-
1
-
-
0242331221
-
Mechanisms of human DNA repair: an update
-
Christmann M., Tomicic M.T., Roos W.P., Kaina B. Mechanisms of human DNA repair: an update. Toxicology 2003, 193:3-34.
-
(2003)
Toxicology
, vol.193
, pp. 3-34
-
-
Christmann, M.1
Tomicic, M.T.2
Roos, W.P.3
Kaina, B.4
-
2
-
-
0033538461
-
Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'→5' exonucleases
-
Mazur D.J., Perrino F.W. Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'→5' exonucleases. J. Biol. Chem. 1999, 274:19655-19660.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19655-19660
-
-
Mazur, D.J.1
Perrino, F.W.2
-
3
-
-
0035907239
-
Excision of 3' termini by the Trex1 and TREX2 3'→5' exonucleases. Characterization of the recombinant proteins
-
Mazur D.J., Perrino F.W. Excision of 3' termini by the Trex1 and TREX2 3'→5' exonucleases. Characterization of the recombinant proteins. J. Biol. Chem. 2001, 276:17022-17029.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17022-17029
-
-
Mazur, D.J.1
Perrino, F.W.2
-
4
-
-
33746581694
-
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus
-
Crow Y.J., Hayward B.E., Parmar R., Robins P., Leitch A., Ali M., Black D.N., van Bokhoven H., Brunner H.G., Hamel B.C., Corry P.C., Cowan F.M., Frints S.G., Klepper J., Livingston J.H., Lynch S.A., Massey R.F., Meritet J.F., Michaud J.L., Ponsot G., Voit T., Lebon P., Bonthron D.T., Jackson A.P., Barnes D.E., Lindahl T. Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus. Nat. Genet. 2006, 38:917-920.
-
(2006)
Nat. Genet.
, vol.38
, pp. 917-920
-
-
Crow, Y.J.1
Hayward, B.E.2
Parmar, R.3
Robins, P.4
Leitch, A.5
Ali, M.6
Black, D.N.7
van Bokhoven, H.8
Brunner, H.G.9
Hamel, B.C.10
Corry, P.C.11
Cowan, F.M.12
Frints, S.G.13
Klepper, J.14
Livingston, J.H.15
Lynch, S.A.16
Massey, R.F.17
Meritet, J.F.18
Michaud, J.L.19
Ponsot, G.20
Voit, T.21
Lebon, P.22
Bonthron, D.T.23
Jackson, A.P.24
Barnes, D.E.25
Lindahl, T.26
more..
-
5
-
-
34147185679
-
Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome
-
Rice G., Newman W.G., Dean J., Patrick T., Parmar R., Flintoff K., Robins P., Harvey S., Hollis T., O'Hara A., Herrick A.L., Bowden A.P., Perrino F.W., Lindahl T., Barnes D.E., Crow Y.J. Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome. Am. J. Hum. Genet. 2007, 80:811-815.
-
(2007)
Am. J. Hum. Genet.
