메뉴 건너뛰기




Volumn 5, Issue 3, 2013, Pages 166-175

CyclinB1/Cdk1 phosphorylates mitochondrial antioxidant MnSOD in cell adaptive response to radiation stress

Author keywords

CyclinB1 Cdk1; MnSOD; radioadaptive response

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE 1; MANGANESE SUPEROXIDE DISMUTASE;

EID: 84877994984     PISSN: 16742788     EISSN: 17594685     Source Type: Journal    
DOI: 10.1093/jmcb/mjs062     Document Type: Article
Times cited : (65)

References (53)
  • 1
    • 34247232176 scopus 로고    scopus 로고
    • Phosphorylation of caspase-9 by CDK1/ cyclin B1 protects mitotic cells against apoptosis
    • Allan, L.A., and Clarke, P.R. (2007). Phosphorylation of caspase-9 by CDK1/ cyclin B1 protects mitotic cells against apoptosis. Mol. Cell 26, 301-310.
    • (2007) Mol. Cell , vol.26 , pp. 301-310
    • Allan, L.A.1    Clarke, P.R.2
  • 2
    • 84860277633 scopus 로고    scopus 로고
    • Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polgamma against UV-induced inactivation
    • Bakthavatchalu, V., Dey, S., Xu, Y., et al. (2012). Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polgamma against UV-induced inactivation. Oncogene 31, 2129-2139.
    • (2012) Oncogene , vol.31 , pp. 2129-2139
    • Bakthavatchalu, V.1    Dey, S.2    Xu, Y.3
  • 3
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban, R.S., Nemoto, S., and Finkel, T. (2005). Mitochondria, oxidants, and aging. Cell 120, 483-495.
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 4
    • 0026688441 scopus 로고
    • The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles
    • Borgstahl, G.E., Parge, H.E., Hickey, M.J., et al. (1992). The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles. Cell 71, 107-118.
    • (1992) Cell , vol.71 , pp. 107-118
    • Borgstahl, G.E.1    Parge, H.E.2    Hickey, M.J.3
  • 5
    • 70349799010 scopus 로고    scopus 로고
    • The cell cycle is a redox cycle: Linking phase-specific targets to cell fate
    • Burhans, W.C., and Heintz, N.H. (2009). The cell cycle is a redox cycle: linking phase-specific targets to cell fate. Free Radic. Biol. Med. 47, 1282-1293.
    • (2009) Free Radic. Biol. Med. , vol.47 , pp. 1282-1293
    • Burhans, W.C.1    Heintz, N.H.2
  • 6
    • 33847212405 scopus 로고    scopus 로고
    • Yeast mitochondrial division and distribution require the cortical num1 protein
    • Cerveny, K.L., Studer, S.L., Jensen, R.E., et al. (2007). Yeast mitochondrial division and distribution require the cortical num1 protein. Dev. Cell 12, 363-375.
    • (2007) Dev. Cell , vol.12 , pp. 363-375
    • Cerveny, K.L.1    Studer, S.L.2    Jensen, R.E.3
  • 7
    • 0037067763 scopus 로고    scopus 로고
    • Regulation of peroxiredoxin i activity by Cdc2-mediated phosphorylation
    • Chang, T.S., Jeong, W., Choi, S.Y., et al. (2002). Regulation of peroxiredoxin I activity by Cdc2-mediated phosphorylation. J. Biol. Chem. 277, 25370-25376.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25370-25376
    • Chang, T.S.1    Jeong, W.2    Choi, S.Y.3
  • 8
    • 0842278331 scopus 로고    scopus 로고
    • Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
    • Chipuk, J.E., Kuwana, T., Bouchier-Hayes, L., et al. (2004). Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303, 1010-1014.
    • (2004) Science , vol.303 , pp. 1010-1014
    • Chipuk, J.E.1    Kuwana, T.2    Bouchier-Hayes, L.3
  • 9
    • 68949212379 scopus 로고    scopus 로고
    • Lysine acetylation targets protein complexes and co-regulates major cellular functions
    • Choudhary, C., Kumar, C., Gnad, F., et al. (2009). Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-840.
