메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages

Alternative CHRNB4 3′-UTRs Mediate the Allelic Effects of SNP rs1948 on Gene Expression

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; MICRORNA; MICRORNA 138; MICRORNA 3157; UNCLASSIFIED DRUG;

EID: 84877779021     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063699     Document Type: Article
Times cited : (18)

References (81)
  • 1
    • 77950365448 scopus 로고    scopus 로고
    • The effect of alcohol and nicotine abuse on gene expression in the brain
    • Flatscher-Bader T, Wilce PA, (2009) The effect of alcohol and nicotine abuse on gene expression in the brain. Nutrition research reviews 22: 148-162.
    • (2009) Nutrition Research Reviews , vol.22 , pp. 148-162
    • Flatscher-Bader, T.1    Wilce, P.A.2
  • 3
    • 0031791365 scopus 로고    scopus 로고
    • Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism
    • Bierut LJ, Dinwiddie SH, Begleiter H, Crowe RR, Hesselbrock V, et al. (1998) Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism. Archives of general psychiatry 55: 982-988.
    • (1998) Archives of General Psychiatry , vol.55 , pp. 982-988
    • Bierut, L.J.1    Dinwiddie, S.H.2    Begleiter, H.3    Crowe, R.R.4    Hesselbrock, V.5
  • 4
    • 0141567810 scopus 로고    scopus 로고
    • The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women
    • Kendler KS, Prescott CA, Myers J, Neale MC, (2003) The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Archives of general psychiatry 60: 929-937.
    • (2003) Archives of General Psychiatry , vol.60 , pp. 929-937
    • Kendler, K.S.1    Prescott, C.A.2    Myers, J.3    Neale, M.C.4
  • 5
    • 17344367165 scopus 로고    scopus 로고
    • Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities
    • Tsuang MT, Lyons MJ, Meyer JM, Doyle T, Eisen SA, et al. (1998) Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities. Archives of general psychiatry 55: 967-972.
    • (1998) Archives of General Psychiatry , vol.55 , pp. 967-972
    • Tsuang, M.T.1    Lyons, M.J.2    Meyer, J.M.3    Doyle, T.4    Eisen, S.A.5
  • 6
    • 77951711343 scopus 로고    scopus 로고
    • Genome-wide meta-analyses identify multiple loci associated with smoking behavior
    • The Tobacco, Genetics Consortium
    • The Tobacco, Genetics Consortium, (2010) Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nature genetics 42: 441-447.
    • (2010) Nature Genetics , vol.42 , pp. 441-447
  • 7
    • 77951751034 scopus 로고    scopus 로고
    • Meta-analysis and imputation refines the association of 15q25 with smoking quantity
    • Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, et al. (2010) Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nature genetics 42: 436-440.
    • (2010) Nature Genetics , vol.42 , pp. 436-440
    • Liu, J.Z.1    Tozzi, F.2    Waterworth, D.M.3    Pillai, S.G.4    Muglia, P.5
  • 13
    • 0034671380 scopus 로고    scopus 로고
    • Stoichiometry of human recombinant neuronal nicotinic receptors containing the b3 subunit expressed in Xenopus oocytes
    • Boorman JP, Groot-Kormelink PJ, Sivilotti LG, (2000) Stoichiometry of human recombinant neuronal nicotinic receptors containing the b3 subunit expressed in Xenopus oocytes. The Journal of physiology 529 Pt 3: 565-577.
    • (2000) The Journal of Physiology 529 Pt , vol.3 , pp. 565-577
    • Boorman, J.P.1    Groot-Kormelink, P.J.2    Sivilotti, L.G.3
  • 14
    • 78149430216 scopus 로고    scopus 로고
    • Human alpha3beta4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells
    • Krashia P, Moroni M, Broadbent S, Hofmann G, Kracun S, et al. (2010) Human alpha3beta4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells. PloS one 5: e13611.
    • (2010) PloS One , vol.5
    • Krashia, P.1    Moroni, M.2    Broadbent, S.3    Hofmann, G.4    Kracun, S.5
  • 18
    • 40849097777 scopus 로고    scopus 로고
    • Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking
    • Berrettini W, Yuan X, Tozzi F, Song K, Francks C, et al. (2008) Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking. Molecular psychiatry 13: 368-373.
