Direct methylation of FXR by set7/9, a lysine methyltransferase, regulates the expression of FXR target genes

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 302, Issue 9, 2012, Pages

  Balasubramaniyan, Natarajan ^a   Ananthanarayanan, Meena ^b   Suchy, Frederick J ^a  

^a Children's Hospital Colorado   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bile acid metabolism; Epigenetics; Farnesoid X receptor; Gene regulation

Indexed keywords

ARGININE; BILE SALT; FARNESOID X RECEPTOR; GLUTATHIONE TRANSFERASE A1; HETERODIMER; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; MESSENGER RNA; RETINOID X RECEPTOR; SET7 9 METHYLTRANSFERASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHROMATIN; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; HISTONE METHYLATION; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN INTERACTION; RECEPTOR BINDING;

ANIMALS; CELL LINE; GENE EXPRESSION REGULATION; HAPLORHINI; HEPATOCYTES; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; KIDNEY; METHYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTIONAL ACTIVATION;

EID: 84860535483     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00441.2011     Document Type: Article

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