    • (2009) Science , vol.325 , pp. 834-840
    • Choudhary, C.1    Kumar, C.2    Gnad, F.3
  • 10
    • 0027405704 scopus 로고
    • Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells
    • Church, S.L., Grant, J.W., Ridnour, L.A., et al. (1993). Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells. Proc. Natl Acad. Sci. USA 90, 3113-3117.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 3113-3117
    • Church, S.L.1    Grant, J.W.2    Ridnour, L.A.3
  • 11
    • 22444444227 scopus 로고    scopus 로고
    • Manganese transport and trafficking: Lessons learned from Saccharomyces cerevisiae
    • Culotta, V.C., Yang, M., and Hall, M.D. (2005). Manganese transport and trafficking: lessons learned from Saccharomyces cerevisiae. Eukaryot. Cell 4, 1159-1165.
    • (2005) Eukaryot. Cell , vol.4 , pp. 1159-1165
    • Culotta, V.C.1    Yang, M.2    Hall, M.D.3
  • 12
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing an identity crisis
    • Elledge, S.J. (1996). Cell cycle checkpoints: preventing an identity crisis. Science 274, 1664-1672.
    • (1996) Science , vol.274 , pp. 1664-1672
    • Elledge, S.J.1
  • 13
    • 0033809159 scopus 로고    scopus 로고
    • Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnSOD)-deficient mice is corrected by human manganese superoxide dismutaseplasmid/ liposome (SOD2-PL) intratracheal gene therapy
    • Epperly, M.W., Epstein, C.J., Travis, E.L., et al. (2000a). Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnSOD)-deficient mice is corrected by human manganese superoxide dismutaseplasmid/ liposome (SOD2-PL) intratracheal gene therapy. Radiat. Res. 154, 365-374.
    • (2000) Radiat. Res. , vol.154 , pp. 365-374
    • Epperly, M.W.1    Epstein, C.J.2    Travis, E.L.3
  • 14
    • 0033920418 scopus 로고    scopus 로고
    • Plasmid/liposome transfer of the human manganese superoxide dismutase transgene prevents ionizing irradiation-induced apoptosis in human esophagus organ explant culture
    • Epperly, M.W., Sikora, C., Defilippi, S., et al. (2000b). Plasmid/liposome transfer of the human manganese superoxide dismutase transgene prevents ionizing irradiation-induced apoptosis in human esophagus organ explant culture. Int. J. Cancer 90, 128-137.
    • (2000) Int. J. Cancer , vol.90 , pp. 128-137
    • Epperly, M.W.1    Sikora, C.2    Defilippi, S.3
  • 15
    • 34248221984 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and manganese superoxide dismutase mediate adaptive radioresistance in low-dose irradiated mouse skin epithelial cells
    • Fan, M., Ahmed, K.M., Coleman, M.C., et al. (2007). Nuclear factor-kappaB and manganese superoxide dismutase mediate adaptive radioresistance in low-dose irradiated mouse skin epithelial cells. Cancer Res. 67, 3220-3228.
    • (2007) Cancer Res. , vol.67 , pp. 3220-3228
    • Fan, M.1    Ahmed, K.M.2    Coleman, M.C.3
  • 16
    • 0033135367 scopus 로고    scopus 로고
    • Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice
    • Fujimura, M., Morita-Fujimura, Y., Kawase, M., et al. (1999). Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J. Neurosci. 19, 3414-3422.
    • (1999) J. Neurosci. , vol.19 , pp. 3414-3422
    • Fujimura, M.1    Morita-Fujimura, Y.2    Kawase, M.3
  • 17
    • 10744229156 scopus 로고    scopus 로고
    • Expression of ErbB2 enhances radiation-induced NF-kappaB activation
    • Guo, G., Wang, T., Gao, Q., et al. (2004). Expression of ErbB2 enhances radiation-induced NF-kappaB activation. Oncogene 23, 535-545.