    • (2008) Molecular Psychiatry , vol.13 , pp. 368-373
    • Berrettini, W.1    Yuan, X.2    Tozzi, F.3    Song, K.4    Francks, C.5
  • 19
    • 73049084248 scopus 로고    scopus 로고
    • Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25
    • Bierut LJ, (2010) Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. Trends in pharmacological sciences 31: 46-51.
    • (2010) Trends in Pharmacological Sciences , vol.31 , pp. 46-51
    • Bierut, L.J.1
  • 22
    • 77953219723 scopus 로고    scopus 로고
    • Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes
    • Grucza RA, Johnson EO, Krueger RF, Breslau N, Saccone NL, et al. (2010) Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes. Addiction biology 15: 346-357.
    • (2010) Addiction Biology , vol.15 , pp. 346-357
    • Grucza, R.A.1    Johnson, E.O.2    Krueger, R.F.3    Breslau, N.4    Saccone, N.L.5
  • 23
    • 70149090145 scopus 로고    scopus 로고
    • The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans
    • Saccone NL, Wang JC, Breslau N, Johnson EO, Hatsukami D, et al. (2009) The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. Cancer research 69: 6848-6856.
    • (2009) Cancer Research , vol.69 , pp. 6848-6856
    • Saccone, N.L.1    Wang, J.C.2    Breslau, N.3    Johnson, E.O.4    Hatsukami, D.5
  • 24
    • 33846510020 scopus 로고    scopus 로고
    • Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
    • Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, et al. (2007) Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Human molecular genetics 16: 36-49.
    • (2007) Human Molecular Genetics , vol.16 , pp. 36-49
    • Saccone, S.F.1    Hinrichs, A.L.2    Saccone, N.L.3    Chase, G.A.4    Konvicka, K.5
  • 25
    • 68249094627 scopus 로고    scopus 로고
    • The genetic components of alcohol and nicotine co-addiction: from genes to behavior
    • Schlaepfer IR, Hoft NR, Ehringer MA, (2008) The genetic components of alcohol and nicotine co-addiction: from genes to behavior. Current drug abuse reviews 1: 124-134.
    • (2008) Current Drug Abuse Reviews , vol.1 , pp. 124-134
    • Schlaepfer, I.R.1    Hoft, N.R.2    Ehringer, M.A.3
  • 26
    • 55749093830 scopus 로고    scopus 로고
    • The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer
    • Spitz MR, Amos CI, Dong Q, Lin J, Wu X, (2008) The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer. Journal of the National Cancer Institute 100: 1552-1556.
    • (2008) Journal of the National Cancer Institute , vol.100 , pp. 1552-1556
    • Spitz, M.R.1    Amos, C.I.2    Dong, Q.3    Lin, J.4    Wu, X.5
  • 28
    • 41649103052 scopus 로고    scopus 로고
    • A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
    • Thorgeirsson TE, Geller F, Sulem P, Rafnar T, Wiste A, et al. (2008) A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452: 638-642.
    • (2008) Nature , vol.452 , pp. 638-642
    • Thorgeirsson, T.E.1    Geller, F.2    Sulem, P.3    Rafnar, T.4    Wiste, A.5
  • 29
    • 48249105897 scopus 로고    scopus 로고
    • A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction
    • Weiss RB, Baker TB, Cannon DS, von Niederhausern A, Dunn DM, et al. (2008) A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. PLoS genetics 4: e1000125.
    • (2008) PLoS Genetics , vol.4
    • Weiss, R.B.1    Baker, T.B.2    Cannon, D.S.3    von Niederhausern, A.4    Dunn, D.M.5
  • 30
    • 43049176325 scopus 로고    scopus 로고
    • The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults
    • Schlaepfer IR, Hoft NR, Collins AC, Corley RP, Hewitt JK, et al. (2008) The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults. Biological psychiatry 63: 1039-1046.
    • (2008) Biological Psychiatry , vol.63 , pp. 1039-1046
    • Schlaepfer, I.R.1    Hoft, N.R.2    Collins, A.C.3    Corley, R.P.4    Hewitt, J.K.5
  • 31
    • 65349161502 scopus 로고    scopus 로고
    • Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence
    • Wang JC, Grucza R, Cruchaga C, Hinrichs AL, Bertelsen S, et al. (2009) Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. Molecular psychiatry 14: 501-510.
