Ca2+-dependent large conductance K+ currents in thalamocortical relay neurons of different rat strains

Pflugers Archiv European Journal of Physiology

Volumn 465, Issue 4, 2013, Pages 469-480

  Ehling, Petra ^a   Cerina, Manuela ^a   Meuth, Patrick ^a   Kanyshkova, Tatyana ^a   Bista, Pawan ^a   Coulon, Philippe ^a   Meuth, Sven G ^a   Pape, Hans Christian ^a   Budde, Thomas ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Absence epilepsy; BKCa channels; Computer modelling; Spike frequency adaptation; Thalamic firing modes; WAG Rij rat

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CALCIUM ACTIVATED POTASSIUM CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHANNEL GATING; CHILDHOOD ABSENCE EPILEPSY; COMPUTER MODEL; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; INTERNEURON; LATERAL GENICULATE BODY; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RAT; THALAMUS;

ACTION POTENTIALS; ADAPTATION, PHYSIOLOGICAL; ANIMALS; CALCIUM; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; EPILEPSY, ABSENCE; INTERNEURONS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MODELS, NEUROLOGICAL; RATS; RATS, INBRED STRAINS; RECEPTORS, ADRENERGIC, BETA-2; THALAMUS;

EID: 84877799457     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-012-1188-6     Document Type: Article

References (58)

