucine and [14C]acetate in sensorimotor cortex, thalamus, caudate nucleus and cerebellum of the cat
-
5682513 10.1111/j.1471-4159.1968.tb11639.x 1:CAS:528:DyaF1cXks1Gmurk%3D
-
Berl S, Frigyesi TL (1968) Metabolism of [14C]leucine and [14C]acetate in sensorimotor cortex, thalamus, caudate nucleus and cerebellum of the cat. J Neurochem 15(9):965-970
-
(1968)
J Neurochem
, vol.15
, Issue.9
, pp. 965-970
-
-
Berl, S.1
Frigyesi, T.L.2
-
7
-
-
0014485970
-
Comparison of cerebral regional metabolism of [14C]leucine following third ventricle and intravenous administration in the cat
-
5795592 10.1111/j.1471-4159.1969.tb10381.x 1:CAS:528:DyaF1MXpsVKitA%3D%3D
-
Berl S, Frigyesi TL (1969) Comparison of cerebral regional metabolism of [14C]leucine following third ventricle and intravenous administration in the cat. J Neurochem 16(3):405-415
-
(1969)
J Neurochem
, vol.16
, Issue.3
, pp. 405-415
-
-
Berl, S.1
Frigyesi, T.L.2
-
8
-
-
76249122306
-
Dietarybranched chain amino acids ameliorate injury-induced cognitive impairment
-
19995960 10.1073/pnas.0910280107 1:CAS:528:DC%2BC3cXnsFCrtQ%3D%3D
-
Cole JT, Mitala CM, Kundu S, Verma A, Elkind JA, Nissim I, Cohen AS (2010) Dietarybranched chain amino acids ameliorate injury-induced cognitive impairment. Proc Natl Acad Sci U S A 107(1):366-371
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.1
, pp. 366-371
-
-
Cole, J.T.1
Mitala, C.M.2
Kundu, S.3
Verma, A.4
Elkind, J.A.5
Nissim, I.6
Cohen, A.S.7
-
9
-
-
80052263625
-
13 N as a tracer for studying glutamate metabolism
-
21108979 10.1016/j.neuint.2010.11.011 1:CAS:528:DC%2BC3MXhtV2nurrI
-
13 N as a tracer for studying glutamate metabolism. Neurochem Int 59(4):456-464
-
(2011)
Neurochem Int
, vol.59
, Issue.4
, pp. 456-464
-
-
Cooper, A.J.1
-
10
-
-
79955646990
-
Inhibition of glutamine synthetase induces glutamate dehydrogenase- dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons
-
21397649 10.1016/j.neuint.2011.03.008 1:CAS:528:DC%2BC3MXhtV2nurrL
-
Dadsetan S, Bak LK, Sørensen M, Keiding S, Vilstrup H, Ott P, Leke R, Schousboe A, Waagepetersen HS (2011) Inhibition of glutamine synthetase induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons. Neurochem Int 59:482-488
-
(2011)
Neurochem Int
, vol.59
, pp. 482-488
-
-
Dadsetan, S.1
Bak, L.K.2
Sørensen, M.3
Keiding, S.4
Vilstrup, H.5
Ott, P.6
Leke, R.7
Schousboe, A.8
Waagepetersen, H.S.9
-
11
-
-
84871712725
-
Interorgan metabolism of ornithine phenylacetate - A novel strategy for treatment of hyperammonimia
-
Dadsetan S, Sørensen M, Bak LK, Vilstrup H, Ott P, Schousboe A, Jalan R, Keiding S, Waagepetersen HS (2013) Interorgan metabolism of ornithine phenylacetate - A novel strategy for treatment of hyperammonimia. Biochem Pharmacol 85:115-123
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 115-123
-
-
Dadsetan S, S.1
-
12
-
-
79961017249
-
Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic ammonia metabolism in patients with cirrhosis and healthy subjects
-
10.1152/ajpgi.00062.2011 1:CAS:528:DC%2BC3MXhtFSqurbF
-
Dam G, Keiding S, Ol M, Ott P, Buhl M, Vilstrup H, Bak LK, Waagepetersen HS, Schousboe A, Møller N, Sørensen M (2011) Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic ammonia metabolism in patients with cirrhosis and healthy subjects. Am J Gastrointest Liver Physiol 301:G269-G277
-
(2011)
Am J Gastrointest Liver Physiol
, vol.301
-
-
Dam, G.1
Keiding, S.2
Ol, M.3
Ott, P.4
Buhl, M.5
Vilstrup, H.6
Bak, L.K.7
Waagepetersen, H.S.8
Schousboe, A.9
Møller, N.10
Sørensen, M.11
-
13
-
-
0015962433
-
Plasma amino acids in patients with hepatic encephalopathy. Effects of amino acid infusions
-
4808685 10.1016/0002-9610(74)90009-9 1:STN:280:DyaE2c%2Flt1yhsA%3D%3D
-
Fischer JE, Yoshimura N, Aguirre A, James JH, Cummings MG, Abel RM, Deindoerfer F (1974) Plasma amino acids in patients with hepatic encephalopathy. Effects of amino acid infusions. Am J Surg 127(1):40-47
-
(1974)
Am J Surg
, vol.127
, Issue.1
, pp. 40-47
-
-
Fischer, J.E.1
Yoshimura, N.2
Aguirre, A.3
James, J.H.4
Cummings, M.G.5
Abel, R.M.6
Deindoerfer, F.7
-
14
-
-
0017954946
-
Cerebral blood flow and metabolism in chronically hyperammonemic rats: Effect of an acute ammonia challenge
-
666274 10.1002/ana.410030409 1:CAS:528:DyaE1cXksVSgt7o%3D
-
Gjedde A, Lockwood AH, Duffy TE, Plum F (1978) Cerebral blood flow and metabolism in chronically hyperammonemic rats: effect of an acute ammonia challenge. Ann Neurol 3:325-330
-
(1978)
Ann Neurol
, vol.3
, pp. 325-330
-
-
Gjedde, A.1
Lockwood, A.H.2
Duffy, T.E.3
Plum, F.4
-
15
-
-
0034257070
-
Neuronal-astrocytic and cytosolic-mitochondrial metabolite trafficking during brain activation, hyperammonemia and energy deprivation
-
10812194 10.1016/S0197-0186(00)00012-7 1:CAS:528:DC%2BD3cXksF2gsbw%3D
-
Hertz L, Yu ACH, Kala G, Schousboe A (2000) Neuronal-astrocytic and cytosolic-mitochondrial metabolite trafficking during brain activation, hyperammonemia and energy deprivation. Neurochem Int 37:83-102
-
(2000)
Neurochem Int
, vol.37
, pp. 83-102
-
-
Hertz, L.1
Yu, A.C.H.2
Kala, G.3
Schousboe, A.4
-
16
-
-
0017362424
-
Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts
-
838855 10.1172/JCI108651 1:CAS:528:DyaE2sXhs1yqu70%3D
-
Hindfelt B, Plum F, Duffy TE (1977) Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts. J Clin Invest 59:386-396
-
(1977)
J Clin Invest
, vol.59
, pp. 386-396
-
-
Hindfelt, B.1
Plum, F.2
Duffy, T.E.3
-
17
-
-
80052260152
-
Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: Intersecting metabolic pathways
-
21621574 10.1016/j.neuint.2011.05.001 1:CAS:528:DC%2BC3MXhtV2nurvN
-
Hutson SM, Islam MM, Zaganas I (2011) Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways. Neurochem Int 59(4):518-524
