Transforming growth factor-β function blocking prevents myocardial fibrosis and diastolic dysfunction in pressure-overloaded rats

Circulation

Volumn 106, Issue 1, 2002, Pages 130-135

  Kuwahara, Fumitaka ^a   Kai, Hisashi ^a   Tokuda, Keisuke ^a   Kai, Mamiko ^a   Takeshita, Akira ^a   Egashira, Kensuke ^a   Imaizumi, Tsutomu ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Diastole; Fibrosis; Growth substances; Hypertension

Indexed keywords

MESSENGER RNA; NEUTRALIZING ANTIBODY; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW VELOCITY; CELL ACTIVATION; CONTROLLED STUDY; FIBROBLAST; FIBROGENESIS; HEART MUSCLE FIBROSIS; HEART VENTRICLE OVERLOAD; HEART VENTRICLE REMODELING; HEMODYNAMICS; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES; CARDIOMEGALY; DIASTOLE; FIBROBLASTS; FIBROSIS; HEMODYNAMIC PROCESSES; HYPERTENSION; KINETICS; MALE; MYOCARDIUM; PRESSURE; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; VENTRICULAR DYSFUNCTION, LEFT;

EID: 0036645337     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000020689.12472.E0     Document Type: Article

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