1. +-current by intracellular cAMP in rat thalamocortical relay neurons. Thalamus Relat Syst 1:157-167
2. Bista P, Meuth S, Kanyshkova T, Cerina M, Pawlowski M, Ehling P, Landgraf P, Borsotto M, Heurteaux C, Pape H-C, Baukrowitz T, Budde T (2012) Identification of the muscarinic pathway underlying cessation of sleep-related burst activity in rat thalamocortical relay neurons. Pflügers Archiv Eur J Physiol 463(1):89-102. doi: 10.1007/s00424-011-1056-9
3. Blumenfeld H, Klein J, Schridde U, Vestal M, Rice T, Khera D, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal R, Englot D, Motelow J, Nersesyan H, Waxman S, Levin A (2008) Early treatment suppresses the development of spike-wave epilepsy in a rat model. Epilepsia 49(3):400-409
4. Broicher T, Kanyshkova T, Landgraf P, Rankovic V, Meuth P, Meuth S, Pape H-C, Budde T (2007) Specific expression of low-voltage-activated calcium channel isoforms and splice variants in thalamic local circuit interneurons. Mol Cell Neurosci 36(2):132-145
5. Broicher T, Kanyshkova T, Meuth P, Pape H-C, Budde T (2008) Correlation of T-channel coding gene expression, IT, and the low threshold Ca2+ spike in the thalamus of a rat model of absence epilepsy. Mol Cell Neurosci 39(3):384-399. doi: 10.1016/j.mcn.2008.07.012
6. 2+ channel antagonist on thalamic relay and local circuit interneurons in a rat model of absence epilepsy. Neuropharmacology 53(3):431-446
7. 2+ of the hyperpolarization-activated cation current in rat thalamic neurones. J Physiol 503(Pt 1):79-85
8. Budde T, Caputi L, Kanyshkova T, Staak R, Abrahamczik C, Munsch T, Pape H-C (2005) Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy. J Neurosci Off J Soc Neurosci 25(43):9871-9882
9. Budde T, Mager R, Pape H-C (1992) Different types of potassium outward current in relay neurons acutely isolated from the rat lateral geniculate nucleus. Eur J Neurosci 4(8):708-722
10. 2+ release supports the relay mode of activity in thalamocortical cells. Neuron 26(2):483-492
11. Chen L, Tian L, MacDonald S, McClafferty H, Hammond M, Huibant J-M, Ruth P, Knaus H-G, Shipston M (2005) Functionally diverse complement of large conductance calcium- and voltage-activated potassium channel (BK) alpha-subunits generated from a single site of splicing. J Biol Chem 280(39):33599-33609
12. Chen Y, Lu J, Pan H, Zhang Y, Wu H, Xu K, Liu X, Jiang Y, Bao X, Yao Z, Ding K, Lo W, Qiang B, Chan P, Shen Y, Wu X (2003) Association between genetic variation of CACNA1H and childhood absence epilepsy. Ann Neurol 54(2):239-243
13. Coenen A, Van Luijtelaar E (2003) Genetic animal models for absence epilepsy: a review of the WAG/Rij strain of rats. Behav Genet 33(6):635-655
14. Coulon P, Budde T, Pape H-C (2012) The sleep relay - the role of the thalamus in central and decentral sleep regulation. Pflügers Archiv Eur J Physiol 463(1):53-71
15. Danober L, Deransart C, Depaulis A, Vergnes M, Marescaux C (1998) Pathophysiological mechanisms of genetic absence epilepsy in the rat. Prog Neurobiol 55(1):27-57
16. Depaulis A, van Luijtelaar G (2006) Genetic models of absence epilepsy in the rat. In: Pitkänen A, Schwrtzkroin P, Moshé S (eds) Models of seizures and epilepsy. Elsevier, San Diego
17. Destexhe A, Bal T, McCormick D, Sejnowski T (1996) Ionic mechanisms underlying synchronized oscillations and propagating waves in a model of ferret thalamic slices. J Neurophysiol 76(3):2049-2070
18. Eichhorn B, Dobrev D (2007) Vascular large conductance calcium-activated potassium channels: functional role and therapeutic potential. Naunyn Schmiedeberg's Arch Pharmacol 376(3):145-155
19. Ghatta S, Nimmagadda D, Xu X, O'Rourke S (2006) Large-conductance, calcium-activated potassium channels: structural and functional implications. Pharmacol Ther 110(1):103-116
20. Gribkoff VK, Starrett JE, Dworetzky SI (2001) Maxi-K potassium channels: form, function, and modulation of a class of endogenous regulators of intracellular calcium. Neuroscientist 7(2):166-177
21. Gu N, Vervaeke K, Storm J (2007) BK potassium channels facilitate high-frequency firing and cause early spike frequency adaptation in rat CA1 hippocampal pyramidal cells. J Physiol 580(Pt.3):859-882
22. Guyon A, Vergnes M, Leresche N (1993) Thalamic low threshold calcium current in a genetic model of absence epilepsy. NeuroReport 4(11):1231-1234
23. Hall S, Armstrong D (2000) Conditional and unconditional inhibition of calcium-activated potassium channels by reversible protein phosphorylation. J Biol Chem 275(6):3749-3754
24. Hines M, Carnevale N (1997) The NEURON simulation environment. Neural Comput 9(6):1179-1209
25. Houweling A, Sejnowski T (1997) MyFirstNeuron. Oxford University Press, New York
26. Huguenard J, Prince D (1991) Slow inactivation of a TEA-sensitive K current in acutely isolated rat thalamic relay neurons. J Neurophysiol 66(4):1316-1328
27. Inoue M, Peeters B, van Luijtelaar E, Vossen J, Coenen A (1990) Spontaneous occurrence of spike-wave discharges in five inbred strains of rats. Physiol Behav 48(1):199-201
