메뉴 건너뛰기




Volumn 12, Issue 10, 2010, Pages 1042-1050

Activation of liver X receptors with T0901317 attenuates cardiac hypertrophy in vivo

Author keywords

Hypertrophy; Liver X receptor; Metabolism; Myocytes; Pressure; Remodelling

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; ENDOTHELIN 1; ISOPROTEIN; LIVER X RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; SMALL INTERFERING RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C;

EID: 77957222438     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1093/eurjhf/hfq109     Document Type: Article
Times cited : (37)

References (32)
  • 1
    • 0002537440 scopus 로고    scopus 로고
    • Cardiac hypertrophy: The good, the bad, and the ugly
    • Frey N, Olson EN. Cardiac hypertrophy: the good, the bad, and the ugly. Annu Rev Physiol 2003;65:45-79.
    • (2003) Annu Rev Physiol , vol.65 , pp. 45-79
    • Frey, N.1    Olson, E.N.2
  • 4
    • 0028990133 scopus 로고
    • Interleukin-1 beta induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture
    • Palmer JN, Hartogensis WE, Patten M, Fortuin FD, Long CS. Interleukin-1 beta induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture. J Clin Invest 1995;95:2555-2564.
    • (1995) J Clin Invest , vol.95 , pp. 2555-2564
    • Palmer, J.N.1    Hartogensis, W.E.2    Patten, M.3    Fortuin, F.D.4    Long, C.S.5
  • 5
    • 8644255077 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha induces human atrial myofibroblast proliferation, invasion and MMP-9 secretion: Inhibition by simvastatin
    • Porter KE, Turner NA, O'Regan DJ, Ball SG. Tumor necrosis factor alpha induces human atrial myofibroblast proliferation, invasion and MMP-9 secretion: inhibition by simvastatin. Cardiovasc Res 2004;64:507-515.
    • (2004) Cardiovasc Res , vol.64 , pp. 507-515
    • Porter, K.E.1    Turner, N.A.2    O'Regan, D.J.3    Ball, S.G.4
  • 6
    • 58149305990 scopus 로고    scopus 로고
    • With great power comes great responsibility: Using mouse genetics to study cardiac hypertrophy and failure
    • Molkentin JD, Robbins J. With great power comes great responsibility: using mouse genetics to study cardiac hypertrophy and failure. J Mol Cell Cardiol 2009;46:130-136.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 130-136
    • Molkentin, J.D.1    Robbins, J.2
  • 7
    • 32944473282 scopus 로고    scopus 로고
    • Nuclear receptors in lipid metabolism: Targeting the heart of dyslipidemia
    • Beaven SW, Tontonoz P. Nuclear receptors in lipid metabolism: targeting the heart of dyslipidemia. Annu Rev Med 2006;57:313-329.
    • (2006) Annu Rev Med , vol.57 , pp. 313-329
    • Beaven, S.W.1    Tontonoz, P.2
  • 8
    • 54549096967 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and their agonists for hypertension and heart failure: Are the reagents beneficial or harmful?
    • Chen R, Liang F, Moriya J, Yamakawa J, Takahashi T, Shen L, Kanda T. Peroxisome proliferator-activated receptors (PPARs) and their agonists for hypertension and heart failure: are the reagents beneficial or harmful? Int J Cardiol 2008;130: 131-139.
    • (2008) Int J Cardiol , vol.130 , pp. 131-139
    • Chen, R.1    Liang, F.2    Moriya, J.3    Yamakawa, J.4    Takahashi, T.5    Shen, L.6    Kanda, T.7
  • 9
    • 56249140398 scopus 로고    scopus 로고
    • Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors
    • Hong C, Tontonoz P. Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors. Curr Opin Genet Dev 2008;18:461-467.
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 461-467
    • Hong, C.1    Tontonoz, P.2
  • 13
    • 30844449427 scopus 로고    scopus 로고
    • Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha
    • Chen M, Beaven S, Tontonoz P. Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha. J Lipid Res 2005;46:2570-2579.
    • (2005) J Lipid Res , vol.46 , pp. 2570-2579
    • Chen, M.1    Beaven, S.2    Tontonoz, P.3
  • 15
    • 33846864235 scopus 로고    scopus 로고
    • Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor alpha
    • Van der Veen JN, Havinga R, Bloks VW, Groen AK, Kuipers F. Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor alpha. J Lipid Res 2007;48:337-347.