    • (2004) Oncogene , vol.23 , pp. 535-545
    • Guo, G.1    Wang, T.2    Gao, Q.3
  • 18
    • 70349306566 scopus 로고    scopus 로고
    • Direct, real-time monitoring of superoxide generation in isolated mitochondria
    • Henderson, J.R., Swalwell, H., Boulton, S., et al. (2009). Direct, real-time monitoring of superoxide generation in isolated mitochondria. Free Radic. Res. 43, 796-802.
    • (2009) Free Radic. Res. , vol.43 , pp. 796-802
    • Henderson, J.R.1    Swalwell, H.2    Boulton, S.3
  • 19
    • 77955298346 scopus 로고    scopus 로고
    • Manganese superoxide dismutase versus p53: The mitochondrial center
    • Holley, A.K., Dhar, S.K., and St Clair, D.K. (2010). Manganese superoxide dismutase versus p53: the mitochondrial center. Ann. NY Acad. Sci. 1201, 72-78.
    • (2010) Ann. NY Acad. Sci. , vol.1201 , pp. 72-78
    • Holley, A.K.1    Dhar, S.K.2    St. Clair, D.K.3
  • 20
    • 0029032567 scopus 로고
    • Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase
    • Li, J.J., Oberley, L.W., St Clair, D.K., et al. (1995). Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase. Oncogene 10, 1989-2000.
    • (1995) Oncogene , vol.10 , pp. 1989-2000
    • Li, J.J.1    Oberley, L.W.2    St Clair, D.K.3
  • 21
    • 34249065507 scopus 로고    scopus 로고
    • Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progression
    • Lindqvist, A., van Zon, W., Karlsson Rosenthal, C., et al. (2007). Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progression. PLoS Biol. 5, e123.
    • (2007) PLoS Biol , vol.5
    • Lindqvist, A.1    Van Zon, W.2    Karlsson Rosenthal, C.3
  • 22
    • 0015056379 scopus 로고
    • An enzyme-based theory of obligate anaerobiosis: The physiological function of superoxide dismutase
    • McCord, J.M., Keele, B.B., Jr., and Fridovich, I. (1971). An enzyme-based theory of obligate anaerobiosis: the physiological function of superoxide dismutase. Proc. Natl Acad. Sci. USA 68, 1024-1027.
    • (1971) Proc. Natl Acad. Sci. USA , vol.68 , pp. 1024-1027
    • McCord, J.M.1    Keele Jr., B.B.2    Fridovich, I.3
  • 23
    • 33847185842 scopus 로고    scopus 로고
    • A redox cycle within the cell cycle: Ring in the old with the new
    • Menon, S.G., and Goswami, P.C. (2007). A redox cycle within the cell cycle: ring in the old with the new. Oncogene 26, 1101-1109.
    • (2007) Oncogene , vol.26 , pp. 1101-1109
    • Menon, S.G.1    Goswami, P.C.2
  • 24
    • 0037349289 scopus 로고    scopus 로고
    • P53 has a direct apoptogenic role at the mitochondria
    • Mihara, M., Erster, S., Zaika, A., et al. (2003). p53 has a direct apoptogenic role at the mitochondria. Mol. Cell 11, 577-590.
    • (2003) Mol. Cell , vol.11 , pp. 577-590
    • Mihara, M.1    Erster, S.2    Zaika, A.3
  • 25
    • 38349158077 scopus 로고    scopus 로고
    • Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy
    • Mukhopadhyay, P., Rajesh, M., Hasko, G., et al. (2007). Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy. Nat. Protoc. 2, 2295-2301.
    • (2007) Nat. Protoc. , vol.2 , pp. 2295-2301
    • Mukhopadhyay, P.1    Rajesh, M.2    Hasko, G.3
  • 26
    • 43449138198 scopus 로고    scopus 로고
    • Maintenance of manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by repeated administration of the free thiol form of amifostine
    • Murley, J.S., Nantajit, D., Baker, K.L., et al. (2008). Maintenance of manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by repeated administration of the free thiol form of amifostine. Radiat. Res. 169, 495-505.
