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Volumn 8, Issue 5, 2013, Pages

Munc18c in Adipose Tissue Is Downregulated in Obesity and Is Associated with Insulin

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LIVER X RECEPTOR AGONIST; LIVER X RECEPTOR ALPHA; MUNC18 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL;

EID: 84877916580     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063937     Document Type: Article
Times cited : (16)

References (49)
  • 1
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Review
    • Libby P, Ridker PM, Maseri A (2002) Inflammation and atherosclerosis. Circulation 105: 1135-1143. Review.
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 2
    • 0028230349 scopus 로고
    • Insulin stimulation of GLUT-4 translocation: a model for regulated recycling
    • James DE, Piper RC, Slot JW, (1994) Insulin stimulation of GLUT-4 translocation: a model for regulated recycling. Trends Cell Biol 4: 120-126.
    • (1994) Trends Cell Biol , vol.4 , pp. 120-126
    • James, D.E.1    Piper, R.C.2    Slot, J.W.3
  • 3
    • 0029113787 scopus 로고
    • Molecular actions of insulin on glucose transport
    • Review
    • Czech MP (1995) Molecular actions of insulin on glucose transport. Annu Rev Nutr 15: 441-471. Review.
    • (1995) Annu Rev Nutr , vol.15 , pp. 441-471
    • Czech, M.P.1
  • 4
    • 0028014550 scopus 로고
    • Regulation of expression of glucose transporters by glucose: a review of studies in vivo and in cell cultures
    • Review
    • Klip A, Tsakiridis T, Marette A, Ortiz PA (1994) Regulation of expression of glucose transporters by glucose: a review of studies in vivo and in cell cultures. FASEB J 8: 43-53. Review.
    • (1994) FASEB J , vol.8 , pp. 43-53
    • Klip, A.1    Tsakiridis, T.2    Marette, A.3    Ortiz, P.A.4
  • 5
    • 0035685534 scopus 로고    scopus 로고
    • Molecular machinery involved in the insulin regulated fusion of GLUT4-containing vesicles with the plasma membrane
    • Review
    • Thurmond DC, Pessin JE (2001) Molecular machinery involved in the insulin regulated fusion of GLUT4-containing vesicles with the plasma membrane. Mol Membr Biol 18: 237-245. Review.
    • (2001) Mol Membr Biol , vol.18 , pp. 237-245
    • Thurmond, D.C.1    Pessin, J.E.2
  • 6
    • 0033913213 scopus 로고    scopus 로고
    • Signaling pathways in insulin action: molecular targets of insulin resistance
    • Review
    • Pessin JE, Saltiel AR (2000) Signaling pathways in insulin action: molecular targets of insulin resistance. J Clin Invest 106: 165-169. Review.
    • (2000) J Clin Invest , vol.106 , pp. 165-169
    • Pessin, J.E.1    Saltiel, A.R.2
  • 7
    • 0033696020 scopus 로고    scopus 로고
    • Mechanism and regulation of GLUT-4 vesicle fusion in muscle and fat cells
    • Review
    • Foster LJ, Klip A (2000) Mechanism and regulation of GLUT-4 vesicle fusion in muscle and fat cells. Am J Physiol Cell Physiol 279: C877-C890. Review.
    • (2000) Am J Physiol Cell Physiol , vol.279
    • Foster, L.J.1    Klip, A.2
  • 8
    • 0034677749 scopus 로고    scopus 로고
    • Role of SNAP23 in insulin-induced translocation of GLUT4 in 3T3-L1 adipocytes: mediation of complex formation between syntaxin4 and VAMP2
    • Kawanishi M, Tamori Y, Okazawa H, Araki S, Shinoda H, et al. (2000) Role of SNAP23 in insulin-induced translocation of GLUT4 in 3T3-L1 adipocytes: mediation of complex formation between syntaxin4 and VAMP2. J Biol Chem 275: 8240-7.