, vol.80
, pp. 811-815
-
-
Rice, G.1
Newman, W.G.2
Dean, J.3
Patrick, T.4
Parmar, R.5
Flintoff, K.6
Robins, P.7
Harvey, S.8
Hollis, T.9
O'Hara, A.10
Herrick, A.L.11
Bowden, A.P.12
Perrino, F.W.13
Lindahl, T.14
Barnes, D.E.15
Crow, Y.J.16
-
6
-
-
34548334617
-
C-terminal truncations in human 3'-5' DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy
-
Richards A., van den Maagdenberg A.M., Jen J.C., Kavanagh D., Bertram P., Spitzer D., Liszewski M.K., Barilla-Labarca M.L., Terwindt G.M., Kasai Y., McLellan M., Grand M.G., Vanmolkot K.R., de Vries B., Wan J., Kane M.J., Mamsa H., Schafer R., Stam A.H., Haan J., de Jong P.T., Storimans C.W., van Schooneveld M.J., Oosterhuis J.A., Gschwendter A., Dichgans M., Kotschet K.E., Hodgkinson S., Hardy T.A., Delatycki M.B., Hajj-Ali R.A., Kothari P.H., Nelson S.F., Frants R.R., Baloh R.W., Ferrari M.D., Atkinson J.P. C-terminal truncations in human 3'-5' DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy. Nat. Genet. 2007, 39:1068-1070.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1068-1070
-
-
Richards, A.1
van den Maagdenberg, A.M.2
Jen, J.C.3
Kavanagh, D.4
Bertram, P.5
Spitzer, D.6
Liszewski, M.K.7
Barilla-Labarca, M.L.8
Terwindt, G.M.9
Kasai, Y.10
McLellan, M.11
Grand, M.G.12
Vanmolkot, K.R.13
de Vries, B.14
Wan, J.15
Kane, M.J.16
Mamsa, H.17
Schafer, R.18
Stam, A.H.19
Haan, J.20
de Jong, P.T.21
Storimans, C.W.22
van Schooneveld, M.J.23
Oosterhuis, J.A.24
Gschwendter, A.25
Dichgans, M.26
Kotschet, K.E.27
Hodgkinson, S.28
Hardy, T.A.29
Delatycki, M.B.30
Hajj-Ali, R.A.31
Kothari, P.H.32
Nelson, S.F.33
Frants, R.R.34
Baloh, R.W.35
Ferrari, M.D.36
Atkinson, J.P.37
more..
-
7
-
-
34548327158
-
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus
-
Lee-Kirsch M.A., Gong M., Chowdhury D., Senenko L., Engel K., Lee Y.A., de Silva U., Bailey S.L., Witte T., Vyse T.J., Kere J., Pfeiffer C., Harvey S., Wong A., Koskenmies S., Hummel O., Rohde K., Schmidt R.E., Dominiczak A.F., Gahr M., Hollis T., Perrino F.W., Lieberman J., Hubner N. Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nat. Genet. 2007, 39:1065-1067.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1065-1067
-
-
Lee-Kirsch, M.A.1
Gong, M.2
Chowdhury, D.3
Senenko, L.4
Engel, K.5
Lee, Y.A.6
de Silva, U.7
Bailey, S.L.8
Witte, T.9
Vyse, T.J.10
Kere, J.11
Pfeiffer, C.12
Harvey, S.13
Wong, A.14
Koskenmies, S.15
Hummel, O.16
Rohde, K.17
Schmidt, R.E.18
Dominiczak, A.F.19
Gahr, M.20
Hollis, T.21
Perrino, F.W.22
Lieberman, J.23
Hubner, N.24
more..
-
8
-
-
34247842779
-
A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus
-
Lee-Kirsch M.A., Chowdhury D., Harvey S., Gong M., Senenko L., Engel K., Pfeiffer C., Hollis T., Gahr M., Perrino F.W., Lieberman J., Hubner N. A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus. J. Mol. Med. 2007, 85:531-537.
-
(2007)
J. Mol. Med.
, vol.85
, pp. 531-537
-
-
Lee-Kirsch, M.A.1
Chowdhury, D.2
Harvey, S.3
Gong, M.4
Senenko, L.5
Engel, K.6
Pfeiffer, C.7
Hollis, T.8
Gahr, M.9
Perrino, F.W.10
Lieberman, J.11
Hubner, N.12
-
9
-
-
3242672339
-
Gene-targeted mice lacking the Trex1 (DNase III) 3'→5' DNA exonuclease develop inflammatory myocarditis
-
Morita M., Stamp G., Robins P., Dulic A., Rosewell I., Hrivnak G., Daly G., Lindahl T., Barnes D.E. Gene-targeted mice lacking the Trex1 (DNase III) 3'→5' DNA exonuclease develop inflammatory myocarditis. Mol. Cell. Biol. 2004, 24:6719-6727.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 6719-6727
-
-
Morita, M.1
Stamp, G.2
Robins, P.3
Dulic, A.4
Rosewell, I.5
Hrivnak, G.6
Daly, G.7
Lindahl, T.8
Barnes, D.E.9
-
10
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
Stetson D.B., Ko J.S., Heidmann T., Medzhitov R. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 2008, 134:587-598.
