메뉴 건너뛰기




Volumn 58, Issue 5-6, 2013, Pages 363-373

Cytochrome P450 epoxygenase metabolite, 14,15-EET, protects against isoproterenol-induced cellular hypertrophy in H9c2 rat cell line

Author keywords

14,15 EET; 20 HETE; Cardiac hypertrophy; Cytochrome P450s; H9c2 cells; Isoproterenol; Soluble epoxide hydrolase

Indexed keywords

14,15 EPOXY 5,8,11 ICOSATRIENOIC ACID; 20 HYDROXYICOSATETRAENOIC ACID; ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; EPOXIDE HYDROLASE; ISOPRENALINE; MESSENGER RNA; PROTECTIVE AGENT;

EID: 84877635687     PISSN: 15371891     EISSN: 18793649     Source Type: Journal    
DOI: 10.1016/j.vph.2013.02.004     Document Type: Article
Times cited : (38)

References (53)
  • 1
    • 4444367613 scopus 로고    scopus 로고
    • Determination of interleukin-4-responsive region in the human cytochrome P450 2E1 gene promoter
    • Abdel-Razzak Z., Garlatti M., Aggerbeck M., Barouki R. Determination of interleukin-4-responsive region in the human cytochrome P450 2E1 gene promoter. Biochem. Pharmacol. 2004, 68:1371-1381.
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 1371-1381
    • Abdel-Razzak, Z.1    Garlatti, M.2    Aggerbeck, M.3    Barouki, R.4
  • 2
    • 71249135631 scopus 로고    scopus 로고
    • 3-Methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats
    • Aboutabl M.E., Zordoky B.N., El-Kadi A.O. 3-Methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats. Br. J. Pharmacol. 2009, 158:1808-1819.
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 1808-1819
    • Aboutabl, M.E.1    Zordoky, B.N.2    El-Kadi, A.O.3
  • 3
    • 79952808052 scopus 로고    scopus 로고
    • Inhibition of soluble epoxide hydrolase confers cardioprotection and prevents cardiac cytochrome P450 induction by benzo(a)pyrene
    • Aboutabl M.E., Zordoky B.N., Hammock B.D., El-Kadi A.O. Inhibition of soluble epoxide hydrolase confers cardioprotection and prevents cardiac cytochrome P450 induction by benzo(a)pyrene. J. Cardiovasc. Pharmacol. 2011, 57:273-281.
    • (2011) J. Cardiovasc. Pharmacol. , vol.57 , pp. 273-281
    • Aboutabl, M.E.1    Zordoky, B.N.2    Hammock, B.D.3    El-Kadi, A.O.4
  • 6
    • 33646794068 scopus 로고    scopus 로고
    • Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan)
    • Baldwin S.J., Bramhall J.L., Ashby C.A., Yue L., Murdock P.R., Hood S.R., Ayrton A.D., Clarke S.E. Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan). Drug Metab. Dispos. 2006, 34:1063-1069.
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 1063-1069
    • Baldwin, S.J.1    Bramhall, J.L.2    Ashby, C.A.3    Yue, L.4    Murdock, P.R.5    Hood, S.R.6    Ayrton, A.D.7    Clarke, S.E.8
  • 7
    • 0034992154 scopus 로고    scopus 로고
    • Use of real-time gene-specific polymerase chain reaction to measure RNA expression of three family members of rat cytochrome P450 4A
    • Bleicher K.B., Pippert T.R., Glaab W.E., Skopek T.R., Sina J.F., Umbenhauer D.R. Use of real-time gene-specific polymerase chain reaction to measure RNA expression of three family members of rat cytochrome P450 4A. J. Biochem. Mol. Toxicol. 2001, 15:133-142.
    • (2001) J. Biochem. Mol. Toxicol. , vol.15 , pp. 133-142
    • Bleicher, K.B.1    Pippert, T.R.2    Glaab, W.E.3    Skopek, T.R.4    Sina, J.F.5    Umbenhauer, D.R.6
  • 9
    • 33749364917 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes: central players in cardiovascular health and disease
    • Elbekai R.H., El-Kadi A.O. Cytochrome P450 enzymes: central players in cardiovascular health and disease. Pharmacol. Ther. 2006, 112:564-587.
    • (2006) Pharmacol. Ther. , vol.112 , pp. 564-587
    • Elbekai, R.H.1    El-Kadi, A.O.2
  • 10
    • 84875370693 scopus 로고    scopus 로고
    • Murine atrial HL-1 cell line is a reliable model to study drug metabolizing enzymes in the heart