    • (2000) J Biol Chem , vol.275 , pp. 8240-8247
    • Kawanishi, M.1    Tamori, Y.2    Okazawa, H.3    Araki, S.4    Shinoda, H.5
  • 9
    • 0030055490 scopus 로고    scopus 로고
    • Syntaxin 4 in 3T3-L1 adipocytes: regulation by insulin and participation in insulindependent glucose transport
    • Volchuk A, Wang Q, Ewart HS, Liu Z, He L, et al. (1996) Syntaxin 4 in 3T3-L1 adipocytes: regulation by insulin and participation in insulindependent glucose transport. Mol Biol Cell 7: 1075-82.
    • (1996) Mol Biol Cell , vol.7 , pp. 1075-1082
    • Volchuk, A.1    Wang, Q.2    Ewart, H.S.3    Liu, Z.4    He, L.5
  • 10
    • 0035000661 scopus 로고    scopus 로고
    • Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance
    • Yang C, Coker KJ, Kim K, Mora S, Thurmond DC, et al. (2001) Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance. J Clin Invest 107: 1311-8.
    • (2001) J Clin Invest , vol.107 , pp. 1311-1318
    • Yang, C.1    Coker, K.J.2    Kim, K.3    Mora, S.4    Thurmond, D.C.5
  • 11
    • 0030969764 scopus 로고    scopus 로고
    • Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4
    • Tellam JT, Macaulay SL, McIntosh S, Hewish DR, Ward CW, et al. (1997) Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4. J Biol Chem 272: 6179-86.
    • (1997) J Biol Chem , vol.272 , pp. 6179-6186
    • Tellam, J.T.1    Macaulay, S.L.2    McIntosh, S.3    Hewish, D.R.4    Ward, C.W.5
  • 12
    • 0028998826 scopus 로고
    • A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic
    • Hata Y, Sudhof TC, (1995) A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic. J Biol Chem 270: 13022-8.
    • (1995) J Biol Chem , vol.270 , pp. 13022-13028
    • Hata, Y.1    Sudhof, T.C.2
  • 15
    • 0032584609 scopus 로고    scopus 로고
    • Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes
    • Tamori Y, Kawanishi M, Niki T, Shinoda H, Araki S, et al. (1998) Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes. J Biol Chem 273: 19740-6.
    • (1998) J Biol Chem , vol.273 , pp. 19740-19746
    • Tamori, Y.1    Kawanishi, M.2    Niki, T.3    Shinoda, H.4    Araki, S.5
  • 16
    • 0032509214 scopus 로고    scopus 로고
    • Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes
    • Thurmond DC, Ceresa BP, Okada S, Elmendorf JS, Coker K, et al. (1998) Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes. J Biol Chem 273: 33876-83.
    • (1998) J Biol Chem , vol.273 , pp. 33876-33883
    • Thurmond, D.C.1    Ceresa, B.P.2    Okada, S.3    Elmendorf, J.S.4    Coker, K.5
  • 17
    • 0033988446 scopus 로고    scopus 로고
    • Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles
    • Thurmond DC, Kanzaki M, Khan AH, Pessin JE, (2000) Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles. Mol Cell Biol 20: 379-88.
    • (2000) Mol Cell Biol , vol.20 , pp. 379-388
    • Thurmond, D.C.1    Kanzaki, M.2    Khan, A.H.3    Pessin, J.E.4
  • 18
    • 0026582816 scopus 로고
    • The unc-18 gene encodes a novel protein affecting the kinetics of acetylcholine metabolism in the nematode Caenorhabditis elegans
    • Hosono R, Hekimi S, Kamiya Y, Sassa T, Murakami S, et al. (1992) The unc-18 gene encodes a novel protein affecting the kinetics of acetylcholine metabolism in the nematode Caenorhabditis elegans. J Neurochem 58: 1517-25.
