-
1
-
-
0027408080
-
Free radicals as mediators of tissue injury and disease
-
J.P. Kehrer Free radicals as mediators of tissue injury and disease Crit. Rev. Toxicol. 23 1993 21 48 (Pubitemid 23094393)
-
(1993)
Critical Reviews in Toxicology
, vol.23
, Issue.1
, pp. 21-48
-
-
Kehrer, J.P.1
-
2
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
T. Finkel, and N.J. Holbrook Oxidants, oxidative stress and the biology of ageing Nature 408 2000 239 247
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
3
-
-
0029133790
-
Cellular injury induced by oxidative stress is mediated through lysosomal damage
-
K. Ollinger, and U.T. Brunk Cellular injury induced by oxidative stress is mediated through lysosomal damage Free Radic. Biol. Med. 19 1995 565 574
-
(1995)
Free Radic. Biol. Med.
, vol.19
, pp. 565-574
-
-
Ollinger, K.1
Brunk, U.T.2
-
4
-
-
0031670727
-
Nuclear ferritin protects DNA from UV damage in corneal epithelial cells
-
C.X. Cai, D.E. Birk, and T.F. Linsenmayer Nuclear ferritin protects DNA from UV damage in corneal epithelial cells Mol. Biol. Cell 9 1998 1037 1051 (Pubitemid 28457298)
-
(1998)
Molecular Biology of the Cell
, vol.9
, Issue.5
, pp. 1037-1051
-
-
Cai, C.X.1
Birk, D.E.2
Linsenmayer, T.F.3
-
5
-
-
0030296240
-
Subthreshold UV radiation-induced peroxide formation in cultured corneal epithelial cells: The protective effects of lactoferrin
-
DOI 10.1006/exer.1996.0142
-
S. Shimmura, M. Suematsu, M. Shimoyama, K. Tsubota, Y. Oguchi, Y. Ishimura, and UV Subthreshold radiation-induced peroxide formation in cultured corneal epithelial cells: the protective effects of lactoferrin Exp. Eye Res. 63 1996 519 526 (Pubitemid 26420793)
-
(1996)
Experimental Eye Research
, vol.63
, Issue.5
, pp. 519-526
-
-
Shimmura, S.1
Suematsu, M.2
Shimoyama, M.3
Tsubota, K.4
Oguchi, Y.5
Ishimura, Y.6
-
6
-
-
0036182862
-
Evidence of oxidative stress in human corneal diseases
-
R. Buddi, B. Lin, S.R. Atilano, N.C. Zorapapel, M.C. Kenney, and D.J. Brown Evidence of oxidative stress in human corneal diseases J. Histochem. Cytochem. 50 2002 341 351 (Pubitemid 34173022)
-
(2002)
Journal of Histochemistry and Cytochemistry
, vol.50
, Issue.3
, pp. 341-351
-
-
Buddi, R.1
Lin, B.2
Atilano, S.R.3
Zorapapel, N.C.4
Kenney, M.C.5
Brown, D.J.6
-
7
-
-
34248355963
-
Involvement of oxidative stress on corneal epithelial alterations in a blink-suppressed dry eye
-
DOI 10.1167/iovs.06-1027
-
S. Nakamura, M. Shibuya, H. Nakashima, R. Hisamura, N. Masuda, T. Imagawa, M. Uehara, and K. Tsubota Involvement of oxidative stress on corneal epithelial alterations in a blink-suppressed dry eye Invest. Ophthalmol. Visual Sci. 48 2007 1552 1558 (Pubitemid 351261338)
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, Issue.4
, pp. 1552-1558
-
-
Nakamura, S.1
Shibuya, M.2
Nakashima, H.3
Hisamura, R.4
Masuda, N.5
Imagawa, T.6
Uehara, M.7
Tsubota, K.8
-
9
-
-
0029411321
-
Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: Regulation by upstream antioxidant-responsive elements (ARE)
-
T. Prestera, P. Talalay, J. Alam, Y.I. Ahn, P.J. Lee, and A.M. Choi Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE) Mol. Med. 1 1995 827 837 (Pubitemid 3013090)
-
(1995)
Molecular Medicine
, vol.1
, Issue.7
, pp. 827-837
-
-
Prestera, T.1
Talalay, P.2
Alam, J.3
Ahn, Y.I.4
Lee, P.J.5
Choi, A.M.6
-
10
-
-
3142570440
-
The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress
-