28. Kanyshkova T, Meuth P, Bista P, Liu Z, Ehling P, Caputi L, Doengi M, Chetkovich D, Pape H-C, Budde T (2012) Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains. Neurobiol Dis 45(1):450-461. doi: 10.1016/j.nbd.2011.08.032
29. + channels in human myometrium during pregnancy and labour. Proc Biol Sci R Soc 251(1330):9-15
30. Kuisle M, Wanaverbecq N, Brewster A, Frère S, Pinault D, Baram T, Lüthi A (2006) Functional stabilization of weakened thalamic pacemaker channel regulation in rat absence epilepsy. J Physiol 575(Pt 1):83-100
31. Leresche N, Parri H, Erdemli G, Guyon A, Turner J, Williams S, Asprodini E, Crunelli V (1998) On the action of the anti-absence drug ethosuximide in the rat and cat thalamus. J Neurosci: Off J Soc Neurosci 18(13):4842-4853
32. MacDonald S, Ruth P, Knaus H-G, Shipston M (2006) Increased large conductance calcium-activated potassium (BK) channel expression accompanied by STREX variant downregulation in the developing mouse CNS. BMC Dev Biol 6:37
33. Mahmoud S, McCobb D (2004) Regulation of Slo potassium channel alternative splicing in the pituitary by gonadal testosterone. J Neuroendocrinol 16(3):237-243
34. McCormick D (1992) Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity. Prog Neurobiol 39(4):337-388
35. McCormick D, Huguenard J (1992) A model of the electrophysiological properties of thalamocortical relay neurons. J Neurophysiol 68(4):1384-1400
36. McCormick D, Pape H (1990) Properties of a hyperpolarization-activated cation current and its role in rhythmic oscillation in thalamic relay neurones. J Physiol 431:291-318
37. McCrea K, Hill S (1993) Salmeterol, a long-acting beta 2-adrenoceptor agonist mediating cyclic AMP accumulation in a neuronal cell line. Br J Pharmacol 110(2):619-626
38. Meuth S, Budde T, Kanyshkova T, Broicher T, Munsch T, Pape H-C (2003) Contribution of TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons. J Neurosc Off J Soc Neurosci 23(16):6460-6469
39. Meuth S, Kanyshkova T, Meuth P, Landgraf P, Munsch T, Ludwig A, Hofmann F, Pape H-C, Budde T (2006) Membrane resting potential of thalamocortical relay neurons is shaped by the interaction among TASK3 and HCN2 channels. J Neurophysiol 96(3):1517-1529. doi: 10.1152/jn.01212.2005
40. 2+ currents in rat thalamocortical relay neurons by activity and phosphorylation. Eur J Neurosci 15(10):1603-1614. doi: 10.1046/j.1460-9568.2002.01999.x
41. Pape H (1996) Queer current and pacemaker: the hyperpolarization- activated cation current in neurons. Annu Rev Physiol 58:299-327
42. 2+ channels via β-adrenergic signaling in thalamocortical relay neurons. PLoS One 6(12). doi: 10.1371/journal.pone.0027474
43. Rogawski M, Löscher W (2004) The neurobiology of antiepileptic drugs. Nat Rev Neurosci 5(7):553-564
44. Sanchez M, McManus O (1996) Paxilline inhibition of the alpha-subunit of the high-conductance calcium-activated potassium channel. Neuropharmacology 35(7):963-968
45. Saucerman J, McCulloch A (2006) Cardiac beta-adrenergic signaling: from subcellular microdomains to heart failure. Ann N Y Acad Sci 1080:348-361. doi: 10.1196/annals.1380.026
46. Schridde U, Strauss U, Bräuer A, van Luijtelaar G (2006) Environmental manipulations early in development alter seizure activity, Ih and HCN1 protein expression later in life. Eur J Neurosci 23(12):3346-3358
47. Schubert R, Nelson M (2001) Protein kinases: tuners of the BKCa channel in smooth muscle. Trends Pharmacol Sci 22(10):505-512
48. + channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells. J Physiol 521(Pt 1):135-146
49. Sherman S, Guillery R (2006) Exploring the thalamus and its role in cortical function, 2nd edn. MIT, Cambridge
50. Shipston M, Armstrong D (1996) Activation of protein kinase C inhibits calcium-activated potassium channels in rat pituitary tumour cells. J Physiol 493(Pt 3):665-672
51. Staak R, Pape H (2001) Contribution of GABA(A) and GABA(B) receptors to thalamic neuronal activity during spontaneous absence seizures in rats. J Neurosci Off J Soc Neurosci 21(4):1378-1384
52. Steriade M (1997) Synchronized activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance. Cereb Cortex (NY 1991) 7(6):583-604
53. Steriade M, Llinás R (1988) The functional states of the thalamus and the associated neuronal interplay. Physiol Rev 68(3):649-742
54. Tian L, Coghill L, McClafferty H, MacDonald S, Antoni F, Ruth P, Knaus H-G, Shipston M (2004) Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase. Proc Natl Acad Sci U S A 101(32):11897-11902
55. Tian L, Duncan R, Hammond M, Coghill L, Wen H, Rusinova R, Clark A, Levitan I, Shipston M (2001) Alternative splicing switches potassium channel sensitivity to protein phosphorylation. J Biol Chem 276(11):7717-7720
56. Tóth T, Crunelli V (1997) Simulation of intermittent action potential firing in thalamocortical neurons. Neuroreport 8(13):2889-2892
57. + channel isoforms from human brain. Neuron 13(6):1315-1330
58. Yan J, Olsen J, Park K-S, Li W, Bildl W, Schulte U, Aldrich R, Fakler B, Trimmer J (2008) Profiling the phospho-status of the BKCa channel alpha subunit in rat brain reveals unexpected patterns and complexity. Mol Cell Proteomics 7(11):2188-2198