    • (2009) Molecular Psychiatry , vol.14 , pp. 501-510
    • Wang, J.C.1    Grucza, R.2    Cruchaga, C.3    Hinrichs, A.L.4    Bertelsen, S.5
  • 32
    • 84864187869 scopus 로고    scopus 로고
    • Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects
    • Gallego X, Molas S, Amador-Arjona A, Marks MJ, Robles N, et al. (2012) Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects. Amino acids 43: 897-909.
    • (2012) Amino Acids , vol.43 , pp. 897-909
    • Gallego, X.1    Molas, S.2    Amador-Arjona, A.3    Marks, M.J.4    Robles, N.5
  • 33
    • 84859775671 scopus 로고    scopus 로고
    • Transgenic over expression of nicotinic receptor alpha 5, alpha 3, and beta 4 subunit genes reduces ethanol intake in mice
    • Gallego X, Ruiz-Medina J, Valverde O, Molas S, Robles N, et al. (2012) Transgenic over expression of nicotinic receptor alpha 5, alpha 3, and beta 4 subunit genes reduces ethanol intake in mice. Alcohol 46: 205-215.
    • (2012) Alcohol , vol.46 , pp. 205-215
    • Gallego, X.1    Ruiz-Medina, J.2    Valverde, O.3    Molas, S.4    Robles, N.5
  • 34
    • 79953246461 scopus 로고    scopus 로고
    • Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake
    • Fowler CD, Lu Q, Johnson PM, Marks MJ, Kenny PJ, (2011) Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake. Nature 471: 597-601.
    • (2011) Nature , vol.471 , pp. 597-601
    • Fowler, C.D.1    Lu, Q.2    Johnson, P.M.3    Marks, M.J.4    Kenny, P.J.5
  • 35
    • 79955658475 scopus 로고    scopus 로고
    • Aversion to nicotine is regulated by the balanced activity of beta4 and alpha5 nicotinic receptor subunits in the medial habenula
    • Frahm S, Slimak MA, Ferrarese L, Santos-Torres J, Antolin-Fontes B, et al. (2011) Aversion to nicotine is regulated by the balanced activity of beta4 and alpha5 nicotinic receptor subunits in the medial habenula. Neuron 70: 522-535.
    • (2011) Neuron , vol.70 , pp. 522-535
    • Frahm, S.1    Slimak, M.A.2    Ferrarese, L.3    Santos-Torres, J.4    Antolin-Fontes, B.5
  • 36
    • 0029960799 scopus 로고    scopus 로고
    • Transcriptional regulation and cell specificity determinants of the rat nicotinic acetylcholine receptor alpha 3 gene
    • Boyd RT, (1996) Transcriptional regulation and cell specificity determinants of the rat nicotinic acetylcholine receptor alpha 3 gene. Neuroscience letters 208: 73-76.
    • (1996) Neuroscience Letters , vol.208 , pp. 73-76
    • Boyd, R.T.1
  • 37
    • 77249123836 scopus 로고    scopus 로고
    • Temporally- and spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor beta4 subunit gene promoter
    • Bruschweiler-Li L, Fuentes Medel YF, Scofield MD, Trang EB, Binke SA, et al. (2010) Temporally- and spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor beta4 subunit gene promoter. Neuroscience 166: 864-877.
    • (2010) Neuroscience , vol.166 , pp. 864-877
    • Bruschweiler-Li, L.1    Fuentes Medel, Y.F.2    Scofield, M.D.3    Trang, E.B.4    Binke, S.A.5
  • 38
    • 0034732161 scopus 로고    scopus 로고
    • Transcriptional control of the neuronal nicotinic acetylcholine receptor gene cluster by the beta43' enhancer, Sp1, SCIP and ETS transcription factors
    • Deneris ES, Francis N, McDonough J, Fyodorov D, Miller T, et al. (2000) Transcriptional control of the neuronal nicotinic acetylcholine receptor gene cluster by the beta43' enhancer, Sp1, SCIP and ETS transcription factors. European journal of pharmacology 393: 69-74.
    • (2000) European Journal of Pharmacology , vol.393 , pp. 69-74
    • Deneris, E.S.1    Francis, N.2    McDonough, J.3    Fyodorov, D.4    Miller, T.5
  • 39
    • 0037155167 scopus 로고    scopus 로고
    • Retinal neuron activity of ETS domain-binding sites in a nicotinic acetylcholine receptor gene cluster enhancer
    • Francis N, Deneris ES, (2002) Retinal neuron activity of ETS domain-binding sites in a nicotinic acetylcholine receptor gene cluster enhancer. The Journal of biological chemistry 277: 6511-6519.