DOI 10.1016/j.freeradbiomed.2004.04.033, PII S089158490400379X
-
T. Nguyen, C.S. Yang, and C.B. Pickett The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress Free Radic. Biol. Med. 37 2004 433 441 (Pubitemid 38901076)
-
(2004)
Free Radical Biology and Medicine
, vol.37
, Issue.4
, pp. 433-441
-
-
Nguyen, T.1
Yang, C.S.2
Pickett, C.B.3
-
11
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
K. Itoh, N. Wakabayashi, Y. Katoh, T. Ishii, K. Igarashi, J.D. Engel, and M. Yamamoto Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain Genes Dev. 13 1999 76 86 (Pubitemid 29045117)
-
(1999)
Genes and Development
, vol.13
, Issue.1
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
12
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
DOI 10.1006/bbrc.1997.6943
-
K. Itoh, T. Chiba, S. Takahashi, T. Ishii, K. Igarashi, Y. Katoh, T. Oyake, N. Hayashi, K. Satoh, I. Hatayama, M. Yamamoto, and Y. Nabeshima An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements Biochem. Biophys. Res. Commun. 236 1997 313 322 (Pubitemid 27373291)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.236
, Issue.2
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.-I.12
-
13
-
-
0025948113
-
The antioxidant responsive element: Activation by oxidative stress and identification of the dna consensus sequence required for functional activity
-
T.H. Rushmore, M.R. Morton, and C.B. Pickett The antioxidant responsive element: activation by oxidative stress and identification of the DNA consensus sequence required for functional activity J. Biol. Chem. 266 1991 11632 11639 (Pubitemid 21906996)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.18
, pp. 11632-11639
-
-
Rushmore, T.H.1
Morton, M.R.2
Pickett, C.B.3
-
14
-
-
0036318224
-
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound
-
DOI 10.1128/MCB.22.15.5492-5505.2002
-
S. Braun, C. Hanselmann, M.G. Gassmann, U. auf dem Keller, C. Born-Berclaz, K. Chan, Y.W. Kan, and S. Werner Nrf2 transcription factor, a novel target of keratinocytes growth factor action which regulates gene expression and inflammation in the healing skin wound Mol. Cell. Biol. 22 2002 5492 5505 (Pubitemid 34755759)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.15
, pp. 5492-5505
-
-
Braun, S.1
Hanselmann, C.2
Gassmann, M.G.3
Auf Dem Keller, U.A.4
Born-Berclaz, C.5
Chan, K.6
Kan, Y.W.7
Werner, S.8
-
15
-
-
33646561819
-
Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing
-
DOI 10.1128/MCB.26.10.3773-3784.2006
-
U. auf dem Keller, M. Huber, T.A. Beyer, A. Kümin, C. Siemes, S. Braun, P. Bugnon, V. Mitropoulos, D.A. Johnson, J.A. Johnson, D. Hohl, and S. Werner Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing Mol. Cell. Biol. 26 2006 3773 3784 (Pubitemid 43726395)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.10
, pp. 3773-3784
-
-
Auf Dem Keller, U.1
Huber, M.2
Beyer, T.A.3
Kumin, A.4
Siemes, C.5
Braun, S.6
Bugnon, P.7
Mitropoulos, V.8
Johnson, D.A.9
Johnson, J.A.10
Hohl, D.11
Werner, S.12
-
16
-
-
34250767177
-
Roles and mechanisms of action of the Nrf2 transcription factor in skin morphogenesis, wound repair and skin cancer
-
DOI 10.1038/sj.cdd.4402133, PII 4402133
-
T.A. Beyer, U. auf dem Keller, S. Braun, M. Schäfer, and S. Werner Roles and mechanisms of action of the Nrf2 transcription factor in skin morphogenesis, wound repair and skin cancer Cell Death Differ 14 2007 1250 1254 (Pubitemid 46965255)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.7