    • (2008) Radiat. Res. , vol.169 , pp. 495-505
    • Murley, J.S.1    Nantajit, D.2    Baker, K.L.3
  • 27
    • 77957857877 scopus 로고    scopus 로고
    • Cyclin B1/Cdk1 phosphorylation of mitochondrial p53 induces anti-apoptotic response
    • Nantajit, D., Fan, M., Duru, N., et al. (2010). Cyclin B1/Cdk1 phosphorylation of mitochondrial p53 induces anti-apoptotic response. PLoS One 5, e12341.
    • (2010) PLoS One , vol.5
    • Nantajit, D.1    Fan, M.2    Duru, N.3
  • 28
    • 0029317904 scopus 로고
    • Cyclin-dependent protein kinases: Key regulators of the eukaryotic cell cycle
    • Nigg, E.A. (1995). Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. Bioessays 17, 471-480.
    • (1995) Bioessays , vol.17 , pp. 471-480
    • Nigg, E.A.1
  • 29
    • 0018749490 scopus 로고
    • Role of superoxide dismutase in cancer: A review
    • Oberley, L.W., and Buettner, G.R. (1979). Role of superoxide dismutase in cancer: a review. Cancer Res. 39, 1141-1149.
    • (1979) Cancer Res. , vol.39 , pp. 1141-1149
    • Oberley, L.W.1    Buettner, G.R.2
  • 30
    • 0024596776 scopus 로고
    • Manganese superoxide dismutase in normal and transformed human embryonic lung fibroblasts
    • Oberley, L.W., McCormick, M.L., Sierra-Rivera, E., et al. (1989). Manganese superoxide dismutase in normal and transformed human embryonic lung fibroblasts. Free Radic. Biol. Med. 6, 379-384.
    • (1989) Free Radic. Biol. Med. , vol.6 , pp. 379-384
    • Oberley, L.W.1    McCormick, M.L.2    Sierra-Rivera, E.3
  • 31
    • 0034664733 scopus 로고    scopus 로고
    • P53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
    • Oda, K., Arakawa, H., Tanaka, T., et al. (2000). p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell 102, 849-862.
    • (2000) Cell , vol.102 , pp. 849-862
    • Oda, K.1    Arakawa, H.2    Tanaka, T.3
  • 32
    • 79959541505 scopus 로고    scopus 로고
    • Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress
    • Ozden, O., Park, S.H., Kim, H.S., et al. (2011). Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress. Aging (Albany NY) 3, 102-107.
    • (2011) Aging (Albany NY) , vol.3 , pp. 102-107
    • Ozden, O.1    Park, S.H.2    Kim, H.S.3
  • 33
    • 30444449969 scopus 로고    scopus 로고
    • Mitosis: A matter of getting rid of the right protein at the right time
    • Pines, J. (2006). Mitosis: a matter of getting rid of the right protein at the right time. Trends Cell Biol. 16, 55-63.
    • (2006) Trends Cell Biol. , vol.16 , pp. 55-63
    • Pines, J.1
  • 34
    • 0036137588 scopus 로고    scopus 로고
    • Peroxiredoxin, a novel family of peroxidases
    • Rhee, S.G., Kang, S.W., Chang, T.S., et al. (2001). Peroxiredoxin, a novel family of peroxidases. IUBMB Life 52, 35-41.
    • (2001) IUBMB Life , vol.52 , pp. 35-41
    • Rhee, S.G.1    Kang, S.W.2    Chang, T.S.3
  • 35
    • 0034717570 scopus 로고    scopus 로고
    • Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex
    • Rudner, A.D., and Murray, A.W. (2000). Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex. J. Cell Biol. 149, 1377-1390.