    • (2002) The Journal of Biological Chemistry , vol.277 , pp. 6511-6519
    • Francis, N.1    Deneris, E.S.2
  • 40
    • 0028120674 scopus 로고
    • Nerve growth factor increases the transcriptional activity of the rat neuronal nicotinic acetylcholine receptor beta 4 subunit promoter in transfected PC12 cells
    • Hu M, Whiting Theobald NL, Gardner PD, (1994) Nerve growth factor increases the transcriptional activity of the rat neuronal nicotinic acetylcholine receptor beta 4 subunit promoter in transfected PC12 cells. Journal of neurochemistry 62: 392-395.
    • (1994) Journal of Neurochemistry , vol.62 , pp. 392-395
    • Hu, M.1    Whiting Theobald, N.L.2    Gardner, P.D.3
  • 42
    • 0030608632 scopus 로고    scopus 로고
    • beta43': An enhancer displaying neural-restricted activity is located in the 3′-untranslated exon of the rat nicotinic acetylcholine receptor beta4 gene
    • McDonough J, Deneris E, (1997) beta43': An enhancer displaying neural-restricted activity is located in the 3′-untranslated exon of the rat nicotinic acetylcholine receptor beta4 gene. The Journal of neuroscience: the official journal of the Society for Neuroscience 17: 2273-2283.
    • (1997) The Journal of Neuroscience: The Official Journal of the Society for Neuroscience , vol.17 , pp. 2273-2283
    • McDonough, J.1    Deneris, E.2
  • 43
    • 0034666008 scopus 로고    scopus 로고
    • Regulation of transcription in the neuronal nicotinic receptor subunit gene cluster by a neuron-selective enhancer and ETS domain factors
    • McDonough J, Francis N, Miller T, Deneris ES, (2000) Regulation of transcription in the neuronal nicotinic receptor subunit gene cluster by a neuron-selective enhancer and ETS domain factors. The Journal of biological chemistry 275: 28962-28970.
    • (2000) The Journal of Biological Chemistry , vol.275 , pp. 28962-28970
    • McDonough, J.1    Francis, N.2    Miller, T.3    Deneris, E.S.4
  • 44
    • 34547092958 scopus 로고    scopus 로고
    • Transcriptional repression by a conserved intronic sequence in the nicotinic receptor alpha3 subunit gene
    • Medel YF, Gardner PD, (2007) Transcriptional repression by a conserved intronic sequence in the nicotinic receptor alpha3 subunit gene. The Journal of biological chemistry 282: 19062-19070.
    • (2007) The Journal of Biological Chemistry , vol.282 , pp. 19062-19070
    • Medel, Y.F.1    Gardner, P.D.2
  • 45
    • 0035374340 scopus 로고    scopus 로고
    • The signal transduction pathway underlying ion channel gene regulation by SP1-C-Jun interactions
    • Melnikova IN, Gardner PD, (2001) The signal transduction pathway underlying ion channel gene regulation by SP1-C-Jun interactions. The Journal of biological chemistry 276: 19040-19045.
    • (2001) The Journal of Biological Chemistry , vol.276 , pp. 19040-19045
    • Melnikova, I.N.1    Gardner, P.D.2
  • 46
    • 41749086707 scopus 로고    scopus 로고
    • Transcription factor assembly on the nicotinic receptor beta4 subunit gene promoter
    • Scofield MD, Bruschweiler-Li L, Mou Z, Gardner PD, (2008) Transcription factor assembly on the nicotinic receptor beta4 subunit gene promoter. Neuroreport 19: 687-690.
    • (2008) Neuroreport , vol.19 , pp. 687-690
    • Scofield, M.D.1    Bruschweiler-Li, L.2    Mou, Z.3    Gardner, P.D.4
  • 47
    • 77957115270 scopus 로고    scopus 로고
    • A transcriptional regulatory element critical for CHRNB4 promoter activity in vivo
    • Scofield MD, Tapper AR, Gardner PD, (2010) A transcriptional regulatory element critical for CHRNB4 promoter activity in vivo. Neuroscience 170: 1056-1064.