    • (2007) J Lipid Res , vol.48 , pp. 337-347
    • Van Der Veen, J.N.1    Havinga, R.2    Bloks, V.W.3    Groen, A.K.4    Kuipers, F.5
  • 16
    • 0015302972 scopus 로고
    • Measurement of left ventricular wall thickness and mass by echocardiography
    • Troy BL, Pombo J, Rackley CE. Measurement of left ventricular wall thickness and mass by echocardiography. Circulation 1972;45:602-611.
    • (1972) Circulation , vol.45 , pp. 602-611
    • Troy, B.L.1    Pombo, J.2    Rackley, C.E.3
  • 18
    • 29444443631 scopus 로고    scopus 로고
    • Liver x receptors: Potential novel targets in cardiovascular diseases
    • Bruemmer D, Law RE. Liver x receptors: potential novel targets in cardiovascular diseases. Curr Drug Targets Cardiovasc Haematol Disord 2005;5:533-540.
    • (2005) Curr Drug Targets Cardiovasc Haematol Disord , vol.5 , pp. 533-540
    • Bruemmer, D.1    Law, R.E.2
  • 19
    • 70449706059 scopus 로고    scopus 로고
    • Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-kappaB signalling
    • Wu S, Yin R, Ernest R, Li Y, Zhelyabovska O, Luo J, Yang Y, Yang Q. Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-kappaB signalling. Cardiovasc Res 2009;84:119-126.
    • (2009) Cardiovasc Res , vol.84 , pp. 119-126
    • Wu, S.1    Yin, R.2    Ernest, R.3    Li, Y.4    Zhelyabovska, O.5    Luo, J.6    Yang, Y.7    Yang, Q.8
  • 20
    • 33748555190 scopus 로고    scopus 로고
    • Blood pressure is the major driving force for plaque formation in aortic-constricted ApoE2/2 mice
    • Johansson ME, Wickman A, Skott O, Gan LM, Bergstrom G. Blood pressure is the major driving force for plaque formation in aortic-constricted ApoE2/2 mice. J Hypertens 2006;24:2001-2008.
    • (2006) J Hypertens , vol.24 , pp. 2001-2008
    • Johansson, M.E.1    Wickman, A.2    Skott, O.3    Gan, L.M.4    Bergstrom, G.5
  • 22
    • 34250192234 scopus 로고    scopus 로고
    • GW3965, a synthetic liver X receptor (LXR) agonist, reduces angiotensin II-mediated pressor responses in Sprague-Dawley rats
    • Leik CE, Carson NL, Hennan JK, Basso MD, Liu QY, Crandall DL, Nambi P. GW3965, a synthetic liver X receptor (LXR) agonist, reduces angiotensin II-mediated pressor responses in Sprague-Dawley rats. Br J Pharmacol 2007;151: 450-456.
    • (2007) Br J Pharmacol , vol.151 , pp. 450-456
    • Leik, C.E.1    Carson, N.L.2    Hennan, J.K.3    Basso, M.D.4    Liu, Q.Y.5    Crandall, D.L.6    Nambi, P.7
  • 23
    • 4544269713 scopus 로고    scopus 로고
    • Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: The Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial
    • Devereux RB, Dahlöf B, Gerdts E, Boman K, Nieminen MS, Papademetriou V, Rokkedal J, Harris KE, Edelman JM, Wachtell K. Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial. Circulation 2004;110: 1456-1462.
    • (2004) Circulation , vol.110 , pp. 1456-1462
    • Devereux, R.B.1    Dahlöf, B.2    Gerdts, E.3    Boman, K.4    Nieminen, M.S.5    Papademetriou, V.6    Rokkedal, J.7    Harris, K.E.8    Edelman, J.M.9    Wachtell, K.10
  • 25
    • 33947367803 scopus 로고    scopus 로고
    • Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells
    • Wente W, Brenner MB, Zitzer H, Gromada J, Efanov AM. Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells. Endocrinology 2007;148:1843-1849.
    • (2007) Endocrinology , vol.148 , pp. 1843-1849
    • Wente, W.1    Brenner, M.B.2    Zitzer, H.3    Gromada, J.4    Efanov, A.M.5
  • 31
    • 70350213114 scopus 로고    scopus 로고
    • Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates post-transcriptional TNF-alpha production and p38 MAPK activation in liver macro-phages
    • Wang YY, Dahle MK, Steffensen KR, Reinholt FP, Collins JL, Thiemermann C, Aasen AO, Gustafsson JA, Wang JE. Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates post-transcriptional TNF-alpha production and p38 MAPK activation in liver macro-phages. Shock 2009;32:548-553.
    • (2009) Shock , vol.32 , pp. 548-553
    • Wang, Y.Y.1    Dahle, M.K.2    Steffensen, K.R.3    Reinholt, F.P.4    Collins, J.L.5    Thiemermann, C.6    Aasen, A.O.7    Gustafsson, J.A.8    Wang, J.E.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.