, pp. 1250-1254
-
-
Beyer, T.A.1
Auf Dem Keller, U.2
Braun, S.3
Schafer, M.4
Werner, S.5
-
17
-
-
0018729564
-
A simple method for the removal of rabbit corneal epithelium utilizing n-heptanol
-
C. Cintron, L. Hassinger, C.L. Kublin, and J. Friend A simple method for the removal of rabbit corneal epithelium utilizing n-heptanol Ophthalmic Res. 11 1979 90 96 (Pubitemid 10235400)
-
(1979)
Ophthalmic Research
, vol.11
, Issue.2
, pp. 90-96
-
-
Cintron, C.1
Hassinger, L.2
Kublin, C.L.3
Friend, J.4
-
18
-
-
79953703149
-
Cell migration and invasion assays as tools for drug discovery
-
K.I. Hulkower, and L.H. Renee Cell migration and invasion assays as tools for drug discovery Pharmaceutics 3 2011 107 124
-
(2011)
Pharmaceutics
, vol.3
, pp. 107-124
-
-
Hulkower, K.I.1
Renee, L.H.2
-
19
-
-
68249138311
-
Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas
-
e600-611
-
C. Rydberg, A. Månsson, R. Uddman, K. Riesbeck, and L.O. Cardell Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas. Immunology e600-611 2009
-
(2009)
Immunology
-
-
Rydberg, C.1
Månsson, A.2
Uddman, R.3
Riesbeck, K.4
Cardell, L.O.5
-
20
-
-
0037370196
-
Cell-matrix and cell-cell interactions during corneal epithelial wound healing
-
DOI 10.1016/S1350-9462(02)00042-3, PII S1350946202000423
-
K. Suzuki, J. Saito, R. Yanai, N. Yamada, T. Chikama, K. Seki, and T. Nishida Cell-matrix and cell-cell interactions during corneal epithelial wound healing. Prog. Retinal Eye Res 22 2003 113 133 (Pubitemid 36246530)
-
(2003)
Progress in Retinal and Eye Research
, vol.22
, Issue.2
, pp. 113-133
-
-
Suzuki, K.1
Saito, J.2
Yanai, R.3
Yamada, N.4
Chikama, T.-I.5
Seki, K.6
Nishida, T.7
-
21
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
DOI 10.1038/ng1248
-
N. Wakabayashi, K. Itoh, J. Wakabayashi, H. Motohashi, S. Noda, S. Takahashi, S. Imakado, T. Kotsuji, F. Otsuka, DR. Roop, T. Harada, J.D. Engel, and M. Yamamoto Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation Nat. Genet. 35 2003 238 245 (Pubitemid 37363177)
-
(2003)
Nature Genetics
, vol.35
, Issue.3
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
Imakado, S.7
Kotsuji, T.8
Otsuka, F.9
Roop, D.R.10
Harada, T.11
Engel, J.D.12
Yamamoto, M.13
-
22
-
-
77956640097
-
Regulation of notch1 signaling by nrf2: Implications for tissue regeneration
-
N. Wakabayashi, S. Shin, S.L. Slocum, E.S. Agoston, J. Wakabayashi, M.K. Kwak, V. Misra, S. Biswal, M. Yamamoto, and T.W. Kensler Regulation of notch1 signaling by nrf2: implications for tissue regeneration. Sci. Signaling 3 ra52 2010
-
(2010)
Sci. Signaling
, vol.3
, Issue.RA52
-
-
Wakabayashi, N.1
Shin, S.2
Slocum, S.L.3
Agoston, E.S.4
Wakabayashi, J.5
Kwak, M.K.6
Misra, V.7
Biswal, S.8
Yamamoto, M.9
Kensler, T.W.10
-
23
-
-
34547477930
-
Corneal Epithelial Cell Fate Is Maintained during Repair by Notch1 Signaling via the Regulation of Vitamin A Metabolism
-
DOI 10.1016/j.devcel.2007.06.012, PII S1534580707002614
-
S. Vauclair, F. Majo, A.D. Durham, N.B. Ghyselinck, Y. Barrandon, and F. Radtke Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism Dev. Cell 13 2007 242 253 (Pubitemid 47163608)
-
(2007)
Developmental Cell
, vol.13
, Issue.2
, pp. 242-253
-
-
Vauclair, S.1
Majo, F.2
Durham, A.-D.3
Ghyselinck, N.B.4
Barrandon, Y.5
Radtke, F.6
-
24
-
-
34648846569
-
A role for notch signaling in human corneal epithelial cell differentiation and proliferation