-
(2011)
Neurochem Int
, vol.59
, Issue.4
, pp. 518-524
-
-
Hutson, S.M.1
Islam, M.M.2
Zaganas, I.3
-
18
-
-
73649126526
-
Branched-chain amino acid metabolon: Interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm)
-
19858196 10.1074/jbc.M109.048777 1:CAS:528:DC%2BD1MXhs1SqsbbE
-
Islam MM, Nautiyal M, Wynn RM, Mobley JA, Chuang DT, Hutson SM (2010) Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm). J Biol Chem 285(1):265-276
-
(2010)
J Biol Chem
, vol.285
, Issue.1
, pp. 265-276
-
-
Islam, M.M.1
Nautiyal, M.2
Wynn, R.M.3
Mobley, J.A.4
Chuang, D.T.5
Hutson, S.M.6
-
19
-
-
34249699637
-
A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex
-
17314104 10.1074/jbc.M700198200 1:CAS:528:DC%2BD2sXktFelsrc%3D
-
Islam MM, Wallin R, Wynn RM, Conway M, Fujii H, Mobley JA, Chuang DT, Hutson SM (2007) A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex. J Biol Chem 282(16):11893-11903
-
(2007)
J Biol Chem
, vol.282
, Issue.16
, pp. 11893-11903
-
-
Islam, M.M.1
Wallin, R.2
Wynn, R.M.3
Conway, M.4
Fujii, H.5
Mobley, J.A.6
Chuang, D.T.7
Hutson, S.M.8
-
20
-
-
34548737013
-
L-Ornithine phenylacetate (OP): A novel treatment for hyperammonemia and hepatic encephalopathy
-
17467190 10.1016/j.mehy.2006.12.061 1:CAS:528:DC%2BD2sXhtVOgs73N
-
Jalan R, Wright G, Davies NV, Hodges SJ (2007) L-Ornithine phenylacetate (OP): a novel treatment for hyperammonemia and hepatic encephalopathy. Med Hypotheses 69:1064-1069
-
(2007)
Med Hypotheses
, vol.69
, pp. 1064-1069
-
-
Jalan, R.1
Wright, G.2
Davies, N.V.3
Hodges, S.J.4
-
21
-
-
34250718524
-
The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes
-
17346854 10.1016/j.neuint.2007.01.009 1:CAS:528:DC%2BD2sXmvVKms70%3D
-
Johansen ML, Bak LK, Schousboe A, Iversen P, Sørensen M, Keiding S, Vilstrup H, Gjedde A, Ott P, Waagepetersen HS (2007) The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes. Neurochem Int 50:1042-1051
-
(2007)
Neurochem Int
, vol.50
, pp. 1042-1051
-
-
Johansen, M.L.1
Bak, L.K.2
Schousboe, A.3
Iversen, P.4
Sørensen, M.5
Keiding, S.6
Vilstrup, H.7
Gjedde, A.8
Ott, P.9
Waagepetersen, H.S.10
-
22
-
-
20544452196
-
Ammonia effects on pyruvate/lactate production in astrocytes-Interaction with glutamate
-
15890434 10.1016/j.neuint.2005.04.001 1:CAS:528:DC%2BD2MXlsl2ktLs%3D
-
Kala G, Hertz L (2005) Ammonia effects on pyruvate/lactate production in astrocytes-Interaction with glutamate. Neurochem Int 47:4-12
-
(2005)
Neurochem Int
, vol.47
, pp. 4-12
-
-
Kala, G.1
Hertz, L.2
-
23
-
-
0022972426
-
Brain alpha-ketogkutarate dehydrogenase complex: Kinetic properties, regional distribution, and effects of inhibitors
-
10.1111/j.1471-4159.1986.tb00768.x
-
Laj JC, Cooper AJ (1986) Brain alpha-ketogkutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors. J Neurochem 47:1376-1386
-
(1986)
J Neurochem
, vol.47
, pp. 1376-1386
-
-
Laj, J.C.1