-
(2008)
Cell
, vol.134
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
Medzhitov, R.4
-
11
-
-
80052752626
-
Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome
-
Fye J.M., Orebaugh C.D., Coffin S.R., Hollis T., Perrino F.W. Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome. J. Biol. Chem. 2011, 286:32373-32382.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 32373-32382
-
-
Fye, J.M.1
Orebaugh, C.D.2
Coffin, S.R.3
Hollis, T.4
Perrino, F.W.5
-
12
-
-
57649134251
-
The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease
-
Lehtinen D.A., Harvey S., Mulcahy M.J., Hollis T., Perrino F.W. The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease. J. Biol. Chem. 2008, 283:31649-31656.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 31649-31656
-
-
Lehtinen, D.A.1
Harvey, S.2
Mulcahy, M.J.3
Hollis, T.4
Perrino, F.W.5
-
13
-
-
33745501366
-
The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death
-
Chowdhury D., Beresford P.J., Zhu P., Zhang D., Sung J.S., Demple B., Perrino F.W., Lieberman J. The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death. Mol. Cell 2006, 23:133-142.
-
(2006)
Mol. Cell
, vol.23
, pp. 133-142
-
-
Chowdhury, D.1
Beresford, P.J.2
Zhu, P.3
Zhang, D.4
Sung, J.S.5
Demple, B.6
Perrino, F.W.7
Lieberman, J.8
-
14
-
-
63449120803
-
The SET complex acts as a barrier to autointegration of HIV-1
-
Yan N., Cherepanov P., Daigle J.E., Engelman A., Lieberman J. The SET complex acts as a barrier to autointegration of HIV-1. PLoS Pathog. 2009, 5:e1000327.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Yan, N.1
Cherepanov, P.2
Daigle, J.E.3
Engelman, A.4
Lieberman, J.5
-
15
-
-
77958114725
-
The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
-
Yan N., Regalado-Magdos A.D., Stiggelbout B., Lee-Kirsch M.A., Lieberman J. The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1. Nat. Immunol. 2011, 11:1005-1013.
-
(2011)
Nat. Immunol.
, vol.11
, pp. 1005-1013
-
-
Yan, N.1
Regalado-Magdos, A.D.2
Stiggelbout, B.3
Lee-Kirsch, M.A.4
Lieberman, J.5
-
16
-
-
36248988008
-
Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease
-
Yang Y.G., Lindahl T., Barnes D.E. Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease. Cell 2007, 131:873-886.
-
(2007)
Cell
, vol.131
, pp. 873-886
-
-
Yang, Y.G.1
Lindahl, T.2
Barnes, D.E.3
-
17
-
-
78049369870
-
Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage
-
Christmann M., Tomicic M.T., Aasland D., Berdelle N., Kaina B. Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage. Nucleic Acids Res. 2010, 38:6418-6432.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 6418-6432
-
-
Christmann, M.1
Tomicic, M.T.2
Aasland, D.3
Berdelle, N.4
Kaina, B.5
-
18
-
-
58749097764
-
Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53
-
Naumann S.C., Roos W.P., Jost E., Belohlavek C., Lennerz V., Schmidt C.W., Christmann M., Kaina B. Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53. Br. J. Cancer 2009, 100:322-333.
-
(2009)
Br. J. Cancer
, vol.100
, pp. 322-333
-
-
Naumann, S.C.1
Roos, W.P.2
Jost, E.3
Belohlavek, C.4
Lennerz, V.5
Schmidt, C.W.6
Christmann, M.7
Kaina, B.8
-
19
-
-
0344441926
-
CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death
-
Wischhusen J., Naumann U., Ohgaki H., Rastinejad F., Weller M. CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death. Oncogene 2003, 22:8233-8245.
