Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis

Oncogene

Volumn 31, Issue 24, 2012, Pages 2943-2952

  Sasaki, Y ^a   Kamei, D ^a   Ishikawa, Y ^b   Ishii, T ^b   Uematsu, S ^c   Akira, S ^c   Murakami, M ^a,d   Hara, S ^a  

^a SHOWA UNIVERSITY   (Japan)

^b TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

colon cancer; macrophage; mPGES 1; prostaglandin E 2

Indexed keywords

AZOXYMETHANE; BETA CATENIN; CARCINOGEN; CHEMOKINE; PROSTACYCLIN; PROSTAGLANDIN D2; PROSTAGLANDIN E SYNTHASE 1;

ABERRANT CRYPT FOCUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CANCER STAGING; CANCER TRANSPLANTATION; CELL ISOLATION; COCULTURE; COLON CARCINOGENESIS; COLORECTAL CANCER; COLORECTAL POLYP; CONTROLLED STUDY; GENE DELETION; GENE OVEREXPRESSION; IN VITRO STUDY; KNOCKOUT MOUSE; MACROPHAGE; MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; TRANSGENICS; TUMOR CELL; TUMOR GROWTH; TUMOR VOLUME; WILD TYPE;

ABERRANT CRYPT FOCI; ADENOCARCINOMA; ANIMALS; AZOXYMETHANE; BETA CATENIN; CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; COCULTURE TECHNIQUES; COLONIC NEOPLASMS; COLONIC POLYPS; CYTOKINES; GENE EXPRESSION PROFILING; INTRAMOLECULAR OXIDOREDUCTASES; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSOMES; NEOPLASM TRANSPLANTATION; PROSTAGLANDINS;

MUS;

EID: 84862331459     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.472     Document Type: Article

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