    • (2010) Neuroscience , vol.170 , pp. 1056-1064
    • Scofield, M.D.1    Tapper, A.R.2    Gardner, P.D.3
  • 48
    • 33746512547 scopus 로고    scopus 로고
    • Shared long-range regulatory elements coordinate expression of a gene cluster encoding nicotinic receptor heteromeric subtypes
    • Xu X, Scott MM, Deneris ES, (2006) Shared long-range regulatory elements coordinate expression of a gene cluster encoding nicotinic receptor heteromeric subtypes. Molecular and cellular biology 26: 5636-5649.
    • (2006) Molecular and Cellular Biology , vol.26 , pp. 5636-5649
    • Xu, X.1    Scott, M.M.2    Deneris, E.S.3
  • 49
    • 0028938246 scopus 로고
    • Transcriptional analysis of acetylcholine receptor alpha 3 gene promoter motifs that bind Sp1 and AP2
    • Yang X, Fyodorov D, Deneris ES, (1995) Transcriptional analysis of acetylcholine receptor alpha 3 gene promoter motifs that bind Sp1 and AP2. The Journal of biological chemistry 270: 8514-8520.
    • (1995) The Journal of Biological Chemistry , vol.270 , pp. 8514-8520
    • Yang, X.1    Fyodorov, D.2    Deneris, E.S.3
  • 50
    • 0031052648 scopus 로고    scopus 로고
    • Elements between the protein-coding regions of the adjacent beta 4 and alpha 3 acetylcholine receptor genes direct neuron-specific expression in the central nervous system
    • Yang X, Yang F, Fyodorov D, Wang F, McDonough J, et al. (1997) Elements between the protein-coding regions of the adjacent beta 4 and alpha 3 acetylcholine receptor genes direct neuron-specific expression in the central nervous system. Journal of neurobiology 32: 311-324.
    • (1997) Journal of Neurobiology , vol.32 , pp. 311-324
    • Yang, X.1    Yang, F.2    Fyodorov, D.3    Wang, F.4    McDonough, J.5
  • 51
    • 0031845860 scopus 로고    scopus 로고
    • Expression and transcriptional regulation of the human alpha3 neuronal nicotinic receptor subunit in T lymphocyte cell lines
    • Battaglioli E, Gotti C, Terzano S, Flora A, Clementi F, et al. (1998) Expression and transcriptional regulation of the human alpha3 neuronal nicotinic receptor subunit in T lymphocyte cell lines. Journal of neurochemistry 71: 1261-1270.
    • (1998) Journal of Neurochemistry , vol.71 , pp. 1261-1270
    • Battaglioli, E.1    Gotti, C.2    Terzano, S.3    Flora, A.4    Clementi, F.5
  • 52
    • 34250356011 scopus 로고    scopus 로고
    • Transcription factor PHOX2A regulates the human alpha3 nicotinic receptor subunit gene promoter
    • Benfante R, Flora A, Di Lascio S, Cargnin F, Longhi R, et al. (2007) Transcription factor PHOX2A regulates the human alpha3 nicotinic receptor subunit gene promoter. The Journal of biological chemistry 282: 13290-13302.
    • (2007) The Journal of Biological Chemistry , vol.282 , pp. 13290-13302
    • Benfante, R.1    Flora, A.2    Di Lascio, S.3    Cargnin, F.4    Longhi, R.5
  • 53
    • 0031035848 scopus 로고    scopus 로고
    • Structural and functional characterization of the human alpha3 nicotinic subunit gene promoter
    • Fornasari D, Battaglioli E, Flora A, Terzano S, Clementi F, (1997) Structural and functional characterization of the human alpha3 nicotinic subunit gene promoter. Molecular pharmacology 51: 250-261.
    • (1997) Molecular Pharmacology , vol.51 , pp. 250-261
    • Fornasari, D.1    Battaglioli, E.2    Flora, A.3    Terzano, S.4    Clementi, F.5
  • 54
    • 67449119418 scopus 로고    scopus 로고
    • Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations
    • Wu C, Hu Z, Yu D, Huang L, Jin G, et al. (2009) Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations. Cancer research 69: 5065-5072.
    • (2009) Cancer Research , vol.69 , pp. 5065-5072
    • Wu, C.1    Hu, Z.2    Yu, D.3    Huang, L.4    Jin, G.5
  • 55
    • 80051615692 scopus 로고    scopus 로고
    • In vitro and ex vivo analysis of CHRNA3 and CHRNA5 haplotype expression
    • Doyle GA, Wang MJ, Chou AD, Oleynick JU, Arnold SE, et al. (2011) In vitro and ex vivo analysis of CHRNA3 and CHRNA5 haplotype expression. PloS one 6: e23373.
