The absence of ribonuclease H1 or H2 alters the sensitivity of Saccharomyces cerevisiae to hydroxyurea, caffeine and ethyl methanesulphonate: Implications for roles of RNases H in DNA replication and repair

Genes to Cells

Volumn 5, Issue 10, 2000, Pages 789-802

  Arudchandran, A ^a   Cerritelli, S M ^a   Narimatsu, S K ^a   Itaya, M ^a   Shin, D Y ^a   Shimada, Y ^a   Crouch, R J ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; DNA; HYDROXYUREA; MESYLIC ACID ETHYL ESTER; RIBONUCLEASE H;

ANTIFUNGAL ACTIVITY; ARTICLE; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA RNA HYBRIDIZATION; DNA SYNTHESIS; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME DEFICIENCY; FUNGUS GROWTH; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

CAFFEINE; CELL CYCLE; CELL NUCLEUS; DNA REPAIR; DNA REPLICATION; DNA, FUNGAL; ETHYL METHANESULFONATE; GENE DELETION; GENES, FUNGAL; HYDROXYUREA; NUCLEIC ACID SYNTHESIS INHIBITORS; PHENOTYPE; RECOMBINANT FUSION PROTEINS; RIBONUCLEASE H, CALF THYMUS; SACCHAROMYCES CEREVISIAE;

ESCHERICHIA COLI; EUKARYOTA; FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0033756041     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.2000.00373.x     Document Type: Article

References (55)

1. The SAD1/RAD53 protein-kinase controls multiple checkpoints and DNA damage-induced transcription in yeast
2. Mechanisms that help the yeast-cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins
3. Enzymes and reactions at the eukaryotic DNA replication fork
4. Caffeine-resistance in S. pombe: Mutations in three novel caf genes increase caffeine tolerance and affect radiation sensitivity, fertility, and cell cycle
5. Purification, subunit structure, and seriological analysis of calf thymus ribonuclease H-I
6. Distinct ribonuclease H activities in calf thymus
7. Ribonuclease H levels during the response of bovine lymphocytes to concanavalin A
8. Isolation and mapping of a mutation in Escherichia coli with altered levels of ribonuclease H
9. RNase H of oocytes from the South-African clawed toad Xenopus laevis
10. Characterization and subcellular localization of ribonuclease H activities from Xenopus laevis oocytes
11. The non-RNase H domain of Saccharomyces cerevisiae RNase H1 binds double-stranded RNA: Magnesium modulates the switch between double-stranded RNA binding and RNase H activity
12. Cloning, expression, and mapping of ribonucleases H of human and mouse related to bacterial RNase HI
13. A common 40 amino acid motif in eukaryotic RNases H1 and caulimovirus ORF VI proteins binds to duplex RNAs
14. Roles of ribonuclease H in reverse transcription
15. A genome-wide transcriptional analysis of the mitotic cell cycle
16. A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth
17. Ribonuclease H: From discovery to 3D structure
18. RNases H of S. cerevisiae, S. pombe, C. fasciculata, and N. crassa
19. Ribonucleases H
20. Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
21. Ribonuclease H from K562 human erythroleukemia cells: Purification, characterization, and substrate specificity
22. Substrate specificity of human RNase H1 and its role in excision repair of ribose residues misincorporated in DNA
23. Purification of Saccharomyces cerevisiae RNase H(70) and identification of the corresponding gene
24. Cloning, subcellular localization and functional expression of human RNase HII
25. Yeast RNase H(35) is the counterpart of the mammalian RNase HI, and is evolutionarily related to prokaryotic RNase HII
26. Isolation and characterization of two enzymatic activities from chick embryos which degrade double-stranded RNA
27. Ribonuclease H renaturation gel assay using a fluorescent-labeled substrate
28. Ribonuclease H. An enzyme degrading the RNA moiety of DNA-RNA hybrids
29. HOP1 - A yeast meiotic pairing gene
30. Ribonucleases H
31. RNase H of retroviral reverse transcriptase
32. Isolation and characterization of a second RNase H (RNase HII) of Escherichia coli K12 encoded by the rnhB gene
33. Selective cloning of genes encoding RNase H from Salmonella typhimurium, Saccharomyces cerevisiae and Escherchia coli rnh mutants
34. Isolation of RNase H genes that are essential for growth of Bacillus subtilis 168
35. Transformation of intact yeast cells treated with alkali cations
36. Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication
37. Physiological functions of E. coli RNase HI
38. G2/M checkpoint genes of Saccharomyces cerevisiae: Further evidence for roles in DNA replication and/or repair
39. Isolation of two genes that affect mitotic chromosome transmission in S. cerevisiae
40. Synchronous cell growth occurs upon synchronizing the two regulatory steps of the Saccharomyces cerevisiae cell cycle
41. Junction ribonuclease: An activity in Okazaki fragment processing
42. 2+- dependent RNase HIII from Bacillus subtilis: Classification of RNases H into three families
43. Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease
44. Cloning genes by complementation in yeast
45. Creation and removal of embedded ribonucleotides in chromosomal DNA during mammalian Okazaki fragment processing
46. A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication
47. Analysis of chromosome segregation in Saccharomyces cerevisiae
48. Regulation of DNA-replication origins during cell-cycle progression
49. Detection of specific sequences among DNA fragments separated by gel electrophoresis
50. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization
51. Effect of DNA lesions on transcription elongation
52. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
53. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
54. Properties of cloned and expressed human RNase H1