-
DOI 10.1167/iovs.06-1373
-
A. Ma, M. Boulton, B. Zhao, C. Connon, J. Cai, and J. Albon A role for notch signaling in human corneal epithelial cell differentiation and proliferation Invest. Ophthalmol. Visual Sci. 48 2007 3576 3585 (Pubitemid 351261092)
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, Issue.8
, pp. 3576-3585
-
-
Ma, A.1
Boulton, M.2
Zhao, B.3
Connon, C.4
Cai, J.5
Albon, J.6
-
25
-
-
0035853118
-
P63 identifies keratinocyte stem cells
-
DOI 10.1073/pnas.061032098
-
G. Pellegrini, E. Dellambra, O. Golisano, E. Martinelli, I. Fantozzi, S. Bondanza, D. Ponzin, F. McKeon, and M. De Luca p63 identifies keratinocyte stem cells Proc. Natl. Acad. Sci. USA 98 2001 3156 3161 (Pubitemid 32220815)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.6
, pp. 3156-3161
-
-
Pellegrini, G.1
Dellambra, E.2
Golisano, O.3
Martinelli, E.4
Fantozzi, I.5
Bondanza, S.6
Ponzin, D.7
McKeon, F.8
De Luca, M.9
-
26
-
-
33846929401
-
N-cadherin is expressed by putative stem/progenitor cells and melanocytes in the human limbal epithelial stem cell niche
-
DOI 10.1634/stemcells.2006-0167
-
R. Hayashi, M. Yamato, H. Sugiyama, T. Sumide, J. Yang, T. Okano, Y. Tano, and K. Nishida N-cadherin is expressed by putative stem/progenitor cells and melanocytes in the human limbal epithelial stem cell niche Stem Cells 25 2007 289 296 (Pubitemid 46232782)
-
(2007)
Stem Cells
, vol.25
, Issue.2
, pp. 289-296
-
-
Hayashi, R.1
Yamato, M.2
Sugiyama, H.3
Sumide, T.4
Yang, J.5
Okano, T.6
Tano, Y.7
Nishida, K.8
-
27
-
-
0024523631
-
Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
-
DOI 10.1016/0092-8674(89)90958-6
-
G. Cotsarelis, S.Z. Cheng, G. Dong, T.T. Sun, and R.M. Lavker Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells Cell 57 1989 201 209 (Pubitemid 19112360)
-
(1989)
Cell
, vol.57
, Issue.2
, pp. 201-209
-
-
Cotsarelis, G.1
Cheng, S.-Z.2
Dong, G.3
Sun, T.-T.4
Lavker, R.M.5
-
28
-
-
0032893958
-
Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency
-
A. Yachie, Y. Niida, T. Wada, N. Igarashi, H. Kaneda, T. Toma, K. Ohta, Y. Kasahara, and S. Koizumi Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency J. Clin. Invest. 103 1999 129 135 (Pubitemid 29031171)
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.1
, pp. 129-135
-
-
Yachie, A.1
Niida, Y.2
Wada, T.3
Igarashi, N.4
Kaneda, H.5
Toma, T.6
Ohta, K.7
Kasahara, Y.8
Koizumi, S.9
-
29
-
-
34347378262
-
4 and heme-oxygenase in counter-regulating inflammation during corneal wound healing
-
DOI 10.1096/fj.06-7918com
-
B. Biteman, I.R. Hassan, E. Walker, A.J. Leedom, M. Dunn, F. Seta, M. Laniado-Schwartzman, and K. Gronert Interdependence of lipoxin A4 and heme-oxygenase in counter-regulating inflammation during corneal wound healing FASEB J. 21 2007 2257 2266 (Pubitemid 47026460)
-
(2007)
FASEB Journal
, vol.21
, Issue.9
, pp. 2257-2266
-
-
Biteman, B.1
Hassan, I.R.2
Walker, E.3
Leedom, A.J.4
Dunn, M.5
Seta, F.6
Laniado-Schwartzman, M.7
Gronert, K.8
-
30
-
-
49049095091
-
Heme oxygenase-1 induction attenuates corneal inflammation and accelerates wound healing after epithelial injury
-
K. Patil, L. Bellner, G. Cullaro, K.H. Gotlinger, M.W. Dunn, and M.L. Schwartzman Heme oxygenase-1 induction attenuates corneal inflammation and accelerates wound healing after epithelial injury Invest. Ophthalmol. Visual Sci. 49 2008 3379 3386
-
(2008)
Invest. Ophthalmol. Visual Sci.
