메뉴 건너뛰기




Volumn 15, Issue 3, 2013, Pages

Delivery of gene silencing agents for breast cancer therapy

Author keywords

[No Author keywords available]

Indexed keywords

CREMOPHOR; DOCETAXEL; DOXORUBICIN; MICRORNA; PACLITAXEL; SHORT HAIRPIN RNA; SMALL INHIBITORY RNA; SMALL INTERFERING RNA; SMALL NONCODING MICRORNA; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 84877650524     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr3413     Document Type: Article
Times cited : (29)

References (52)
  • 2
    • 79960985571 scopus 로고    scopus 로고
    • Structure-based druggability assessment-identifying suitable targets for small molecule therapeutics
    • 10.1016/j.cbpa.2011.05.020, 21704549
    • Fauman EB, Rai BK, Huang ES. Structure-based druggability assessment-identifying suitable targets for small molecule therapeutics. Curr Opin Chem Biol 2011, 15:463-468. 10.1016/j.cbpa.2011.05.020, 21704549.
    • (2011) Curr Opin Chem Biol , vol.15 , pp. 463-468
    • Fauman, E.B.1    Rai, B.K.2    Huang, E.S.3
  • 3
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • 10.1038/35888, 9486653
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-811. 10.1038/35888, 9486653.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 4
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • 10.1038/35078107, 11373684
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001, 411:494-498. 10.1038/35078107, 11373684.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 9
    • 84862638243 scopus 로고    scopus 로고
    • Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN
    • 10.1371/journal.pone.0039520, 3382593, 22761812
    • Han M, Liu M, Wang Y, Chen X, Xu J, Sun Y, Zhao L, Qu H, Fan Y, Wu C. Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS One 2012, 7:e39520. 10.1371/journal.pone.0039520, 3382593, 22761812.
    • (2012) PLoS One , vol.7
    • Han, M.1    Liu, M.2    Wang, Y.3    Chen, X.4    Xu, J.5    Sun, Y.6    Zhao, L.7    Qu, H.8    Fan, Y.9    Wu, C.10
  • 13
    • 77949632782 scopus 로고    scopus 로고
    • Frontiers in cancer nanomedicine: directing mass transport through biological barriers
    • 10.1016/j.tibtech.2009.12.007, 2843761, 20079548
    • Ferrari M. Frontiers in cancer nanomedicine: directing mass transport through biological barriers. Trends Biotechnol 2010, 28:181-188. 10.1016/j.tibtech.2009.12.007, 2843761, 20079548.
    • (2010) Trends Biotechnol , vol.28 , pp. 181-188
    • Ferrari, M.1
  • 14
    • 11144357506 scopus 로고    scopus 로고
    • Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment of metastatic breast cancer
    • 10.1093/annonc/mdh097, 14998846, CAELYX Breast Cancer Study Group
    • O'Brien ME, Wigler N, Inbar M, Rosso R, Grischke E, Santoro A, Catane R, Kieback DG, Tomczak P, Ackland SP, Orlandi F, Mellars L, Alland L, Tendler C, CAELYX Breast Cancer Study Group Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment of metastatic breast cancer. Ann Oncol 2004, 15:440-449. 10.1093/annonc/mdh097, 14998846, CAELYX Breast Cancer Study Group.
    • (2004) Ann Oncol , vol.15 , pp. 440-449
    • O'Brien, M.E.1    Wigler, N.2    Inbar, M.3    Rosso, R.4    Grischke, E.5    Santoro, A.6    Catane, R.7    Kieback, D.G.8    Tomczak, P.9    Ackland, S.P.10    Orlandi, F.11    Mellars, L.12    Alland, L.13    Tendler, C.14
  • 15
    • 0035282073 scopus 로고    scopus 로고
    • Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer
    • Batist G, Ramakrishnan G, Rao CS, Chandrasekharan A, Gutheil J, Guthrie T, Shah P, Khojasteh A, Nair MK, Hoelzer K, Tkaczuk K, Park YC, Lee LW. Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer. J Clin Oncol 2001, 19:1444-1454.
    • (2001) J Clin Oncol , vol.19 , pp. 1444-1454
    • Batist, G.1    Ramakrishnan, G.2    Rao, C.S.3    Chandrasekharan, A.4    Gutheil, J.5    Guthrie, T.6    Shah, P.7    Khojasteh, A.8    Nair, M.K.9    Hoelzer, K.10    Tkaczuk, K.11    Park, Y.C.12    Lee, L.W.13
  • 16
    • 32944482677 scopus 로고    scopus 로고
    • Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer
    • 10.1200/JCO.2005.04.937, 16172456
    • Gradishar WJ, Tjulandin S, Davidson N, Shaw H, Desai N, Bhar P, Hawkins M, O'Shaughnessy J. Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J Clin Oncol 2005, 23:7794-7803. 10.1200/JCO.2005.04.937, 16172456.
