Microsomal prostaglandin E synthase-1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease-like pathology in a mouse model

Journal of Neuroscience Research

Volumn 91, Issue 7, 2013, Pages 909-919

  Akitake, Yoshiharu ^a   Nakatani, Yoshihito ^b   Kamei, Daisuke ^b   Hosokawa, Masato ^a,c   Akatsu, Hiroyasu ^d   Uematsu, Satoshi ^e   Akira, Shizuo ^e   Kudo, Ichiro ^b,f   Hara, Shuntaro ^b   Takahashi, Mitsuo ^a,d  

^a FUKUOKA UNIVERSITY   (Japan)

^b SHOWA UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d Fukushimura Hospital   (Japan)

^e OSAKA UNIVERSITY   (Japan)

^f NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

amyloid; Alzheimer's disease; Microglia; Microsomal prostaglandin E synthase 1; Prostaglandin

Indexed keywords

AMYLOID BETA PROTEIN; PROSTAGLANDIN E SYNTHASE 1;

AGED; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FRONTAL LOBE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LEARNING DISORDER; MALE; MAZE TEST; MICROGLIA; MOUSE; NONHUMAN; PARIETAL LOBE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CASE-CONTROL STUDIES; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PLAQUE, AMYLOID;

EID: 84877926316     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23217     Document Type: Article

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