    • (2011) PloS One , vol.6
    • Doyle, G.A.1    Wang, M.J.2    Chou, A.D.3    Oleynick, J.U.4    Arnold, S.E.5
  • 58
    • 66949168048 scopus 로고    scopus 로고
    • A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
    • Siegel G, Obernosterer G, Fiore R, Oehmen M, Bicker S, et al. (2009) A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nature cell biology 11: 705-716.
    • (2009) Nature Cell Biology , vol.11 , pp. 705-716
    • Siegel, G.1    Obernosterer, G.2    Fiore, R.3    Oehmen, M.4    Bicker, S.5
  • 61
    • 79951783389 scopus 로고    scopus 로고
    • CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences
    • Hoft NR, Stitzel JA, Hutchison KE, Ehringer MA, (2011) CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences. Genes, brain, and behavior 10: 176-185.
    • (2011) Genes, Brain, and Behavior , vol.10 , pp. 176-185
    • Hoft, N.R.1    Stitzel, J.A.2    Hutchison, K.E.3    Ehringer, M.A.4
  • 62
    • 34250346512 scopus 로고    scopus 로고
    • alpha7 nicotinic receptor gene promoter polymorphisms in inbred mice affect expression in a cell type-specific fashion
    • Mexal S, Jenkins PM, Lautner MA, Iacob E, Crouch EL, et al. (2007) alpha7 nicotinic receptor gene promoter polymorphisms in inbred mice affect expression in a cell type-specific fashion. The Journal of biological chemistry 282: 13220-13227.
    • (2007) The Journal of Biological Chemistry , vol.282 , pp. 13220-13227
    • Mexal, S.1    Jenkins, P.M.2    Lautner, M.A.3    Iacob, E.4    Crouch, E.L.5
  • 63
    • 0026013289 scopus 로고
    • Mapping of multiple subunits of the neuronal nicotinic acetylcholine receptor to chromosome 15 in man and chromosome 9 in mouse
    • Eng CM, Kozak CA, Beaudet AL, Zoghbi HY, (1991) Mapping of multiple subunits of the neuronal nicotinic acetylcholine receptor to chromosome 15 in man and chromosome 9 in mouse. Genomics 9: 278-282.
    • (1991) Genomics , vol.9 , pp. 278-282
    • Eng, C.M.1    Kozak, C.A.2    Beaudet, A.L.3    Zoghbi, H.Y.4
  • 64
    • 0026552017 scopus 로고
    • Chromosomal localization and physical linkage of the genes encoding the human alpha 3, alpha 5, and beta 4 neuronal nicotinic receptor subunits
    • Raimondi E, Rubboli F, Moralli D, Chini B, Fornasari D, et al. (1992) Chromosomal localization and physical linkage of the genes encoding the human alpha 3, alpha 5, and beta 4 neuronal nicotinic receptor subunits. Genomics 12: 849-850.
    • (1992) Genomics , vol.12 , pp. 849-850
    • Raimondi, E.1    Rubboli, F.2    Moralli, D.3    Chini, B.4    Fornasari, D.5
  • 65
    • 0032033808 scopus 로고    scopus 로고
    • Genetic mapping of CHRNA3 and CHRNB4 to pig chromosome 7 extends the syntenic conservation with human chromosome 15 and mouse chromosome 9
    • Tammen I, (1998) Genetic mapping of CHRNA3 and CHRNB4 to pig chromosome 7 extends the syntenic conservation with human chromosome 15 and mouse chromosome 9. Mammalian genome: official journal of the International Mammalian Genome Society 9: 263-264.
    • (1998) Mammalian Genome: Official Journal of the International Mammalian Genome Society , vol.9 , pp. 263-264
    • Tammen, I.1
  • 66
    • 0035984473 scopus 로고    scopus 로고
    • Evolutionary dynamics of mammalian mRNA untranslated regions by comparative analysis of orthologous human, artiodactyl and rodent gene pairs
    • Larizza A, Makalowski W, Pesole G, Saccone C, (2002) Evolutionary dynamics of mammalian mRNA untranslated regions by comparative analysis of orthologous human, artiodactyl and rodent gene pairs. Computers & chemistry 26: 479-490.