    • (1992) J Neurochem , vol.58 , pp. 1517-1525
    • Hosono, R.1    Hekimi, S.2    Kamiya, Y.3    Sassa, T.4    Murakami, S.5
  • 19
    • 0027938531 scopus 로고
    • Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission
    • Harrison SD, Broadie K, van de Goor J, Rubin GM, (1994) Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission. Neuron 13: 555-66.
    • (1994) Neuron , vol.13 , pp. 555-566
    • Harrison, S.D.1    Broadie, K.2    van de Goor, J.3    Rubin, G.M.4
  • 20
    • 0032836484 scopus 로고    scopus 로고
    • Membrane fusion and exocytosis
    • Review
    • Jahn R, Südhof TC (1999) Membrane fusion and exocytosis. Annu Rev Biochem 68: 863-911. Review.
    • (1999) Annu Rev Biochem , vol.68 , pp. 863-911
    • Jahn, R.1    Südhof, T.C.2
  • 21
    • 0043268827 scopus 로고    scopus 로고
    • Insulin resistance in tetracycline-repressible Munc18c transgenic mice
    • Spurlin BA, Thomas RM, Nevins AK, Kim HJ, Kim YJ, et al. (2003) Insulin resistance in tetracycline-repressible Munc18c transgenic mice. Diabetes 52: 1910-7.
    • (2003) Diabetes , vol.52 , pp. 1910-1917
    • Spurlin, B.A.1    Thomas, R.M.2    Nevins, A.K.3    Kim, H.J.4    Kim, Y.J.5
  • 22
    • 14644408047 scopus 로고    scopus 로고
    • Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance
    • Oh E, Spurlin BA, Pessin JE, Thurmond DC, (2005) Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance. Diabetes 54: 638-47.
    • (2005) Diabetes , vol.54 , pp. 638-647
    • Oh, E.1    Spurlin, B.A.2    Pessin, J.E.3    Thurmond, D.C.4
  • 23
    • 37549069753 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Munc18c regulates platelet-derived growth factor-stimulated glucose transporter 4 translocation in 3T3L1 adipocytes
    • Umahara M, Okada S, Yamada E, Saito T, Ohshima K, et al. (2008) Tyrosine phosphorylation of Munc18c regulates platelet-derived growth factor-stimulated glucose transporter 4 translocation in 3T3L1 adipocytes. Endocrinology 149: 40-9.
    • (2008) Endocrinology , vol.149 , pp. 40-49
    • Umahara, M.1    Okada, S.2    Yamada, E.3    Saito, T.4    Ohshima, K.5
  • 24
    • 79955517215 scopus 로고    scopus 로고
    • Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis
    • Jewell JL, Oh E, Ramalingam L, Kalwat MA, Tagliabracci VS, et al. (2011) Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis. J Cell Biol 193: 185-99.
    • (2011) J Cell Biol , vol.193 , pp. 185-199
    • Jewell, J.L.1    Oh, E.2    Ramalingam, L.3    Kalwat, M.A.4    Tagliabracci, V.S.5
  • 25
    • 33749332751 scopus 로고    scopus 로고
    • Temporal dynamics of tyrosine phosphorylation in insulin signaling
    • Schmelzle K, Kane S, Gridley S, Lienhard GE, White FM, (2006) Temporal dynamics of tyrosine phosphorylation in insulin signaling. Diabetes 55: 2171-9.
    • (2006) Diabetes , vol.55 , pp. 2171-2179
    • Schmelzle, K.1    Kane, S.2    Gridley, S.3    Lienhard, G.E.4    White, F.M.5
  • 26
    • 79955671159 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4
    • Aran V, Bryant NJ, Gould GW, (2011) Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4. BMC Biochem 12: 19.