Cooper, A.J.2
-
24
-
-
79951948409
-
Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine
-
20480276 10.1007/s12640-010-9198-7 1:CAS:528:DC%2BC3MXltVGrsb0%3D
-
Leke R, Bak LK, Anker M, Melø TM, Sørensen M, Keiding S, Vilstrup H, Ott P, Portela LV, Sonnewald U, Schousboe A, Waagepetersen HS (2011) Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine. Neurotox Res 19:496-510
-
(2011)
Neurotox Res
, vol.19
, pp. 496-510
-
-
Leke, R.1
Bak, L.K.2
Anker, M.3
Melø, T.M.4
Sørensen, M.5
Keiding, S.6
Vilstrup, H.7
Ott, P.8
Portela, L.V.9
Sonnewald, U.10
Schousboe, A.11
Waagepetersen, H.S.12
-
25
-
-
0035100128
-
Nitrogen shuttling between neurons and glial cells during glutamate synthesis
-
11259489 10.1046/j.1471-4159.2001.00156.x 1:CAS:528:DC%2BD3MXitlSktrs%3D
-
Lieth E, LaNoue KF, Berkich DA, Xu B, Ratz M, Taylor C, Hutson SM (2001) Nitrogen shuttling between neurons and glial cells during glutamate synthesis. J Neurochem 76:1712-1723
-
(2001)
J Neurochem
, vol.76
, pp. 1712-1723
-
-
Lieth, E.1
Lanoue, K.F.2
Berkich, D.A.3
Xu, B.4
Ratz, M.5
Taylor, C.6
Hutson, S.M.7
-
26
-
-
0000187648
-
Ammonia toxicity and cerebral oxidative metabolism
-
13774048 1:CAS:528:DyaF3MXns1GjsA%3D%3D
-
McKhann GM, Tower DB (1961) Ammonia toxicity and cerebral oxidative metabolism. Am J Physiol 200:420-424
-
(1961)
Am J Physiol
, vol.200
, pp. 420-424
-
-
McKhann, G.M.1
Tower, D.B.2
-
27
-
-
77049278926
-
Über den aminosäurenhaushalt bei leberkrankheiten
-
10.1055/s-0028-1115247
-
Müting D, Wortmann V (1956) Über den aminosäurenhaushalt bei leberkrankheiten. Deutsche Medizinische Wochenschrift 45:1853-1856
-
(1956)
Deutsche Medizinische Wochenschrift
, vol.45
, pp. 1853-1856
-
-
Müting, D.1
Wortmann, V.2
-
28
-
-
84860570399
-
2+ homeostasis and metabolism of glucose in astrocytes with emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: Implications for glutamate neurotransmission and excitotoxicity
-
22194159 10.1007/s12640-011-9296-1 1:CAS:528:DC%2BC38Xjs1Clt7w%3D
-
2+ homeostasis and metabolism of glucose in astrocytes with emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: Implications for glutamate neurotransmission and excitotoxicity. Neurotox Res 21:405-417
-
(2012)
Neurotox Res
, vol.21
, pp. 405-417
-
-
Obel, L.F.1
Andersen, K.M.H.2
Bak, L.K.3
Schousboe, A.4
Waagepetersen, H.S.5
-
29
-
-
0036093026
-
Interorgan ammonia metabolism in liver failure
-
12020618 10.1016/S0197-0186(02)00040-2 1:CAS:528:DC%2BD38XjvVejtbk%3D
-
Olde Damink SW, Deutz NE, Dejong CH, Soeters PB, Jalan R (2002) Interorgan ammonia metabolism in liver failure. Neurochem Int 41(2-3):177-188
-
(2002)
Neurochem Int
, vol.41
, Issue.2-3
, pp. 177-188
-
-
Olde Damink, S.W.1
Deutz, N.E.2
Dejong, C.H.3
Soeters, P.B.4
Jalan, R.5
-
30
-
-
20544451967
-
Cerebral metabolic disturbances in the brain during acute liver failure: From hyperammonemia to energy failure and proteolysis