    • (2002) Computers & Chemistry , vol.26 , pp. 479-490
    • Larizza, A.1    Makalowski, W.2    Pesole, G.3    Saccone, C.4
  • 67
    • 0035802386 scopus 로고    scopus 로고
    • Structural and functional features of eukaryotic mRNA untranslated regions
    • Pesole G, Mignone F, Gissi C, Grillo G, Licciulli F, et al. (2001) Structural and functional features of eukaryotic mRNA untranslated regions. Gene 276: 73-81.
    • (2001) Gene , vol.276 , pp. 73-81
    • Pesole, G.1    Mignone, F.2    Gissi, C.3    Grillo, G.4    Licciulli, F.5
  • 68
    • 0042968976 scopus 로고    scopus 로고
    • The power of the 3' UTR: translational control and development
    • Kuersten S, Goodwin EB, (2003) The power of the 3' UTR: translational control and development. Nature reviews Genetics 4: 626-637.
    • (2003) Nature Reviews Genetics , vol.4 , pp. 626-637
    • Kuersten, S.1    Goodwin, E.B.2
  • 69
    • 0037308625 scopus 로고    scopus 로고
    • Translational control by the 3′-UTR: the ends specify the means
    • Mazumder B, Seshadri V, Fox PL, (2003) Translational control by the 3′-UTR: the ends specify the means. Trends in biochemical sciences 28: 91-98.
    • (2003) Trends in Biochemical Sciences , vol.28 , pp. 91-98
    • Mazumder, B.1    Seshadri, V.2    Fox, P.L.3
  • 71
    • 33845755467 scopus 로고    scopus 로고
    • Illuminating the silence: understanding the structure and function of small RNAs
    • Rana TM, (2007) Illuminating the silence: understanding the structure and function of small RNAs. Nature reviews Molecular cell biology 8: 23-36.
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , pp. 23-36
    • Rana, T.M.1
  • 72
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites
    • Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB, (2008) Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites. Science 320: 1643-1647.
    • (2008) Science , vol.320 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 73
    • 79955554179 scopus 로고    scopus 로고
    • Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing
    • Fu Y, Sun Y, Li Y, Li J, Rao X, et al. (2011) Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing. Genome research 21: 741-747.
    • (2011) Genome Research , vol.21 , pp. 741-747
    • Fu, Y.1    Sun, Y.2    Li, Y.3    Li, J.4    Rao, X.5
  • 74
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr C, Bartel DP, (2009) Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 138: 673-684.
    • (2009) Cell , vol.138 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 75
    • 0030266993 scopus 로고    scopus 로고
    • RNA structure and the regulation of gene expression
    • Klaff P, Riesner D, Steger G, (1996) RNA structure and the regulation of gene expression. Plant molecular biology 32: 89-106.
    • (1996) Plant Molecular Biology , vol.32 , pp. 89-106
    • Klaff, P.1    Riesner, D.2    Steger, G.3
  • 77
    • 0032526427 scopus 로고    scopus 로고
    • Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
    • Fan XC, Steitz JA, (1998) Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. The EMBO journal 17: 3448-3460.
    • (1998) The EMBO Journal , vol.17 , pp. 3448-3460
    • Fan, X.C.1    Steitz, J.A.2
  • 78
    • 0033557214 scopus 로고    scopus 로고
    • 3′-Terminal RNA structures and poly(U) tracts inhibit initiation by a 3'->5' exonuclease in vitro
    • Ford LP, Wilusz J, (1999) 3′-Terminal RNA structures and poly(U) tracts inhibit initiation by a 3'->5' exonuclease in vitro. Nucleic acids research 27: 1159-1167.
    • (1999) Nucleic Acids Research , vol.27 , pp. 1159-1167
    • Ford, L.P.1    Wilusz, J.2
  • 80
    • 84856079279 scopus 로고    scopus 로고
    • Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence
    • Haller G, Druley T, Vallania FL, Mitra RD, Li P, et al. (2012) Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence. Human molecular genetics 21: 647-655.
    • (2012) Human Molecular Genetics , vol.21 , pp. 647-655
    • Haller, G.1    Druley, T.2    Vallania, F.L.3    Mitra, R.D.4    Li, P.5
  • 81
    • 84863349878 scopus 로고    scopus 로고
    • Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking
    • Kapoor M, Wang JC, Bertelsen S, Bucholz K, Budde JP, et al. (2012) Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking. PloS one 7: e33513.
    • (2012) PloS One , vol.7
    • Kapoor, M.1    Wang, J.C.2    Bertelsen, S.3    Bucholz, K.4    Budde, J.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.