    • (2011) BMC Biochem , vol.12 , pp. 19
    • Aran, V.1    Bryant, N.J.2    Gould, G.W.3
  • 28
    • 78449300149 scopus 로고    scopus 로고
    • Obesity and insulin resistance-related changes in the expression of lipogenic and lipolytic genes in morbidly obese subjects
    • Tinahones FJ, Garrido-Sanchez L, Miranda M, García-Almeida JM, Macias-Gonzalez M, et al. (2010) Obesity and insulin resistance-related changes in the expression of lipogenic and lipolytic genes in morbidly obese subjects. Obes Surg 20: 1559-67.
    • (2010) Obes Surg , vol.20 , pp. 1559-1567
    • Tinahones, F.J.1    Garrido-Sanchez, L.2    Miranda, M.3    García-Almeida, J.M.4    Macias-Gonzalez, M.5
  • 32
    • 78650861117 scopus 로고    scopus 로고
    • Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques
    • Tang JJ, Li JG, Qi W, Qiu WW, Li PS, et al. (2011) Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques. Cell Metab 13: 44-56.
    • (2011) Cell Metab , vol.13 , pp. 44-56
    • Tang, J.J.1    Li, J.G.2    Qi, W.3    Qiu, W.W.4    Li, P.S.5
  • 35
    • 80052775605 scopus 로고    scopus 로고
    • Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice
    • Yu X, Shen N, Zhang ML, Pan FY, Wang C, et al. (2011) Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice. EMBO J 30: 3754-65.
    • (2011) EMBO J , vol.30 , pp. 3754-3765
    • Yu, X.1    Shen, N.2    Zhang, M.L.3    Pan, F.Y.4    Wang, C.5
  • 37
    • 3843061127 scopus 로고    scopus 로고
    • Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver
    • Chen G, Liang G, Ou J, Goldstein JL, Brown MS, (2004) Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc Natl Acad Sci USA 101: 11245-50.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11245-11250
    • Chen, G.1    Liang, G.2    Ou, J.3    Goldstein, J.L.4    Brown, M.S.5
  • 38
    • 33751117989 scopus 로고    scopus 로고
    • Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter through SRE motifs
    • Dif N, Euthine V, Gonnet E, Laville M, Vidal H, et al. (2006) Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter through SRE motifs. Biochem J 400: 179-88.
    • (2006) Biochem J , vol.400 , pp. 179-188
    • Dif, N.1    Euthine, V.2    Gonnet, E.3    Laville, M.4    Vidal, H.5
  • 39
    • 0037155935 scopus 로고    scopus 로고
    • Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
    • Tobin KA, Ulven SM, Schuster GU, Steineger HH, Andresen SM, et al. (2002) Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis. J Biol Chem Mar 277: 10691-7.
    • (2002) J Biol Chem Mar , vol.277 , pp. 10691-10697
    • Tobin, K.A.1    Ulven, S.M.2    Schuster, G.U.3    Steineger, H.H.4    Andresen, S.M.5
  • 40
    • 84877917131 scopus 로고    scopus 로고
    • Liver X receptors (LXRs). Part I: structure, function, regulation of activity, and role in lipid metabolism
    • Review
    • Wójcicka G, Jamroz-Wiśniewska A, Horoszewicz K, Bełtowski J (2007) Liver X receptors (LXRs). Part I: structure, function, regulation of activity, and role in lipid metabolism. Postepy Hig Med Dosw (Online) 61: 760-85. Review.
    • (2007) Postepy Hig Med Dosw (Online) , vol.61 , pp. 760-785
    • Wójcicka, G.1    Jamroz-Wiśniewska, A.2    Horoszewicz, K.3    Bełtowski, J.4
  • 41
    • 77957222438 scopus 로고    scopus 로고
    • Activation of liver X receptors with T0901317 attenuates cardiac hypertrophy in vivo
    • Kuipers I, Li J, Vreeswijk-Baudoin I, Koster J, van der Harst P, et al. (2010) Activation of liver X receptors with T0901317 attenuates cardiac hypertrophy in vivo. Eur J Heart Fail 12: 1042-50.