    • (2005) J Clin Oncol , vol.23 , pp. 7794-7803
    • Gradishar, W.J.1    Tjulandin, S.2    Davidson, N.3    Shaw, H.4    Desai, N.5    Bhar, P.6    Hawkins, M.7    O'Shaughnessy, J.8
  • 17
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting
    • 10.1016/S0065-2571(00)00013-3, 11384745
    • Maeda H. The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv Enzyme Regul 2001, 41:189-207. 10.1016/S0065-2571(00)00013-3, 11384745.
    • (2001) Adv Enzyme Regul , vol.41 , pp. 189-207
    • Maeda, H.1
  • 18
    • 12344312042 scopus 로고    scopus 로고
    • Cellular abnormalities of blood vessels as targets in cancer
    • 10.1016/j.gde.2004.12.005, 15661540
    • Baluk P, Hashizume H, McDonald DM. Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev 2005, 15:102-111. 10.1016/j.gde.2004.12.005, 15661540.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 102-111
    • Baluk, P.1    Hashizume, H.2    McDonald, D.M.3
  • 19
    • 39049171058 scopus 로고    scopus 로고
    • Liposomal nanomedicines
    • 10.1517/17425247.5.1.25, 18095927
    • Fenske DB, Cullis PR. Liposomal nanomedicines. Expert Opin Drug Deliv 2008, 5:25-44. 10.1517/17425247.5.1.25, 18095927.
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 25-44
    • Fenske, D.B.1    Cullis, P.R.2
  • 23
    • 84859461033 scopus 로고    scopus 로고
    • Inhibition of p42 MAPK using a nonviral vectordelivered siRNA potentiates the antitumor effect of metformin in prostate cancer cells
    • 10.2217/nnm.11.61, 21995500
    • Monteagudo S, Perez-Martinez FC, Perez-Carrion MD, Guerra J, Merino S, Sanchez-Verdu MP, Cena V. Inhibition of p42 MAPK using a nonviral vectordelivered siRNA potentiates the antitumor effect of metformin in prostate cancer cells. Nanomedicine (Lond) 2012, 7:493-506. 10.2217/nnm.11.61, 21995500.
    • (2012) Nanomedicine (Lond) , vol.7 , pp. 493-506
    • Monteagudo, S.1    Perez-Martinez, F.C.2    Perez-Carrion, M.D.3    Guerra, J.4    Merino, S.5    Sanchez-Verdu, M.P.6    Cena, V.7
  • 25
    • 84555202691 scopus 로고    scopus 로고
    • P-glycoprotein silencing with siRNA delivered by DOPE-modified PEI overcomes doxorubicin resistance in breast cancer cells
    • 10.2217/nnm.11.93, 3422569, 22191778
    • Navarro G, Sawant RR, Biswas S, Essex S, Tros de Ilarduya C, Torchilin VP. P-glycoprotein silencing with siRNA delivered by DOPE-modified PEI overcomes doxorubicin resistance in breast cancer cells. Nanomedicine (Lond) 2012, 7:65-78. 10.2217/nnm.11.93, 3422569, 22191778.
    • (2012) Nanomedicine (Lond) , vol.7 , pp. 65-78
    • Navarro, G.1    Sawant, R.R.2    Biswas, S.3    Essex, S.4    Tros de Ilarduya, C.5    Torchilin, V.P.6
  • 26
    • 84858793517 scopus 로고    scopus 로고
    • Self-assembled RNA interference microsponges for efficient siRNA delivery
    • 10.1038/nmat3253, 22367004
    • Lee JB, Hong J, Bonner DK, Poon Z, Hammond PT. Self-assembled RNA interference microsponges for efficient siRNA delivery. Nat Mater 2012, 11:316-322. 10.1038/nmat3253, 22367004.
    • (2012) Nat Mater , vol.11 , pp. 316-322
    • Lee, J.B.1    Hong, J.2    Bonner, D.K.3    Poon, Z.4    Hammond, P.T.5
  • 28
    • 65649085603 scopus 로고    scopus 로고
    • Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice
    • 10.1172/JCI37515, 2648695, 19229107
    • Judge AD, Robbins M, Tavakoli I, Levi J, Hu L, Fronda A, Ambegia E, McClintock K, MacLachlan I. Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice. J Clin Invest 2009, 119:661-673. 10.1172/JCI37515, 2648695, 19229107.
    • (2009) J Clin Invest , vol.119 , pp. 661-673
    • Judge, A.D.1    Robbins, M.2    Tavakoli, I.3    Levi, J.4    Hu, L.5    Fronda, A.6    Ambegia, E.7    McClintock, K.8    MacLachlan, I.9
  • 32
    • 84877681517 scopus 로고    scopus 로고
    • ClinicalTrials.gov: Study With Atu027 in Patients With Advanced Solid Cancer
    • ClinicalTrials.gov: Study With Atu027 in Patients With Advanced Solid Cancer. , http://www.clinicaltrials.gov/ct2/show/NCT00938574?term=atu027&rank = 1
  • 33
    • 23044506285 scopus 로고    scopus 로고
    • Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery
    • 10.1158/0008-5472.CAN-05-0530, 16061675
    • Landen CN, Chavez-Reyes A, Bucana C, Schmandt R, Deavers MT, Lopez-Berestein G, Sood AK. Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery. Cancer Res 2005, 65:6910-6918. 10.1158/0008-5472.CAN-05-0530, 16061675.
    • (2005) Cancer Res , vol.65 , pp. 6910-6918
    • Landen, C.N.1    Chavez-Reyes, A.2    Bucana, C.3    Schmandt, R.4    Deavers, M.T.5    Lopez-Berestein, G.6    Sood, A.K.7
  • 35
    • 84877652267 scopus 로고    scopus 로고
    • ClinicalTrials.gov: EphA2 Gene Targeting Using Neutral Liposomal Small Interfering RNA Delivery
    • ClinicalTrials.gov: EphA2 Gene Targeting Using Neutral Liposomal Small Interfering RNA Delivery. , http://www.clinicaltrials.gov/ct2/show/NCT01591356?term=EphA2&rank = 1
  • 36
    • 77951132901 scopus 로고    scopus 로고
    • Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
    • 10.1038/nature08956, 2855406, 20305636
    • Davis ME, Zuckerman JE, Choi CH, Seligson D, Tolcher A, Alabi CA, Yen Y, Heidel JD, Ribas A. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 2010, 464:1067-1070. 10.1038/nature08956, 2855406, 20305636.
    • (2010) Nature , vol.464 , pp. 1067-1070
    • Davis, M.E.1    Zuckerman, J.E.2    Choi, C.H.3    Seligson, D.4    Tolcher, A.5    Alabi, C.A.6    Yen, Y.7    Heidel, J.D.8    Ribas, A.9
  • 37
    • 0345357073 scopus 로고    scopus 로고
    • Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery
    • 10.1021/bc034125f, 14624625
    • Bellocq NC, Pun SH, Jensen GS, Davis ME. Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery. Bioconjug Chem 2003, 14:1122-1132. 10.1021/bc034125f, 14624625.
    • (2003) Bioconjug Chem , vol.14 , pp. 1122-1132
    • Bellocq, N.C.1    Pun, S.H.2    Jensen, G.S.3    Davis, M.E.4
  • 41
    • 80054756400 scopus 로고    scopus 로고
    • Multistage nanovectors: from concept to novel imaging contrast agents and therapeutics
    • 10.1021/ar200077p, 3204797, 21902173
    • Godin B, Tasciotti E, Liu X, Serda RE, Ferrari M. Multistage nanovectors: from concept to novel imaging contrast agents and therapeutics. Acc Chem Res 2011, 44:979-989. 10.1021/ar200077p, 3204797, 21902173.
    • (2011) Acc Chem Res , vol.44 , pp. 979-989
    • Godin, B.1    Tasciotti, E.2    Liu, X.3    Serda, R.E.4    Ferrari, M.5
  • 43
    • 77956248928 scopus 로고    scopus 로고
    • Vectoring siRNA therapeutics into the clinic
    • 10.1038/nrclinonc.2010.131, 20798696
    • Ferrari M. Vectoring siRNA therapeutics into the clinic. Nat Rev Clin Oncol 2010, 7:485-486. 10.1038/nrclinonc.2010.131, 20798696.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 485-486
    • Ferrari, M.1
  • 46
    • 84864673390 scopus 로고    scopus 로고
    • Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model
    • 10.1371/journal.pone.0030207, 3412855, 22879872
    • Dave B, Landis MD, Dobrolecki LE, Wu MF, Zhang X, Westbrook TF, Hilsenbeck SG, Liu D, Lewis MT, Tweardy DJ, Chang JC. Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model. PLoS One 2012, 7:e30207. 10.1371/journal.pone.0030207, 3412855, 22879872.
    • (2012) PLoS One , vol.7
    • Dave, B.1    Landis, M.D.2    Dobrolecki, L.E.3    Wu, M.F.4    Zhang, X.5    Westbrook, T.F.6    Hilsenbeck, S.G.7    Liu, D.8    Lewis, M.T.9    Tweardy, D.J.10    Chang, J.C.11
  • 47
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYCinduced growth in Burkitt lymphoma cells
    • 10.1158/0008-5472.CAN-07-2462, 17942906
    • Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, Petrelli NJ, Dunn SP, Krueger LJ. MicroRNA let-7a down-regulates MYC and reverts MYCinduced growth in Burkitt lymphoma cells. Cancer Res 2007, 67:9762-9770. 10.1158/0008-5472.CAN-07-2462, 17942906.
    • (2007) Cancer Res , vol.67 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3    Yang, Q.4    Aris, V.5    Soteropoulos, P.6    Petrelli, N.J.7    Dunn, S.P.8    Krueger, L.J.9
  • 50
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines
    • 10.1210/me.2007-0022, 17312270
    • Adams BD, Furneaux H, White BA. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol 2007, 21:1132-1147. 10.1210/me.2007-0022, 17312270.
    • (2007) Mol Endocrinol , vol.21 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.