-
15921824 10.1016/j.neuint.2005.04.002 1:CAS:528:DC%2BD2MXlsl2kt7k%3D
-
Ott P, Clemmesen O, Larsen FS (2005) Cerebral metabolic disturbances in the brain during acute liver failure: From hyperammonemia to energy failure and proteolysis. Neurochem Int 47:13-18
-
(2005)
Neurochem Int
, vol.47
, pp. 13-18
-
-
Ott, P.1
Clemmesen, O.2
Larsen, F.S.3
-
31
-
-
79955961530
-
Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo
-
21575862 10.1016/j.ccr.2011.03.012 1:CAS:528:DC%2BC3MXmtFGls7g%3D
-
Sheen JH, Zoncu R, Kim D, Sabatini DM (2011) Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo. Cancer Cell 19(5):613-628
-
(2011)
Cancer Cell
, vol.19
, Issue.5
, pp. 613-628
-
-
Sheen, J.H.1
Zoncu, R.2
Kim, D.3
Sabatini, D.M.4
-
32
-
-
0021348708
-
14C-labeled glutamate in astrocytes in primary cultures
-
6141224 10.1111/j.1471-4159.1984.tb02721.x 1:CAS:528:DyaL2cXpslyitA%3D%3D
-
14C-labeled glutamate in astrocytes in primary cultures. J Neurochem 42:594-597
-
(1984)
J Neurochem
, vol.42
, pp. 594-597
-
-
Yu, A.C.H.1
Schousboe, A.2
Hertz, L.3
-
33
-
-
0031239010
-
Brain metabolism of branched-chain amino acids
-
9298851 10.1002/(SICI)1098-1136(199709)21:1<92: AID-GLIA10>3.0. CO;2-W 1:STN:280:DyaK2svkt1ejsA%3D%3D
-
Yudkoff M (1997) Brain metabolism of branched-chain amino acids. Glia 21(1):92-98
-
(1997)
Glia
, vol.21
, Issue.1
, pp. 92-98
-
-
Yudkoff, M.1
-
34
-
-
0033673044
-
13C]alanine in astrocytes, neurons, and cocultures. Implications for neuron-glia interactions in neurotransmitter metabolism
-
10.1002/1098-1136(200012)32:3<286: AID-GLIA80>3.0.CO;2-P
-
13C]alanine in astrocytes, neurons, and cocultures. Implications for neuron-glia interactions in neurotransmitter metabolism. Glia 32:386-303
-
(2000)
Glia
, vol.32
, pp. 386-303
-
-
Zwingmann, C.1
Richter-Landsberg, C.2
Brand, A.3
Leibfritz, D.4
-
35
-
-
0037311146
-
Selective increase of brain lactate synthesis in experimental acute liver failure. Results of a [H-C] nuclear magnetic resonance study
-
12540793 10.1053/jhep.2003.50052 1:CAS:528:DC%2BD3sXhsFeltrs%3D
-
Zwingmann C, Chatauret N, Leibfritz D, Butterworth RF (2003) Selective increase of brain lactate synthesis in experimental acute liver failure. Results of a [H-C] nuclear magnetic resonance study. Hepatology 37:420-428
-
(2003)
Hepatology
, vol.37
, pp. 420-428
-
-
Zwingmann, C.1
Chatauret, N.2
Leibfritz, D.3
Butterworth, R.F.4
-
36
-
-
0033929168
-
A possible role of alanine for ammonia transfer between astrocytes and glutamatergic neurons
-
Waagepetersen HS, Sonnewald U, Larsson OM, Schousboe A (2000) A possible role of alanine for ammonia transfer between astrocytes and glutamatergic neurons. J Neurochem 75(2):471-9
-
(2000)
J Neurochem
, vol.75
, Issue.2
, pp. 471-479
-
-
Waagepetersen, H.S.1
Sonnewald, U.2
Larsson, O.M.3
Schousboe, A.4
|