-
(2003)
Oncogene
, vol.22
, pp. 8233-8245
-
-
Wischhusen, J.1
Naumann, U.2
Ohgaki, H.3
Rastinejad, F.4
Weller, M.5
-
20
-
-
0034680776
-
Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents
-
Christmann M., Kaina B. Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents. J. Biol. Chem. 2000, 275:36256-36262.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36256-36262
-
-
Christmann, M.1
Kaina, B.2
-
21
-
-
0037194665
-
Comparative analysis of DNA breakage, chromosomal aberrations and apoptosis induced by the anti-herpes purine nucleoside analogues aciclovir, ganciclovir and penciclovir
-
Tomicic M.T., Bey E., Wutzler P., Thust R., Kaina B. Comparative analysis of DNA breakage, chromosomal aberrations and apoptosis induced by the anti-herpes purine nucleoside analogues aciclovir, ganciclovir and penciclovir. Mutat. Res. 2002, 505:1-11.
-
(2002)
Mutat. Res.
, vol.505
, pp. 1-11
-
-
Tomicic, M.T.1
Bey, E.2
Wutzler, P.3
Thust, R.4
Kaina, B.5
-
22
-
-
0037310208
-
Apoptosis induced by (E)-5-(2-bromovinyl)-2'-deoxyuridine in varicella zoster virus thymidine kinase-expressing cells is driven by activation of c-Jun/activator protein-1 and Fas ligand/caspase-8
-
Tomicic M.T., Friedrichs C., Christmann M., Wutzler P., Thust R., Kaina B. Apoptosis induced by (E)-5-(2-bromovinyl)-2'-deoxyuridine in varicella zoster virus thymidine kinase-expressing cells is driven by activation of c-Jun/activator protein-1 and Fas ligand/caspase-8. Mol. Pharmacol. 2003, 63:439-449.
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 439-449
-
-
Tomicic, M.T.1
Friedrichs, C.2
Christmann, M.3
Wutzler, P.4
Thust, R.5
Kaina, B.6
-
23
-
-
79958773010
-
Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity
-
Tomicic M.T., Reischmann P., Rasenberger B., Meise R., Kaina B., Christmann M. Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity. Cell. Mol. Life Sci. 2011, 68:1785-1798.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 1785-1798
-
-
Tomicic, M.T.1
Reischmann, P.2
Rasenberger, B.3
Meise, R.4
Kaina, B.5
Christmann, M.6
-
24
-
-
27544468372
-
The Fos family of transcription factors and their role in tumourigenesis
-
Milde-Langosch K. The Fos family of transcription factors and their role in tumourigenesis. Eur. J. Cancer 2005, 41:2449-2461.
-
(2005)
Eur. J. Cancer
, vol.41
, pp. 2449-2461
-
-
Milde-Langosch, K.1
-
25
-
-
73349090951
-
The transcription factor Fos: a Janus-type regulator in health and disease
-
Durchdewald M., Angel P., Hess J. The transcription factor Fos: a Janus-type regulator in health and disease. Histol. Histopathol. 2009, 24:1451-1461.
-
(2009)
Histol. Histopathol.
, vol.24
, pp. 1451-1461
-
-
Durchdewald, M.1
Angel, P.2
Hess, J.3
-
26
-
-
33846532954
-
Focus on fotemustine
-
De Rossi A., Rossi L., Laudisi A., Sini V., Toppo L., Marchesi F., Tortorelli G., Leti M., Turriziani M., Aquino A., Bonmassar E., De Vecchis L., Torino F. Focus on fotemustine. J. Exp. Clin. Cancer Res. 2006, 25:461-468.
-
(2006)
J. Exp. Clin. Cancer Res.
, vol.25
, pp. 461-468
-
-
De Rossi, A.1
Rossi, L.2
Laudisi, A.3
Sini, V.4
Toppo, L.5
Marchesi, F.6
Tortorelli, G.7
Leti, M.8
Turriziani, M.9
Aquino, A.10
Bonmassar, E.11
De Vecchis, L.12
Torino, F.13
-
27
-
-
79951836166
-
Characterization of Trex1 induction by IFN-gamma in murine macrophages
-
Serra M., Forcales S.V., Pereira-Lopes S., Lloberas J., Celada A. Characterization of Trex1 induction by IFN-gamma in murine macrophages. J. Immunol. 2011, 186:2299-2308.