    • (2010) Eur J Heart Fail , vol.12 , pp. 1042-1050
    • Kuipers, I.1    Li, J.2    Vreeswijk-Baudoin, I.3    Koster, J.4    van der Harst, P.5
  • 42
    • 77249173175 scopus 로고    scopus 로고
    • DNA recognition by thyroid hormone and retinoic acid receptors: 3,4,5 rule modified
    • Phan TQ, Jow MM, Privalsky ML, (2010) DNA recognition by thyroid hormone and retinoic acid receptors: 3,4,5 rule modified. Mol Cell Endocrinol 319: 88-98.
    • (2010) Mol Cell Endocrinol , vol.319 , pp. 88-98
    • Phan, T.Q.1    Jow, M.M.2    Privalsky, M.L.3
  • 43
    • 0034669025 scopus 로고    scopus 로고
    • Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRa and LXRb
    • Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JM, et al. (2000) Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRa and LXRb. Genes Dev 14: 2819-30.
    • (2000) Genes Dev , vol.14 , pp. 2819-2830
    • Repa, J.J.1    Liang, G.2    Ou, J.3    Bashmakov, Y.4    Lobaccaro, J.M.5
  • 44
    • 84856777771 scopus 로고    scopus 로고
    • Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites
    • Boergesen M, Pedersen TÅ, Gross B, van Heeringen SJ, Hagenbeek D, et al. (2012) Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites. Mol Cell Biol 32: 852-67.
    • (2012) Mol Cell Biol , vol.32 , pp. 852-867
    • Boergesen, M.1    Pedersen, T.Å.2    Gross, B.3    van Heeringen, S.J.4    Hagenbeek, D.5
  • 45
    • 84856316797 scopus 로고    scopus 로고
    • Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages
    • Pehkonen P, Welter-Stahl L, Diwo J, Ryynänen J, Wienecke-Baldacchino A, et al. (2012) Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages. BMC Genomics 13: 50.
    • (2012) BMC Genomics , vol.13 , pp. 50
    • Pehkonen, P.1    Welter-Stahl, L.2    Diwo, J.3    Ryynänen, J.4    Wienecke-Baldacchino, A.5
  • 46
    • 84864383302 scopus 로고    scopus 로고
    • Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology
    • Moutier E, Ye T, Choukrallah MA, Urban S, Osz J, et al. (2012) Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology. J Biol Chem 287: 26328-41.
    • (2012) J Biol Chem , vol.287 , pp. 26328-26341
    • Moutier, E.1    Ye, T.2    Choukrallah, M.A.3    Urban, S.4    Osz, J.5
  • 47
    • 0037174130 scopus 로고    scopus 로고
    • Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells
    • Macaulay SL, Grusovin J, Stoichevska V, Ryan JM, Castelli LA, et al. (2002) Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells. FEBS Lett 528: 154-60.
    • (2002) FEBS Lett , vol.528 , pp. 154-160
    • Macaulay, S.L.1    Grusovin, J.2    Stoichevska, V.3    Ryan, J.M.4    Castelli, L.A.5
  • 48
    • 0035830868 scopus 로고    scopus 로고
    • Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle
    • Khan AH, Thurmond DC, Yang C, Ceresa BP, Sigmund CD, et al. (2001) Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle. J Biol Chem 276: 4063-9.
    • (2001) J Biol Chem , vol.276 , pp. 4063-4069
    • Khan, A.H.1    Thurmond, D.C.2    Yang, C.3    Ceresa, B.P.4    Sigmund, C.D.5
  • 49
    • 4344673217 scopus 로고    scopus 로고
    • Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle
    • Spurlin BA, Park SY, Nevins AK, Kim JK, Thurmond DC, (2004) Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle. Diabetes 53: 2223-31.
    • (2004) Diabetes , vol.53 , pp. 2223-2231
    • Spurlin, B.A.1    Park, S.Y.2    Nevins, A.K.3    Kim, J.K.4    Thurmond, D.C.5


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