SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes

Journal of Biological Chemistry

Volumn 288, Issue 19, 2013, Pages 13850-13862

  Balasubramaniyan, Natarajan ^a   Luo, Yuhuan ^a   Sun, An Qiang ^a   Suchy, Frederick J ^a  

^a Children's Hospital Colorado   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR PROCESS; FARNESOID X RECEPTORS; NUCLEAR RECEPTORS; POST-TRANSLATION MODIFICATION; SMALL UBIQUITIN-LIKE MODIFIERS; SUMOYLATION; TARGET GENES; TRANSCRIPTIONAL ACTIVATORS;

TRANSCRIPTION FACTORS;

GENES;

FARNESOID X RECEPTOR; LIGAND; LYSINE; RETINOID X RECEPTOR ALPHA; SMALL INTERFERING RNA; SUMO 1 PROTEIN; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE SALT EXPORT PUMP GENE; CELL NUCLEUS; CELL STRAIN HEPG2; CHOLESTASIS; CONTROLLED STUDY; COVALENT BOND; GENE; GENE EXPRESSION REGULATION; GENE MUTATION; GENE TARGETING; GENETIC CONSERVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTALPHA GENE; OSTBETA GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SMALL HETERODIMER PARTNER GENE; SUMOYLATION; TRANSACTIVATION;

ABC TRANSPORTER; BILE ACID TRANSPORTERS; CHOLESTASIS; CHROMATIN HISTONE MODIFICATION; GENE REGULATION; GENE TRANSCRIPTION; HISTONE MODIFICATIONS; NUCLEAR RECEPTORS;

AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTASIS; CHROMATIN; CONSENSUS SEQUENCE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HUMANS; LIVER; MICE; MICE, INBRED C57BL; MUTAGENESIS, SITE-DIRECTED; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, SMALL INTERFERING; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; SUMO-1 PROTEIN; SUMOYLATION; TRANSCRIPTION, GENETIC;

EID: 84877710429     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.443937     Document Type: Article

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