Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-κB1 p105 complex in co-transfected HEK-293 cells

Biochemical Journal

Volumn 452, Issue 2, 2013, Pages 359-365

  Gantke, Thorsten ^a   Boussouf, Sabrina ^a,d   Janzen, Julia ^a   Morrice, Nicholas A ^b   Howell, Steven ^a   Mühlberger, Elke ^c   Ley, Steven C ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

A20 binding inhibitor of nuclear factor B 2 (ABIN 2); Cancer Osaka thyroid (COT); Double stranded RNA dependent protein kinase (PKR); Nuclear factor B 1 (NF B1); Tumour progression locus 2 (TPL 2); Virus protein 35 (VP35)

Indexed keywords

A20 BINDING INHIBITOR OF NUCLEAR FACTOR KAPPA B 2; CARISOPRODOL; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEAR FACTOR KAPPA B 1; PROTEIN KINASE R; PROTEIN P105; PROTEIN SERINE THREONINE KINASE; PROTEIN VP35; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR REL; TUMOR PROGRESSION LOCUS 2; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOLYSIS; EBOLA VIRUS; EXPRESSION VECTOR; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; TRANSIENT EXPRESSION; TRANSIENT TRANSFECTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; EBOLAVIRUS; HEK293 CELLS; HUMANS; MAP KINASE KINASE KINASES; MULTIPROTEIN COMPLEXES; NF-KAPPA B P50 SUBUNIT; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; TRANSFECTION; UP-REGULATION; VIRAL REGULATORY AND ACCESSORY PROTEINS;

EID: 84877763205     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121873     Document Type: Article

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