    • Elshenawy O.H., Anwar-Mohamed A., Abdelhamid G., El-Kadi A.O. Murine atrial HL-1 cell line is a reliable model to study drug metabolizing enzymes in the heart. Vascul. Pharmacol. 2013, 58:326-333.
    • (2013) Vascul. Pharmacol. , vol.58 , pp. 326-333
    • Elshenawy, O.H.1    Anwar-Mohamed, A.2    Abdelhamid, G.3    El-Kadi, A.O.4
  • 12
    • 19444371555 scopus 로고    scopus 로고
    • Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis
    • Grygielko E.T., Martin W.M., Tweed C., Thornton P., Harling J., Brooks D.P., Laping N.J. Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis. J. Pharmacol. Exp. Ther. 2005, 313:943-951.
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , pp. 943-951
    • Grygielko, E.T.1    Martin, W.M.2    Tweed, C.3    Thornton, P.4    Harling, J.5    Brooks, D.P.6    Laping, N.J.7
  • 13
    • 0034973773 scopus 로고    scopus 로고
    • Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity
    • Guengerich F.P. Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. Chem. Res. Toxicol. 2001, 14:611-650.
    • (2001) Chem. Res. Toxicol. , vol.14 , pp. 611-650
    • Guengerich, F.P.1
  • 15
    • 0036179501 scopus 로고    scopus 로고
    • Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension
    • Imig J.D., Zhao X., Capdevila J.H., Morisseau C., Hammock B.D. Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension. Hypertension 2002, 39:690-694.
    • (2002) Hypertension , vol.39 , pp. 690-694
    • Imig, J.D.1    Zhao, X.2    Capdevila, J.H.3    Morisseau, C.4    Hammock, B.D.5
  • 16
    • 0036707620 scopus 로고    scopus 로고
    • Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats
    • Kalsotra A., Anakk S., Boehme C.L., Strobel H.W. Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats. Drug Metab. Dispos. 2002, 30:1022-1028.
    • (2002) Drug Metab. Dispos. , vol.30 , pp. 1022-1028
    • Kalsotra, A.1    Anakk, S.2    Boehme, C.L.3    Strobel, H.W.4
  • 17
    • 3543082100 scopus 로고    scopus 로고
    • Differential effects of mercury, lead and copper on the constitutive and inducible expression of aryl hydrocarbon receptor (AHR)-regulated genes in cultured hepatoma Hepa 1c1c7 cells
    • Korashy H.M., El-Kadi A.O. Differential effects of mercury, lead and copper on the constitutive and inducible expression of aryl hydrocarbon receptor (AHR)-regulated genes in cultured hepatoma Hepa 1c1c7 cells. Toxicology 2004, 201:153-172.
    • (2004) Toxicology , vol.201 , pp. 153-172
    • Korashy, H.M.1    El-Kadi, A.O.2
  • 18
    • 0036645337 scopus 로고    scopus 로고
    • Transforming growth factor-beta function blocking prevents myocardial fibrosis and diastolic dysfunction in pressure-overloaded rats
    • Kuwahara F., Kai H., Tokuda K., Kai M., Takeshita A., Egashira K., Imaizumi T. Transforming growth factor-beta function blocking prevents myocardial fibrosis and diastolic dysfunction in pressure-overloaded rats. Circulation 2002, 106:130-135.
    • (2002) Circulation , vol.106 , pp. 130-135
    • Kuwahara, F.1    Kai, H.2    Tokuda, K.3    Kai, M.4    Takeshita, A.5    Egashira, K.6    Imaizumi, T.7
  • 21
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 22
    • 78650798184 scopus 로고    scopus 로고
    • Metabolic activity and mRNA levels of human cardiac CYP450s involved in drug metabolism
    • Michaud V., Frappier M., Dumas M.C., Turgeon J. Metabolic activity and mRNA levels of human cardiac CYP450s involved in drug metabolism. PLoS One 2010, 5:e15666.
    • (2010) PLoS One , vol.5
    • Michaud, V.1    Frappier, M.2    Dumas, M.C.3    Turgeon, J.4
  • 23
    • 27744551500 scopus 로고    scopus 로고
    • Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system