-
(2011)
J. Immunol.
, vol.186
, pp. 2299-2308
-
-
Serra, M.1
Forcales, S.V.2
Pereira-Lopes, S.3
Lloberas, J.4
Celada, A.5
-
28
-
-
70149107812
-
TREX1 acts in degrading damaged DNA from drug-treated tumor cells
-
Wang C.J., Lam W., Bussom S., Chang H.M., Cheng Y.C. TREX1 acts in degrading damaged DNA from drug-treated tumor cells. DNA Repair (Amst) 2009, 8:1179-1189.
-
(2009)
DNA Repair (Amst)
, vol.8
, pp. 1179-1189
-
-
Wang, C.J.1
Lam, W.2
Bussom, S.3
Chang, H.M.4
Cheng, Y.C.5
-
29
-
-
0034667383
-
Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent
-
Ochs K., Kaina B. Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent. Cancer Res. 2000, 60:5815-5824.
-
(2000)
Cancer Res.
, vol.60
, pp. 5815-5824
-
-
Ochs, K.1
Kaina, B.2
-
30
-
-
84876093576
-
DNA damage-induced apoptosis: from specific DNA lesions to the DNA damage response and apoptosis
-
Roos W.P., Kaina B. DNA damage-induced apoptosis: from specific DNA lesions to the DNA damage response and apoptosis. Cancer Lett. 2013.
-
(2013)
Cancer Lett.
-
-
Roos, W.P.1
Kaina, B.2
-
31
-
-
0025294971
-
Ionizing radiation regulates expression of the c-Jun protooncogene
-
Sherman M.L., Datta R., Hallahan D.E., Weichselbaum R.R., Kufe D.W. Ionizing radiation regulates expression of the c-Jun protooncogene. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:5663-5666.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 5663-5666
-
-
Sherman, M.L.1
Datta, R.2
Hallahan, D.E.3
Weichselbaum, R.R.4
Kufe, D.W.5
-
32
-
-
0029856557
-
Three distinct signalling responses by murine fibroblasts to genotoxic stress
-
Liu Z.G., Baskaran R., Lea-Chou E.T., Wood L.D., Chen Y., Karin M., Wang J.Y. Three distinct signalling responses by murine fibroblasts to genotoxic stress. Nature 1996, 384:273-276.
-
(1996)
Nature
, vol.384
, pp. 273-276
-
-
Liu, Z.G.1
Baskaran, R.2
Lea-Chou, E.T.3
Wood, L.D.4
Chen, Y.5
Karin, M.6
Wang, J.Y.7
-
33
-
-
0029972260
-
Induction of c-fos, c-Jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability
-
Dosch J., Kaina B. Induction of c-fos, c-Jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability. Oncogene 1996, 13:1927-1935.
-
(1996)
Oncogene
, vol.13
, pp. 1927-1935
-
-
Dosch, J.1
Kaina, B.2
-
34
-
-
25444453168
-
Topotecan-triggered degradation of topoisomerase I is p53-dependent and impacts cell survival
-
Tomicic M.T., Christmann M., Kaina B. Topotecan-triggered degradation of topoisomerase I is p53-dependent and impacts cell survival. Cancer Res. 2005, 65:8920-8926.
-
(2005)
Cancer Res.
, vol.65
, pp. 8920-8926
-
-
Tomicic, M.T.1
Christmann, M.2
Kaina, B.3
-
35
-
-
73949110695
-
Topotecan triggers apoptosis in p53-deficient cells by forcing degradation of XIAP and survivin thereby activating caspase-3-mediated Bid cleavage
-
Tomicic M.T., Christmann M., Kaina B. Topotecan triggers apoptosis in p53-deficient cells by forcing degradation of XIAP and survivin thereby activating caspase-3-mediated Bid cleavage. J. Pharmacol. Exp. Ther. 2010, 332:316-325.