    • (2000) J. Cell Biol. , vol.149 , pp. 1377-1390
    • Rudner, A.D.1    Murray, A.W.2
  • 36
    • 24044461088 scopus 로고    scopus 로고
    • Manganese superoxide dismutase protects the proliferative capacity of confluent normal human fibroblasts
    • Sarsour, E.H., Agarwal, M., Pandita, T.K., et al. (2005). Manganese superoxide dismutase protects the proliferative capacity of confluent normal human fibroblasts. J. Biol. Chem. 280, 18033-18041.
    • (2005) J. Biol. Chem. , vol.280 , pp. 18033-18041
    • Sarsour, E.H.1    Agarwal, M.2    Pandita, T.K.3
  • 37
    • 43449104237 scopus 로고    scopus 로고
    • Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth
    • Sarsour, E.H., Venkataraman, S., Kalen, A.L., et al. (2008). Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth. Aging Cell 7, 405-417.
    • (2008) Aging Cell , vol.7 , pp. 405-417
    • Sarsour, E.H.1    Venkataraman, S.2    Kalen, A.L.3
  • 38
    • 0025572247 scopus 로고
    • Cyclin activation of p34cdc2
    • Solomon, M.J., Glotzer, M., Lee, T.H., et al. (1990). Cyclin activation of p34cdc2. Cell 63, 1013-1024.
    • (1990) Cell , vol.63 , pp. 1013-1024
    • Solomon, M.J.1    Glotzer, M.2    Lee, T.H.3
  • 39
    • 3042736846 scopus 로고    scopus 로고
    • Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: A unifying concept in stress response biology
    • Spitz, D.R., Azzam, E.I., Li, J.J., et al. (2004). Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: a unifying concept in stress response biology. Cancer Metastasis Rev. 23, 311-322.
    • (2004) Cancer Metastasis Rev. , vol.23 , pp. 311-322
    • Spitz, D.R.1    Azzam, E.I.2    Li, J.J.3
  • 40
    • 0026033905 scopus 로고
    • Complementary DNA encoding human colon cancer manganese superoxide dismutase and the expression of its gene in human cells
    • St Clair, D.K., and Holland, J.C. (1991). Complementary DNA encoding human colon cancer manganese superoxide dismutase and the expression of its gene in human cells. Cancer Res. 51, 939-943.
    • (1991) Cancer Res. , vol.51 , pp. 939-943
    • St Clair, D.K.1    Holland, J.C.2
  • 41
    • 0024578791 scopus 로고
    • Irradiation increases superoxide dismutase in rat intestinal smooth muscle
    • Summers, R.W., Maves, B.V., Reeves, R.D., et al. (1989). Irradiation increases superoxide dismutase in rat intestinal smooth muscle. Free Radic. Biol. Med. 6, 261-270.
    • (1989) Free Radic. Biol. Med. , vol.6 , pp. 261-270
    • Summers, R.W.1    Maves, B.V.2    Reeves, R.D.3
  • 42
    • 0242300176 scopus 로고    scopus 로고
    • Targets of the cyclindependent kinase Cdk1
    • Ubersax, J.A., Woodbury, E.L., Quang, P.N., et al. (2003). Targets of the cyclindependent kinase Cdk1. Nature 425, 859-864.
    • (2003) Nature , vol.425 , pp. 859-864
    • Ubersax, J.A.1    Woodbury, E.L.2    Quang, P.N.3
  • 43
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • van den Heuvel, S., and Harlow, E. (1993). Distinct roles for cyclin-dependent kinases in cell cycle control. Science 262, 2050-2054.
    • (1993) Science , vol.262 , pp. 2050-2054
    • Van Den Heuvel, S.1    Harlow, E.2
  • 44
    • 0034988397 scopus 로고    scopus 로고
    • Oxidative damage to mitochondria and aging
    • Van Remmen, H., and Richardson, A. (2001). Oxidative damage to mitochondria and aging. Exp. Gerontol. 36, 957-968.