    • Miyata N., Roman R.J. Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system. J. Smooth Muscle Res. 2005, 41:175-193.
    • (2005) J. Smooth Muscle Res. , vol.41 , pp. 175-193
    • Miyata, N.1    Roman, R.J.2
  • 26
    • 34250731775 scopus 로고    scopus 로고
    • Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha
    • Ng V.Y., Huang Y., Reddy L.M., Falck J.R., Lin E.T., Kroetz D.L. Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha. Drug Metab. Dispos. 2007, 35:1126-1134.
    • (2007) Drug Metab. Dispos. , vol.35 , pp. 1126-1134
    • Ng, V.Y.1    Huang, Y.2    Reddy, L.M.3    Falck, J.R.4    Lin, E.T.5    Kroetz, D.L.6
  • 27
    • 79956311708 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-gamma downregulates soluble epoxide hydrolase in cardiomyocytes
    • Pang W., Li N., Ai D., Niu X.L., Guan Y.F., Zhu Y. Activation of peroxisome proliferator-activated receptor-gamma downregulates soluble epoxide hydrolase in cardiomyocytes. Clin. Exp. Pharmacol. Physiol. 2011, 38:358-364.
    • (2011) Clin. Exp. Pharmacol. Physiol. , vol.38 , pp. 358-364
    • Pang, W.1    Li, N.2    Ai, D.3    Niu, X.L.4    Guan, Y.F.5    Zhu, Y.6
  • 29
    • 0034307196 scopus 로고    scopus 로고
    • Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2
    • Peng H.M., Coon M.J. Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2. Arch. Biochem. Biophys. 2000, 382:129-137.
    • (2000) Arch. Biochem. Biophys. , vol.382 , pp. 129-137
    • Peng, H.M.1    Coon, M.J.2
  • 30
    • 25444480317 scopus 로고    scopus 로고
    • Downregulation of the atrial natriuretic peptide/natriuretic peptide receptor-C system in the early stages of diabetic retinopathy in the rat
    • Rollin R., Mediero A., Fernandez-Cruz A., Fernandez-Durango R. Downregulation of the atrial natriuretic peptide/natriuretic peptide receptor-C system in the early stages of diabetic retinopathy in the rat. Mol. Vis. 2005, 11:216-224.
    • (2005) Mol. Vis. , vol.11 , pp. 216-224
    • Rollin, R.1    Mediero, A.2    Fernandez-Cruz, A.3    Fernandez-Durango, R.4
  • 31
    • 0036080081 scopus 로고    scopus 로고
    • P-450 metabolites of arachidonic acid in the control of cardiovascular function
    • Roman R.J. P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol. Rev. 2002, 82:131-185.
    • (2002) Physiol. Rev. , vol.82 , pp. 131-185
    • Roman, R.J.1
  • 32
    • 0036783335 scopus 로고    scopus 로고
    • Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes
    • Rushmore T.H., Kong A.N. Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes. Curr. Drug Metab. 2002, 3:481-490.
    • (2002) Curr. Drug Metab. , vol.3 , pp. 481-490
    • Rushmore, T.H.1    Kong, A.N.2
  • 33
    • 0033009103 scopus 로고    scopus 로고
    • P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues
    • Scarborough P.E., Ma J., Qu W., Zeldin D.C. P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues. Drug Metab. Rev. 1999, 31:205-234.
    • (1999) Drug Metab. Rev. , vol.31 , pp. 205-234
    • Scarborough, P.E.1    Ma, J.2    Qu, W.3    Zeldin, D.C.4
  • 34
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen T.D., Livak K.J. Analyzing real-time PCR data by the comparative C(T) method. Nat. Protoc. 2008, 3:1101-1108.
    • (2008) Nat. Protoc. , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 39
    • 0242720683 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function
    • Spector A.A., Fang X., Snyder G.D., Weintraub N.L. Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function. Prog. Lipid Res. 2004, 43:55-90.
    • (2004) Prog. Lipid Res. , vol.43 , pp. 55-90
    • Spector, A.A.1    Fang, X.2    Snyder, G.D.3    Weintraub, N.L.4
  • 41
    • 0034681831 scopus 로고    scopus 로고
    • Gene expression in distinct regions of the heart