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, pp. 316-325
-
-
Tomicic, M.T.1
Christmann, M.2
Kaina, B.3
-
36
-
-
84867390244
-
Topoisomerase degradation, DSB repair, p53 and IAPs in cancer cell resistance to camptothecin-like topoisomerase I inhibitors
-
Tomicic M.T., Kaina B. Topoisomerase degradation, DSB repair, p53 and IAPs in cancer cell resistance to camptothecin-like topoisomerase I inhibitors. Biochim. Biophys. Acta 2012, 1835:11-27.
-
(2012)
Biochim. Biophys. Acta
, vol.1835
, pp. 11-27
-
-
Tomicic, M.T.1
Kaina, B.2
-
37
-
-
0036154027
-
Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamster cells
-
Dunkern T.R., Kaina B. Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamster cells. Mol. Biol. Cell 2002, 13:348-361.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 348-361
-
-
Dunkern, T.R.1
Kaina, B.2
-
38
-
-
42749083720
-
Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling
-
Goldstein M., Roos W.P., Kaina B. Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling. Toxicol. Appl. Pharmacol. 2008, 229:20-32.
-
(2008)
Toxicol. Appl. Pharmacol.
, vol.229
, pp. 20-32
-
-
Goldstein, M.1
Roos, W.P.2
Kaina, B.3
-
39
-
-
84861706181
-
The chloroethylating anticancer drug ACNU induces FRA1 that is involved in drug resistance of glioma cells
-
Meise R., Tomicic M.T., Kaina B., Christmann M. The chloroethylating anticancer drug ACNU induces FRA1 that is involved in drug resistance of glioma cells. Biochim. Biophys. Acta 2012, 1823:1199-1207.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 1199-1207
-
-
Meise, R.1
Tomicic, M.T.2
Kaina, B.3
Christmann, M.4
-
40
-
-
33646058609
-
Isolation of human Dna2 endonuclease and characterization of its enzymatic properties
-
Kim J.H., Kim H.D., Ryu G.H., Kim D.H., Hurwitz J., Seo Y.S. Isolation of human Dna2 endonuclease and characterization of its enzymatic properties. Nucleic Acids Res. 2006, 34:1854-1864.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 1854-1864
-
-
Kim, J.H.1
Kim, H.D.2
Ryu, G.H.3
Kim, D.H.4
Hurwitz, J.5
Seo, Y.S.6
-
42
-
-
0031054051
-
Enzymes and reactions at the eukaryotic DNA replication fork
-
Bambara R.A., Murante R.S., Henricksen L.A. Enzymes and reactions at the eukaryotic DNA replication fork. J. Biol. Chem. 1997, 272:4647-4650.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4647-4650
-
-
Bambara, R.A.1
Murante, R.S.2
Henricksen, L.A.3
-
43
-
-
33746522835
-
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection
-
Crow Y.J., Leitch A., Hayward B.E., Garner A., Parmar R., Griffith E., Ali M., Semple C., Aicardi J., Babul-Hirji R., Baumann C., Baxter P., Bertini E., Chandler K.E., Chitayat D., Cau D., Dery C., Fazzi E., Goizet C., King M.D., Klepper J., Lacombe D., Lanzi G., Lyall H., Martinez-Frias M.L., Mathieu M., McKeown C., Monier A., Oade Y., Quarrell O.W., Rittey C.D., Rogers R.C., Sanchis A., Stephenson J.B., Tacke U., Till M., Tolmie J.L., Tomlin P., Voit T., Weschke B., Woods C.G., Lebon P., Bonthron D.T., Ponting C.P., Jackson A.P. Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection. Nat. Genet. 2006, 38:910-916.
-
(2006)
Nat. Genet.