    • (2001) Exp. Gerontol. , vol.36 , pp. 957-968
    • Van Remmen, H.1    Richardson, A.2
  • 45
    • 0034838078 scopus 로고    scopus 로고
    • Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis
    • Van Remmen, H., Williams, M.D., Guo, Z., et al. (2001). Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis. Am. J. Physiol. Heart Circ. Physiol. 281, H1422-H1432.
    • (2001) Am. J. Physiol. Heart Circ. Physiol. , vol.281
    • Van Remmen, H.1    Williams, M.D.2    Guo, Z.3
  • 46
    • 2942556985 scopus 로고    scopus 로고
    • Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
    • Van Remmen, H., Qi, W., Sabia, M., et al. (2004). Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. Free Radic. Biol. Med. 36, 1625-1634.
    • (2004) Free Radic. Biol. Med. , vol.36 , pp. 1625-1634
    • Van Remmen, H.1    Qi, W.2    Sabia, M.3
  • 47
    • 75149164344 scopus 로고    scopus 로고
    • Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue
    • Weydert, C.J., and Cullen, J.J. (2010). Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue. Nat. Protoc. 5, 51-66.
    • (2010) Nat. Protoc. , vol.5 , pp. 51-66
    • Weydert, C.J.1    Cullen, J.J.2
  • 48
    • 0032561328 scopus 로고    scopus 로고
    • Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice
    • Williams, M.D., Van Remmen, H., Conrad, C.C., et al. (1998). Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice. J. Biol. Chem. 273, 28510-28515.
    • (1998) J. Biol. Chem. , vol.273 , pp. 28510-28515
    • Williams, M.D.1    Van Remmen, H.2    Conrad, C.C.3
  • 49
    • 0036499459 scopus 로고    scopus 로고
    • Transcriptional regulation of the human manganese superoxide dismutase gene: The role of specificity protein 1 (Sp1) and activating protein-2 (AP-2)
    • Xu, Y., Porntadavity, S., and St Clair, D.K. (2002). Transcriptional regulation of the human manganese superoxide dismutase gene: the role of specificity protein 1 (Sp1) and activating protein-2 (AP-2). Biochem. J. 362, 401-412.
    • (2002) Biochem. J. , vol.362 , pp. 401-412
    • Xu, Y.1    Porntadavity, S.2    St. Clair, D.K.3
  • 50
    • 77956551895 scopus 로고    scopus 로고
    • Loss of manganese superoxide dismutase leads to abnormal growth and signal transduction in mouse embryonic fibroblasts
    • Zhang, Y., Zhang, H.M., Shi, Y., et al. (2010). Loss of manganese superoxide dismutase leads to abnormal growth and signal transduction in mouse embryonic fibroblasts. Free Radic. Biol. Med. 49, 1255-1262.
    • (2010) Free Radic. Biol. Med. , vol.49 , pp. 1255-1262
    • Zhang, Y.1    Zhang, H.M.2    Shi, Y.3
  • 51
    • 85047698438 scopus 로고    scopus 로고
    • Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model
    • Zhao, Y., Oberley, T.D., Chaiswing, L., et al. (2002). Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model. Oncogene 21, 3836-3846.
    • (2002) Oncogene , vol.21 , pp. 3836-3846
    • Zhao, Y.1    Oberley, T.D.2    Chaiswing, L.3
  • 52
    • 18144382261 scopus 로고    scopus 로고
    • P53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase
    • Zhao, Y., Chaiswing, L., Velez, J.M., et al. (2005). p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. Cancer Res. 65, 3745-3750.
    • (2005) Cancer Res. , vol.65 , pp. 3745-3750
    • Zhao, Y.1    Chaiswing, L.2    Velez, J.M.3
  • 53
    • 0031035767 scopus 로고    scopus 로고
    • Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase
    • Zhong, W., Oberley, L.W., Oberley, T.D., et al. (1997). Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase. Oncogene 14, 481-490.
    • (1997) Oncogene , vol.14 , pp. 481-490
    • Zhong, W.1    Oberley, L.W.2    Oberley, T.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.