Synstatin: A selective inhibitor of the syndecan-1-coupled IGF1R-αvβ3 integrin complex in tumorigenesis and angiogenesis

FEBS Journal

Volumn 280, Issue 10, 2013, Pages 2207-2215

  Rapraeger, Alan C ^a  

^a University of Wisconsin Health   (United States)

Author keywords

cell adhesion; extracellular matrix; heparan sulfate; metastasis; proteoglycan; recombinant protein; therapeutic agent; VE cadherin; VEGF; VEGFR2

Indexed keywords

ANTINEOPLASTIC AGENT; SOMATOMEDIN C RECEPTOR; SYNDECAN 1; SYNSTATIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN RECEPTOR 2; VITRONECTIN RECEPTOR;

ANGIOGENESIS; BREAST CARCINOMA; CANCER CELL; CARCINOGENESIS; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL SURVIVAL; COMPETITIVE INHIBITION; COMPLEX FORMATION; DRUG TARGETING; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TUMOR VASCULARIZATION;

ANIMALS; ANTIGENS, CD; CADHERINS; CELL ADHESION; CELL TRANSFORMATION, NEOPLASTIC; ENDOTHELIAL CELLS; HUMANS; INTEGRIN ALPHAVBETA3; MICE; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDES; PROTEIN BINDING; RECEPTOR, IGF TYPE 1; RECOMBINANT PROTEINS; SYNDECAN-1; TERNARY COMPLEX FACTORS;

EID: 84877692916     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12160     Document Type: Review

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