, vol.49
, pp. 3379-3386
-
-
Patil, K.1
Bellner, L.2
Cullaro, G.3
Gotlinger, K.H.4
Dunn, M.W.5
Schwartzman, M.L.6
-
31
-
-
64249150219
-
Ebselen attenuates cisplatin-induced ROS generation through Nrf2 activation in auditory cells
-
S.J. Kim, C. Park, A.L. Han, M.J. Youn, J.H. Lee, Y. Kim, E.S. Kim, H.J. Kim, J.K. Kim, H.K. Lee, S.Y. Chung, H. So, and R. Park Ebselen attenuates cisplatin-induced ROS generation through Nrf2 activation in auditory cells Hear. Res. 251 2009 70 82
-
(2009)
Hear. Res.
, vol.251
, pp. 70-82
-
-
Kim, S.J.1
Park, C.2
Han, A.L.3
Youn, M.J.4
Lee, J.H.5
Kim, Y.6
Kim, E.S.7
Kim, H.J.8
Kim, J.K.9
Lee, H.K.10
Chung, S.Y.11
So, H.12
Park, R.13
-
32
-
-
5644257028
-
Ebselen augments its peroxidase activity by inducing nrf-2-dependent transcription
-
DOI 10.1016/j.abb.2004.07.030, PII S0003986104004333
-
V. Tamasi, J.M. Jeffries, G.E. Arteel, and K.C. Falkner Ebselen augments its peroxidase activity by inducing Nrf-2-dependent transcription Arch. Biochem. Biophys. 431 2004 161 168 (Pubitemid 39369921)
-
(2004)
Archives of Biochemistry and Biophysics
, vol.431
, Issue.2
, pp. 161-168
-
-
Tamasi, V.1
Jeffries, J.M.2
Arteel, G.E.3
Falkner, K.C.4
-
33
-
-
0037188518
-
Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors
-
DOI 10.1073/pnas.112203099
-
J.W. Fahey, X. Haristoy, P.M. Dolan, T.W. Kensler, I. Scholtus, K.K. Stephenson, P. Talalay, and A. Lozniewski Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors Proc. Natl. Acad. Sci. USA 99 2002 7610 7615 (Pubitemid 34568739)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.11
, pp. 7610-7615
-
-
Fahey, J.W.1
Haristoy, X.2
Dolan, P.M.3
Kensler, T.W.4
Scholtus, I.5
Stephenson, K.K.6
Talalay, P.7
Lozniewski, A.8
-
34
-
-
0037106099
-
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
-
R.K. Thimmulappa, K.H. Mai, S. Srisuma, T.W. Kensler, M. Yamamoto, and S. Biswal Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray Cancer Res. 62 2002 5196 5203 (Pubitemid 35033454)
-
(2002)
Cancer Research
, vol.62
, Issue.18
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
36
-
-
33644882749
-
Sulforaphane, an activator of Nrf2, suppresses cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes
-
Y. Shinkai, D. Sumi, I. Fukami, T. Ishii, and Y. Kumagai Sulforaphane, an activator of Nrf2, suppresses cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes FEBS Lett. 580 2006 1771 1774
-
(2006)
FEBS Lett.
, vol.580
, pp. 1771-1774
-
-
Shinkai, Y.1
Sumi, D.2
Fukami, I.3
Ishii, T.4
Kumagai, Y.5
|