, vol.38
, pp. 910-916
-
-
Crow, Y.J.1
Leitch, A.2
Hayward, B.E.3
Garner, A.4
Parmar, R.5
Griffith, E.6
Ali, M.7
Semple, C.8
Aicardi, J.9
Babul-Hirji, R.10
Baumann, C.11
Baxter, P.12
Bertini, E.13
Chandler, K.E.14
Chitayat, D.15
Cau, D.16
Dery, C.17
Fazzi, E.18
Goizet, C.19
King, M.D.20
Klepper, J.21
Lacombe, D.22
Lanzi, G.23
Lyall, H.24
Martinez-Frias, M.L.25
Mathieu, M.26
McKeown, C.27
Monier, A.28
Oade, Y.29
Quarrell, O.W.30
Rittey, C.D.31
Rogers, R.C.32
Sanchis, A.33
Stephenson, J.B.34
Tacke, U.35
Till, M.36
Tolmie, J.L.37
Tomlin, P.38
Voit, T.39
Weschke, B.40
Woods, C.G.41
Lebon, P.42
Bonthron, D.T.43
Ponting, C.P.44
Jackson, A.P.45
more..
-
44
-
-
0033756041
-
The absence of ribonuclease H1 or H2 alters the sensitivity of Saccharomyces cerevisiae to hydroxyurea, caffeine and ethyl methanesulphonate: implications for roles of RNases H in DNA replication and repair
-
Arudchandran A., Cerritelli S., Narimatsu S., Itaya M., Shin D.Y., Shimada Y., Crouch R.J. The absence of ribonuclease H1 or H2 alters the sensitivity of Saccharomyces cerevisiae to hydroxyurea, caffeine and ethyl methanesulphonate: implications for roles of RNases H in DNA replication and repair. Genes Cells 2000, 5:789-802.
-
(2000)
Genes Cells
, vol.5
, pp. 789-802
-
-
Arudchandran, A.1
Cerritelli, S.2
Narimatsu, S.3
Itaya, M.4
Shin, D.Y.5
Shimada, Y.6
Crouch, R.J.7
-
45
-
-
0033512305
-
Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease
-
Qiu J., Qian Y., Frank P., Wintersberger U., Shen B. Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol. Cell. Biol. 1999, 19:8361-8371.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8361-8371
-
-
Qiu, J.1
Qian, Y.2
Frank, P.3
Wintersberger, U.4
Shen, B.5
-
46
-
-
84861578543
-
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development
-
Reijns M.A., Rabe B., Rigby R.E., Mill P., Astell K.R., Lettice L.A., Boyle S., Leitch A., Keighren M., Kilanowski F., Devenney P.S., Sexton D., Grimes G., Holt I.J., Hill R.E., Taylor M.S., Lawson K.A., Dorin J.R., Jackson A.P. Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development. Cell 2012, 149:1008-1022.
-
(2012)
Cell
, vol.149
, pp. 1008-1022
-
-
Reijns, M.A.1
Rabe, B.2
Rigby, R.E.3
Mill, P.4
Astell, K.R.5
Lettice, L.A.6
Boyle, S.7
Leitch, A.8
Keighren, M.9
Kilanowski, F.10
Devenney, P.S.11
Sexton, D.12
Grimes, G.13
Holt, I.J.14
Hill, R.E.15
Taylor, M.S.16
Lawson, K.A.17
Dorin, J.R.18
Jackson, A.P.19
-
47
-
-
84855352447
-
Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease
-
Bailey S.L., Harvey S., Perrino F.W., Hollis T. Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease. DNA Repair (Amst) 2012, 11:65-73.
-
(2012)
DNA Repair (Amst)
, vol.11
, pp. 65-73
-
-
Bailey, S.L.1
Harvey, S.2
Perrino, F.W.3
Hollis, T.4
-
48
-
-
81155154298
-
The TREX1 exonuclease R114H mutation in Aicardi-Goutieres syndrome and lupus reveals dimeric structure requirements for DNA degradation activity
-
Orebaugh C.D., Fye J.M., Harvey S., Hollis T., Perrino F.W. The TREX1 exonuclease R114H mutation in Aicardi-Goutieres syndrome and lupus reveals dimeric structure requirements for DNA degradation activity. J. Biol. Chem. 2011, 286:40246-40254.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 40246-40254
-
-
Orebaugh, C.D.1
Fye, J.M.2
Harvey, S.3
Hollis, T.4
Perrino, F.W.5
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