    • Thum T., Borlak J. Gene expression in distinct regions of the heart. Lancet 2000, 355:979-983.
    • (2000) Lancet , vol.355 , pp. 979-983
    • Thum, T.1    Borlak, J.2
  • 42
    • 0033838338 scopus 로고    scopus 로고
    • Cytochrome P450 mono-oxygenase gene expression and protein activity in cultures of adult cardiomyocytes of the rat
    • Thum T., Borlak J. Cytochrome P450 mono-oxygenase gene expression and protein activity in cultures of adult cardiomyocytes of the rat. Br. J. Pharmacol. 2000, 130:1745-1752.
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 1745-1752
    • Thum, T.1    Borlak, J.2
  • 43
    • 0036793580 scopus 로고    scopus 로고
    • Testosterone, cytochrome P450, and cardiac hypertrophy
    • Thum T., Borlak J. Testosterone, cytochrome P450, and cardiac hypertrophy. FASEB J. 2002, 16:1537-1549.
    • (2002) FASEB J. , vol.16 , pp. 1537-1549
    • Thum, T.1    Borlak, J.2
  • 44
    • 0030063499 scopus 로고    scopus 로고
    • Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart
    • Wu S., Moomaw C.R., Tomer K.B., Falck J.R., Zeldin D.C. Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. J. Biol. Chem. 1996, 271:3460-3468.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3460-3468
    • Wu, S.1    Moomaw, C.R.2    Tomer, K.B.3    Falck, J.R.4    Zeldin, D.C.5
  • 46
    • 23344450788 scopus 로고    scopus 로고
    • Induction of phase I, II and III drug metabolism/transport by xenobiotics
    • Xu C., Li C.Y., Kong A.N. Induction of phase I, II and III drug metabolism/transport by xenobiotics. Arch. Pharm. Res. 2005, 28:249-268.
    • (2005) Arch. Pharm. Res. , vol.28 , pp. 249-268
    • Xu, C.1    Li, C.Y.2    Kong, A.N.3
  • 49
    • 0029122098 scopus 로고
    • Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform
    • Zeldin D.C., DuBois R.N., Falck J.R., Capdevila J.H. Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. Arch. Biochem. Biophys. 1995, 322:76-86.
    • (1995) Arch. Biochem. Biophys. , vol.322 , pp. 76-86
    • Zeldin, D.C.1    DuBois, R.N.2    Falck, J.R.3    Capdevila, J.H.4
  • 50
    • 35148827377 scopus 로고    scopus 로고
    • H9c2 cell line is a valuable in vitro model to study the drug metabolizing enzymes in the heart
    • Zordoky B.N., El-Kadi A.O. H9c2 cell line is a valuable in vitro model to study the drug metabolizing enzymes in the heart. J. Pharmacol. Toxicol. Methods 2007, 56:317-322.
    • (2007) J. Pharmacol. Toxicol. Methods , vol.56 , pp. 317-322
    • Zordoky, B.N.1    El-Kadi, A.O.2
  • 51
    • 77649184815 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin and beta-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism
    • Zordoky B.N., El-Kadi A.O. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and beta-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism. Toxicol. In Vitro 2010, 24:863-871.
    • (2010) Toxicol. In Vitro , vol.24 , pp. 863-871
    • Zordoky, B.N.1    El-Kadi, A.O.2
  • 52
    • 54349101231 scopus 로고    scopus 로고
    • Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats
    • Zordoky B.N., Aboutabl M.E., El-Kadi A.O. Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats. Drug Metab. Dispos. 2008, 36:2277-2286.
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 2277-2286
    • Zordoky, B.N.1    Aboutabl, M.E.2    El-Kadi, A.O.3
  • 53
    • 79960610491 scopus 로고    scopus 로고
    • Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver
    • Zordoky B.N., Anwar-Mohamed A., Aboutabl M.E., El-Kadi A.O. Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver. Drug Metab. Dispos. 2011, 39:1440-1450.
    • (2011) Drug Metab. Dispos. , vol.39 , pp. 1440-1450
    • Zordoky, B.N.1    Anwar-Mohamed, A.2    Aboutabl, M.E.3    El-Kadi, A.O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.